Abstract:
:Readily available vanadyl acetylacetonate was found to oxidize the allylic sites of Δ(5) steroidal alcohols without protection of hydroxyl groups. Cholesterol, dehydroepiandrosterone, cholesterol benzoate, cholesterol acetate, pregnenolone, and 5-pregnen-3,20-diene were oxidized to 7-keto products using vanadyl acetylacetonate in one pot reactions at room temperature in the presence of oxygen and water.
journal_name
Steroidsjournal_title
Steroidsauthors
Grainger WS,Parish EJdoi
10.1016/j.steroids.2015.06.005subject
Has Abstractpub_date
2015-09-01 00:00:00pages
103-9eissn
0039-128Xissn
1878-5867pii
S0039-128X(15)00182-8journal_volume
101pub_type
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