Impact of Xenon on CLIC4 and Bcl-2 Expression in Lipopolysaccharide and Hypoxia-Ischemia-Induced Periventricular White Matter Damage.

abstract：BACKGROUND:High-dose recombinant erythropoietin (rEpo) is neuroprotective in neonatal animal models of brain injury, but the long-term consequences of neonatal exposure have not been studied. OBJECTIVES:We hypothesized that multiple injections of high-dose rEpo during the neonatal period would be safe, and would impro...

journal_title：Neonatology

authors： McPherson RJ,Demers EJ,Juul SE

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Long-gap esophageal atresia (LGEA) may have clinical and syndromic presentations different from those of esophageal atresia (EA) that affects shorter segments of the esophagus (non-LGEA). This may suggest unique underlying developmental mechanisms. OBJECTIVES:We sought to characterize clinical differences b...

journal_title：Neonatology

authors： Bairdain S,Zurakowski D,Vargas SO,Stenquist N,McDonald M,Towne MC,Miller DT,Jennings RW,Kantor DB,Agrawal PB

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Caffeine is a commonly used drug for apnea of prematurity. It may, however, also have a beneficial effect on bronchopulmonary dysplasia (BPD), which is the most common complication of extreme preterm birth. OBJECTIVES:To study the inflammatory, structural and functional effects of caffeine in an animal mode...

journal_title：Neonatology

authors： Nagatomo T,Jiménez J,Richter J,De Baere S,Vanoirbeek J,Naulaers G,Allegaert K,Croubels S,Deprest JA,Toelen J

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Recent studies indicate an increasing use of less invasive surfactant administration. Different techniques have been shown with distinct risks and benefits. The aim of this study was to develop a new method that simplifies this procedure. OBJECTIVES:An applicator was developed and tested on a manikin to mak...

journal_title：Neonatology

authors： Maiwald CA,Neuberger P,Vochem M,Poets C

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Endogenous carbon monoxide (CO) production is primarily due to heme degradation, which also results in the equimolar production of bilirubin. Thus, estimates of total body CO production can serve as indices of total body bilirubin formation. The elimination rate of CO from a person's body (CO washout rate) a...

journal_title：Neonatology

authors： Stevenson DK,Wong RJ,Ostrander CR,Maric I,Vreman HJ,Cohen RS

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Nosocomial infections endanger preterm infants. OBJECTIVE:The aim of the present controlled randomized trial was to investigate whether Bifidobacterium lactis reduces the incidence of nosocomial infections in infants with very low birth weight (VLBW; <1,500 g) <30 weeks of gestation. PATIENTS AND METHODS:I...

journal_title：Neonatology

authors： Mihatsch WA,Vossbeck S,Eikmanns B,Hoegel J,Pohlandt F

更新日期：2010-01-01 00:00:00

abstract：:Rites of passage mark important changes during human life and, for the neonate, its transition from intrauterine life into society. Their original intent was to purify the body from blood and meconium. But the cleansing rites had a spiritual dimension from the very start. When the rites of Mesopotamian, Egyptian, Jewi...

journal_title：Neonatology

authors： Obladen M

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Pharmacological closure of patent ductus arteriosus (PDA) is commonly achieved by intravenous (IV) administration of ibuprofen or indomethacin. Occasionally, oral ibuprofen is used for PDA treatment although its efficacy and safety are unclear. OBJECTIVES:To systematically review randomized and quasi-random...

journal_title：Neonatology

authors： Neumann R,Schulzke SM,Bührer C

更新日期：2012-01-01 00:00:00

abstract：:The treatment of preterm newborn rabbits with synthetic surfactants containing simple phospholipid mixtures and peptides gives similar tidal volumes to treatment with poractant alfa (Curosurf®). The addition of both surfactant protein B and C analogs to the phospholipid mixture will stabilize the alveoli, measured as ...

journal_title：Neonatology

authors： Curstedt T,Calkovska A,Johansson J

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a common enzyme deficiency affecting more than 300 million individuals worldwide. Extreme neonatal hyperbilirubinemia, with its severe sequelae of bilirubin neurotoxicity and the potential of death, is the most devastating manifestation of G6PD deficienc...

journal_title：Neonatology

authors： Kaplan M,Wong RJ,Stevenson DK

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Recurrent and prolonged seizures are harmful for the developing brain, emphasizing the importance of early seizure recognition and effective therapy. Amplitude-integrated electroencephalography (aEEG) has become a valuable tool to diagnose epileptic seizures, and, in parallel, genetic etiologies are increasi...

journal_title：Neonatology

authors： Vilan A,Mendes Ribeiro J,Striano P,Weckhuysen S,Weeke LC,Brilstra E,de Vries LS,Cilio MR

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Phenobarbital and midazolam are commonly used drugs in (near-)term neonates treated with therapeutic hypothermia for hypoxic-ischaemic encephalopathy, for sedation, and/or as anti-epileptic drug. Phenobarbital is an inducer of cytochrome P450 (CYP) 3A, while midazolam is a CYP3A substrate. Therefore, co-trea...

journal_title：Neonatology

authors： Favié LMA,Groenendaal F,van den Broek MPH,Rademaker CMA,de Haan TR,van Straaten HLM,Dijk PH,van Heijst A,Simons SHP,Dijkman KP,Rijken M,Zonnenberg IA,Cools F,Zecic A,van der Lee JH,Nuytemans DHGM,van Bel F,Egberts TCG,

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Around 10% of newborn infants require assistance during transition after birth. Heart rate (HR) is the most important clinical indicator to evaluate the clinical status of a newborn. AIM:Our study aimed to review all established and novel methods to detect HR in babies giving special consideration to non-in...

journal_title：Neonatology

authors： Anton O,Fernandez R,Rendon-Morales E,Aviles-Espinosa R,Jordan H,Rabe H

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Phenobarbitone induces suppression of cerebral electrical activity on amplitude-integrated electroencephalography (aEEG) in neonates with hypoxic-ischemic encephalopathy (HIE); however, its effect during therapeutic hypothermia (TH) has not been well characterized. OBJECTIVE:To evaluate the effect of phenob...

journal_title：Neonatology

authors： Deshpande P,Jain A,McNamara PJ

更新日期：2021-01-07 00:00:00

abstract：INTRODUCTION:Oxidative stress in the newborn period may cause cell injury and inflammation if the antioxidant capacity is insufficient. To monitor antioxidant and inflammatory activity we examined by in vivo imaging various strains of luciferase reporter mice whose light-emitting properties were regulated by response e...

journal_title：Neonatology

authors： Dohlen G,Odland HH,Carlsen H,Blomhoff R,Thaulow E,Saugstad OD

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:International neonatal resuscitation guidelines recommend assessing chest excursion when the heart rate is not improving. However, the accuracy in assessing 'adequate' chest excursion lacks objectivity. AIM:It was the aim of this study to test the accuracy in the assessment of 'adequate' chest excursion by ...

journal_title：Neonatology

authors： Brugada M,Schilleman K,Witlox RS,Walther FJ,Vento M,Te Pas AB

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Apnea of prematurity (AOP) occurs frequently in preterm infants and a variable proportion of AOP can be induced by gastroesophageal reflux (GER). Conservative treatment, including dietary modifications, should be the first-line approach for both GER and GER-related apneas in this population. OBJECTIVES:To e...

journal_title：Neonatology

authors： Corvaglia L,Spizzichino M,Aceti A,Legnani E,Mariani E,Martini S,Battistini B,Faldella G

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:Cerebellar injury is increasingly recognized as a relevant complication of premature birth. However, the prevalence of reduced cerebellar growth and its consequences for neurodevelopmental outcome in preterm infants without overt brain injury remain to be defined in detail. The aim of this study was to ass...

journal_title：Neonatology

authors： Hammerl M,Zagler M,Griesmaier E,Janjic T,Gizewski ER,Kiechl-Kohlendorfer U,Neubauer V

更新日期：2020-01-01 00:00:00

abstract：AIM:To determine the prevalence of renal anomalies in patients with an isolated single umbilical artery (SUA). METHODS:We performed a retrospective study of all renal ultrasound examinations assessed at our centre between January 1998 and December 2008 in neonates with SUA with or without associated anomalies. RESULT...

journal_title：Neonatology

authors： de Boom ML,Kist-van Holthe JE,Sramek A,Lardenoye SW,Walther FJ,Lopriore E

更新日期：2010-01-01 00:00:00

abstract：:We report the successful and safe use of levosimendan, a new calcium-sensitizing agent with positive inotropic and vasodilatory action, in 2 critically ill term newborns with acute heart failure and pulmonary hypertension in the absence of any underlying heart malformation and/or previous cardiosurgical procedures. Du...

journal_title：Neonatology

authors： De Carolis MP,Piastra M,Bersani I,Pardeo M,Stival E,Tempera A,Romagnoli C,Conti G,De Rosa G

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Recent studies reported conflicting results on the relationship between antenatal magnesium sulfate (MgSO4) exposure and neonatal intestinal injury. Most studies have not assessed MgSO4 exposure quantitatively and none reported the exposure timing. OBJECTIVES:The aim of this work was to assess whether there...

journal_title：Neonatology

authors： Mikhael M,Bronson C,Zhang L,Curran M,Rodriguez H,Bhakta KY

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:We hypothesized that color Doppler-measured cerebral blood flow velocity (CD-CBFV) as measured in the three feeding arteries of the brain can be used as an estimator of global cerebral blood flow. PATIENTS AND METHODS:CD-CBFV was determined as soon as possible after determination of phase-contrast magnetic ...

journal_title：Neonatology

authors： Benders MJ,Hendrikse J,de Vries L,Groenendaal F,van Bel F

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Ventilatory pressures should target the range between the upper and lower inflection point of the pressure volume curve in order to avoid atelecto- and volutrauma. During high-frequency oscillatory ventilation (HFOV), this range is difficult to determine. Quadrant impedance measurement (QIM) has recently bee...

journal_title：Neonatology

authors： Burkhardt W,Kurth F,Pitterle M,Blassnig N,Wemhöner A,Rüdiger M

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:No survey has been published in recent years which primarily focuses on the prescription of inhaled corticosteroids in neonatal practice. Thus, the utilization rate of inhaled corticosteroids is unknown. OBJECTIVES:To elucidate the current utilization rate of inhaled corticosteroids in the prevention and th...

journal_title：Neonatology

authors： Maas C,Poets CF,Bassler D

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Streptococcus agalactiae (group B Streptococcus, GBS) is the most common cause of early neonatal infection, but restricting the diagnosis to culture-positive infants may underestimate the burden of GBS disease. Our objective was to determine whether maternal GBS colonization was associated with an increased ...

journal_title：Neonatology

authors： Brigtsen AK,Jacobsen AF,Dedi L,Melby KK,Fugelseth D,Whitelaw A

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Randomised controlled trials provide the best evidence for the effects of interventions and are a key tool in the effort to improve the care and outcomes for newborn infants. METHODS:We discuss the role of randomisation for minimising selection bias in clinical trials and describe examples of seminal trials...

journal_title：Neonatology

authors： Gale C,McGuire W,Juszczak E

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Hypoxia-ischemia (HI) results in increased activation of Ca2+/calmodulin kinase IV (CaM kinase IV) mediated by Src kinase. Therapeutic hypothermia ameliorates neuronal injury in the newborn. HYPOTHESIS:Inhibition of Src kinase concurrently with hypothermia further attenuates the hypoxia-induced increased ac...

journal_title：Neonatology

authors： Kratimenos P,Koutroulis I,Jain A,Malaeb S,Delivoria-Papadopoulos M

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Premature infants with severe bronchopulmonary dysplasia (sBPD) are at risk of pulmonary hypertension (PH). Serum brain natriuretic peptide (BNP) is used to predict disease severity in adult PH. Its diagnostic utility in sBPD-associated PH is unknown. OBJECTIVE:The aim of this paper was to determine the acc...

journal_title：Neonatology

authors： Avitabile CM,Ansems S,Wang Y,Fraga MV,Kirpalani HM,Zhang H,Mercer-Rosa L,Jensen EA

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Carriers of Staphylococcus aureus strains can be the source of epidemic infection for patients. OBJECTIVES:A molecular epidemiological analysis of an impetigo bullosa outbreak in a neonatal ward was performed in order to determine a potential source of the infection and possible routes of subsequent spreadi...

journal_title：Neonatology

authors： Jursa-Kulesza J,Kordek A,Kopron K,Wojciuk B,Giedrys-Kalemba S

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Bronchopulmonary dysplasia (BPD), severe retinopathy of prematurity (sROP), and cystic periventricular leukomalacia (cPVL) are 3 major morbidities with long-term neurodevelopmental impairments in preterm infants. OBJECTIVE:To investigate the strength of associations and identify key risk factors shared by B...

journal_title：Neonatology

authors： Wang LW,Lin YC,Wang ST,Huang CC,on behalf of the Taiwan Premature Infant Developmental Collaborative Study Group.

更新日期：2018-01-01 00:00:00