Electrophysiologic studies in patients with ventricular tachycardia.

abstract：:Over the past several years a combination of diverse steps has culminated in a significant improvement in our ability to save ischemic extremities. Encompassing all phases of vascular surgery, these advances in diagnosis, therapy, and long-term management are outlined. These and future improvements hold promise for ex...

journal_title：Annual review of medicine

authors： Abbott WM,Meier GH

更新日期：1987-01-01 00:00:00

abstract：:An effective host response to infection or tissue damage requires focal accumulation of leukocytes. Leukocyte adhesion to the vessel wall, a key step in this process, depends on the ordered expression of specific endothelial cell surface molecules. The endothelial molecules that support adhesion include selectins that...

journal_title：Annual review of medicine

authors： Bevilacqua MP,Nelson RM,Mannori G,Cecconi O

更新日期：1994-01-01 00:00:00

abstract：:In 2012, a zoonotic coronavirus was identified as the causative agent of Middle East respiratory syndrome and was named MERS coronavirus (MERS-CoV). As of August 11, 2016, the virus has infected 1,791 patients, with a mortality rate of 35.6%. Although MERS-CoV generally causes subclinical or mild disease, infection ca...

journal_title：Annual review of medicine

authors： Fehr AR,Channappanavar R,Perlman S

更新日期：2017-01-14 00:00:00

abstract：:Our understanding and treatment of chronic myelogenous leukemia (CML) has progressed since 1960 in parallel with work on cancer in general. CML provided the first evidence of a specific genetic change associated with a human cancer (the Philadelphia chromosome) and the clonal nature of these disorders. With improved c...

journal_title：Annual review of medicine

authors： Nowell PC

更新日期：2002-01-01 00:00:00

abstract：:The National Diabetes Data Group and the World Health Organization recently made recommendations concerning the classification of diabetes mellitus and proposed new diagnostic criteria. These recommendations are summarized and their bases elucidated. Certain discrepancies between the recommendations are apparent and t...

journal_title：Annual review of medicine

authors： Bennett PH

更新日期：1983-01-01 00:00:00

abstract：:Obesity is perhaps the most significant public health problem facing the United States today. Obese patients are at increased risk for numerous medical problems, which can adversely affect surgical outcome. However, these risks have not uniformly translated into increased or prohibitive operative morbidity and mortali...

journal_title：Annual review of medicine

authors： Flancbaum L,Choban PS

更新日期：1998-01-01 00:00:00

abstract：:Advances in our knowledge of the physiology of pain transmission and modulation have created new surgical options for the control of chronic pain. The pain modulation network can be activated by administration of spinal opiates or by electrical stimulation of the nervous system with transcutaneous, peripheral nerve, s...

journal_title：Annual review of medicine

authors： Landau B,Levy RM

更新日期：1993-01-01 00:00:00

abstract：:Infantile autism probably has many etiologies. Several specific genetic disorders appear to be associated with the syndrome much more often than would be expected by chance, but these account for only a minority of cases. In the majority of cases, where etiology is still unknown, genetic factors probably also play a r...

journal_title：Annual review of medicine

authors： Folstein SE

更新日期：1985-01-01 00:00:00

abstract：:Proteinuric chronic kidney disease (CKD), once a rare affliction believed to be mainly caused by genetic mutations, has become a global pandemic that severely diminishes the quality of life for millions. Despite the changing face of CKD, treatment options and resources remain woefully antiquated and have failed to arr...

journal_title：Annual review of medicine

authors： Reiser J,Sever S

更新日期：2013-01-01 00:00:00

abstract：:The incidence of esophageal adenocarcinoma (EAC) has risen dramatically over the past three decades in western countries. The importance of Barrett's esophagus (BE) derives from its potential to transform to adenocarcinoma. BE is characterized by endoscopically recognized displacement of the squamocolumnar junction pr...

journal_title：Annual review of medicine

authors： Bresalier RS

更新日期：2009-01-01 00:00:00

abstract：:Implantable cardiac pacing and defibrillation devices are effective and commonly used therapies for patients with cardiac rhythm disorders. Because device implantation is not easily reversible, as well as the high healthcare costs inherent in device use, a clear understanding of the clinical benefits relative to costs...

journal_title：Annual review of medicine

authors： Groeneveld PW,Dixit S

更新日期：2017-01-14 00:00:00

abstract：:1. Patients should be divided preoperatively into low- or high-risk categories, depending on their probability of developing postoperative pulmonary complications. The evaluation should include spirometry as well as an assessment of the previously defined risk factors. 2. Patients in a low-risk category need only inst...

journal_title：Annual review of medicine

authors： Pierce AK,Robertson J

更新日期：1977-01-01 00:00:00

abstract：:States of hypersecretion of PTH may occur primarily, or in response to other physiologic abnormalities. Primary hyperparathyroidism must be considered in the differential diagnosis of hypercalcemia, nephrolithiasis, metabolic bone disease, and pancreatitis and peptic-ulcer disease. The clinical manifestations of this ...

journal_title：Annual review of medicine

authors： Bone HG 3rd,Snyder WH 3rd,Pak CY

更新日期：1977-01-01 00:00:00

abstract：:Brain imaging is increasingly applied in psychiatry, both for clinical evaluation and as a research tool. Computerized tomography (CT) and magnetic resonance imaging (MRI) have documented that structural brain abnormalities occur in some types of psychiatric patients, particularly those who suffer from schizophrenia. ...

journal_title：Annual review of medicine

authors： Andreasen NC

更新日期：1988-01-01 00:00:00

abstract：:Alzheimer's disease (AD) is unique in medicine in that millions of people suffer from what appears to be the same form of disease, and unlike most other late-onset diseases, the genetic etiologies have been well identified. Three early onset forms of AD inherited as autosomal dominant traits account for less than 2% o...

journal_title：Annual review of medicine

authors： Roses AD

更新日期：1996-01-01 00:00:00

abstract：:CCR5 antagonists inhibit HIV-1 entry by blocking the interaction of HIV-1 with the CCR5 cellular receptor. In patients with established HIV-1 infection, some viral strains use an alternative coreceptor for HIV-1 entry, CXCR4; CCR5 antagonists are not effective in patients harboring these viral strains. Coreceptor trop...

journal_title：Annual review of medicine

authors： Wilkin TJ,Gulick RM

更新日期：2012-01-01 00:00:00

abstract：:Complementary and alternative medicine (CAM) consists of diverse clinical interventions that are practiced because of their popularity rather than the prior demonstration of safety and efficacy required for conventional agents. CAM therapies can be grouped into five categories: biologically based therapies, manipulati...

journal_title：Annual review of medicine

authors： Berman JD,Straus SE

更新日期：2004-01-01 00:00:00

abstract：:Cyclosporine-A is primary therapy for organ transplantation. Its immunosuppressive effect might suggest a therapeutic role in autoimmune diseases, including several idiopathic and secondary glomerular conditions. Various forms of idiopathic nephrotic syndrome, including focal segmental glomerulosclerosis (FSGS), minim...

journal_title：Annual review of medicine

authors： Klein M,Radhakrishnan J,Appel G

更新日期：1999-01-01 00:00:00

abstract：:MicroRNAs (miRNAs) are small, noncoding RNAs with important functions in development, cell differentiation, and regulation of cell cycle and apoptosis. MiRNA expression is deregulated in cancer by a variety of mechanisms including amplification, deletion, mutation, and epigenetic silencing. Several studies have now sh...

journal_title：Annual review of medicine

authors： Garzon R,Calin GA,Croce CM

更新日期：2009-01-01 00:00:00

abstract：:Acute myocardial infarction is caused by coronary thrombosis on an ulcerated atheroma. We now believe that the predominant cause of this intimal disruption is the rupture of the atheroma through the intimal surface, caused by enzymes released by activated macrophages. The subsequent clinical course following atheroma ...

journal_title：Annual review of medicine

authors： Forrester JS,Litvack F,Grundfest W

更新日期：1991-01-01 00:00:00

abstract：:Cardiac resynchronization therapy (CRT) is well established as a treatment for patients with moderate to severe heart failure on optimal medical therapy. Early studies demonstrated improved functional capacity and evidence of reverse remodeling; more recently, CRT has been associated with a survival benefit in advance...

journal_title：Annual review of medicine

authors： Hasan A,Abraham WT

更新日期：2007-01-01 00:00:00

abstract：:Catastrophic antiphospholipid syndrome (CAPS) is a potentially lethal disease that presents with rapidly progressive multiple organ thromboses. Anticoagulation, corticosteroids, intravenous immunoglobulin, and plasma exchange are the most commonly used treatments for CAPS patients. However, the high mortality despite ...

journal_title：Annual review of medicine

authors： Unlu O,Erkan D

更新日期：2017-01-14 00:00:00

abstract：:Syncope is a common clinical problem comprising the sudden loss of both consciousness and postural tone, with a subsequent spontaneous and relatively prompt recovery. Often it is difficult to differentiate a true syncopal spell from other conditions, such as seizure disorders, or from some simple accidents. Even more ...

journal_title：Annual review of medicine

authors： Benditt DG,Remole S,Milstein S,Bailin S

更新日期：1992-01-01 00:00:00

abstract：:The calcium antagonists are an exciting "class" of drugs that are already making an important impact in the treatment of coronary artery disease. All three drugs in use in the US, verapamil, nifedipine, and diltiazem, are effective coronary vasodilators. In addition, verapamil and diltiazem have antiarrhythmic activit...

journal_title：Annual review of medicine

authors： Schwartz A,Triggle DJ

更新日期：1984-01-01 00:00:00

abstract：:The International HapMap Project produced a genome-wide database of human genetic variation for use in genetic association studies of common diseases. The initial output of these studies has been overwhelming, with over 150 risk loci identified in studies of more than 60 common diseases and traits. These associations ...

journal_title：Annual review of medicine

authors： Manolio TA,Collins FS

更新日期：2009-01-01 00:00:00

abstract：:Ketamine is the prototype for a new generation of glutamate-based antidepressants that rapidly alleviate depression within hours of treatment. Over the past decade, there has been replicated evidence demonstrating the rapid and potent antidepressant effects of ketamine in treatment-resistant depression. Moreover, prec...

journal_title：Annual review of medicine

authors： Abdallah CG,Sanacora G,Duman RS,Krystal JH

更新日期：2015-01-01 00:00:00

abstract：:Fecal microbiota transplantation (FMT) is a well-established treatment for recurrent Clostridioides difficile infection. FMT has become a more readily available and useful new treatment option as a result of stool banks. The current state of knowledge indicates that dysbiosis of the gut microbiota is implicated in sev...

journal_title：Annual review of medicine

authors： Ooijevaar RE,Terveer EM,Verspaget HW,Kuijper EJ,Keller JJ

更新日期：2019-01-27 00:00:00

abstract：:The primary or hereditary form of distal renal tubular acidosis (dRTA), although rare, has received increased attention recently because of dramatic advances in the understanding of its genetic basis. The final regulation of renal acid excretion is effected by various acid/base transporters localized in specialized ce...

journal_title：Annual review of medicine

authors： Batlle D,Ghanekar H,Jain S,Mitra A

更新日期：2001-01-01 00:00:00

abstract：:Most ventricular tachycardias encountered in clinical practice occur in patients who have structural heart disease. Idiopathic ventricular tachycardia refers to those arrhythmias that occur in patients without structural heart disease, metabolic/electrolyte abnormalities, or the long QT syndrome. Three commonly recogn...

journal_title：Annual review of medicine

authors： Altemose GT,Buxton AE

更新日期：1999-01-01 00:00:00

abstract：:Both genetic and environmental factors contribute to the etiology of non-insulin-dependent diabetes. The genetic component is heterogeneous and in some patients is probably complex, involving multiple genes. Specific genetic defects have been identified for rate monogenic forms of NIDDM: maturity-onset diabetes of the...

journal_title：Annual review of medicine

authors： Kahn CR,Vicent D,Doria A

更新日期：1996-01-01 00:00:00