Cardiac troponin T: a useful early marker for cardiac and respiratory dysfunction in neonates.

abstract：BACKGROUND:Genetic processes underlying fetal lung development and maturation are incompletely understood. Better knowledge of these processes would provide insights into the causes of lung malformations and prevention of respiratory distress syndrome and the potential adverse effects of glucocorticoids. Hox genes are ...

journal_title：Neonatology

authors： Grier DG,Thompson A,Lappin TR,Halliday HL

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Targeted milrinone treatment for low left ventricular output (LVO) reduces the incidence of acute cardiorespiratory instability following ligation of patent ductus arteriosus (PDA) in preterm infants. Despite this, some infants continue to experience postoperative deterioration. Adrenal insufficiency related...

journal_title：Neonatology

authors： EL-Khuffash A,McNamara PJ,Lapointe A,Jain A

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Alveolar development and lung parenchymal simplification are not well characterized in vivo in neonatal patients with respiratory morbidities, such as bronchopulmonary dysplasia (BPD). Hyperpolarized (HP) gas diffusion magnetic resonance imaging (MRI) is a sensitive, safe, nonionizing, and noninvasive biomar...

journal_title：Neonatology

authors： Higano NS,Thomen RP,Quirk JD,Huyck HL,Hahn AD,Fain SB,Pryhuber GS,Woods JC

更新日期：2020-11-11 00:00:00

abstract：:Despite recent advances in the perinatal management of neonatal respiratory distress syndrome (RDS), controversies still exist. We report the updated recommendations of a European panel of expert neonatologists who had developed consensus guidelines after critical examination of the most up-to-date evidence in 2007. T...

journal_title：Neonatology

authors： Sweet DG,Carnielli V,Greisen G,Hallman M,Ozek E,Plavka R,Saugstad OD,Simeoni U,Speer CP,Halliday HL,European Association of Perinatal Medicine.

更新日期：2010-06-01 00:00:00

abstract：:This paper describes a neonate with type II Gaucher disease. The phenotype was unusually severe with congenital ichthyosis, hepatosplenomegaly, muscular hypotonia, myoclonus and respiratory failure. Electron microscopy of the skin revealed lamellar body contents in the stratum corneum interstices, appearances consider...

journal_title：Neonatology

authors： Haverkaemper S,Marquardt T,Hausser I,Timme K,Kuehn T,Hertzberg C,Rossi R

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Doxapram has been advocated as a treatment for persistent apnea of prematurity (AOP). OBJECTIVE:To evaluate the effect of doxapram on long-term neurodevelopmental outcome in preterm infants as its safety still needs to be established. METHODS:From a retrospective cohort of preterm infants with a gestationa...

journal_title：Neonatology

authors： Ten Hove CH,Vliegenthart RJ,Te Pas AB,Brouwer E,Rijken M,van Wassenaer-Leemhuis AG,van Kaam AH,Onland W

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVES:To compare the ultrasound examination with pH-metry in order to evaluate the diagnostic accuracy of sonography for diagnosis of gastro-oesophageal reflux (GOR) in preterm infants. METHODS:A prospective study was conducted on 31 premature infants <34 weeks with clinically diagnosed GOR. First, they underwent...

journal_title：Neonatology

authors： Pezzati M,Filippi L,Psaraki M,Rossi S,Dani C,Tronchin M,Rubaltelli FF

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:To examine the impact of medical complexity among very preterm infants on health care resource use, family, and neurodevelopmental outcomes at 18 months' corrected age. METHODS:This observational cohort study of Canadian infants born < 29 weeks' gestational age in 2009-2011 compared infants with and those wi...

journal_title：Neonatology

authors： Nassel D,Chartrand C,Doré-Bergeron MJ,Lefebvre F,Ballantyne M,Van Overmeire B,Luu TM,on behalf of the Canadian Neonatal Network and the Canadian Neonatal Follow-Up Network.

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Extreme hyperbilirubinemia is treated with double volume exchange transfusion, which may take hours to commence. A neuroprotective agent that could be administered immediately might be clinically useful. Minocycline, an anti-inflammatory and anti-apoptotic semisynthetic tetracycline, prevents hyperbilirubine...

journal_title：Neonatology

authors： Geiger AS,Rice AC,Shapiro SM

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Hyperglycaemia is a common complication of prematurity and is associated with neonatal mortality and morbidity, yet the aetiology is incompletely understood. C-peptide has been used in adults to estimate endogenous insulin secretion due to its simple clearance kinetics. OBJECTIVE:To determine insulin secret...

journal_title：Neonatology

authors： Dickson JL,Chase JG,Pretty CG,Gunn CA,Alsweiler JM

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:Oral propranolol has improved the treatment of infantile hemangiomas, and a pediatric oral solution of propranolol has recently been licensed in the USA and Europe. In very preterm infants, infantile hemangiomas are associated with the occurrence of retinopathy of prematurity (ROP), and both diseases share...

journal_title：Neonatology

authors： Bührer C,Bassler D

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a common enzyme deficiency affecting more than 300 million individuals worldwide. Extreme neonatal hyperbilirubinemia, with its severe sequelae of bilirubin neurotoxicity and the potential of death, is the most devastating manifestation of G6PD deficienc...

journal_title：Neonatology

authors： Kaplan M,Wong RJ,Stevenson DK

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Faecal calprotectin has been proposed as a sensitive marker for gastrointestinal inflammation in children and adults. High levels have been reported in healthy newborns and during the first months of life; the effect of the kind of feeding on the calprotectin concentration in stools is controversial. OBJECT...

journal_title：Neonatology

authors： Savino F,Castagno E,Calabrese R,Viola S,Oggero R,Miniero R

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Congenital diaphragmatic hernia (CDH) is an abnormal development of the diaphragm leading to high neonatal mortality and morbidity. Beyond the neonatal period, prospective data on overall long-term outcome in CDH survivors is scarce. In particular, for those treated with fetoscopic endoluminal tracheal occlu...

journal_title：Neonatology

authors： Van Ginderdeuren E,Allegaert K,Decaluwe H,Deprest J,Debeer A,Proesmans M

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:While hypoxic events with bradycardias are a frequent occurrence during the first weeks of life in preterm infants, the impact of preterm birth on maturation of the cardiovascular response to hypoxia in early postnatal life is unknown. OBJECTIVES:In the present study, we tested the hypothesis that preterm b...

journal_title：Neonatology

authors： Pladys P,Arsenault J,Reix P,Rouillard Lafond J,Moreau-Bussière F,Praud JP

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Clinical illness caused by resistant bacteria usually represents a wider problem of asymptomatic colonization. Active surveillance with appropriate institution of isolation precautions represents a potential mechanism to control colonization and reduce infection. The neonatal intensive care unit (NICU) is an...

journal_title：Neonatology

authors： Benenson S,Levin PD,Block C,Adler A,Ergaz Z,Peleg O,Minster N,Gross I,Schaffer K,Moses AE,Cohen MJ

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Recently, sustained inflations (SI) during chest compression (CC) (CC+SI) have been suggested as an alternative to the current approach during neonatal resuscitation. No previous study compared CC+SI using CC rates of 90/min to the current 3:1 compression:ventilation ratio (C:V). OBJECTIVE:To determine whet...

journal_title：Neonatology

authors： Li ES,Görens I,Cheung PY,Lee TF,Lu M,O'Reilly M,Schmölzer GM

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Eye drop treatment routinely used to obtain mydriasis prior to fundoscopy in neonates requires repeated instillations of mydriatic agents that can lead to systemic side effects. OBJECTIVES:The aim of this study was to compare the mydriatic efficacy and tolerance of administration of phenylephrine and tropic...

journal_title：Neonatology

authors： Bremond-Gignac D,Jacqz-Aigrain E,Abdoul H,Daruich A,Beresniak A,Baud O,Alberti C,on behalf of the CLAIR FO Study Group.

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Apnea of prematurity (AOP) occurs frequently in preterm infants and a variable proportion of AOP can be induced by gastroesophageal reflux (GER). Conservative treatment, including dietary modifications, should be the first-line approach for both GER and GER-related apneas in this population. OBJECTIVES:To e...

journal_title：Neonatology

authors： Corvaglia L,Spizzichino M,Aceti A,Legnani E,Mariani E,Martini S,Battistini B,Faldella G

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:For quick detection or exclusion of neonatal early-onset bacterial infection (EOBI) or late-onset bacterial infection (LOBI), interleukin (IL)-6 is used. Its clinical use is sometimes limited due to prolonged recall times. Therefore, an IL-6 bedside test was established. OBJECTIVE:To compare the diagnostic ...

journal_title：Neonatology

authors： Batfalsky A,Lohr A,Heussen N,Neunhoeffer F,Orlikowsky TW

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Hypoxic-ischaemic encephalopathy is a major cause of neurologic impairment and mortality in neonates. Early knowledge of brain injury is important to guide therapeutic decisions and reliably inform the parents. Increased secretoneurin levels have been detected in adult patients suffering from brain injury an...

journal_title：Neonatology

authors： Wechselberger K,Schmid A,Posod A,Höck M,Neubauer V,Fischer-Colbrie R,Kiechl-Kohlendorfer U,Griesmaier E

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Sustained lung inflation (SLI) applied at birth has been demonstrated to lead to clearance of lung fluid and achievement of a precocious functional residual capacity in animal studies. OBJECTIVES:To verify if the application of SLI in preterm infants at birth may reduce the need for mechanical ventilation a...

journal_title：Neonatology

authors： Lista G,Fontana P,Castoldi F,Cavigioli F,Dani C

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The causes of bronchopulmonary dysplasia (BPD) are multifactorial. Overdistension of the lung (volutrauma) is considered an important contribution. As an alternative to traditional pressure-limited ventilation (PLV), modern neonatal ventilators offer modes which can target a set tidal volume. OBJECTIVES:To ...

journal_title：Neonatology

authors： Wheeler KI,Klingenberg C,Morley CJ,Davis PG

更新日期：2011-01-01 00:00:00

abstract：UNLABELLED:Near-infrared spectroscopy-derived regional tissue oxygen saturation of haemoglobin (rStO2) reflects venous oxygen saturation. If cerebral metabolism is stable, rStO2 can be used as an estimate of cerebral oxygen delivery. The SafeBoosC phase II randomised clinical trial hypothesises that the burden of hypo-...

journal_title：Neonatology

authors： Pellicer A,Greisen G,Benders M,Claris O,Dempsey E,Fumagalli M,Gluud C,Hagmann C,Hellström-Westas L,Hyttel-Sorensen S,Lemmers P,Naulaers G,Pichler G,Roll C,van Bel F,van Oeveren W,Skoog M,Wolf M,Austin T

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Endogenous carbon monoxide (CO) production is primarily due to heme degradation, which also results in the equimolar production of bilirubin. Thus, estimates of total body CO production can serve as indices of total body bilirubin formation. The elimination rate of CO from a person's body (CO washout rate) a...

journal_title：Neonatology

authors： Stevenson DK,Wong RJ,Ostrander CR,Maric I,Vreman HJ,Cohen RS

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Schistocytes are circulating erythrocyte fragments. They can be identified microscopically from a blood smear; but automated systems evaluate more cells and avoid inconsistencies in microscopy. Studies using adult subjects indicate that automated quantification of schistocytes can be clinically useful. Howev...

journal_title：Neonatology

authors： Judkins AJ,MacQueen BC,Christensen RD,Henry E,Snow GL,Bennett ST

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Numerous studies in cultured cells indicate that damage to mitochondrial DNA (mtDNA) dictates cellular responses to oxidant stress, yet the consequences of mtDNA damage have not been studied directly in the preterm lung. OBJECTIVE:We sought to determine whether hyperoxia-induced fetal lung dysmorphogenesis ...

journal_title：Neonatology

authors： Gebb SA,Decoux A,Waggoner A,Wilson GL,Gillespie MN

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:In the absence of universal screening for congenital cytomegalovirus (cCMV) infection, the aim of this study was to assess the outcomes of a targeted screening protocol based on maternal and neonatal risk indicators. METHODS:The medical records of 2,623 neonates born in our maternal hospital between June 20...

journal_title：Neonatology

authors： Levit Y,Dym L,Yochpaz S,Manor Y,Adler A,Halutz O,Grisaru-Soen G,Herzlich J,Marom R

更新日期：2020-12-22 00:00:00

abstract：BACKGROUND:Bronchopulmonary dysplasia (BPD), severe retinopathy of prematurity (sROP), and cystic periventricular leukomalacia (cPVL) are 3 major morbidities with long-term neurodevelopmental impairments in preterm infants. OBJECTIVE:To investigate the strength of associations and identify key risk factors shared by B...

journal_title：Neonatology

authors： Wang LW,Lin YC,Wang ST,Huang CC,on behalf of the Taiwan Premature Infant Developmental Collaborative Study Group.

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Refinement of ventilatory techniques remains a challenge given the persistence of chronic lung disease of preterm infants. METHODS:To test the hypothesis that proportional assist ventilation (PAV) will allow to lower the ventilator pressure at equivalent fractions of inspiratory oxygen (FiO(2)) and arterial...

journal_title：Neonatology

authors： Schulze A,Rieger-Fackeldey E,Gerhardt T,Claure N,Everett R,Bancalari E

更新日期：2007-01-01 00:00:00