Abstract:
PURPOSE:This study aims to identify prognostic factors related to short-term and long-term outcomes of patients with hematological malignancy (HM) admitted to the intensive care unit (ICU) in Japan during ICU stay and after discharge from ICU. METHODS:We conducted a retrospective, observational study of 169 patients with HM admitted to the general ICU from January 2009 to December 2016. We examined prognostic factors affecting outcome during ICU stay and at 180 days after ICU discharge using logistic regression analysis. RESULTS:During ICU stay, 57 patients (33.7%) died. Invasive mechanical ventilation (OR 8.96, 95% CI 3.67-21.9; P < 0.001, the same hereinafter), the Sequential Organ Failure Assessment (SOFA) score within the first 24 h of ICU admission (1.25, 1.11-1.40; P < 0.001), and malignant lymphoma (0.30, 0.11-0.78; P = 0.014) were detected as factors associated with ICU outcome. Of 112 ICU survivors, 46 (41.1%) died within 180 days after ICU discharge. Duration of ICU stay (1.07, 1.01-1.13; P = 0.027) and the SOFA score at ICU discharge (1.24, 1.04-1.48; P = 0.016) were related to poor outcome at 180 days after ICU discharge. CONCLUSIONS:In critically ill patients with HM, the use of invasive mechanical ventilation, a high SOFA score within the first 24 h of ICU admission, and malignant lymphoma as primary HM affected short-term ICU outcome. Increased duration of ICU stay and SOFA score at ICU discharge influenced long-term outcome at 180 days after ICU discharge.
journal_name
J Anesthjournal_title
Journal of anesthesiaauthors
Irie H,Otake T,Kawai K,Hino M,Namazu A,Shinjo Y,Yamashita Sdoi
10.1007/s00540-017-2390-7subject
Has Abstractpub_date
2017-10-01 00:00:00pages
736-743issue
5eissn
0913-8668issn
1438-8359pii
10.1007/s00540-017-2390-7journal_volume
31pub_type
杂志文章abstract:PURPOSE:Newborns are often sedated during MRI but sedation itself creates adverse events and management is more challenging in this environment. Oral glucose/sucrose administration has been studied in newborns during painful procedures; however, its effectiveness in keeping newborns sleepy and motionlessness during pai...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-016-2296-9
更新日期:2017-04-01 00:00:00
abstract::Recently, ultrasound-guided caudal anesthesia has been performed for postoperative pain management after lumbar spine surgery. Although it is well known that intravascular injection often occurs in the caudal part of the spine, and that this cannot be detected at the time of injection under ultrasound screening, the r...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-014-1840-8
更新日期:2014-12-01 00:00:00
abstract:PURPOSE:Malignant hyperthermia (MH) results from disordered calcium (Ca(2+)) homeostasis in skeletal muscle during general anesthesia. Although Ca(2+) channel blockers may be given to treat the tachycardia and circulatory instability, coadministration of Ca(2+) channel blockers and dantrolene is contraindicated during ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-012-1347-0
更新日期:2012-08-01 00:00:00
abstract::It is recommended that the period of fasting before elective surgery should be shortened to facilitate a rapid recovery by preventing catabolism. We examined the effects of a short period of fasting on metabolism by performing indirect calorimetry (IC) under general anesthesia. A prospective observational study involv...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-014-1950-3
更新日期:2015-06-01 00:00:00
abstract:PURPOSE:The present case-control study was conducted to evaluate whether acute normovolemic hemodilution (ANH) can reduce the need for perioperative allogeneic blood transfusion (ABT) and affect the incidence of perioperative complications in free-flap reconstruction of the head and neck. METHODS:This single-center, r...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-019-02714-5
更新日期:2020-04-01 00:00:00
abstract::Cervical spinal cord injury is a rare but serious complication after general anesthesia. The risk factors include traumatic cervical injury, cervical spine instability, and difficult airway management. It has also occurred in the absence of cervical instability. Here we report a patient who had a history of intermitte...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-013-1667-8
更新日期:2014-02-01 00:00:00
abstract:PURPOSE:We evaluated the hemodynamic and respiratory effects of dexmedetomidine in intubated, spontaneously breathing patients after endoscopic submucosal dissection (ESD) for cervical esophageal or pharyngeal cancer. METHODS:This retrospective study included 129 patients aged 66.5 ± 8.3 years, who underwent ESD under...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-016-2175-4
更新日期:2016-08-01 00:00:00
abstract::Although anaphylactoid reactions to local anesthetics are well known, a radioallergosorbent test (RAST) to detect specific drug reagin (IgE) anti-body has not been developed. We established RAST for local anesthetics by using carboxylic acid derivatives of lidocaine, procaine and methylparaben. Serum samples were take...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054090030074
更新日期:1989-03-01 00:00:00
abstract:PURPOSE:The aim of this pilot study was to evaluate the diagnostic value of pleth variability index (PVI) to predict fluid responsiveness in newborn infants during surgery. METHODS:PVI was continuously recorded in 29 mechanically ventilated newborn infants during surgery, and episodes of clinically indicated volume ex...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-012-1511-6
更新日期:2013-04-01 00:00:00
abstract::Perioperative positive airway pressure (PAP) is recommended by the American Society of Anesthesiologists for patients with obstructive sleep apnea, but a readily available and personalized intraoperative delivery system does not exist. We present the successful use of a patient's own nasal PAP machine in the operating...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-016-2188-z
更新日期:2016-08-01 00:00:00
abstract:PURPOSE:Our purpose was to examine the effect of dexmedetomidine, when used with phenylephrine during cardiopulmonary resuscitation (CPR), on the cerebral and systemic circulations. METHODS:In pentobarbital-anesthetized, mechanically ventilated dogs, we evaluated pial vessel diameters, cerebral oxygen extraction, and ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-006-0402-0
更新日期:2006-01-01 00:00:00
abstract:PURPOSE:Increased glucose variability may be associated with worse outcomes in critically ill patients. Hyperinsulinemic normoglycemia provides intensive glucose control during surgery and may reduce glucose variability. Our objective was to compare glycemic variability between two methods of glucose control in cardiac...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-016-2295-x
更新日期:2017-04-01 00:00:00
abstract::Mechanical influences independent of chemoreceptor function on ventilatory control were studied in halothane-anesthetized, artificially ventilated patients using the technique reported by Altose et al. (Respir Physiol 66: 171-180, 1986). Contribution of mechanical factor was indirectly assessed by comparing the values...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054020060387
更新日期:1992-10-01 00:00:00
abstract:PURPOSE:To investigate the differences in recovery of postural stability, after obtaining similar intravenous sedation levels with midazolam, in elderly and younger patients undergoing dental surgery. METHODS:We studied 15 elderly patients (>65 years) and 15 younger patients (<55 years) after intravenous sedation. Mid...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s005400200024
更新日期:2002-01-01 00:00:00
abstract::Tracheomalacia after thyroidectomy is a life-threatening situation. However, it is difficult to predict postoperative tracheal obstruction with certainty. A case of a 74-year-old woman with a long-standing adenomatous goiter (98 g) is reported. She had undergone partial right lobe thyroidectomy 54 years earlier. After...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-011-1181-9
更新日期:2011-10-01 00:00:00
abstract::The direct inotropic action of seven local anesthetics: procaine, mapivacaine, lidocaine, tetracaine, chloroprocaine, bupivacaine and etidocaine were compared in isolated cat papillary muscles. All of the local anesthetics produced a dose-related depression of maximal velocity of shortening (Vmax), maximal developed f...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054000040001
更新日期:1990-01-01 00:00:00
abstract:PURPOSE:The effects of midazolam-thiopental coinduction on recovery were investigated and compared with thiopental induction. METHODS:Fifty patients, ASA 1 or 2, undergoing minor orthopedic surgery, were randomly divided into coinduction and thiopental groups. During preoxygenation, the patients received midazolam 0.1...
journal_title:Journal of anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s005400170044
更新日期:2001-01-01 00:00:00
abstract::The intradiscal high-pressure injection of saline and lidocaine (IDHP) is a minimally invasive percutaneous procedure for a lumbar intervertebral disc extrusion. The purpose of this study was to investigate the clinical outcomes of IDHP in terms of pain relief, reduction of disability, and risk of complications. Thirt...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-012-1419-1
更新日期:2012-10-01 00:00:00
abstract:PURPOSE:Inadvertent hypothermia is a relatively common intraoperative complication. Few studies have investigated predictors of body temperature change or the effect of the blanket type used with a forced-air warming device during the intraoperative period. We investigated the predictive factors of intraoperative body ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-018-2585-6
更新日期:2019-02-01 00:00:00
abstract::The concentrations of placental transfer of halothane (H), enflurane (E), sevoflurane (S), and isoflurane (I) were measured in 46 patients during cesarean section. The mean inhalation times of H (0.5%), E (1%), S (0.8%), and I (0.6%) were 13 min 27 s, 13 min 49s, 13 min 20s, and 8 min 8s, respectively. The mean concen...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02479867
更新日期:1995-09-01 00:00:00
abstract:PURPOSE:Postoperative sore throat (POST) after general anesthesia with endotracheal intubation is a common and undesirable complication. In this study, we evaluated the combined effects of paracetamol and dexamethasone on the prevention of POST in patients after general anesthesia. METHODS:A total of 226 patients sche...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-017-2411-6
更新日期:2017-12-01 00:00:00
abstract:PURPOSE:To elucidate the mechanisms of the more profound hypotensive effects of propofol relative to thiamylal, we monitored changes in left ventricular (LV) preload, afterload, and contractility during the course of anesthetic induction with propofol and thiamylal. METHODS:Thirty-two patients (ASA I) were randomly as...
journal_title:Journal of anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s005400070021
更新日期:2000-01-01 00:00:00
abstract:PURPOSE:For direct laryngoscopy, we compared midline and left-molar approaches with respect to ease of intubation, using a Macintosh blade. We investigated the relationship between failure of the left-molar approach and preoperative risk factors for difficult intubation. METHODS:With local ethics committee approval, 2...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-008-0694-3
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Epidemiologic studies suggest the possibility of a modestly elevated risk of adverse neurodevelopmental outcomes in children exposed to anesthesia during early childhood. Sevoflurane is widely used in pediatric anesthetic practice because of its rapid induction and lower pungency. However, it is reported tha...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-018-2545-1
更新日期:2018-10-01 00:00:00
abstract::The effect of famotidine on neonates was studied in 34 obstetric patients who underwent elective cesarean section. In the famotidine group, 20 mg of famotidine was intramuscularly injected at 60 min before induction of anesthesia, and 0.5 mg of atropine was injected at 30 min before induction. In the control group, on...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054010050276
更新日期:1991-07-01 00:00:00
abstract::Fifteen infants and children (M = 7, F = 8), aged from 0 to 13 years, who underwent cardiac catheterization and cardioangiography under ketamine-diazepam anesthesia were the subjects of this study. The effect of a contrast medium, isolamate sodium (66.8%) on the plasma somolality and vasopressin concentration was stud...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054010050203
更新日期:1991-04-01 00:00:00
abstract:PURPOSE:To study the delivery efficiency of procaterol aerosols administered through the tracheal tube (ETT) with a metered-dose inhaler (MDI) during apnea. METHODS:First, in a normal room air environment (at ambient temperatures of 24 degrees to 26 degrees C), we measured the amount of aerosol delivered through the E...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s005400200044
更新日期:2002-01-01 00:00:00
abstract:PURPOSE:The aim of this study was to determine the hemodynamic and blood gas effects of inhalational anesthetics on the maternal-fetal sheep unit. The principal hypothesis, tested in chronically instrumented near-term pregnant ewes, was that sevoflurane anesthesia may be safe and useful for the mother and fetus during ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-009-0763-2
更新日期:2009-01-01 00:00:00
abstract::We report three cases with systolic anterior motion (SAM) after mitral valve plasty. Preoperative mitral valve morphology is a risk factor for SAM. The morphological characteristics of SAM have been revealed in several studies. We found a small distance between coaptation and the interventricular septum in all cases, ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-013-1731-4
更新日期:2014-06-01 00:00:00
abstract::Cardiac effects of sevoflurane (SE) with or without nitrous oxide were examined in the canine blood-perfused papillary muscle and sinoatrial node preparations. Although SE depressed developed tension (DT), mean arterial pressure (MAP) and heart rate of the donor dog (DHR) dose dependently, sinoatrial rate (SAR) was no...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054090030145
更新日期:1989-09-01 00:00:00