European consensus guidelines on the management of neonatal respiratory distress syndrome in preterm infants - 2010 update.

abstract：:The treatment of preterm newborn rabbits with synthetic surfactants containing simple phospholipid mixtures and peptides gives similar tidal volumes to treatment with poractant alfa (Curosurf®). The addition of both surfactant protein B and C analogs to the phospholipid mixture will stabilize the alveoli, measured as ...

journal_title：Neonatology

authors： Curstedt T,Calkovska A,Johansson J

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:Oral propranolol has improved the treatment of infantile hemangiomas, and a pediatric oral solution of propranolol has recently been licensed in the USA and Europe. In very preterm infants, infantile hemangiomas are associated with the occurrence of retinopathy of prematurity (ROP), and both diseases share...

journal_title：Neonatology

authors： Bührer C,Bassler D

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Although liver can be injured under the hypoxic-ischemic encephalopathy (HIE) condition, there is currently no histopathological evidence. Therapeutic hypothermia is used to protect the brain; however, the therapeutic potential for concomitant liver injury is unknown. OBJECTIVES:This study aimed to histopat...

journal_title：Neonatology

authors： Kubo H,Shimono R,Nakamura S,Koyano K,Jinnai W,Yamato S,Yasuda S,Nakamura M,Tanaka A,Fujii T,Kanenishi K,Chiba Y,Miki T,Kusaka T,Ueno M

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Alveolar development and lung parenchymal simplification are not well characterized in vivo in neonatal patients with respiratory morbidities, such as bronchopulmonary dysplasia (BPD). Hyperpolarized (HP) gas diffusion magnetic resonance imaging (MRI) is a sensitive, safe, nonionizing, and noninvasive biomar...

journal_title：Neonatology

authors： Higano NS,Thomen RP,Quirk JD,Huyck HL,Hahn AD,Fain SB,Pryhuber GS,Woods JC

更新日期：2020-11-11 00:00:00

abstract：BACKGROUND:Premature birth is a significant health care burden. Xenon (Xe) is a general anesthetic with neuroprotective effects. OBJECTIVES:Here, we investigate the neuroprotective role of Xe in a lipopolysaccharide (LPS)- and hypoxia-ischemia (HI)-induced white matter damage (WMD) model. METHODS:Three-day-old Spragu...

journal_title：Neonatology

authors： Yin X,Zhao J,Jiang H,Li L,Jiang J,Xi H,Peng X,Yin X,Shi X,Zhang L

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Nosocomial infections endanger preterm infants. OBJECTIVE:The aim of the present controlled randomized trial was to investigate whether Bifidobacterium lactis reduces the incidence of nosocomial infections in infants with very low birth weight (VLBW; <1,500 g) <30 weeks of gestation. PATIENTS AND METHODS:I...

journal_title：Neonatology

authors： Mihatsch WA,Vossbeck S,Eikmanns B,Hoegel J,Pohlandt F

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Phenobarbital and midazolam are commonly used drugs in (near-)term neonates treated with therapeutic hypothermia for hypoxic-ischaemic encephalopathy, for sedation, and/or as anti-epileptic drug. Phenobarbital is an inducer of cytochrome P450 (CYP) 3A, while midazolam is a CYP3A substrate. Therefore, co-trea...

journal_title：Neonatology

authors： Favié LMA,Groenendaal F,van den Broek MPH,Rademaker CMA,de Haan TR,van Straaten HLM,Dijk PH,van Heijst A,Simons SHP,Dijkman KP,Rijken M,Zonnenberg IA,Cools F,Zecic A,van der Lee JH,Nuytemans DHGM,van Bel F,Egberts TCG,

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Corticosteroids have been used widely after birth in preterm infants with respiratory failure; hydrocortisone may be preferable to other corticosteroids for this purpose. OBJECTIVES:To determine if postnatal hydrocortisone is useful to prevent or treat bronchopulmonary dysplasia (BPD) in preterm infants. M...

journal_title：Neonatology

authors： Doyle LW,Ehrenkranz RA,Halliday HL

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Umbilical arterial catheters (UACs) are frequently used in critically ill neonates. UAC are convenient, reliable, and allow for caregiver convenience in performing painless arterial blood sampling. We hypothesized that UAC removal in extremely low birth weight (ELBW) neonates will result in significantly les...

journal_title：Neonatology

authors： Carroll PD,Zimmerman MB,Nalbant D,Gingerich EL,An G,Cress GA,Veng-Pedersen P,Widness JA

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Apnea of prematurity (AOP) occurs frequently in preterm infants and a variable proportion of AOP can be induced by gastroesophageal reflux (GER). Conservative treatment, including dietary modifications, should be the first-line approach for both GER and GER-related apneas in this population. OBJECTIVES:To e...

journal_title：Neonatology

authors： Corvaglia L,Spizzichino M,Aceti A,Legnani E,Mariani E,Martini S,Battistini B,Faldella G

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate whether a new MRI scoring system for preterm non-haemorrhagic white matter injury (WMI), derived from the analysis of the natural evolution of WMI throughout the neonatal period until term-equivalent age, can be used for outcome prediction. METHODS:Eighty-two infants <36...

journal_title：Neonatology

authors： Martinez-Biarge M,Groenendaal F,Kersbergen KJ,Benders MJNL,Foti F,van Haastert IC,Cowan FM,de Vries LS

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Caffeine is a commonly used drug for apnea of prematurity. It may, however, also have a beneficial effect on bronchopulmonary dysplasia (BPD), which is the most common complication of extreme preterm birth. OBJECTIVES:To study the inflammatory, structural and functional effects of caffeine in an animal mode...

journal_title：Neonatology

authors： Nagatomo T,Jiménez J,Richter J,De Baere S,Vanoirbeek J,Naulaers G,Allegaert K,Croubels S,Deprest JA,Toelen J

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Retinopathy of prematurity (ROP) is a sight-threatening disease affecting extremely preterm infants. The introduction of new ROP screening surveillance systems, with higher sensitivity and specificity than established ROP screening guidelines, has the potential to reduce the number of stressful eye examinati...

journal_title：Neonatology

authors： Lundgren P,Stoltz Sjöström E,Domellöf M,Smith L,Wu C,VanderVeen D,Hellström A,Löfqvist C

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Periventricular white matter (PWM) is particularly vulnerable in very preterm infants. Non-cystic white matter injury, known as non-cystic periventricular leukomalacia (ncPVL), is the commonest 'lesion' affecting the preterm brain. There is no consensus about whether ncPVL can be reliably identified from cer...

journal_title：Neonatology

authors： Graça AM,Cardoso K,Costa J,Cowan F

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Recent studies indicate an increasing use of less invasive surfactant administration. Different techniques have been shown with distinct risks and benefits. The aim of this study was to develop a new method that simplifies this procedure. OBJECTIVES:An applicator was developed and tested on a manikin to mak...

journal_title：Neonatology

authors： Maiwald CA,Neuberger P,Vochem M,Poets C

更新日期：2017-01-01 00:00:00

abstract：AIM:To determine the prevalence of renal anomalies in patients with an isolated single umbilical artery (SUA). METHODS:We performed a retrospective study of all renal ultrasound examinations assessed at our centre between January 1998 and December 2008 in neonates with SUA with or without associated anomalies. RESULT...

journal_title：Neonatology

authors： de Boom ML,Kist-van Holthe JE,Sramek A,Lardenoye SW,Walther FJ,Lopriore E

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Around 10% of newborn infants require assistance during transition after birth. Heart rate (HR) is the most important clinical indicator to evaluate the clinical status of a newborn. AIM:Our study aimed to review all established and novel methods to detect HR in babies giving special consideration to non-in...

journal_title：Neonatology

authors： Anton O,Fernandez R,Rendon-Morales E,Aviles-Espinosa R,Jordan H,Rabe H

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Bronchopulmonary dysplasia (BPD), severe retinopathy of prematurity (sROP), and cystic periventricular leukomalacia (cPVL) are 3 major morbidities with long-term neurodevelopmental impairments in preterm infants. OBJECTIVE:To investigate the strength of associations and identify key risk factors shared by B...

journal_title：Neonatology

authors： Wang LW,Lin YC,Wang ST,Huang CC,on behalf of the Taiwan Premature Infant Developmental Collaborative Study Group.

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Substantial health care resources are expended on standardised formal neonatal resuscitation training (SFNRT) programmes, but their effectiveness has not been proven. OBJECTIVES:To determine whether SFNRT programmes reduce neonatal mortality and morbidity, improve acquisition and retention of knowledge and ...

journal_title：Neonatology

authors： Pammi M,Dempsey EM,Ryan CA,Barrington KJ

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:We hypothesized that color Doppler-measured cerebral blood flow velocity (CD-CBFV) as measured in the three feeding arteries of the brain can be used as an estimator of global cerebral blood flow. PATIENTS AND METHODS:CD-CBFV was determined as soon as possible after determination of phase-contrast magnetic ...

journal_title：Neonatology

authors： Benders MJ,Hendrikse J,de Vries L,Groenendaal F,van Bel F

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Newborns are susceptible to inflammatory diseases due to defects in clearing activated immune cells from tissues. Therefore, mechanisms have likely evolved to protect neonates from leukocyte-mediated cytotoxicity. Bilirubin has antioxidant activity, and it is possible that it also exerts effects on cellular ...

journal_title：Neonatology

authors： Weinberger B,Archer FE,Kathiravan S,Hirsch DS,Kleinfeld AM,Vetrano AM,Hegyi T

更新日期：2013-01-01 00:00:00

abstract：:Rites of passage mark important changes during human life and, for the neonate, its transition from intrauterine life into society. Their original intent was to purify the body from blood and meconium. But the cleansing rites had a spiritual dimension from the very start. When the rites of Mesopotamian, Egyptian, Jewi...

journal_title：Neonatology

authors： Obladen M

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Nasal continuous positive airway pressure (NCPAP) is a well-studied treatment for respiratory problems in preterm infants. However, the best strategy for NCPAP weaning is unknown. OBJECTIVE:We aimed to compare the success of progressive pressure wean versus sudden wean for discontinuation of NCPAP in preter...

journal_title：Neonatology

authors： Lemieux-Bourque C,Piedboeuf B,Fontela PS,Bornais K,Beltempo M

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:The causes of bronchopulmonary dysplasia (BPD) are multifactorial. Overdistension of the lung (volutrauma) is considered an important contribution. As an alternative to traditional pressure-limited ventilation (PLV), modern neonatal ventilators offer modes which can target a set tidal volume. OBJECTIVES:To ...

journal_title：Neonatology

authors： Wheeler KI,Klingenberg C,Morley CJ,Davis PG

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Streptococcus agalactiae (group B Streptococcus, GBS) is the most common cause of early neonatal infection, but restricting the diagnosis to culture-positive infants may underestimate the burden of GBS disease. Our objective was to determine whether maternal GBS colonization was associated with an increased ...

journal_title：Neonatology

authors： Brigtsen AK,Jacobsen AF,Dedi L,Melby KK,Fugelseth D,Whitelaw A

更新日期：2015-01-01 00:00:00

abstract：UNLABELLED:Near-infrared spectroscopy-derived regional tissue oxygen saturation of haemoglobin (rStO2) reflects venous oxygen saturation. If cerebral metabolism is stable, rStO2 can be used as an estimate of cerebral oxygen delivery. The SafeBoosC phase II randomised clinical trial hypothesises that the burden of hypo-...

journal_title：Neonatology

authors： Pellicer A,Greisen G,Benders M,Claris O,Dempsey E,Fumagalli M,Gluud C,Hagmann C,Hellström-Westas L,Hyttel-Sorensen S,Lemmers P,Naulaers G,Pichler G,Roll C,van Bel F,van Oeveren W,Skoog M,Wolf M,Austin T

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Refinement of ventilatory techniques remains a challenge given the persistence of chronic lung disease of preterm infants. METHODS:To test the hypothesis that proportional assist ventilation (PAV) will allow to lower the ventilator pressure at equivalent fractions of inspiratory oxygen (FiO(2)) and arterial...

journal_title：Neonatology

authors： Schulze A,Rieger-Fackeldey E,Gerhardt T,Claure N,Everett R,Bancalari E

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Inhaled glucocorticoids may increase the risk of pneumonia in adults. Thus, respiratory infections may be a potential explanation for the non-significantly increased mortality seen in the glucocorticoid group in the largest randomized trial on inhaled glucocorticoids for preventing bronchopulmonary dysplasia...

journal_title：Neonatology

authors： Koch A,Kreutzer K,von Oldershausen G,Poets CF,Bassler D,NEuroSIS Trial Group.

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Faecal calprotectin has been proposed as a sensitive marker for gastrointestinal inflammation in children and adults. High levels have been reported in healthy newborns and during the first months of life; the effect of the kind of feeding on the calprotectin concentration in stools is controversial. OBJECT...

journal_title：Neonatology

authors： Savino F,Castagno E,Calabrese R,Viola S,Oggero R,Miniero R

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:With the increasing incidence of births of very preterm very-low-birth-weight infants, there is a demand for echocardiographic reference values of cardiac dimensions. OBJECTIVES:The aim of this study was to provide reference values of cardiac valve annulus diameters in a cohort of extremely preterm very-low...

journal_title：Neonatology

authors： van Ark AE,Molenschot MC,Wesseling MH,de Vries WB,Strengers JLM,Adams A,Breur JMPJ

更新日期：2018-01-01 00:00:00