QuickSF: A New Technique in Surfactant Administration.

abstract：OBJECTIVE:To examine the impact of medical complexity among very preterm infants on health care resource use, family, and neurodevelopmental outcomes at 18 months' corrected age. METHODS:This observational cohort study of Canadian infants born < 29 weeks' gestational age in 2009-2011 compared infants with and those wi...

journal_title：Neonatology

authors： Nassel D,Chartrand C,Doré-Bergeron MJ,Lefebvre F,Ballantyne M,Van Overmeire B,Luu TM,on behalf of the Canadian Neonatal Network and the Canadian Neonatal Follow-Up Network.

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Preventing the development of allergic skin disease in children is the best way to treat the disease. OBJECTIVES:Ultraviolet (UV)-free blue light phototherapy has been reported to treat atopic eczema. We evaluated the effect of neonatal phototherapy on allergic skin disease in children. METHODS:We randomly...

journal_title：Neonatology

authors： Ku MS

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Premature birth is a significant health care burden. Xenon (Xe) is a general anesthetic with neuroprotective effects. OBJECTIVES:Here, we investigate the neuroprotective role of Xe in a lipopolysaccharide (LPS)- and hypoxia-ischemia (HI)-induced white matter damage (WMD) model. METHODS:Three-day-old Spragu...

journal_title：Neonatology

authors： Yin X,Zhao J,Jiang H,Li L,Jiang J,Xi H,Peng X,Yin X,Shi X,Zhang L

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Inhaled glucocorticoids may increase the risk of pneumonia in adults. Thus, respiratory infections may be a potential explanation for the non-significantly increased mortality seen in the glucocorticoid group in the largest randomized trial on inhaled glucocorticoids for preventing bronchopulmonary dysplasia...

journal_title：Neonatology

authors： Koch A,Kreutzer K,von Oldershausen G,Poets CF,Bassler D,NEuroSIS Trial Group.

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Intermittent hypoxic episodes are common among preterm infants, although longer term consequences on growth pattern and cardiovascular regulation are unclear. Furthermore, the effects of intermittent hypoxia (IH) may depend on the pattern of hypoxia-reoxygenation. OBJECTIVES:We tested the hypothesis that a ...

journal_title：Neonatology

authors： Pozo ME,Cave A,Köroğlu OA,Litvin DG,Martin RJ,Di Fiore J,Kc P

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Meconium displaces surfactant from the alveolar surface and inhibits its function. The development of active synthetic surfactants is complicated, especially to synthesize the hydrophobic surfactant proteins SP-B and SP-C. A synthetic surfactant, CHF5633 containing SP-B and SP-C analogs, has been designed to...

journal_title：Neonatology

authors： Salvesen B,Curstedt T,Mollnes TE,Saugstad OD

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Sustained lung inflation (SLI) applied at birth has been demonstrated to lead to clearance of lung fluid and achievement of a precocious functional residual capacity in animal studies. OBJECTIVES:To verify if the application of SLI in preterm infants at birth may reduce the need for mechanical ventilation a...

journal_title：Neonatology

authors： Lista G,Fontana P,Castoldi F,Cavigioli F,Dani C

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a common enzyme deficiency affecting more than 300 million individuals worldwide. Extreme neonatal hyperbilirubinemia, with its severe sequelae of bilirubin neurotoxicity and the potential of death, is the most devastating manifestation of G6PD deficienc...

journal_title：Neonatology

authors： Kaplan M,Wong RJ,Stevenson DK

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Premature birth and respiratory distress syndrome (RDS) are risk factors for disturbed lung development and bronchopulmonary dysplasia (BPD). The molecular mechanisms related to prematurity and BPD remain largely unknown. Epithelial expression of the transcription factor GATA-6 has been implicated in normal ...

journal_title：Neonatology

authors： Vähätalo R,Asikainen TM,Karikoski R,Kinnula VL,White CW,Andersson S,Heikinheimo M,Myllärniemi M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Genetic processes underlying fetal lung development and maturation are incompletely understood. Better knowledge of these processes would provide insights into the causes of lung malformations and prevention of respiratory distress syndrome and the potential adverse effects of glucocorticoids. Hox genes are ...

journal_title：Neonatology

authors： Grier DG,Thompson A,Lappin TR,Halliday HL

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVES:Non-invasive cardiac output monitoring is a potentially useful clinical tool in the neonatal setting. Our aim was to evaluate a new method of non-invasive continuous cardiac output (CO) measurement (NICOM™) based on the principle of bioreactance in neonates. METHODS:In this prospective observational study, ...

journal_title：Neonatology

authors： Weisz DE,Jain A,McNamara PJ,EL-Khuffash A

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Minimizing initial neonatal blood draws and their associated pain is important. The placenta has ample fetal blood that is otherwise discarded; obtaining admission laboratory evaluations from fetal umbilical venous blood (FUVB) may provide a suitable alternative. OBJECTIVE:We hypothesized that obtaining an ...

journal_title：Neonatology

authors： Greer R,Safarulla A,Koeppel R,Aslam M,Bany-Mohammed FM

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Surface temperatures of fibreoptic phototherapy pads using a high intensity blue light-emitting diode (LED) light source have not been studied. OBJECTIVES:The aim of this study was to measure the temperature of LED fibreoptic phototherapy pads during phototherapy in a bench-top study, and to determine tempe...

journal_title：Neonatology

authors： Ng PL,Carlisle T,Ly M,Morris SA

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Premature infants with severe bronchopulmonary dysplasia (sBPD) are at risk of pulmonary hypertension (PH). Serum brain natriuretic peptide (BNP) is used to predict disease severity in adult PH. Its diagnostic utility in sBPD-associated PH is unknown. OBJECTIVE:The aim of this paper was to determine the acc...

journal_title：Neonatology

authors： Avitabile CM,Ansems S,Wang Y,Fraga MV,Kirpalani HM,Zhang H,Mercer-Rosa L,Jensen EA

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Targeted milrinone treatment for low left ventricular output (LVO) reduces the incidence of acute cardiorespiratory instability following ligation of patent ductus arteriosus (PDA) in preterm infants. Despite this, some infants continue to experience postoperative deterioration. Adrenal insufficiency related...

journal_title：Neonatology

authors： EL-Khuffash A,McNamara PJ,Lapointe A,Jain A

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Recent studies reported conflicting results on the relationship between antenatal magnesium sulfate (MgSO4) exposure and neonatal intestinal injury. Most studies have not assessed MgSO4 exposure quantitatively and none reported the exposure timing. OBJECTIVES:The aim of this work was to assess whether there...

journal_title：Neonatology

authors： Mikhael M,Bronson C,Zhang L,Curran M,Rodriguez H,Bhakta KY

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Preterm infants with signs of poor perfusion are often treated with volume expansion, although evidence regarding its effect on cerebral perfusion is lacking. Moreover, the effect is questionable in preterm infants with an adequate cerebrovascular autoregulation (CAR). A useful measure to assess perfusion is...

journal_title：Neonatology

authors： Kooi EM,van der Laan ME,Verhagen EA,Van Braeckel KN,Bos AF

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Umbilical arterial catheters (UACs) are frequently used in critically ill neonates. UAC are convenient, reliable, and allow for caregiver convenience in performing painless arterial blood sampling. We hypothesized that UAC removal in extremely low birth weight (ELBW) neonates will result in significantly les...

journal_title：Neonatology

authors： Carroll PD,Zimmerman MB,Nalbant D,Gingerich EL,An G,Cress GA,Veng-Pedersen P,Widness JA

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Newborns are susceptible to inflammatory diseases due to defects in clearing activated immune cells from tissues. Therefore, mechanisms have likely evolved to protect neonates from leukocyte-mediated cytotoxicity. Bilirubin has antioxidant activity, and it is possible that it also exerts effects on cellular ...

journal_title：Neonatology

authors： Weinberger B,Archer FE,Kathiravan S,Hirsch DS,Kleinfeld AM,Vetrano AM,Hegyi T

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:We hypothesized that color Doppler-measured cerebral blood flow velocity (CD-CBFV) as measured in the three feeding arteries of the brain can be used as an estimator of global cerebral blood flow. PATIENTS AND METHODS:CD-CBFV was determined as soon as possible after determination of phase-contrast magnetic ...

journal_title：Neonatology

authors： Benders MJ,Hendrikse J,de Vries L,Groenendaal F,van Bel F

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Cardiac troponin T (cTnT) has been proposed as specific biochemical marker for myocardial infarction in adults. Cardiac function in neonates could be influenced by the severity of respiratory distress and its ventilatory management. OBJECTIVES:To establish a normal range of cTnT in healthy neonates, compare...

journal_title：Neonatology

authors： Awada H,Al-Tannir M,Ziade MF,Alameh J,El Rajab M

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Transcutaneous bilirubin (TcB) devices are commonly used for screening of hyperbilirubinemia in term and near-term infants not exposed to phototherapy. However, the accuracy of TcB devices in infants exposed to phototherapy is unclear. OBJECTIVES:To conduct a systematic review of studies comparing TcB devic...

journal_title：Neonatology

authors： Nagar G,Vandermeer B,Campbell S,Kumar M

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Apnea of prematurity (AOP) occurs frequently in preterm infants and a variable proportion of AOP can be induced by gastroesophageal reflux (GER). Conservative treatment, including dietary modifications, should be the first-line approach for both GER and GER-related apneas in this population. OBJECTIVES:To e...

journal_title：Neonatology

authors： Corvaglia L,Spizzichino M,Aceti A,Legnani E,Mariani E,Martini S,Battistini B,Faldella G

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Clinical illness caused by resistant bacteria usually represents a wider problem of asymptomatic colonization. Active surveillance with appropriate institution of isolation precautions represents a potential mechanism to control colonization and reduce infection. The neonatal intensive care unit (NICU) is an...

journal_title：Neonatology

authors： Benenson S,Levin PD,Block C,Adler A,Ergaz Z,Peleg O,Minster N,Gross I,Schaffer K,Moses AE,Cohen MJ

更新日期：2013-01-01 00:00:00

abstract：:Treatment of sick neonates originated in maternity and foundling hospitals in the 19th century. Nosocomial infections and difficult logistics of wet-nursing prevented admission of neonates in most children's hospitals well into the 20th century. In this article, 31 hospitals are described, all located in large cities,...

journal_title：Neonatology

authors： Obladen M

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Endogenous carbon monoxide (CO) production is primarily due to heme degradation, which also results in the equimolar production of bilirubin. Thus, estimates of total body CO production can serve as indices of total body bilirubin formation. The elimination rate of CO from a person's body (CO washout rate) a...

journal_title：Neonatology

authors： Stevenson DK,Wong RJ,Ostrander CR,Maric I,Vreman HJ,Cohen RS

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Various studies have shown an association between low birth weight and the prevalence of elevated blood pressure later in life. However, a relationship between birth weight and blood pressure in the neonatal period has not been investigated yet. OBJECTIVE:To study the relationship between birth weight and b...

journal_title：Neonatology

authors： Smal JC,Uiterwaal CS,Bruinse HW,Steendijk P,van Bel F

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Fetal lung development requires proper coordination between lung epithelial and vascular morphogenesis. A major determinant in lung vascular development is vascular endothelial growth factor (VEGF), which is regulated by hypoxia-inducible factors (HIFs). VEGF is expressed in the airway epithelium, while its ...

journal_title：Neonatology

authors： Rajatapiti P,de Rooij JD,Beurskens LW,Keijzer R,Tibboel D,Rottier RJ,de Krijger RR

更新日期：2010-06-01 00:00:00

abstract：:We report the successful and safe use of levosimendan, a new calcium-sensitizing agent with positive inotropic and vasodilatory action, in 2 critically ill term newborns with acute heart failure and pulmonary hypertension in the absence of any underlying heart malformation and/or previous cardiosurgical procedures. Du...

journal_title：Neonatology

authors： De Carolis MP,Piastra M,Bersani I,Pardeo M,Stival E,Tempera A,Romagnoli C,Conti G,De Rosa G

更新日期：2012-01-01 00:00:00

abstract：:We describe three positive influenza AH1N1 cases in a neonatal unit during the influenza pandemic in Spain. One term baby presented with an upper respiratory tract infection, another preterm infant with an apnea episode following nosocomial infection, and thirdly, a term infant of a mother with influenza AH1N1 had sev...

journal_title：Neonatology

authors： Calvo C,Gonzalez-Carrasco E,Quevedo S,García-García ML,Rando A,Ledesma J,Calderon A,Pozo F,Pérez-Breña P,Casas I

更新日期：2011-01-01 00:00:00