当前位置： SCI文献检索 > Neonatology期刊下所有文献 > Accuracy of Brain Natriuretic Peptide for Diagnosing Pulmonary Hypertension in Severe Bronchopulmonary Dysplasia.

Accuracy of Brain Natriuretic Peptide for Diagnosing Pulmonary Hypertension in Severe Bronchopulmonary Dysplasia.

Abstract：

BACKGROUND:Premature infants with severe bronchopulmonary dysplasia (sBPD) are at risk of pulmonary hypertension (PH). Serum brain natriuretic peptide (BNP) is used to predict disease severity in adult PH. Its diagnostic utility in sBPD-associated PH is unknown. OBJECTIVE:The aim of this paper was to determine the accuracy of BNP, against echocardiogram (echo), to diagnose PH in infants born <32 weeks' gestation with sBPD. METHODS:We conducted a retrospective cohort study of all infants with sBPD with an echo and BNP within a 24-h period, at ≥36 weeks postmenstrual age. PH was defined as: right ventricular pressure >½ systemic blood pressure estimated from tricuspid regurgitant jet or patent ductus arteriosus (PDA) velocity, bidirectional or right-to left-PDA, and/or flat/bowing ventricular septum at end-systole. Receiver-operating characteristic (ROC) curves were constructed to test the diagnostic accuracy of BNP. RESULTS:Of 128 infants, 68 (53%) had echo evidence of PH. BNP was higher among the infants with PH (median [interquartile range]: 127 pg/mL [39-290] vs. 35 [20-76], p < 0.001). The area under the ROC curve for diagnosing PH using BNP was 0.74 (95% CI 0.66-0.83). At an optimal cutpoint of 130 pg/mL, BNP correctly classified the presence or absence of PH in 70% of the infants (specificity: 92, sensitivity: 50%). CONCLUSIONS:BNP, relative to concurrent echo, demonstrated moderate accuracy for diagnosing PH in this cohort of preterm infants with sBPD. BNP may help rule in PH in this population but has low utility to rule out the disease.

journal_name

Neonatology

journal_title

Neonatology

authors

Avitabile CM,Ansems S,Wang Y,Fraga MV,Kirpalani HM,Zhang H,Mercer-Rosa L,Jensen EA

doi

10.1159/000499082

subject

Has Abstract

pub_date

2019-01-01 00:00:00

pages

147-153

issue

2

eissn

1661-7800

issn

1661-7819

pii

000499082

journal_volume

116

pub_type

杂志文章

相关文献

Neonatology文献大全
  • Diagnosis of gastro-oesophageal reflux in preterm infants: sonography vs. pH-monitoring.

    abstract：OBJECTIVES:To compare the ultrasound examination with pH-metry in order to evaluate the diagnostic accuracy of sonography for diagnosis of gastro-oesophageal reflux (GOR) in preterm infants. METHODS:A prospective study was conducted on 31 premature infants <34 weeks with clinically diagnosed GOR. First, they underwent...

    journal_title：Neonatology

    pub_type： 临床试验,杂志文章

    doi：10.1159/000097447

    authors： Pezzati M,Filippi L,Psaraki M,Rossi S,Dani C,Tronchin M,Rubaltelli FF

    更新日期：2007-01-01 00:00:00

  • Insulin-like growth factor-1 and anti-vascular endothelial growth factor in retinopathy of prematurity: has the time come?

    abstract：:Treatment of retinopathy of prematurity (ROP) is currently evolving. Novel therapeutic options are emerging that have the potential to complement existing therapies and improve treatment outcomes. However, any new therapeutic option must be thoroughly evaluated before existing (and successful) treatment paradigms can ...

    journal_title：Neonatology

    pub_type： 杂志文章,评审

    doi：10.1159/000365132

    authors： Stahl A,Hellstrom A,Smith LE

    更新日期：2014-01-01 00:00:00

  • Non-invasive cardiac output monitoring in neonates using bioreactance: a comparison with echocardiography.

    abstract：OBJECTIVES:Non-invasive cardiac output monitoring is a potentially useful clinical tool in the neonatal setting. Our aim was to evaluate a new method of non-invasive continuous cardiac output (CO) measurement (NICOM™) based on the principle of bioreactance in neonates. METHODS:In this prospective observational study, ...

    journal_title：Neonatology

    pub_type： 杂志文章

    doi：10.1159/000337295

    authors： Weisz DE,Jain A,McNamara PJ,EL-Khuffash A

    更新日期：2012-01-01 00:00:00

  • Respiratory function and near infrared spectroscopy recording during cardiopulmonary resuscitation in an extremely preterm newborn.

    abstract：:We describe a case highlighting several controversial and important topics regarding neonatal cardiopulmonary resuscitation (CPR). Current neonatal guidelines recommend a 3:1 compression:ventilation ratio; however, the most effective ratio of delivering chest compressions (CC) remains controversial. We report a case o...

    journal_title：Neonatology

    pub_type： 杂志文章

    doi：10.1159/000357609

    authors： Li ES,Cheung PY,Pichler G,Aziz K,Schmölzer GM

    更新日期：2014-01-01 00:00:00

  • Clinical Outcome for Congenital Diaphragmatic Hernia at the Age of 1 Year in the Era of Fetal Intervention.

    abstract：BACKGROUND:Congenital diaphragmatic hernia (CDH) is an abnormal development of the diaphragm leading to high neonatal mortality and morbidity. Beyond the neonatal period, prospective data on overall long-term outcome in CDH survivors is scarce. In particular, for those treated with fetoscopic endoluminal tracheal occlu...

    journal_title：Neonatology

    pub_type： 杂志文章

    doi：10.1159/000479145

    authors： Van Ginderdeuren E,Allegaert K,Decaluwe H,Deprest J,Debeer A,Proesmans M

    更新日期：2017-01-01 00:00:00

  • Cardiac Valve Annulus Diameters in Extremely Preterm Infants: A Cross-Sectional Echocardiographic Study.

    abstract：BACKGROUND:With the increasing incidence of births of very preterm very-low-birth-weight infants, there is a demand for echocardiographic reference values of cardiac dimensions. OBJECTIVES:The aim of this study was to provide reference values of cardiac valve annulus diameters in a cohort of extremely preterm very-low...

    journal_title：Neonatology

    pub_type： 杂志文章

    doi：10.1159/000488387

    authors： van Ark AE,Molenschot MC,Wesseling MH,de Vries WB,Strengers JLM,Adams A,Breur JMPJ

    更新日期：2018-01-01 00:00:00

  • Identifying Risk Factors Shared by Bronchopulmonary Dysplasia, Severe Retinopathy, and Cystic Periventricular Leukomalacia in Very Preterm Infants for Targeted Intervention.

    abstract：BACKGROUND:Bronchopulmonary dysplasia (BPD), severe retinopathy of prematurity (sROP), and cystic periventricular leukomalacia (cPVL) are 3 major morbidities with long-term neurodevelopmental impairments in preterm infants. OBJECTIVE:To investigate the strength of associations and identify key risk factors shared by B...

    journal_title：Neonatology

    pub_type： 杂志文章,多中心研究

    doi：10.1159/000487505

    authors： Wang LW,Lin YC,Wang ST,Huang CC,on behalf of the Taiwan Premature Infant Developmental Collaborative Study Group.

    更新日期：2018-01-01 00:00:00

  • Increased Carbon Monoxide Washout Rates in Newborn Infants.

    abstract：BACKGROUND:Endogenous carbon monoxide (CO) production is primarily due to heme degradation, which also results in the equimolar production of bilirubin. Thus, estimates of total body CO production can serve as indices of total body bilirubin formation. The elimination rate of CO from a person's body (CO washout rate) a...

    journal_title：Neonatology

    pub_type： 杂志文章

    doi：10.1159/000503635

    authors： Stevenson DK,Wong RJ,Ostrander CR,Maric I,Vreman HJ,Cohen RS

    更新日期：2020-01-01 00:00:00

  • Activation of the mitogen-activated protein kinases and Akt in response to pulmonary artery banding in the fetal sheep heart is developmentally regulated.

    abstract：BACKGROUND:The postnatal heart responds to biomechanical stress with hypertrophy. The fetal heart may also undergo hyperplasia, but the percentage of mitotically active cardiomyocytes decreases throughout gestation. The signaling pathways controlling growth and proliferation in the fetal heart are poorly understood. O...

    journal_title：Neonatology

    pub_type： 杂志文章

    doi：10.1159/000107729

    authors： Olson AK,Protheroe KN,Scholz TD,Segar JL

    更新日期：2008-01-01 00:00:00

  • Inhaled Glucocorticoids and Pneumonia in Preterm Infants: Post Hoc Results from the NEuroSIS Trial.

    abstract：BACKGROUND:Inhaled glucocorticoids may increase the risk of pneumonia in adults. Thus, respiratory infections may be a potential explanation for the non-significantly increased mortality seen in the glucocorticoid group in the largest randomized trial on inhaled glucocorticoids for preventing bronchopulmonary dysplasia...

    journal_title：Neonatology

    pub_type： 杂志文章,随机对照试验

    doi：10.1159/000468507

    authors： Koch A,Kreutzer K,von Oldershausen G,Poets CF,Bassler D,NEuroSIS Trial Group.

    更新日期：2017-01-01 00:00:00

  • Surfactant and noninvasive ventilation.

    abstract：:There is mounting evidence that early continuous positive airway pressure (CPAP) from birth is feasible and safe even in very preterm infants. However, many infants will develop respiratory distress syndrome (RDS) and require surfactant treatment. Combining a noninvasive ventilation approach with a strategy for surfac...

    journal_title：Neonatology

    pub_type： 杂志文章,评审

    doi：10.1159/000381122

    authors： Blennow M,Bohlin K

    更新日期：2015-01-01 00:00:00

  • Randomized crossover comparison of proportional assist ventilation and patient-triggered ventilation in extremely low birth weight infants with evolving chronic lung disease.

    abstract：BACKGROUND:Refinement of ventilatory techniques remains a challenge given the persistence of chronic lung disease of preterm infants. METHODS:To test the hypothesis that proportional assist ventilation (PAV) will allow to lower the ventilator pressure at equivalent fractions of inspiratory oxygen (FiO(2)) and arterial...

    journal_title：Neonatology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1159/000098376

    authors： Schulze A,Rieger-Fackeldey E,Gerhardt T,Claure N,Everett R,Bancalari E

    更新日期：2007-01-01 00:00:00

  • Adrenal function in preterm infants undergoing patent ductus arteriosus ligation.

    abstract：BACKGROUND:Targeted milrinone treatment for low left ventricular output (LVO) reduces the incidence of acute cardiorespiratory instability following ligation of patent ductus arteriosus (PDA) in preterm infants. Despite this, some infants continue to experience postoperative deterioration. Adrenal insufficiency related...

    journal_title：Neonatology

    pub_type： 杂志文章

    doi：10.1159/000350017

    authors： EL-Khuffash A,McNamara PJ,Lapointe A,Jain A

    更新日期：2013-01-01 00:00:00

  • Early transient hypoglycemia is associated with increased albumin nitration in the preterm infant.

    abstract：BACKGROUND:The clinical significance of early transient hypoglycemia (ETH), a frequent event in preterm newborns, is a highly controversial issue. In experimental models, hypoglycemia has been reported to cause oxidative stress. Among the reactive species, early generated peroxynitrite is responsible for protein nitrat...

    journal_title：Neonatology

    pub_type： 杂志文章

    doi：10.1159/000326936

    authors： Wayenberg JL,Cavedon C,Ghaddhab C,Lefèvre N,Bottari SP

    更新日期：2011-01-01 00:00:00

  • Chest Compressions during Sustained Inflations Improve Recovery When Compared to a 3:1 Compression:Ventilation Ratio during Cardiopulmonary Resuscitation in a Neonatal Porcine Model of Asphyxia.

    abstract：BACKGROUND:Recently, sustained inflations (SI) during chest compression (CC) (CC+SI) have been suggested as an alternative to the current approach during neonatal resuscitation. No previous study compared CC+SI using CC rates of 90/min to the current 3:1 compression:ventilation ratio (C:V). OBJECTIVE:To determine whet...

    journal_title：Neonatology

    pub_type： 杂志文章

    doi：10.1159/000477998

    authors： Li ES,Görens I,Cheung PY,Lee TF,Lu M,O'Reilly M,Schmölzer GM

    更新日期：2017-01-01 00:00:00

  • Time is brain: starting therapeutic hypothermia within three hours after birth improves motor outcome in asphyxiated newborns.

    abstract：OBJECTIVE:Therapeutic hypothermia (HT) is the standard treatment for newborns after perinatal asphyxia. Preclinical studies report that HT is more effective when started early. METHODS:Eighty cooled newborns were analyzed and grouped according to when cooling was started after birth: early (≤180 min) or late (>181 min...

    journal_title：Neonatology

    pub_type： 杂志文章

    doi：10.1159/000353948

    authors： Thoresen M,Tooley J,Liu X,Jary S,Fleming P,Luyt K,Jain A,Cairns P,Harding D,Sabir H

    更新日期：2013-01-01 00:00:00

  • Diagnostic value of an interleukin-6 bedside test in term and preterm neonates at the time of clinical suspicion of early- and late-onset bacterial infection.

    abstract：BACKGROUND:For quick detection or exclusion of neonatal early-onset bacterial infection (EOBI) or late-onset bacterial infection (LOBI), interleukin (IL)-6 is used. Its clinical use is sometimes limited due to prolonged recall times. Therefore, an IL-6 bedside test was established. OBJECTIVE:To compare the diagnostic ...

    journal_title：Neonatology

    pub_type： 杂志文章

    doi：10.1159/000336632

    authors： Batfalsky A,Lohr A,Heussen N,Neunhoeffer F,Orlikowsky TW

    更新日期：2012-01-01 00:00:00

  • History of the ductus arteriosus: 1. Anatomy and spontaneous closure.

    abstract：:Ductus arteriosus and foramen ovale were described by Galen without understanding their functions. His beliefs in soul localization and spiritization within the left ventricle established religious pneumatology which became a theological need in the Middle Ages. Pulmonary transit was recognized by Servetus and Colombo...

    journal_title：Neonatology

    pub_type： 历史文章,杂志文章

    doi：10.1159/000308367

    authors： Obladen M

    更新日期：2011-01-01 00:00:00

  • Impact of Xenon on CLIC4 and Bcl-2 Expression in Lipopolysaccharide and Hypoxia-Ischemia-Induced Periventricular White Matter Damage.

    abstract：BACKGROUND:Premature birth is a significant health care burden. Xenon (Xe) is a general anesthetic with neuroprotective effects. OBJECTIVES:Here, we investigate the neuroprotective role of Xe in a lipopolysaccharide (LPS)- and hypoxia-ischemia (HI)-induced white matter damage (WMD) model. METHODS:Three-day-old Spragu...

    journal_title：Neonatology

    pub_type： 杂志文章

    doi：10.1159/000487220

    authors： Yin X,Zhao J,Jiang H,Li L,Jiang J,Xi H,Peng X,Yin X,Shi X,Zhang L

    更新日期：2018-01-01 00:00:00

  • Lack of Evidence for Time or Dose Relationship between Antenatal Magnesium Sulfate and Intestinal Injury in Extremely Preterm Neonates.

    abstract：BACKGROUND:Recent studies reported conflicting results on the relationship between antenatal magnesium sulfate (MgSO4) exposure and neonatal intestinal injury. Most studies have not assessed MgSO4 exposure quantitatively and none reported the exposure timing. OBJECTIVES:The aim of this work was to assess whether there...

    journal_title：Neonatology

    pub_type： 杂志文章

    doi：10.1159/000497412

    authors： Mikhael M,Bronson C,Zhang L,Curran M,Rodriguez H,Bhakta KY

    更新日期：2019-01-01 00:00:00

  • Cardiac troponin T: a useful early marker for cardiac and respiratory dysfunction in neonates.

    abstract：BACKGROUND:Cardiac troponin T (cTnT) has been proposed as specific biochemical marker for myocardial infarction in adults. Cardiac function in neonates could be influenced by the severity of respiratory distress and its ventilatory management. OBJECTIVES:To establish a normal range of cTnT in healthy neonates, compare...

    journal_title：Neonatology

    pub_type： 临床试验,杂志文章

    doi：10.1159/000100964

    authors： Awada H,Al-Tannir M,Ziade MF,Alameh J,El Rajab M

    更新日期：2007-01-01 00:00:00

  • Caffeine Prevents Hyperoxia-Induced Functional and Structural Lung Damage in Preterm Rabbits.

    abstract：BACKGROUND:Caffeine is a commonly used drug for apnea of prematurity. It may, however, also have a beneficial effect on bronchopulmonary dysplasia (BPD), which is the most common complication of extreme preterm birth. OBJECTIVES:To study the inflammatory, structural and functional effects of caffeine in an animal mode...

    journal_title：Neonatology

    pub_type： 杂志文章

    doi：10.1159/000442937

    authors： Nagatomo T,Jiménez J,Richter J,De Baere S,Vanoirbeek J,Naulaers G,Allegaert K,Croubels S,Deprest JA,Toelen J

    更新日期：2016-01-01 00:00:00

  • End-of-Life Care and Survival without Major Brain Damage in Newborns at the Limit of Viability.

    abstract：BACKGROUND:The probabilities of survival and survival without major brain damage (MBD) are low in newborns at the limit of viability. Survival without MBD constitutes a major concern for parents and professionals. OBJECTIVES:To know the probabilities of survival without MBD in newborns ≤26 weeks' gestational age (GA) ...

    journal_title：Neonatology

    pub_type： 杂志文章

    doi：10.1159/000452195

    authors： García-Muñoz Rodrigo F,Urquía Martí L,García Hernández JÁ,Figueras Aloy J,García-Alix Pérez A,SEN1500 Network of the Spanish Neonatal Society.

    更新日期：2017-01-01 00:00:00

  • High faecal calprotectin levels in healthy, exclusively breast-fed infants.

    abstract：BACKGROUND:Faecal calprotectin has been proposed as a sensitive marker for gastrointestinal inflammation in children and adults. High levels have been reported in healthy newborns and during the first months of life; the effect of the kind of feeding on the calprotectin concentration in stools is controversial. OBJECT...

    journal_title：Neonatology

    pub_type： 杂志文章

    doi：10.1159/000255161

    authors： Savino F,Castagno E,Calabrese R,Viola S,Oggero R,Miniero R

    更新日期：2010-06-01 00:00:00

  • Hyperglycaemic Preterm Babies Have Sex Differences in Insulin Secretion.

    abstract：BACKGROUND:Hyperglycaemia is a common complication of prematurity and is associated with neonatal mortality and morbidity, yet the aetiology is incompletely understood. C-peptide has been used in adults to estimate endogenous insulin secretion due to its simple clearance kinetics. OBJECTIVE:To determine insulin secret...

    journal_title：Neonatology

    pub_type： 杂志文章,随机对照试验

    doi：10.1159/000381206

    authors： Dickson JL,Chase JG,Pretty CG,Gunn CA,Alsweiler JM

    更新日期：2015-01-01 00:00:00

  • Diagnosis of Hemidiaphragmatic Paresis in a Preterm Infant with Transcutaneous Electromyography: A Case Report.

    abstract：:Transcutaneous electromyography of the diaphragm (dEMG) is a noninvasive and easy applicable tool to measure the electrical activity of the diaphragm. dEMG monitoring has recently been introduced in the neonatal intensive care unit as a novel cardiorespiratory monitor providing direct information on diaphragmatic brea...

    journal_title：Neonatology

    pub_type： 杂志文章

    doi：10.1159/000381207

    authors： Kraaijenga JV,Hutten GJ,de Jongh FH,van Kaam AH

    更新日期：2015-01-01 00:00:00

  • Randomised Controlled Trials for Informing Perinatal Care.

    abstract：BACKGROUND:Randomised controlled trials provide the best evidence for the effects of interventions and are a key tool in the effort to improve the care and outcomes for newborn infants. METHODS:We discuss the role of randomisation for minimising selection bias in clinical trials and describe examples of seminal trials...

    journal_title：Neonatology

    pub_type： 杂志文章,评审

    doi：10.1159/000499881

    authors： Gale C,McGuire W,Juszczak E

    更新日期：2020-01-01 00:00:00

  • Persistent periventricular echogenicities in preterms are not related to smaller brains at term-equivalent age.

    abstract：BACKGROUND:Periventricular white matter (PWM) is particularly vulnerable in very preterm infants. Non-cystic white matter injury, known as non-cystic periventricular leukomalacia (ncPVL), is the commonest 'lesion' affecting the preterm brain. There is no consensus about whether ncPVL can be reliably identified from cer...

    journal_title：Neonatology

    pub_type： 杂志文章

    doi：10.1159/000357937

    authors： Graça AM,Cardoso K,Costa J,Cowan F

    更新日期：2014-01-01 00:00:00

  • A randomised crossover trial of clinical algorithm for oxygen saturation targeting in preterm infants with frequent desaturation episodes.

    abstract：OBJECTIVES:Strategies for oxygen therapy for preterm infants, such as the Vermont-Oxford's 'Breathsavers' guidelines, seek to strike a balance between the potential risks of the extremes of hyperoxia and hypoxia in preterm infants. Using an algorithm based on those guidelines, we aimed to compare the proportion of time...

    journal_title：Neonatology

    pub_type： 杂志文章,随机对照试验

    doi：10.1159/000368295

    authors： Clarke A,Yeomans E,Elsayed K,Medhurst A,Berger P,Skuza E,Tan K

    更新日期：2015-01-01 00:00:00

  • Research on neonatal microbiomes: what neonatologists need to know.

    abstract：:The aim of this article is to educate neonatal caregivers about metagenomics. This scientific field uses novel and ever changing molecular methods to identify how infants become colonized with microbes after birth. Publications using metagenomics appear infrequently in the neonatal literature because clinicians are un...

    journal_title：Neonatology

    pub_type： 杂志文章,评审

    doi：10.1159/000354944

    authors： Sherman MP,Minnerly J,Curtiss W,Rangwala S,Kelley ST

    更新日期：2014-01-01 00:00:00