A comparison of the antinociceptive and behavioral effects of intrathecally administered opiates, alpha-2-adrenergic agonists, and local anesthetics in mice and rats.

abstract：IMPLICATIONS:Tizanidine was given systemically to rats with experimental postoperative pain. Partial pain relief was obtained, but the effect was not clinically significant. Although systemic tizanidine is effective in relieving experimental neuropathic pain, it is not as effective for postoperative pain. ...

journal_title：Anesthesia and analgesia

authors： Hord AH,Denson DD,Azevedo MI

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Perioperative respiratory adverse events (PRAEs) account for the major cause of morbidity and mortality in children undergoing general anesthesia. In our institutional clinical practice, we suspected that African American children experienced untoward respiratory events more frequently than other racial grou...

journal_title：Anesthesia and analgesia

authors： Tariq S,Syed M,Martin T,Zhang X,Schmitz M

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Given the controversy regarding the use of droperidol and the high cost of the 5-HT3 antagonists, a cost-effective alternative for routine use as a prophylactic antiemetic would be desirable. We designed two parallel, randomized, double-blind sham and placebo-controlled studies to compare the early and late ...

journal_title：Anesthesia and analgesia

authors： White PF,Tang J,Song D,Coleman JE,Wender RH,Ogunnaike B,Sloninsky A,Kapu R,Shah M,Webb T

更新日期：2007-01-01 00:00:00

abstract：UNLABELLED:A new infraclavicular brachial plexus block method has the patient supine with an adducted arm. The target is any of the three cords behind the pectoralis minor muscle. The point of needle insertion is the intersection between the clavicle and the coracoid process. The needle is advanced 0 degrees -30 degree...

journal_title：Anesthesia and analgesia

authors： Klaastad Ø,Smith HJ,Smedby O,Winther-Larssen EH,Brodal P,Breivik H,Fosse ET

更新日期：2004-01-01 00:00:00

abstract：UNLABELLED:Evidence suggests that early postischemic hyperemia is mediated by both neurological and vascular mechanisms. We hypothesized that if neuronal activity were primarily responsible for reperfusion hyperemia, then electrocerebral silence induced by intracarotid anesthetics (propofol and pentothal) would attenua...

journal_title：Anesthesia and analgesia

authors： Joshi S,Wang M,Nishanian EV,Emerson RG

更新日期：2004-05-01 00:00:00

abstract：:The development of a technique for studying spinal dorsal horn electrophysiology in intact, awake, drug-free cats enables the study of spinal sites and mechanisms of action of anesthetic and analgesic agents in a system that more closely reflects normal physiology. Using this technique, we reevaluated the effect of ke...

journal_title：Anesthesia and analgesia

authors： Collins JG

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Adverse effects of hydroxyethyl starches (HESs) have been verified in patients suffering from sepsis or kidney disease, but not in surgical patients at large. The investigation aimed to determine whether the use of HES 130/0.4 was associated with the incidence of acute postinterventional adverse events compa...

journal_title：Anesthesia and analgesia

authors： Pagel JI,Rehm M,Kammerer T,Hulde N,Speck E,Briegel J,Reinholz F,Crispin A,Hofmann-Kiefer KF

更新日期：2018-06-01 00:00:00

abstract：:Clonidine decreases central sympathetic activity and anesthetic requirement. We tested whether clonidine improves outcome from incomplete ischemia of the brain in rats. Control rats were anesthetized with 25 micrograms.kg-1.h-1 of intravenous fentanyl and inhalation of 70% nitrous oxide (N2O). Clonidine-treated rats r...

journal_title：Anesthesia and analgesia

authors： Hoffman WE,Cheng MA,Thomas C,Baughman VL,Albrecht RF

更新日期：1991-10-01 00:00:00

abstract：UNLABELLED:Although isoflurane can reduce ischemic neuronal injury after short postischemic recovery intervals, this neuroprotective efficacy is not sustained. Neuronal apoptosis can contribute to the gradual increase in infarct size after ischemia. This suggests that isoflurane, although capable of reducing early neur...

journal_title：Anesthesia and analgesia

authors： Kawaguchi M,Drummond JC,Cole DJ,Kelly PJ,Spurlock MP,Patel PM

更新日期：2004-03-01 00:00:00

abstract：:External cephalic version is a technique that decreases the need for cesarean delivery in patients with breech presentation. Several techniques exist to increase the success of external cephalic version; however, there are no studies comparing different tocolytics in patients who also received neuraxial anesthesia. We...

journal_title：Anesthesia and analgesia

authors： Katz D,Riley K,Kim E,Beilin Y

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Variations in the butyrylcholinesterase (BCHE) gene can prolong neuromuscular block after the administration of the neuromuscular blocking drugs succinylcholine and mivacurium. The most frequent variations in the BCHE gene are the atypical (A) and Kalow (K) variants. We, therefore, developed a detection appr...

journal_title：Anesthesia and analgesia

authors： Levano S,Keller D,Schobinger E,Urwyler A,Girard T

更新日期：2008-01-01 00:00:00

abstract：:Ondansetron and droperidol are both effective prophylactic antiemetics for gynecologic outpatient procedures. However, increased drowsiness, delayed discharge, and postdischarge restlessness may occur with droperidol, and ondansetron is costly. In this prospective, randomized, double-blind, placebo-controlled study in...

journal_title：Anesthesia and analgesia

authors： Tang J,Watcha MF,White PF

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:Central poststroke pain (CPSP) is a disabling morbidity occurring in 8%-14% of patients with stroke. It is infrequently recognized and difficult to manage. OBJECTIVE:We systematically reviewed the pathophysiology and treatment of CPSP. METHODS:We conducted a Medline search using the key words "central post...

journal_title：Anesthesia and analgesia

authors： Kumar B,Kalita J,Kumar G,Misra UK

更新日期：2009-05-01 00:00:00

abstract：UNLABELLED:Proinflammatory cytokines have been implicated in mediating myocardial dysfunction associated with major surgery. We investigated the profile of proinflammatory cytokines and the association of cytokine levels with myocardial function after esophagectomy. We studied 12 patients who underwent subtotal esophag...

journal_title：Anesthesia and analgesia

authors： Nakanishi K,Takeda S,Terajima K,Takano T,Ogawa R

更新日期：2000-08-01 00:00:00

abstract：:We determined the cardiovascular effects of 0.91, 1.34, and 1.74 MAC of desflurane/nitrous oxide anesthesia (60% inspired nitrous oxide contributed 0.5 MAC at each level) in 12 healthy, normocapnic male volunteers. Desflurane/nitrous oxide anesthesia decreased systemic blood pressures, cardiac index, stroke volume ind...

journal_title：Anesthesia and analgesia

authors： Cahalan MK,Weiskopf RB,Eger EI 2nd,Yasuda N,Ionescu P,Rampil IJ,Lockhart SH,Freire B,Peterson NA

更新日期：1991-08-01 00:00:00

abstract：UNLABELLED:Because inhibition of voltage-dependent Ca(2+) channels can be a mechanism underlying general anesthesia, we examined sensitivities to propofol and halothane in mice lacking the R-type (Ca(v)2.3) channel widely expressed in neurons. Sleep time after propofol injection (26 mg/kg IV) and halothane MAC(RR) and ...

journal_title：Anesthesia and analgesia

authors： Takei T,Saegusa H,Zong S,Murakoshi T,Makita K,Tanabe T

更新日期：2003-07-01 00:00:00

abstract：:The purpose of these experiments was to analyze the cerebrovascular and cerebral metabolic effects of midazolam, a short-acting water-soluble benzodiazepine, and to investigate its interaction with alcohol in rats. A benzodiazepine antagonist, 3-carbo-t-butoxy-beta-carboline (beta-CCT), was used to test the role of th...

journal_title：Anesthesia and analgesia

authors： Van Gorder PN,Hoffman WE,Baughman V,Albrecht RF,Miletich DJ,Guzman F,Cook JM

更新日期：1985-02-01 00:00:00

abstract：:We investigated the effects of halothane on changes in cardiac function during hypoperfusion and recovery of function after reperfusion in the isolated perfused guinea pig heart. Heart rate, atrioventricular (AV) conduction time, the incidence and severity of dysrhythmias, and isovolumetric left ventricular systolic p...

journal_title：Anesthesia and analgesia

authors： Buljubasic N,Marijic J,Stowe DF,Kampine JP,Bosnjak ZJ

更新日期：1992-03-01 00:00:00

abstract：:Cytokine release during surgery can produce a long-lasting hyperalgesia. Thus, preoperatively-administered cytokine inhibitors might reduce the production of cytokines, decreasing central nervous system sensitization and improving the quality of postoperative pain relief. We investigated the hypothesis that preincisio...

journal_title：Anesthesia and analgesia

authors： Lu CH,Chao PC,Borel CO,Yang CP,Yeh CC,Wong CS,Wu CT

更新日期：2004-11-01 00:00:00

abstract：:To improve operating room workflow, an internal transfer pricing system (ITPS) for anesthesia services was introduced in our hospital in 2001. The basic principle of the ITPS is that the department of anesthesia receives reimbursement only for the surgically controlled time, not for anesthesia-controlled time (ACT). A...

journal_title：Anesthesia and analgesia

authors： Schuster M,Standl T,Reissmann H,Kuntz L,Am Esch JS

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Severe exacerbation of chronic neuropathic pain often requires morphine in patients already treated with drugs such as tricyclic antidepressants, carbamazepine and gabapentin. However, it is unclear if a combination of these drugs intensifies the effects of morphine on the respiratory system and, if so, whet...

journal_title：Anesthesia and analgesia

authors： Kozer E,Levichek Z,Hoshino N,Kapur B,Leombruno J,Taguchi N,Garcia-Bournissen F,Koren G,Ito S

更新日期：2008-10-01 00:00:00

abstract：:Morphine plasma concentrations were determined in six patients receiving kidney transplants from living-related donors, and nine patients receiving kidney transplants from cadavers. The total cold ischemic time was about 2 hr for kidneys from living-related donors and 14 hr for those from cadavers. After an intravenou...

journal_title：Anesthesia and analgesia

authors： Sear J,Moore A,Hunniset A,Baldwin D,Allen M,Hand C,McQuay H,Morris P

更新日期：1985-11-01 00:00:00

abstract：:The effect of intravenous (IV) nitroglycerin (NTG) on perioperative myocardial ischemia as detected by single pass radionuclide angiocardiography was studied in 20 patients scheduled for elective coronary artery bypass grafting (CABG). Ten patients, selected at random, received IV NTG 1 microgram.kg-1.min-1 (NTG group...

journal_title：Anesthesia and analgesia

authors： Hart AP,Camporesi EM,Sell TL,Croughwell N,Silva R,Jones RH,McIntyre RW,Stanley TE,Reves JG

更新日期：1989-06-01 00:00:00

abstract：:Hemispheric synchronization is currently promoted as a treatment for preoperative anxiety and for reduction of intraoperative anesthetic and analgesic consumption. We designed this study to examine the effect of Hemisync sounds on anesthetic hypnotic depth. After obtaining informed consent, we randomized subjects unde...

journal_title：Anesthesia and analgesia

authors： Dabu-Bondoc S,Drummond-Lewis J,Gaal D,McGinn M,Caldwell-Andrews AA,Kain ZN

更新日期：2003-09-01 00:00:00

abstract：UNLABELLED:Suppression of nitric oxide (NO) production alters the toxicity of cocaine and bupivacaine. We undertook this study to determine whether the systemic toxicity of two other local anesthetics that differ in antiarrhythmic activity, plasma clearance, and biotransformation are similarly affected by nitric oxide ...

journal_title：Anesthesia and analgesia

authors： Heavner JE,Shi B,Pitkänen M

更新日期：1999-04-01 00:00:00

abstract：:Large doses of morphine sulfate have been reported to cause myocardial lactate production and reduction in coronary blood flow in animals. Similar effects with clinical doses in man would significantly alter the management of cardiac patients. Eleven adult patients with significant coronary arterial disease and normal...

journal_title：Anesthesia and analgesia

authors： Sethna DH,Moffitt EA,Gray RJ,Bussell J,Raymond M,Conklin C,Shell WE,Matloff JM

更新日期：1982-02-01 00:00:00

abstract：:In the past, it was common practice to use a high tidal volume (VT) during intraoperative ventilation, because this reduced the need for high oxygen fractions to compensate for the ventilation-perfusion mismatches due to atelectasis in a time when it was uncommon to use positive end-expiratory pressure (PEEP) in the o...

journal_title：Anesthesia and analgesia

authors： Hol L,Nijbroek SGLH,Schultz MJ

更新日期：2020-12-01 00:00:00

abstract：:The nucleus raphe magnus (NRM) is an important descending pain inhibitory system. We postulated that the analgesic action of supraspinally administered opiates results from increased descending inhibitory control of the NRM. We tested whether fentanyl activates NRM neurons in the rat slice preparation using extra-cell...

journal_title：Anesthesia and analgesia

authors： Ohta Y,Alojado ME,Kemmotsu O

更新日期：1995-05-01 00:00:00

abstract：UNLABELLED:With pressure support ventilation (PSV), each PSV breath is flow-cycled, and the breath termination criterion (TC) is usually nonadjustable. When TC does not match the interaction between the patient's inspiratory-expiratory efforts to the opening and closing of the inspiratory and expiratory valves, patient...

journal_title：Anesthesia and analgesia

authors： Tokioka H,Tanaka T,Ishizu T,Fukushima T,Iwaki T,Nakamura Y,Kosogabe Y

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Unanticipated hospital admission is regarded as a measure of adverse perioperative patient care. However, previously published studies for risk prediction after ambulatory procedures are sparse compared to those examining readmission after inpatient surgery. We aimed to evaluate the incidence and reasons for...

journal_title：Anesthesia and analgesia

authors： Teja B,Raub D,Friedrich S,Rostin P,Patrocínio MD,Schneider JC,Shen C,Brat GA,Houle TT,Yeh RW,Eikermann M

更新日期：2020-08-01 00:00:00