Adjuvant Bisphosphonates and Breast Cancer Survival.

Abstract:

:Randomized trials have studied bisphosphonates in the adjuvant setting of early breast cancer to investigate their ability to prevent treatment-induced bone loss. Trial results have also suggested their potential to prevent disease recurrence and metastases. These trials are summarized in this review. A recent patient-level meta-analysis by the Early Breast Cancer Trialists' Collaborative Group (EBCTCG) finds convincing evidence that adjuvant antiresorptive treatments provide persistent benefits to breast cancer patients in low-estrogen situations and should be considered an important part of the treatment algorithm.

journal_name

Annu Rev Med

authors

Strobl S,Korkmaz B,Devyatko Y,Schuetz M,Exner R,Dubsky PC,Jakesz R,Gnant M

doi

10.1146/annurev-med-053014-103600

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

1-10

eissn

0066-4219

issn

1545-326X

journal_volume

67

pub_type

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