Modeling Clinical States and Metabolic Rhythms in Bioarcheology.

abstract：:We evaluated single nucleotide polymorphism (SNP) detection via a target-capture, C-probe ligation, and RAM assay in a single-blind comparison to clinical samples that had been tested with FDA-cleared tests for up to 4 different vascular disease-related SNPs. In the RAM assay circulizable linear probes (C- or padlock ...

journal_title：BioMed research international

authors： Smith JH,Cui M,Zhang DY,Beals TP,Ye F

更新日期：2014-01-01 00:00:00

abstract：:More than one-third of the world's population is infected with one or more helminthic parasites. Helminth infections are prevalent throughout tropical and subtropical regions where malaria pathogens are transmitted. Malaria is the most widespread and deadliest parasitic disease. The severity of the disease is strongly...

journal_title：BioMed research international

authors： Salazar-Castañon VH,Legorreta-Herrera M,Rodriguez-Sosa M

更新日期：2014-01-01 00:00:00

abstract：:The most frequently seen types of tremor are essential (ET) and parkinsonian tremor (PT) and in some patients clinical characteristics of these tremor types overlap. It is vital to distinguish between these two types of tremor in order to reach the right diagnosis and select the appropriate treatment. One of the widel...

journal_title：BioMed research international

authors： Kragelj V,Georgiev D,Pirtošek Z,Ribarič S

更新日期：2014-01-01 00:00:00

abstract：:The microbial resistance of fungi and bacteria is currently considered a major public health problem. Esters derived from cinnamic acid have a broad spectrum of pharmacological properties that include antimicrobial activity. In this study, a collection of structurally related 4-chlorocinnamic acid esters was prepared ...

journal_title：BioMed research international

authors： Silva RHN,Andrade ACM,Nóbrega DF,de Castro RD,Pessôa HLF,Rani N,de Sousa DP

更新日期：2019-04-23 00:00:00

abstract：:Cancer treatment is undergoing a significant revolution from "one-size-fits-all" cytotoxic therapies to tailored approaches that precisely target molecular alterations. Precision strategies for drug development and patient stratification, based on the molecular features of tumors, are the next logical step in a long h...

journal_title：BioMed research international

authors： Coyle KM,Boudreau JE,Marcato P

更新日期：2017-01-01 00:00:00

abstract：:Long-term application and extensive use of synthetic insecticides have resulted in accumulating their residues in food, milk, water, and soil and cause adverse health effects to human and ecosystems. Therefore, application of natural insecticides in agriculture and public health sectors has been increased as alternati...

journal_title：BioMed research international

authors： Mossa AH,Mohafrash SMM,Chandrasekaran N

更新日期：2018-10-16 00:00:00

abstract：Purpose:It is well known that interstitial photodynamic therapy (iPDT) of large tumors requires effective planning to ensure efficient delivery of therapeutic dose to the target tumors. This should be achieved in parallel with minimal damage to the nearby intact tissues. To that end, clinical iPDT can be attained using...

journal_title：BioMed research international

authors： Ismael FS,Amasha H,Bachir W

更新日期：2020-03-23 00:00:00

abstract：:Aim. The aim of this study was to describe PCa characteristics and long-term outcomes in young men aged ≤55 years after radical prostatectomy (RP) and to compare them with older men cohort. Methods. Among 2,200 patients who underwent RP for clinically localized PCa at our centre between 2001 and 2015, 277 (10.3%) men ...

journal_title：BioMed research international

authors： Milonas D,Venclovas Z,Gudinaviciene I,Zviniene K,Matjosaitis AJ

更新日期：2017-01-01 00:00:00

abstract：:Viral infections result in millions of deaths in the world today. A thorough analysis of virus-host interactomes may reveal insights into viral infection and pathogenic strategies. In this study, we presented a landscape of virus-host interactomes based on protein domain interaction. Compared to the analysis at protei...

journal_title：BioMed research international

authors： Zheng LL,Li C,Ping J,Zhou Y,Li Y,Hao P

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:There are some theoretical concerns for the use of intraoperative cell salvage (ICS) in patients with ectopic pregnancy. This study aimed to observe the impact of ICS on the coagulation function and clinical outcomes of patients with ruptured ectopic pregnancy and severe blood loss. METHODS:This was a retro...

journal_title：BioMed research international

authors： Huang J,Qin D,Gu C,Huang Y,Ma H,Huang H,Huang F,Ruan J,Ling M

更新日期：2017-01-01 00:00:00

abstract：:T-cell acute lymphoblastic leukemia (T-ALL) is a complex disease, resulting from proliferation of differentially arrested immature T cells. The molecular mechanisms and the genes involved in the generation of T-ALL remain largely undefined. In this study, we propose a set of genes to differentiate individuals with T-A...

journal_title：BioMed research international

authors： Maiorov EG,Keskin O,Ng OH,Ozbek U,Gursoy A

更新日期：2013-01-01 00:00:00

abstract：:Liquid and solid samples from two wastewater treatment plants (WWTPs) on Gran Canaria Island (Spain) have been tested for the presence of compounds with endocrine-disrupting properties. The selected degradation stages were sampled bimonthly from each WWTP over the 12-month period from July 2010 to July 2011. The analy...

journal_title：BioMed research international

authors： Vega-Morales T,Sosa-Ferrera Z,Santana-Rodríguez JJ

更新日期：2013-01-01 00:00:00

abstract：:The intra- and extracellular accumulation of misfolded and aggregated amyloid proteins is a common feature in several neurodegenerative diseases, which is thought to play a major role in disease severity and progression. The principal machineries maintaining proteostasis are the ubiquitin proteasomal and lysosomal aut...

journal_title：BioMed research international

authors： Maiti P,Manna J,Veleri S,Frautschy S

更新日期：2014-01-01 00:00:00

abstract：:Background. Monitoring the epidemiology of cardiovascular risk factors (CRFs) and their determinants is important to develop appropriate recommendations to prevent cardiovascular diseases in specific risk groups. The NESCaV study was designed to collect standardized data to estimate the prevalence of CRFs in relation ...

journal_title：BioMed research international

authors： Streel S,Donneau AF,Hoge A,Majerus S,Kolh P,Chapelle JP,Albert A,Guillaume M

更新日期：2015-01-01 00:00:00

abstract：:Salinity is a major environmental stress that limits crop production worldwide. In this study, we characterized plant growth-promoting rhizobacteria (PGPR) containing 1-aminocyclopropane-1-carboxylate (ACC) deaminase and examined their effect on salinity stress tolerance in okra through the induction of ROS-scavenging...

journal_title：BioMed research international

authors： Habib SH,Kausar H,Saud HM

更新日期：2016-01-01 00:00:00

abstract：:Uterine fibroids (UFs) are benign tumors of the reproductive tract, arising from smooth muscle cells of the uterus. Steroid hormones, estrogen, and progesterone are considered to be the most important links in the pathophysiology of UFs. Alpha-tocopherol (AT) is the most active form of vitamin E. What is important as ...

journal_title：BioMed research international

authors： Ciebiera M,Szymańska-Majchrzak J,Sentkowska A,Kilian K,Rogulski Z,Nowicka G,Jakiel G,Tomaszewski P,Włodarczyk M

更新日期：2018-07-24 00:00:00

abstract：Background:Previous studies have investigated the association between the use of bisphosphonates and the development of breast cancer, which presented controversial results. Thus, this meta-analysis was conducted to summarize the current evidence of the association of bisphosphonate use with breast cancer risk. Method...

journal_title：BioMed research international

authors： Peng R,Liang X,Zhang G,Yao Y,Chen Z,Pan X,Wang J,Liu G

更新日期：2020-10-06 00:00:00

abstract：Purpose:Ischemic ocular disorders may be treated by hypervolemic hemodilution. The presumed therapeutic benefit is based on a volume effect and improved rheological factors. The aim was to investigate the acute effect of intravenous hydroxyethyl starch on retrobulbar hemodynamics in patients with nonarteritic anterior ...

journal_title：BioMed research international

authors： Bienert M,Plange N,Remky A,Arend KO,Kuerten D

更新日期：2018-02-06 00:00:00

abstract：:We use hydrophobic poly(lactic-co-glycolic) acid (PLGA) to encapsulate hydrophilic ofloxacin to form drug loading microspheres. Hyaluronic acid (HA) and polylysine (Pls) were used as internal phase additives to see their influences on the drug loading and releasing. Double emulsion (water-in-oil-in-water) solvent extr...

journal_title：BioMed research international

authors： Wu G,Chen L,Li H,Deng CL,Chen XF

更新日期：2014-01-01 00:00:00

abstract：:Early recovery from muscular injury is crucial for elite athletes. Hyperbaric oxygen therapy (HBOT) has been reported to be beneficial in terms of accelerating cell recovery and tissue repair, which are considered to be helpful for eliminating fatigue and recovering stamina. This study was performed to evaluate the ef...

journal_title：BioMed research international

authors： Chen CY,Chou WY,Ko JY,Lee MS,Wu RW

更新日期：2019-05-29 00:00:00

abstract：:Introduction. NOTCH pathway and TP53 protein are involved in the development of fibrosis and autoimmune disorders, respectively. The aim of this study was to evaluate the role of single nucleotide polymorphisms (SNPs) of NOTCH3 and TP53 genes and serum anti-TP53 antibodies with the susceptibility, clinical subset of s...

journal_title：BioMed research international

authors： Zmorzyński S,Wojcierowska-Litwin M,Kowal M,Michalska-Jakubus M,Styk W,Filip AA,Walecka I,Krasowska D

更新日期：2020-02-25 00:00:00

abstract：:Aging is the principal risk factor for the development of Alzheimer's disease (AD). The hallmarks of AD are accumulation of the amyloid-β peptide 1-42 (Aβ42) and abnormal hyperphosphorylation of Tau (p-Tau) protein in different areas of the brain and, more recently reported, in the visual cortex. Recently, Aβ42 peptid...

journal_title：BioMed research international

authors： Hernández-Zimbrón LF,Perez-Hernández M,Torres-Romero A,Gorostieta-Salas E,Gonzalez-Salinas R,Gulias-Cañizo R,Quiroz-Mercado H,Zenteno E

更新日期：2017-01-01 00:00:00

abstract：:Coronary artery diseases (CAD) and heart failure have high mortality rate in the world, although much progress has been made in this field in last two decades. There is still a clinical need for a novel diagnostic approach and a therapeutic strategy to decrease the incidence of CAD. MicroRNAs (miRNAs) are highly conse...

journal_title：BioMed research international

authors： Nishiguchi T,Imanishi T,Akasaka T

更新日期：2015-01-01 00:00:00

abstract：:Multiple sclerosis (MS) is an inflammatory demyelinating disease of the human central nervous system (CNS). Neurotropic demyelinating strain of MHV (MHV-A59 or its isogenic recombinant strain RSA59) induces MS-like disease in mice mediated by microglia, along with a small population of T cells. The mechanism of demyel...

journal_title：BioMed research international

authors： Kishore A,Kanaujia A,Nag S,Rostami AM,Kenyon LC,Shindler KS,Das Sarma J

更新日期：2013-01-01 00:00:00

abstract：:Study of the probiotic potential of microorganisms isolated from fermented foods has been increasing, especially studies related to lactobacilli. In intestinal models, lactobacilli have demonstrated beneficial properties, such as anti-inflammatory activity and increased antibody production, but the molecular mechanism...

journal_title：BioMed research international

authors： Pessoa WFB,Melgaço ACC,de Almeida ME,Ramos LP,Rezende RP,Romano CC

更新日期：2017-01-01 00:00:00

abstract：:Dengue fever, a reemerging disease, is putting nearly 2.5 billion people at risk worldwide. The number of infections and the geographic extension of dengue fever infection have increased in the past decade. The disease is caused by the dengue virus, a flavivirus that uses mosquitos Aedes sp. as vectors. The disease ha...

journal_title：BioMed research international

authors： De La Guardia C,Lleonart R

更新日期：2014-01-01 00:00:00

abstract：:The use of supplemental oxygen in uncomplicated cesarean deliveries under spinal anesthesia has been thoroughly investigated during recent decades. The aim of this study was to determine the benefits for both mother and infant of administering supplemental, low-dose oxygen via a nasal cannula versus having no suppleme...

journal_title：BioMed research international

authors： Siriussawakul A,Triyasunant N,Nimmannit A,Ngerncham S,Hirunkanokpan P,Luang-Aram S,Pechpaisit N,Wangdee A,Ruangvutilert P

更新日期：2014-01-01 00:00:00

abstract：:The repair of bone defects is a big challenge in reconstructive surgery. Periosteal distraction osteogenesis (PDO), as a promising technique used for bone regeneration, forms a space between the periosteum and bone cortex to regenerate the new bone merely by distracting the periosteum. In order to investigate the infl...

journal_title：BioMed research international

authors： Zhao D,Jiang W,Wang Y,Wang C,Zhang X,Li Q,Han D

更新日期：2020-04-23 00:00:00

abstract：:Tumors and wounds share many similarities including loss of tissue architecture, cell polarity and cell differentiation, aberrant extracellular matrix (ECM) remodeling (Ballard et al., 2006) increased inflammation, angiogenesis, and elevated cell migration and proliferation. Whereas these changes are transient in repa...

journal_title：BioMed research international

authors： Tolg C,McCarthy JB,Yazdani A,Turley EA

更新日期：2014-01-01 00:00:00

abstract：:Previous studies indicated that intracerebroventricular administration of nerve growth factor (NGF) leads to massive Schwann cell hyperplasia surrounding the medulla oblongata and spinal cord. This study was designed to characterize the proliferation of peripheral glial cells, that is, Schwann and satellite cells, in ...

journal_title：BioMed research international

authors： Schlachetzki JC,Pizzo DP,Morrissette DA,Winkler J

更新日期：2014-01-01 00:00:00