Clonidine decreases plasma catecholamines and improves outcome from incomplete ischemia in the rat.

abstract：UNLABELLED:Incorrect positioning of central venous catheters (CVC) in infants and children may lead to serious complications such as perforation of the heart or great vessels. CVC position is not usually assessed until the first postoperative chest radiograph, potentially leaving malposition undetected for several hour...

journal_title：Anesthesia and analgesia

authors： Andropoulos DB,Bent ST,Skjonsby B,Stayer SA

更新日期：2001-10-01 00:00:00

abstract：UNLABELLED:When opioids are used for postoperative pain control, it is useful to define the dose-response relationship for analgesia and respiratory depression. We studied 20 chronically opioid-consuming patients having elective multilevel spine fusion. Preoperatively, each patient received a fentanyl infusion of 2 mic...

journal_title：Anesthesia and analgesia

authors： Davis JJ,Swenson JD,Hall RH,Dillon JD,Johnson KB,Egan TD,Pace NL,Niu SY

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Ten to fifteen percent of awake patients develop neurological deficits secondary to cerebral hypoperfusion after carotid artery cross-clamping. The reversal of such deficits by increasing the inspired oxygen fraction (Fio(2)) has been demonstrated, and regional cerebral oxygenation (rSO(2)) has been shown to...

journal_title：Anesthesia and analgesia

authors： Picton P,Chambers J,Shanks A,Dorje P

更新日期：2010-02-01 00:00:00

abstract：:The ideal choice of a priming solution of the cardiopulmonary bypass (CPB) and its influence on the hemostatic system are not clear. Addition of albumin was reported to inhibit platelet damaging by blood-surface interactions ("coating"). To explore this possibility in 60 consecutive male patients undergoing elective a...

journal_title：Anesthesia and analgesia

authors： Boldt J,Zickmann B,Ballesteros BM,Stertmann F,Hempelmann G

更新日期：1992-02-01 00:00:00

abstract：:Cardiopulmonary bypass (CPB) impairs pulmonary endothelial injury in part by increasing expression of adhesion molecules that results in neutrophil influx. Although numerous proinflammatory cytokines up-regulate these responses, the extent to which systemic and pulmonary proinflammatory cytokines increase remains unkn...

journal_title：Anesthesia and analgesia

authors： Kotani N,Hashimoto H,Sessler DI,Muraoka M,Wang JS,O'Connor MF,Matsuki A

更新日期：2000-05-01 00:00:00

abstract：UNLABELLED:The most effective group of drugs for the treatment of severe pain is opioid analgesics. Their use, however, is limited by decreased effects in neuropathic and chronic pain as a result of increased pain and development of tolerance. Gabapentin (GBP) is effective in both experimental models of chronic pain an...

journal_title：Anesthesia and analgesia

authors： Eckhardt K,Ammon S,Hofmann U,Riebe A,Gugeler N,Mikus G

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:We evaluated the interaction of dopamine-proxymetacaine and dopamine- oxybuprocaine antinociception using isobolograms. METHODS:This experiment uses subcutaneous drug (proxymetacaine, oxybuprocaine, and dopamine) injections under the skin of the rat's back, thus simulating infiltration blocks. The dose-rela...

journal_title：Anesthesia and analgesia

authors： Chen YW,Chiu CC,Lin HT,Wang JJ,Hung CH

更新日期：2018-05-01 00:00:00

abstract：:A guinea pig model of halothane hepatitis was used to explore the humoral immune response induced by multiple halothane exposures and the potential role this response might play in contributing to liver damage. Three different strains of guinea pigs (Strain 2, Amana, and Hartley) were exposed to 1% halothane under eit...

journal_title：Anesthesia and analgesia

authors： Siadat-Pajouh M,Hubbard AK,Roth TP,Gandolfi AJ

更新日期：1987-12-01 00:00:00

abstract：:Electroconvulsive therapy (ECT) is a highly effective treatment for severe depression. However, its use is associated with significant posttreatment cognitive impairment. Magnetic seizure therapy (MST) was developed as an alternative therapy that could reduce postseizure side effects through the induction of more "foc...

journal_title：Anesthesia and analgesia

authors： White PF,Amos Q,Zhang Y,Stool L,Husain MM,Thornton L,Downing M,McClintock S,Lisanby SH

更新日期：2006-07-01 00:00:00

abstract：:Epidural anesthesia may be performed as a single injection or by staged doses. Thirty patients undergoing primary total hip replacement were randomly assigned to have epidural anesthesia using a single injection or a staged technique with 25 mL of 0.75% bupivacaine. Arterial plasma bupivacaine concentrations were sign...

journal_title：Anesthesia and analgesia

authors： Sharrock NE,Mineo R,Stanton J,Ennis WJ 3rd,Urmey WF,Arthur GR

更新日期：1994-08-01 00:00:00

abstract：:Malignant hyperthermia syndrome associated with various anesthetic agents has been well documented, but none has been reported with enflurane (Ethrane). This particular case is the first involving exposure for the second time to enflurane anesthesia after a six-month interval in which malignant hyperthermia resulted. ...

journal_title：Anesthesia and analgesia

authors： Pan TH,Wollack AR,DeMarco JA

更新日期：1975-01-01 00:00:00

abstract：:Under halothane anesthesia five dogs were prepared with both hindlimbs isolated from the systemic circulation to allow intermittent placement on extracorporeal perfusion at constant flow. One limb of each dog was surgically denervated. In this relatively anesthetic-free preparation, graded equivalent doses of alfentan...

journal_title：Anesthesia and analgesia

authors： White DA,Reitan JA,Kien ND,Thorup SJ

更新日期：1990-07-01 00:00:00

abstract：UNLABELLED:Neuronal baseline K(+) channels were activated by several volatile anesthetics. Whole-cell recordings from cultured cerebellar granule neurons of 7-day-old male Sprague-Dawley rats showed outward-rectifying K(+) currents with a conductance of approximately 1.1 +/- 0.3 nS (n = 20) at positive potentials. The ...

journal_title：Anesthesia and analgesia

authors： Shin WJ,Winegar BD

更新日期：2003-05-01 00:00:00

abstract：:Multiple logistic regression studies frequently are performed with duration (e.g., operative time) included as an independent variable. We use narrative review of the statistical literature to highlight that when the association between duration and outcome is presumptively significant, the procedure itself (e.g., vid...

journal_title：Anesthesia and analgesia

authors： Dexter F,Dexter EU,Ledolter J

更新日期：2011-11-01 00:00:00

abstract：:We studied the effect of halothane on the fetal cardiovascular system of six lambs in utero by measuring fetal heart rate and femoral arterial blood pressure and by injecting labeled microspheres during a control period and again after 60 and 90 min of halothane anesthesia administered to six pregnant ewes at an inspi...

journal_title：Anesthesia and analgesia

authors： Biehl DR,Tweed WA,Cote J,Wade JG,Sitar D

更新日期：1983-05-01 00:00:00

abstract：:In Japan, an ever-present problem in the preoperative evaluation of patients with ischemic heart disease is that although such evaluations are based on Western data, these data serve as the basis for determining perioperative risk in Japanese patients. To remedy this problem, the Cardiac Ischemia and Anesthesia Resear...

journal_title：Anesthesia and analgesia

authors： Seki M,Kashimoto S,Nagata O,Yoshioka H,Ishiguro T,Nishimura K,Honda O,Sakamoto A,Omi A,Ogihara Y,Fujimoto K,Iwade M,Yamada T,Nomura M,Takeda J

更新日期：2005-05-01 00:00:00

abstract：:High blood concentrations of local anesthetics are cardiotoxic. The aim of this study was to compare the effects of lidocaine and bupivacaine on the intrinsic pacemaker activity of in vitro sinoatrial nodal cells of the adult and neonatal guinea pig in the presence and absence of hypoxia and acidosis. Fifteen pairs of...

journal_title：Anesthesia and analgesia

authors： Bosnjak ZJ,Stowe DF,Kampine JP

更新日期：1986-09-01 00:00:00

abstract：UNLABELLED:The effect of opioid administration on the bispectral index (BIS) during general anesthesia is controversial. Several investigators have reported BIS to be insensitive to opioid addition, whereas others have found a hypnotic response. We designed this study to examine the effect of remifentanil on BIS during...

journal_title：Anesthesia and analgesia

authors： Koitabashi T,Johansen JW,Sebel PS

更新日期：2002-06-01 00:00:00

abstract：UNLABELLED:Propofol and alfentanil are both rapid and short-acting drugs that can be used for sedation and analgesia during monitored anesthesia care (MAC). This study was designed to determine the optimal infusion rates of propofol and alfentanil when administered during local anesthesia. In this randomized, double-bl...

journal_title：Anesthesia and analgesia

authors： Avramov MN,White PF

更新日期：1997-09-01 00:00:00

abstract：:Response time (RT) of the Narkotest anesthetic gas monitor was measured for 7 inhalation anesthetics, using a 5 L/min fresh gas flow (FGF). Time to 63 percent of maximum response (RT63) and to 95 percent of maximum response (RT95) was directly related to rubber/gas and oil/gas partition coefficients. RT95 ranged from ...

journal_title：Anesthesia and analgesia

authors： Velazquez JL,Feingold A,Walther P

更新日期：1977-05-01 00:00:00

abstract：:Patient-reported outcomes (PROs) are measures of health status that come directly from the patient. PROs are an underutilized tool in the perioperative setting. Enhanced recovery pathways (ERPs) have primarily focused on traditional measures of health care quality such as complications and hospital length of stay. The...

journal_title：Anesthesia and analgesia

authors： Abola RE,Bennett-Guerrero E,Kent ML,Feldman LS,Fiore JF Jr,Shaw AD,Thacker JKM,Gan TJ,Miller TE,Hedrick TL,McEvoy MD,Mythen MG,Bergamaschi R,Gupta R,Holubar SD,Senagore AJ,Wischmeyer PE,Carli F,Evans DC,Guilbert S,

更新日期：2018-06-01 00:00:00

abstract：UNLABELLED:Patients may have concerns about their ability to manage postoperative symptoms at home after ambulatory surgery. We assessed patients' attitudes toward postoperative care at home or in the hospital after laparoscopic cholecystectomy. Thirty-eight patients undergoing elective laparoscopic cholecystectomy wer...

journal_title：Anesthesia and analgesia

authors： Lehmann HP,Fleisher LA,Lam J,Frink BA,Bass EB

更新日期：1999-06-01 00:00:00

abstract：:Fetal cocaine exposure has been associated with a variety of cardiovascular dysfunctions in humans. We treated pregnant rats with either saline or cocaine at 60 mg/kg by gastric lavage for the entire gestational period and for 14 days after parturition. We then performed high-frequency transthoracic echocardiography t...

journal_title：Anesthesia and analgesia

authors： Sun LS,Takuma S,Lui R,Homma S

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:A lighted stylet is an effective alternative to a direct laryngoscope and has been reported to be particularly useful in patients with difficult airways. A high Mallampati class indicates poor visibility of the oropharyngeal structures. Because a lighted stylet does not require direct oropharyngeal visualiza...

journal_title：Anesthesia and analgesia

authors： Rhee KY,Lee JR,Kim J,Park S,Kwon WK,Han S

更新日期：2009-04-01 00:00:00

abstract：UNLABELLED:New neurological deficit after spinal surgery is a rare complication that requires a quick diagnostic and therapeutic approach to reduce the risk of permanent neurological disabilities. We report a patient who presented with transient neurologic deficit after surgery for lumbar disk herniation resulting from...

journal_title：Anesthesia and analgesia

authors： Hernández-Palazón J,Falcón-Araña LF,García-Martínez M

更新日期：2003-11-01 00:00:00

abstract：:The purpose of this study was to characterize the pharmacodynamics and pharmacokinetics of three concentrations of the new long-acting amide local anesthetic, ropivacaine, given epidurally in 15 physical status ASA I or II patients for elective lower-extremity orthopedic procedures using a nonrandomized open-label des...

journal_title：Anesthesia and analgesia

authors： Katz JA,Bridenbaugh PO,Knarr DC,Helton SH,Denson DD

更新日期：1990-01-01 00:00:00

abstract：:Myocardial injury after noncardiac surgery (MINS) differs from myocardial infarction in being defined by troponin elevation apparently from cardiac ischemia with or without signs and symptoms. Such myocardial injury is common, silent, and strongly associated with mortality. MINS is usually asymptomatic and only detect...

journal_title：Anesthesia and analgesia

authors： Ruetzler K,Khanna AK,Sessler DI

更新日期：2020-07-01 00:00:00

abstract：IMPLICATIONS:Misplacement of an epidural catheter into the subarachnoid space is a recognized complication. However, breakage of an intrathecal epidural catheter during removal presents a dilemma. Appropriate imaging, a neurosurgical consultation, and aggressive surgical exploration and extraction of the retained piece...

journal_title：Anesthesia and analgesia

authors： Ugboma S,Au-Truong X,Kranzler LI,Rifai SH,Joseph NJ,Salem MR

更新日期：2002-10-01 00:00:00

abstract：:There are limited and conflicting data on how a confirmatory step using high-dose heparin can improve diagnostic specificity of the antiplatelet factor 4/heparin enzyme immunoassay for heparin-induced thrombocytopenia (HIT). We investigated sera from a recently published study on cardiac surgery patients and found tha...

journal_title：Anesthesia and analgesia

authors： Selleng S,Schreier N,Wollert HG,Greinacher A

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:The accurate measurement of oxygen consumption (VO2) and energy expenditure (EE) may be helpful to optimize the treatment of critically ill patients. However, current techniques are limited in their ability to accurately quantify these end points in infants due to a low VO2, low tidal volume, and rapid respi...

journal_title：Anesthesia and analgesia

authors： Nachman E,Clemensen P,Santos K,Cole AR,Polizzotti BD,Hofmann G,Leeman KT,van den Bosch SJ,Kheir JN

更新日期：2018-07-01 00:00:00