Hemolysis and Glucose-6-Phosphate Dehydrogenase Deficiency-Related Neonatal Hyperbilirubinemia.

abstract：BACKGROUND:Long-gap esophageal atresia (LGEA) may have clinical and syndromic presentations different from those of esophageal atresia (EA) that affects shorter segments of the esophagus (non-LGEA). This may suggest unique underlying developmental mechanisms. OBJECTIVES:We sought to characterize clinical differences b...

journal_title：Neonatology

authors： Bairdain S,Zurakowski D,Vargas SO,Stenquist N,McDonald M,Towne MC,Miller DT,Jennings RW,Kantor DB,Agrawal PB

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Numerous studies in cultured cells indicate that damage to mitochondrial DNA (mtDNA) dictates cellular responses to oxidant stress, yet the consequences of mtDNA damage have not been studied directly in the preterm lung. OBJECTIVE:We sought to determine whether hyperoxia-induced fetal lung dysmorphogenesis ...

journal_title：Neonatology

authors： Gebb SA,Decoux A,Waggoner A,Wilson GL,Gillespie MN

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Preterm infants are at greater risk of developmental impairment and require close follow-up for early and optimal care. OBJECTIVES:The objective of the present study was to determine from which age the parental Ages and Stages Questionnaire (ASQ) allows detection of school difficulties in preterm children <...

journal_title：Neonatology

authors： Halbwachs M,Muller JB,Nguyen The Tich S,Gascoin G,Chauty-Frondas A,Branger B,Rouger V,Roze JC,Flamant C

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Doxapram has been advocated as a treatment for persistent apnea of prematurity (AOP). OBJECTIVE:To evaluate the effect of doxapram on long-term neurodevelopmental outcome in preterm infants as its safety still needs to be established. METHODS:From a retrospective cohort of preterm infants with a gestationa...

journal_title：Neonatology

authors： Ten Hove CH,Vliegenthart RJ,Te Pas AB,Brouwer E,Rijken M,van Wassenaer-Leemhuis AG,van Kaam AH,Onland W

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Serum ferritin measurements are used in clinical populations to estimate total body iron stores and the risk of subsequent iron deficiency or overload. The lack of normative newborn serum ferritin concentration data between 23 and 41 weeks has led to difficulty in establishing the incidence and degree of abn...

journal_title：Neonatology

authors： Siddappa AM,Rao R,Long JD,Widness JA,Georgieff MK

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Transcutaneous bilirubin (TcB) devices are commonly used for screening of hyperbilirubinemia in term and near-term infants not exposed to phototherapy. However, the accuracy of TcB devices in infants exposed to phototherapy is unclear. OBJECTIVES:To conduct a systematic review of studies comparing TcB devic...

journal_title：Neonatology

authors： Nagar G,Vandermeer B,Campbell S,Kumar M

更新日期：2016-01-01 00:00:00

abstract：:Bronchopulmonary dysplasia (BPD) is one of the few diseases in neonatal medicine that has continued to evolve since its first description about 50 years ago. Over these years, advancements in neonatal medicine such as antenatal steroids and exogenous surfactant therapy have significantly reduced neonatal mortality and...

journal_title：Neonatology

authors： Bancalari E,Jain D

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Lipid metabolism is vital to fetal development and cardiometabolic health and the final weeks of gestation are known to be a time of intense metabolic activity. New techniques such as lipidomics allow investigation of a complex lipidomic profile in infants. OBJECTIVES:This research aimed to (1) describe var...

journal_title：Neonatology

authors： McCloskey K,De Livera AM,Collier F,Ponsonby AL,Carlin JB,Vuillermin P,Mellett NA,Jayawardana K,Weir JM,Blangero J,Curran JE,Burgner D,Meikle PJ,BIS investigator group.

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Preventing the development of allergic skin disease in children is the best way to treat the disease. OBJECTIVES:Ultraviolet (UV)-free blue light phototherapy has been reported to treat atopic eczema. We evaluated the effect of neonatal phototherapy on allergic skin disease in children. METHODS:We randomly...

journal_title：Neonatology

authors： Ku MS

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Faecal calprotectin has been proposed as a sensitive marker for gastrointestinal inflammation in children and adults. High levels have been reported in healthy newborns and during the first months of life; the effect of the kind of feeding on the calprotectin concentration in stools is controversial. OBJECT...

journal_title：Neonatology

authors： Savino F,Castagno E,Calabrese R,Viola S,Oggero R,Miniero R

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Inflammation due to perinatal infection (PI) and perinatal asphyxia (PA) may cause damage to various tissues and very often to the immature brain of the fetus and the newborn. Previously, we have shown that the neonatal immune system has the ability to produce increased chemokine protein levels in the serum ...

journal_title：Neonatology

authors： Petrakou E,Mouchtouri A,Levi E,Lipsou N,Xanthou M,Fotopoulos S

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Recently, sustained inflations (SI) during chest compression (CC) (CC+SI) have been suggested as an alternative to the current approach during neonatal resuscitation. No previous study compared CC+SI using CC rates of 90/min to the current 3:1 compression:ventilation ratio (C:V). OBJECTIVE:To determine whet...

journal_title：Neonatology

authors： Li ES,Görens I,Cheung PY,Lee TF,Lu M,O'Reilly M,Schmölzer GM

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:The clinical significance of early transient hypoglycemia (ETH), a frequent event in preterm newborns, is a highly controversial issue. In experimental models, hypoglycemia has been reported to cause oxidative stress. Among the reactive species, early generated peroxynitrite is responsible for protein nitrat...

journal_title：Neonatology

authors： Wayenberg JL,Cavedon C,Ghaddhab C,Lefèvre N,Bottari SP

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate whether a new MRI scoring system for preterm non-haemorrhagic white matter injury (WMI), derived from the analysis of the natural evolution of WMI throughout the neonatal period until term-equivalent age, can be used for outcome prediction. METHODS:Eighty-two infants <36...

journal_title：Neonatology

authors： Martinez-Biarge M,Groenendaal F,Kersbergen KJ,Benders MJNL,Foti F,van Haastert IC,Cowan FM,de Vries LS

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Meconium displaces surfactant from the alveolar surface and inhibits its function. The development of active synthetic surfactants is complicated, especially to synthesize the hydrophobic surfactant proteins SP-B and SP-C. A synthetic surfactant, CHF5633 containing SP-B and SP-C analogs, has been designed to...

journal_title：Neonatology

authors： Salvesen B,Curstedt T,Mollnes TE,Saugstad OD

更新日期：2014-01-01 00:00:00

abstract：:Volume resuscitation (VR) for the treatment of newborn shock is a rare but potentially lifesaving intervention. Conducting clinical studies to assess the effectiveness of VR in the delivery room during newborn stabilization is challenging. We review the available literature and current management guidelines to determi...

journal_title：Neonatology

authors： Finn D,Roehr CC,Ryan CA,Dempsey EM

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:With the increasing incidence of births of very preterm very-low-birth-weight infants, there is a demand for echocardiographic reference values of cardiac dimensions. OBJECTIVES:The aim of this study was to provide reference values of cardiac valve annulus diameters in a cohort of extremely preterm very-low...

journal_title：Neonatology

authors： van Ark AE,Molenschot MC,Wesseling MH,de Vries WB,Strengers JLM,Adams A,Breur JMPJ

更新日期：2018-01-01 00:00:00

abstract：AIM:Melatonin is a potent free radical scavenger and an indirect antioxidant. Knowledge about the behavior of melatonin secretion in the early neonatal period, which may relate to its properties at a vital stage during very high antioxidant demands, is limited. PATIENTS AND METHODS:We studied 35 newborns admitted to t...

journal_title：Neonatology

authors： Muñoz-Hoyos A,Bonillo-Perales A,Avila-Villegas R,González-Ripoll M,Uberos J,Florido-Navío J,Molina-Carballo A

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:Positive pressure ventilation (PPV) with T-Piece and self-inflating bag (SIB) during neonatal resuscitation after birth is associated with variability in ventilation. The use of a ventilator with respiratory function monitoring (RFM) for PPV, however, has not been evaluated. OBJECTIVE:To determine if vent...

journal_title：Neonatology

authors： Jain D,D'Ugard C,Aguilar A,Del Moral T,Bancalari E,Claure N

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:In high-risk newborns indirect hyperbilirubinemia can lead to acute bilirubin encephalopathy and kernicterus. Despite the current therapeutic modalities, preventing or reversing the neurotoxicity cannot be achieved in all infants. OBJECTIVE:To investigate the neuroprotective effects of hypothermia on biliru...

journal_title：Neonatology

authors： Kuter N,Aysit-Altuncu N,Ozturk G,Ozek E

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Around 10% of newborn infants require assistance during transition after birth. Heart rate (HR) is the most important clinical indicator to evaluate the clinical status of a newborn. AIM:Our study aimed to review all established and novel methods to detect HR in babies giving special consideration to non-in...

journal_title：Neonatology

authors： Anton O,Fernandez R,Rendon-Morales E,Aviles-Espinosa R,Jordan H,Rabe H

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Phenobarbitone (PB) is the first-line anti-convulsant for neonatal seizures. The use of peritoneal dialysis (PD) to enhance drug elimination in cases of neonatal PB overdose has not been reported. OBJECTIVE:To report a case of neonatal severe PB toxicity and review the elimination of PB by PD. METHODS:Asse...

journal_title：Neonatology

authors： Le Page AK,Stewart AE,Roehr CC,Johnstone LM,Graudins A

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Caffeine is a commonly used drug for apnea of prematurity. It may, however, also have a beneficial effect on bronchopulmonary dysplasia (BPD), which is the most common complication of extreme preterm birth. OBJECTIVES:To study the inflammatory, structural and functional effects of caffeine in an animal mode...

journal_title：Neonatology

authors： Nagatomo T,Jiménez J,Richter J,De Baere S,Vanoirbeek J,Naulaers G,Allegaert K,Croubels S,Deprest JA,Toelen J

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Cardiac troponin T (cTnT) has been proposed as specific biochemical marker for myocardial infarction in adults. Cardiac function in neonates could be influenced by the severity of respiratory distress and its ventilatory management. OBJECTIVES:To establish a normal range of cTnT in healthy neonates, compare...

journal_title：Neonatology

authors： Awada H,Al-Tannir M,Ziade MF,Alameh J,El Rajab M

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVES:Non-invasive cardiac output monitoring is a potentially useful clinical tool in the neonatal setting. Our aim was to evaluate a new method of non-invasive continuous cardiac output (CO) measurement (NICOM™) based on the principle of bioreactance in neonates. METHODS:In this prospective observational study, ...

journal_title：Neonatology

authors： Weisz DE,Jain A,McNamara PJ,EL-Khuffash A

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Inhaled glucocorticoids may increase the risk of pneumonia in adults. Thus, respiratory infections may be a potential explanation for the non-significantly increased mortality seen in the glucocorticoid group in the largest randomized trial on inhaled glucocorticoids for preventing bronchopulmonary dysplasia...

journal_title：Neonatology

authors： Koch A,Kreutzer K,von Oldershausen G,Poets CF,Bassler D,NEuroSIS Trial Group.

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:Oral propranolol has improved the treatment of infantile hemangiomas, and a pediatric oral solution of propranolol has recently been licensed in the USA and Europe. In very preterm infants, infantile hemangiomas are associated with the occurrence of retinopathy of prematurity (ROP), and both diseases share...

journal_title：Neonatology

authors： Bührer C,Bassler D

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Corticosteroids have been used widely after birth in preterm infants with respiratory failure; hydrocortisone may be preferable to other corticosteroids for this purpose. OBJECTIVES:To determine if postnatal hydrocortisone is useful to prevent or treat bronchopulmonary dysplasia (BPD) in preterm infants. M...

journal_title：Neonatology

authors： Doyle LW,Ehrenkranz RA,Halliday HL

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Hypoxic-ischaemic encephalopathy is a major cause of neurologic impairment and mortality in neonates. Early knowledge of brain injury is important to guide therapeutic decisions and reliably inform the parents. Increased secretoneurin levels have been detected in adult patients suffering from brain injury an...

journal_title：Neonatology

authors： Wechselberger K,Schmid A,Posod A,Höck M,Neubauer V,Fischer-Colbrie R,Kiechl-Kohlendorfer U,Griesmaier E

更新日期：2016-01-01 00:00:00

abstract：:The aim of this article is to educate neonatal caregivers about metagenomics. This scientific field uses novel and ever changing molecular methods to identify how infants become colonized with microbes after birth. Publications using metagenomics appear infrequently in the neonatal literature because clinicians are un...

journal_title：Neonatology

authors： Sherman MP,Minnerly J,Curtiss W,Rangwala S,Kelley ST

更新日期：2014-01-01 00:00:00