Abstract:
:Cardiac effects of sevoflurane (SE) with or without nitrous oxide were examined in the canine blood-perfused papillary muscle and sinoatrial node preparations. Although SE depressed developed tension (DT), mean arterial pressure (MAP) and heart rate of the donor dog (DHR) dose dependently, sinoatrial rate (SAR) was not changed significantly. No significant changes in MAP, DHR and SAR were observed with the addition of nitrous oxide to SE. However, the addition of nitrous oxide to SE resulted in significant decrease of DT. These results suggest that SE depresses BP and cardiac contractility dose dependently, but dose not change heart rate. The combination of nitrous oxide and SE may produce less cardiovascular depressant effect at a given MAC level than SE given alone.
journal_name
J Anesthjournal_title
Journal of anesthesiaauthors
Manabe M,Ookawa I,Nonaka A,Kumazawa Tdoi
10.1007/s0054090030145subject
Has Abstractpub_date
1989-09-01 00:00:00pages
145-8issue
2eissn
0913-8668issn
1438-8359journal_volume
3pub_type
杂志文章abstract::We present a case of a 33-year-old woman with Kabuki syndrome (KS) presenting with Henoch-Schönlein purpura (HSP). She was admitted to our hospital with a brain abscess in the lateral ventricle and meningitis. She had been diagnosed with KS. Skin eruptions had appeared on her lower extremities, with arthralgia, cough,...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-008-0656-9
更新日期:2008-01-01 00:00:00
abstract::For select total knee arthroplasty (TKA) patients, we have established an alternative pathway to bypass the acute care surgical ward and directly admit patients from the post-anesthesia care unit to on-campus rehabilitation. We retrospectively examined whether this 'fast track' pathway decreased costs and improved pat...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-017-2372-9
更新日期:2017-10-01 00:00:00
abstract::Mechanical influences independent of chemoreceptor function on ventilatory control were studied in halothane-anesthetized, artificially ventilated patients using the technique reported by Altose et al. (Respir Physiol 66: 171-180, 1986). Contribution of mechanical factor was indirectly assessed by comparing the values...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054020060387
更新日期:1992-10-01 00:00:00
abstract::The pharmacokinetics and pharmacodynamics of vecuronium bromide were studied in patients under general anesthesia of enflurane and nitrous oxide in oxygen. Eighteen patients were randomly divided into two groups which received either 0.05 mg.kg(-1) (low dose group) or 0.20 mg.kg(-1) (high dose group) of vecuronium int...
journal_title:Journal of anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s0054020060028
更新日期:1992-01-01 00:00:00
abstract:PURPOSE:Morphine is a powerful analgesic but its effect is often diminished owing to the development of tolerance. It has been suggested that morphine activates microglia through its action on the toll-like receptor 4 (TLR4) in the spinal cord, leading to suppression of the morphine effect. However, it has not been exa...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-012-1469-4
更新日期:2013-02-01 00:00:00
abstract:PURPOSE:Because the safety of intravenous fentanyl patient-controlled analgesia (iv-PCA) administered during labor remains unclear, we retrospectively examined the labor records from January 2005 to December 2007 in our institution, with a focus on both maternal and neonatal outcomes, as compared to no analgesia. METH...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-011-1292-3
更新日期:2012-04-01 00:00:00
abstract::The effect-compartment concentration (C(e)) of a drug at a specific pharmacodynamic endpoint should be independent of the rate of drug injection. We used this assumption to derive an effect-compartment equilibrium rate constant (k(eo)) for propofol during induction of anesthesia, using a target controlled infusion dev...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-005-0378-1
更新日期:2006-01-01 00:00:00
abstract::Optimal visualization of the glottis can be crucial to successful laryngoscopy. Limited information has been published on the light intensity delivered from laryngoscopes powered by rechargeable batteries. In this study the laryngoscope light intensity delivered from 10 nickel metal hydride (NiMH), 7 nickel cadmium (N...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-013-1618-4
更新日期:2013-10-01 00:00:00
abstract:PURPOSE:In order to elucidate the prominent factors involved in intraoperative bradycardia in adult patients, we retrospectively investigated the association between the potential risk factors and intraoperative bradycardia, using multiple logistic regression. METHODS:The perioperative records for 499 adult patients w...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-006-0469-7
更新日期:2007-01-01 00:00:00
abstract:PURPOSE:The effects of midazolam-thiopental coinduction on recovery were investigated and compared with thiopental induction. METHODS:Fifty patients, ASA 1 or 2, undergoing minor orthopedic surgery, were randomly divided into coinduction and thiopental groups. During preoxygenation, the patients received midazolam 0.1...
journal_title:Journal of anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s005400170044
更新日期:2001-01-01 00:00:00
abstract::We report an 83-year-old man with myasthenia gravis (MG) who developed respiratory depression after spinal anesthesia for transurethral laser enucleation of the prostate. He became less responsive after complained of dyspnea, with a decrease of SpO2 to 83% approximately 13 min after intrathecal administration of 0.5% ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-020-02874-9
更新日期:2021-02-01 00:00:00
abstract::This retrospective study aimed to determine whether prophylactic transcutaneous pacing is required for patients with complete right bundle-branch block (CRBBB) and axis deviation (AD), so-called bifascicular block, when surgical procedures are performed under general or local anesthesia. The authors reviewed 34 063 an...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-009-0783-y
更新日期:2009-01-01 00:00:00
abstract::Within the airway management field, simulation has been used as a tool of training for over 40 years. Simulation training offers a chance of active involvement for the trainees. It can effectively enhance and upgrade the knowledge and skills of the trainees in airway management, and subsequently decrease medical error...
journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
doi:10.1007/s00540-015-2116-7
更新日期:2016-04-01 00:00:00
abstract::Cardiac surgery-associated acute kidney injury (AKI) is a major health problem that is extremely common and has a significant effect on cardiac surgical outcomes. AKI occurs in nearly 30 % of patients undergoing cardiac surgery, with about 1-2 % of these ultimately requiring dialysis. The development of AKI predicts a...
journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
doi:10.1007/s00540-012-1523-2
更新日期:2013-06-01 00:00:00
abstract::We report a case of hyperglycemic shock associated with hepatic portal venous gas. A 79-year-old woman with post-stroke depression developed severe tachycardiac atrial fibrillation and hypotension due to hypovolemia caused by severe hyperglycemia, as well as showing disseminated intravascular coagulation (DIC). Contin...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-007-0586-y
更新日期:2008-01-01 00:00:00
abstract:PURPOSE:The use of continuous epidural anesthesia in patients with chronic renal failure is rare and controversial. In this study, we compared the effects of epidural versus general anesthesia on early postoperative renal function in patients who underwent renal transplantation surgery. METHODS:Sixty-eight adult patie...
journal_title:Journal of anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s005400200004
更新日期:2002-01-01 00:00:00
abstract:PURPOSE:Volatile anesthetics affect the cardiovascular and immune systems. Toward a better understanding of the molecular mechanisms behind the modulation exerted by these agents, we focused on the effects of halothane and isoflurane on the activation of p38 mitogen-activated protein kinase (MAPK), which plays a critic...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-004-0237-5
更新日期:2004-01-01 00:00:00
abstract::In a case with malignant hyperthermia (MH), membrane fluidity of erythrocytes was studied by electron spin resonance (ESR)-spin labeling technique. The measurement was made with samples obtained during and after pyrexic crisis until full recovery. The results indicated that membrane fluidity increased during pyrexic c...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054070010088
更新日期:1987-03-01 00:00:00
abstract::The concentrations of placental transfer of halothane (H), enflurane (E), sevoflurane (S), and isoflurane (I) were measured in 46 patients during cesarean section. The mean inhalation times of H (0.5%), E (1%), S (0.8%), and I (0.6%) were 13 min 27 s, 13 min 49s, 13 min 20s, and 8 min 8s, respectively. The mean concen...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02479867
更新日期:1995-09-01 00:00:00
abstract::Beta-adrenergic blockers (β-blockers) are clearly indicated for the long-term treatment of patients with systolic heart failure and post-acute myocardial infarction. Early small-scale studies reported their potential benefits for perioperative use; subsequent randomized controlled trials, however, failed to reproduce ...
journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
doi:10.1007/s00540-019-02691-9
更新日期:2020-02-01 00:00:00
abstract::The relationship between tumor size and the complexity of anesthetic management was studied using several values: plasma catecholamine concentrations, requirement of vasoactive agents, surgical time, blood loss, plasma glucose concentrations, and hemodynamic variables. Ten patients with clinical and laboratory diagnos...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02514621
更新日期:1994-12-01 00:00:00
abstract:BACKGROUND:Postanesthetic shivering can be triggered by surgical stress and several aspects of anesthetic management and is frequently preceded by a decrease in peripheral blood flow due to thermoregulatory vasoconstriction. As perfusion index correlates with peripheral blood flow, we examined whether perioperative per...
journal_title:Journal of anesthesia
pub_type: 临床试验,杂志文章
doi:10.1007/s00540-013-1658-9
更新日期:2014-02-01 00:00:00
abstract::To avoid the risk of R-on-T incident and the unnecessary decrease of cardiac output, we devised an algorithm consisting of six steps for choosing the most appropriate intraoperative pacemaker (PM) mode, which is modified from Heart Rhythm Society and the American Society of Anesthesiologists expert consensus statement...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-020-02878-5
更新日期:2021-02-01 00:00:00
abstract:PURPOSE:We performed a multicenter, randomized, double-blind trial to assess the efficacy and safety of a single, fixed, intravenous dose of palonosetron (0.075 mg) in the treatment of established postoperative nausea and vomiting (PONV). METHODS:Three hundred and eighty-four patients who had at least one risk factors...
journal_title:Journal of anesthesia
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00540-014-1884-9
更新日期:2015-02-01 00:00:00
abstract::The purpose of this study was to determine the mortality rate in 527 critically ill patients with multiple organ failure (MOF), treated in our ICU between August, 1986 and January, 1992, and to compare it with the results obtained in a group of patients studied who had been treated between October, 1978 and July, 1986...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02514648
更新日期:1994-09-01 00:00:00
abstract:PURPOSE:This study aimed to examine the incidence, case fatality rate, and characteristics of perioperative symptomatic pulmonary thromboembolism (PS-PTE) throughout Japan. METHODS:From 2002 to 2011, confidential questionnaires were mailed annually to all Japanese Society of Anesthesiologists-certified training hospit...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-014-1939-y
更新日期:2015-06-01 00:00:00
abstract::Opioid-related postoperative nausea and vomiting should not occur following remifentanil administration because of its relatively short time to elimination. However, studies have indicated that the incidence of postoperative nausea and vomiting associated with remifentanil is similar to that with other opioids. Hence,...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-018-2550-4
更新日期:2018-10-01 00:00:00
abstract::Cervical spinal cord injury is a rare but serious complication after general anesthesia. The risk factors include traumatic cervical injury, cervical spine instability, and difficult airway management. It has also occurred in the absence of cervical instability. Here we report a patient who had a history of intermitte...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-013-1667-8
更新日期:2014-02-01 00:00:00
abstract::Small children are physiologically subject to arterial oxygen desaturation. However, few reports have referred to the risk factors related to postanesthetic hypoxemia and the duration of hypoxemia. The purpose of this study was to clarify these two aspects. Eighty-five ASA physical status I infants and children were i...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054030070016
更新日期:1993-01-01 00:00:00
abstract:PURPOSE:It has been suggested that the different degrees of fade induced by nondepolarizing neuromuscular blocking agents in repetitive muscular contractions may be due to the varying affinities or binding kinetics of presynaptic nicotinic receptors. We compared the degree of fade induced by mivacurium, cisatracurium, ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s005400300024
更新日期:2003-01-01 00:00:00