Abstract:
BACKGROUND:Heart rate (HR) detection in premature infants using electrocardiography (ECG) is challenging due to a low signal amplitude and the fragility of the premature skin. Recently, the dynamic light scattering (DLS) technique has been miniaturized, allowing noninvasive HR measurements with a single sensor. OBJECTIVE:The aim was to determine the accuracy of DLS for HR measurement in infants, compared to ECG-derived HR. METHODS:Stable infants with a gestational age of ≥26 weeks, monitored with ECG, were eligible for inclusion. HR was measured with the DLS sensor at 5 different sites for 15 min each. We recorded every 10th second of the DLS-derived HR and the DLS signal-to-noise ratio (SNR), and the ECG-derived HR was extracted for analysis. Patients were randomly divided into 2 groups. In the first group, the optimal SNR cut-off value was determined and then applied to the second group to assess agreement. RESULTS:HR measurements from 31 infants were analyzed. ECG-DLS paired data points were collected at the forehead, an upper extremity, the thorax, a lower extremity, and the abdomen. When applying the international accuracy standard for HR detection, DLS accuracy in the first group (n = 15) was optimal at the forehead (SNR cut-off 1.66). Application of this cut-off to the second group (n = 16) showed good agreement between DLS-derived HR and ECG-derived HR (bias -0.73 bpm; 95% limits of agreement -15.46 and 14.00 bpm) at the forehead with approximately 80% (i.e., 1,066/1,310) of all data pairs remaining. CONCLUSION:The investigated DLS sensor was sensitive to movement, overall providing less accurate HR measurements than ECG and pulse oximetry. In this study population, specific measurement sites provided excellent signal quality and good agreement with ECG-derived HR.
journal_name
Neonatologyjournal_title
Neonatologyauthors
Gangaram-Panday NH,van Essen T,Goos TG,de Jonge RCJ,Reiss IKM,van Weteringen Wdoi
10.1159/000506771subject
Has Abstractpub_date
2020-01-01 00:00:00pages
279-286issue
3eissn
1661-7800issn
1661-7819pii
000506771journal_volume
117pub_type
杂志文章相关文献
Neonatology文献大全abstract:INTRODUCTION:Cerebellar injury is increasingly recognized as a relevant complication of premature birth. However, the prevalence of reduced cerebellar growth and its consequences for neurodevelopmental outcome in preterm infants without overt brain injury remain to be defined in detail. The aim of this study was to ass...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000502491
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Faecal calprotectin has been proposed as a sensitive marker for gastrointestinal inflammation in children and adults. High levels have been reported in healthy newborns and during the first months of life; the effect of the kind of feeding on the calprotectin concentration in stools is controversial. OBJECT...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000255161
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:Preventing the development of allergic skin disease in children is the best way to treat the disease. OBJECTIVES:Ultraviolet (UV)-free blue light phototherapy has been reported to treat atopic eczema. We evaluated the effect of neonatal phototherapy on allergic skin disease in children. METHODS:We randomly...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000489389
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Closed endotracheal suction interferes with mechanical ventilation received by infants, but the change to ventilation may be different when ventilator modes that target expired tidal volume (VT(e)) are used. OBJECTIVE:To measure airway pressure and tidal volume distal to the endotracheal tube (ETT) during a...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000316854
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Congenital diaphragmatic hernia (CDH) is an abnormal development of the diaphragm leading to high neonatal mortality and morbidity. Beyond the neonatal period, prospective data on overall long-term outcome in CDH survivors is scarce. In particular, for those treated with fetoscopic endoluminal tracheal occlu...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000479145
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Preterm birth contributes significantly to infant mortality and morbidity, including blindness from retinopathy of prematurity (ROP). Access to intensive neonatal care is expanding in many countries, but care is not always optimal, one factor being that nursing is often by inadequately trained nurse assistan...
journal_title:Neonatology
pub_type: 临床试验,杂志文章
doi:10.1159/000362532
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Early host-microbe interaction provides important maturational stimuli for the developing immune system. The role of prenatal microbial contact remains elusive. OBJECTIVES:Our aim was to investigate whether microbes in placenta or amniotic fluid affect fetal innate immune gene expression during late pregnan...
journal_title:Neonatology
pub_type: 杂志文章,随机对照试验
doi:10.1159/000339182
更新日期:2012-01-01 00:00:00
abstract::We report the successful and safe use of levosimendan, a new calcium-sensitizing agent with positive inotropic and vasodilatory action, in 2 critically ill term newborns with acute heart failure and pulmonary hypertension in the absence of any underlying heart malformation and/or previous cardiosurgical procedures. Du...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000329848
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Lipid metabolism is vital to fetal development and cardiometabolic health and the final weeks of gestation are known to be a time of intense metabolic activity. New techniques such as lipidomics allow investigation of a complex lipidomic profile in infants. OBJECTIVES:This research aimed to (1) describe var...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000487506
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Corticosteroids have been used widely after birth in preterm infants with respiratory failure; hydrocortisone may be preferable to other corticosteroids for this purpose. OBJECTIVES:To determine if postnatal hydrocortisone is useful to prevent or treat bronchopulmonary dysplasia (BPD) in preterm infants. M...
journal_title:Neonatology
pub_type: 杂志文章,meta分析,评审
doi:10.1159/000279992
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Targeted milrinone treatment for low left ventricular output (LVO) reduces the incidence of acute cardiorespiratory instability following ligation of patent ductus arteriosus (PDA) in preterm infants. Despite this, some infants continue to experience postoperative deterioration. Adrenal insufficiency related...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000350017
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Fetal lung development requires proper coordination between lung epithelial and vascular morphogenesis. A major determinant in lung vascular development is vascular endothelial growth factor (VEGF), which is regulated by hypoxia-inducible factors (HIFs). VEGF is expressed in the airway epithelium, while its ...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000261018
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:Cardiac troponin T (cTnT) has been proposed as specific biochemical marker for myocardial infarction in adults. Cardiac function in neonates could be influenced by the severity of respiratory distress and its ventilatory management. OBJECTIVES:To establish a normal range of cTnT in healthy neonates, compare...
journal_title:Neonatology
pub_type: 临床试验,杂志文章
doi:10.1159/000100964
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Gene expression profiling of the salivary supernatant is emerging as a new and important source of real-time, systemic, biological information. However, existing technologies prevent RNA extraction of small quantities found in neonatal salivary supernatant. OBJECTIVE:The aim of this study was to develop tec...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000328026
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Neonatal reference values of gallbladder size have been assessed in healthy newborns with enteral feeding regimen. Their applicability to critically ill patients under total parenteral nutrition (TPN) remains to be questioned. OBJECTIVE:Our aim was to evaluate the impact of short-term TPN versus enteral nut...
journal_title:Neonatology
pub_type: 临床试验,杂志文章
doi:10.1159/000102058
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:The postnatal heart responds to biomechanical stress with hypertrophy. The fetal heart may also undergo hyperplasia, but the percentage of mitotically active cardiomyocytes decreases throughout gestation. The signaling pathways controlling growth and proliferation in the fetal heart are poorly understood. O...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000107729
更新日期:2008-01-01 00:00:00
abstract::Ductus arteriosus and foramen ovale were described by Galen without understanding their functions. His beliefs in soul localization and spiritization within the left ventricle established religious pneumatology which became a theological need in the Middle Ages. Pulmonary transit was recognized by Servetus and Colombo...
journal_title:Neonatology
pub_type: 历史文章,杂志文章
doi:10.1159/000308367
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Retinopathy of prematurity (ROP) is a sight-threatening disease affecting extremely preterm infants. The introduction of new ROP screening surveillance systems, with higher sensitivity and specificity than established ROP screening guidelines, has the potential to reduce the number of stressful eye examinati...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000435770
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Intermittent hypoxic episodes are common among preterm infants, although longer term consequences on growth pattern and cardiovascular regulation are unclear. Furthermore, the effects of intermittent hypoxia (IH) may depend on the pattern of hypoxia-reoxygenation. OBJECTIVES:We tested the hypothesis that a ...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000338096
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVES:To compare the ultrasound examination with pH-metry in order to evaluate the diagnostic accuracy of sonography for diagnosis of gastro-oesophageal reflux (GOR) in preterm infants. METHODS:A prospective study was conducted on 31 premature infants <34 weeks with clinically diagnosed GOR. First, they underwent...
journal_title:Neonatology
pub_type: 临床试验,杂志文章
doi:10.1159/000097447
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVES:Non-invasive cardiac output monitoring is a potentially useful clinical tool in the neonatal setting. Our aim was to evaluate a new method of non-invasive continuous cardiac output (CO) measurement (NICOM™) based on the principle of bioreactance in neonates. METHODS:In this prospective observational study, ...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000337295
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Recently, sustained inflations (SI) during chest compression (CC) (CC+SI) have been suggested as an alternative to the current approach during neonatal resuscitation. No previous study compared CC+SI using CC rates of 90/min to the current 3:1 compression:ventilation ratio (C:V). OBJECTIVE:To determine whet...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000477998
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Retinopathy of prematurity (ROP) is a gestational age (GA)-related illness that can lead to blindness in premature infants. Timely screening of premature infants could improve visual prognosis. OBJECTIVE:To evaluate the WINROP algorithm as a method of predicting severe ROP in a Chinese population. METHODS:...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000351297
更新日期:2013-01-01 00:00:00
abstract::Noninvasive ventilation for preterm infants at birth has been recommended and universally adopted. The umbilical cord is often clamped immediately in order to provide the support the infant needs for stabilization. However, recent scientific data from experimental studies that involve animals in transition and human s...
journal_title:Neonatology
pub_type: 杂志文章,评审
doi:10.1159/000497421
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Refinement of ventilatory techniques remains a challenge given the persistence of chronic lung disease of preterm infants. METHODS:To test the hypothesis that proportional assist ventilation (PAV) will allow to lower the ventilator pressure at equivalent fractions of inspiratory oxygen (FiO(2)) and arterial...
journal_title:Neonatology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1159/000098376
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Newborns are prone to infections, which are independent predictors of neonatal mortality and morbidity. Neutrophil extracellular traps (NETs) are structures composed of chromatin and antimicrobial molecules that capture and kill pathogens. NETs may play an important role in the innate immune system and, thus...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000452615
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:The identification of factors involved in the postnatal growth of preterm infants will help achieve growth similar to that of term infants. OBJECTIVES:As per protocol: to compare body composition in very preterm infants at term-corrected age (TCA) with that in term infants, and to explore relationships betw...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000450882
更新日期:2017-01-01 00:00:00
abstract::There is mounting evidence that early continuous positive airway pressure (CPAP) from birth is feasible and safe even in very preterm infants. However, many infants will develop respiratory distress syndrome (RDS) and require surfactant treatment. Combining a noninvasive ventilation approach with a strategy for surfac...
journal_title:Neonatology
pub_type: 杂志文章,评审
doi:10.1159/000381122
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:To examine the impact of medical complexity among very preterm infants on health care resource use, family, and neurodevelopmental outcomes at 18 months' corrected age. METHODS:This observational cohort study of Canadian infants born < 29 weeks' gestational age in 2009-2011 compared infants with and those wi...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000496494
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:The incidence of adverse tracheal intubation-associated events (TIAEs) and associated patient, practice, and intubator characteristics in the neonatal intensive care unit (NICU) setting are unknown. OBJECTIVES:To determine the incidence of adverse TIAEs and to identify factors associated with TIAEs in the N...
journal_title:Neonatology
pub_type: 杂志文章
doi:10.1159/000381252
更新日期:2015-01-01 00:00:00