Adrenal function in preterm infants undergoing patent ductus arteriosus ligation.

abstract：BACKGROUND:Perinatal hypoxic-ischemic brain damage is a major cause of acute mortality and chronic neurological morbidity in infants and children. Oxidative stress due to free radical formation and the initiation of abnormal oxidative reactions appears to play a key role. Docosahexanoic acid (DHA), a main component of ...

journal_title：Neonatology

authors： Solberg R,Longini M,Proietti F,Perrone S,Felici C,Porta A,Saugstad OD,Buonocore G

更新日期：2017-01-01 00:00:00

abstract：:There is mounting evidence that early continuous positive airway pressure (CPAP) from birth is feasible and safe even in very preterm infants. However, many infants will develop respiratory distress syndrome (RDS) and require surfactant treatment. Combining a noninvasive ventilation approach with a strategy for surfac...

journal_title：Neonatology

authors： Blennow M,Bohlin K

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The identification of factors involved in the postnatal growth of preterm infants will help achieve growth similar to that of term infants. OBJECTIVES:As per protocol: to compare body composition in very preterm infants at term-corrected age (TCA) with that in term infants, and to explore relationships betw...

journal_title：Neonatology

authors： Tremblay G,Boudreau C,Bélanger S,St-Onge O,Pronovost E,Simonyan D,Marc I

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Fetal lung development requires proper coordination between lung epithelial and vascular morphogenesis. A major determinant in lung vascular development is vascular endothelial growth factor (VEGF), which is regulated by hypoxia-inducible factors (HIFs). VEGF is expressed in the airway epithelium, while its ...

journal_title：Neonatology

authors： Rajatapiti P,de Rooij JD,Beurskens LW,Keijzer R,Tibboel D,Rottier RJ,de Krijger RR

更新日期：2010-06-01 00:00:00

abstract：:Mechanical ventilation is a risk factor for cerebral inflammation and brain injury in preterm neonates. The risk increases proportionally with the intensity of treatment. Recent studies have shown that cerebral inflammation and injury can be initiated in the delivery room. At present, initiation of intermittent positi...

journal_title：Neonatology

authors： Barton SK,Tolcos M,Miller SL,Christoph-Roehr C,Schmölzer GM,Moss TJ,Hooper SB,Wallace EM,Polglase GR

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Intermittent hypoxic episodes are common among preterm infants, although longer term consequences on growth pattern and cardiovascular regulation are unclear. Furthermore, the effects of intermittent hypoxia (IH) may depend on the pattern of hypoxia-reoxygenation. OBJECTIVES:We tested the hypothesis that a ...

journal_title：Neonatology

authors： Pozo ME,Cave A,Köroğlu OA,Litvin DG,Martin RJ,Di Fiore J,Kc P

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:Lipid peroxidation products are present following oxidation of polyunsaturated fatty acids in the eye, brain, and various cell membranes. Elevated levels of lipid peroxidation products and increased intermittent hypoxemia (IH) events have been associated with adverse outcomes in extremely preterm infants. ...

journal_title：Neonatology

authors： Shah VP,Raffay TM,Martin RJ,Vento M,Sánchez-Illana Á,Piñeiro-Ramos JD,Kuligowski J,Di Fiore JM

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:In the absence of universal screening for congenital cytomegalovirus (cCMV) infection, the aim of this study was to assess the outcomes of a targeted screening protocol based on maternal and neonatal risk indicators. METHODS:The medical records of 2,623 neonates born in our maternal hospital between June 20...

journal_title：Neonatology

authors： Levit Y,Dym L,Yochpaz S,Manor Y,Adler A,Halutz O,Grisaru-Soen G,Herzlich J,Marom R

更新日期：2020-12-22 00:00:00

abstract：BACKGROUND:High-dose recombinant erythropoietin (rEpo) is neuroprotective in neonatal animal models of brain injury, but the long-term consequences of neonatal exposure have not been studied. OBJECTIVES:We hypothesized that multiple injections of high-dose rEpo during the neonatal period would be safe, and would impro...

journal_title：Neonatology

authors： McPherson RJ,Demers EJ,Juul SE

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Ventilatory pressures should target the range between the upper and lower inflection point of the pressure volume curve in order to avoid atelecto- and volutrauma. During high-frequency oscillatory ventilation (HFOV), this range is difficult to determine. Quadrant impedance measurement (QIM) has recently bee...

journal_title：Neonatology

authors： Burkhardt W,Kurth F,Pitterle M,Blassnig N,Wemhöner A,Rüdiger M

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Despite increasing survival in the smallest preterm infants, the incidence of chronic lung disease has not decreased. Research into ventilatory strategies has concentrated on minimising barotrauma, volutrauma and atelectotrauma, but little attention has been paid to the role of bias gas flow rates and the po...

journal_title：Neonatology

authors： Bach KP,Kuschel CA,Oliver MH,Bloomfield FH

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Refinement of ventilatory techniques remains a challenge given the persistence of chronic lung disease of preterm infants. METHODS:To test the hypothesis that proportional assist ventilation (PAV) will allow to lower the ventilator pressure at equivalent fractions of inspiratory oxygen (FiO(2)) and arterial...

journal_title：Neonatology

authors： Schulze A,Rieger-Fackeldey E,Gerhardt T,Claure N,Everett R,Bancalari E

更新日期：2007-01-01 00:00:00

abstract：:Bronchopulmonary dysplasia (BPD) is one of the few diseases in neonatal medicine that has continued to evolve since its first description about 50 years ago. Over these years, advancements in neonatal medicine such as antenatal steroids and exogenous surfactant therapy have significantly reduced neonatal mortality and...

journal_title：Neonatology

authors： Bancalari E,Jain D

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Oral propranolol has improved the treatment of infantile hemangiomas, and a pediatric oral solution of propranolol has recently been licensed in the USA and Europe. In very preterm infants, infantile hemangiomas are associated with the occurrence of retinopathy of prematurity (ROP), and both diseases share...

journal_title：Neonatology

authors： Bührer C,Bassler D

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Long-gap esophageal atresia (LGEA) may have clinical and syndromic presentations different from those of esophageal atresia (EA) that affects shorter segments of the esophagus (non-LGEA). This may suggest unique underlying developmental mechanisms. OBJECTIVES:We sought to characterize clinical differences b...

journal_title：Neonatology

authors： Bairdain S,Zurakowski D,Vargas SO,Stenquist N,McDonald M,Towne MC,Miller DT,Jennings RW,Kantor DB,Agrawal PB

更新日期：2017-01-01 00:00:00

abstract：:The aim of this article is to educate neonatal caregivers about metagenomics. This scientific field uses novel and ever changing molecular methods to identify how infants become colonized with microbes after birth. Publications using metagenomics appear infrequently in the neonatal literature because clinicians are un...

journal_title：Neonatology

authors： Sherman MP,Minnerly J,Curtiss W,Rangwala S,Kelley ST

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Recurrent and prolonged seizures are harmful for the developing brain, emphasizing the importance of early seizure recognition and effective therapy. Amplitude-integrated electroencephalography (aEEG) has become a valuable tool to diagnose epileptic seizures, and, in parallel, genetic etiologies are increasi...

journal_title：Neonatology

authors： Vilan A,Mendes Ribeiro J,Striano P,Weckhuysen S,Weeke LC,Brilstra E,de Vries LS,Cilio MR

更新日期：2017-01-01 00:00:00

abstract：:We describe three positive influenza AH1N1 cases in a neonatal unit during the influenza pandemic in Spain. One term baby presented with an upper respiratory tract infection, another preterm infant with an apnea episode following nosocomial infection, and thirdly, a term infant of a mother with influenza AH1N1 had sev...

journal_title：Neonatology

authors： Calvo C,Gonzalez-Carrasco E,Quevedo S,García-García ML,Rando A,Ledesma J,Calderon A,Pozo F,Pérez-Breña P,Casas I

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Meconium displaces surfactant from the alveolar surface and inhibits its function. The development of active synthetic surfactants is complicated, especially to synthesize the hydrophobic surfactant proteins SP-B and SP-C. A synthetic surfactant, CHF5633 containing SP-B and SP-C analogs, has been designed to...

journal_title：Neonatology

authors： Salvesen B,Curstedt T,Mollnes TE,Saugstad OD

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:International neonatal resuscitation guidelines recommend assessing chest excursion when the heart rate is not improving. However, the accuracy in assessing 'adequate' chest excursion lacks objectivity. AIM:It was the aim of this study to test the accuracy in the assessment of 'adequate' chest excursion by ...

journal_title：Neonatology

authors： Brugada M,Schilleman K,Witlox RS,Walther FJ,Vento M,Te Pas AB

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Preterm birth contributes significantly to infant mortality and morbidity, including blindness from retinopathy of prematurity (ROP). Access to intensive neonatal care is expanding in many countries, but care is not always optimal, one factor being that nursing is often by inadequately trained nurse assistan...

journal_title：Neonatology

authors： Gilbert C,Darlow B,Zin A,Sivasubramaniam S,Shah S,Gianini N,Beecroft G,Lopes Moreira ME

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Recently, sustained inflations (SI) during chest compression (CC) (CC+SI) have been suggested as an alternative to the current approach during neonatal resuscitation. No previous study compared CC+SI using CC rates of 90/min to the current 3:1 compression:ventilation ratio (C:V). OBJECTIVE:To determine whet...

journal_title：Neonatology

authors： Li ES,Görens I,Cheung PY,Lee TF,Lu M,O'Reilly M,Schmölzer GM

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Doxapram has been advocated as a treatment for persistent apnea of prematurity (AOP). OBJECTIVE:To evaluate the effect of doxapram on long-term neurodevelopmental outcome in preterm infants as its safety still needs to be established. METHODS:From a retrospective cohort of preterm infants with a gestationa...

journal_title：Neonatology

authors： Ten Hove CH,Vliegenthart RJ,Te Pas AB,Brouwer E,Rijken M,van Wassenaer-Leemhuis AG,van Kaam AH,Onland W

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Clinical illness caused by resistant bacteria usually represents a wider problem of asymptomatic colonization. Active surveillance with appropriate institution of isolation precautions represents a potential mechanism to control colonization and reduce infection. The neonatal intensive care unit (NICU) is an...

journal_title：Neonatology

authors： Benenson S,Levin PD,Block C,Adler A,Ergaz Z,Peleg O,Minster N,Gross I,Schaffer K,Moses AE,Cohen MJ

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:While hypoxic events with bradycardias are a frequent occurrence during the first weeks of life in preterm infants, the impact of preterm birth on maturation of the cardiovascular response to hypoxia in early postnatal life is unknown. OBJECTIVES:In the present study, we tested the hypothesis that preterm b...

journal_title：Neonatology

authors： Pladys P,Arsenault J,Reix P,Rouillard Lafond J,Moreau-Bussière F,Praud JP

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:Oxidative stress in the newborn period may cause cell injury and inflammation if the antioxidant capacity is insufficient. To monitor antioxidant and inflammatory activity we examined by in vivo imaging various strains of luciferase reporter mice whose light-emitting properties were regulated by response e...

journal_title：Neonatology

authors： Dohlen G,Odland HH,Carlsen H,Blomhoff R,Thaulow E,Saugstad OD

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Apnea of prematurity (AOP) occurs frequently in preterm infants and a variable proportion of AOP can be induced by gastroesophageal reflux (GER). Conservative treatment, including dietary modifications, should be the first-line approach for both GER and GER-related apneas in this population. OBJECTIVES:To e...

journal_title：Neonatology

authors： Corvaglia L,Spizzichino M,Aceti A,Legnani E,Mariani E,Martini S,Battistini B,Faldella G

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:No survey has been published in recent years which primarily focuses on the prescription of inhaled corticosteroids in neonatal practice. Thus, the utilization rate of inhaled corticosteroids is unknown. OBJECTIVES:To elucidate the current utilization rate of inhaled corticosteroids in the prevention and th...

journal_title：Neonatology

authors： Maas C,Poets CF,Bassler D

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Recent studies indicate an increasing use of less invasive surfactant administration. Different techniques have been shown with distinct risks and benefits. The aim of this study was to develop a new method that simplifies this procedure. OBJECTIVES:An applicator was developed and tested on a manikin to mak...

journal_title：Neonatology

authors： Maiwald CA,Neuberger P,Vochem M,Poets C

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Randomised controlled trials provide the best evidence for the effects of interventions and are a key tool in the effort to improve the care and outcomes for newborn infants. METHODS:We discuss the role of randomisation for minimising selection bias in clinical trials and describe examples of seminal trials...

journal_title：Neonatology

authors： Gale C,McGuire W,Juszczak E

更新日期：2020-01-01 00:00:00