Abstract:
:The development of novel vaccine candidates against infections with Mycobacterium tuberculosis has highlighted our limited understanding of immune mechanisms required to kill M. tuberculosis. The induction of a Th1 immunity is vital, but new studies are required to identify other mechanisms that may be necessary. Novel vaccines formulations that invoke effector cells such as innate lymphoid cells may provide an environment that promote effector mechanisms including T cell and B cell mediated immunity. Identifying pathways associated with killing this highly successful infectious agent has become critical to achieving the goal of reducing the global tuberculosis burden.
journal_name
Curr Opin Immunoljournal_title
Current opinion in immunologyauthors
Izzo AAdoi
10.1016/j.coi.2017.07.008subject
Has Abstractpub_date
2017-08-01 00:00:00pages
78-84eissn
0952-7915issn
1879-0372pii
S0952-7915(16)30099-1journal_volume
47pub_type
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journal_title:Current opinion in immunology
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journal_title:Current opinion in immunology
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journal_title:Current opinion in immunology
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journal_title:Current opinion in immunology
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journal_title:Current opinion in immunology
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