Abstract：
:Pulse oximetry, a noninvasive technique of measuring oxygen saturation continuously, is being used increasingly in the intensive care setting. This article provides information regarding physiologic basis and practical aspects of clinical usage of pulse oximetry in the neonate, both in medical and surgical units.
journal_name
Clin Perinatoljournal_title
Clinics in perinatologyauthors
Dziedzic K,Vidyasagar Dsubject
Has Abstractpub_date
1989-03-01 00:00:00pages
177-97issue
1eissn
0095-5108issn
1557-9840journal_volume
16pub_type
杂志文章,评审abstract：:For more than 100 years, three principles have guided the treatment of neonatal asphyxia: maintain body heat, free air passages of obstructions, and stimulate respiration by supplying air to the lungs for oxygenation of the blood. This article addresses the question of which gas, air or 100% oxygen, is best supplied t...
journal_title：Clinics in perinatology
pub_type： 杂志文章,评审
doi：10.1016/j.clp.2005.11.003
更新日期：2006-03-01 00:00:00
abstract：:This article explains the mechanisms underlying choices of pharmacotherapy for hypoxic-ischemic insults of both preterm and term babies. Some preclinical data are strong enough that clinical trials are now underway. Challenges remain in deciding the best combination therapies for each age and insult. ...
journal_title：Clinics in perinatology
pub_type： 杂志文章,评审
doi：10.1016/j.clp.2013.09.004
更新日期：2014-03-01 00:00:00
abstract：:Prematurity is the leading cause of perinatal morbidity and mortality in the industrial world, occurring in 4% to 9% of all deliveries, a rate that has remained unchanged during the past decades. Despite the relative minority of obstetric patients affected by this problem, prematurity is responsible for approximately ...
journal_title：Clinics in perinatology
pub_type： 杂志文章,评审
doi：
更新日期：1998-09-01 00:00:00
abstract：:Neonatology has optimized medical outcomes for high-risk newborns yet neurodevelopmental outcomes continue to be a concern. Basic science, clinical research, and environmental design perspectives have shown the impact of the caregiving environment on the developing brain and the role of professional caregivers in prov...
journal_title：Clinics in perinatology
pub_type： 杂志文章,评审
doi：10.1016/j.clp.2011.08.003
更新日期：2011-12-01 00:00:00
abstract：:Ischemic perinatal stroke (IPS) occurs in 1 of 2300 to 5000 live births. It is an under-recognized cause of significant long-term disabilities, including hemiplegic cerebral palsy, epilepsy, cognitive delays, and behavioral impairments. The pathophysiology is complex and multifactorial, involving maternal, fetal, plac...
journal_title：Clinics in perinatology
pub_type： 杂志文章
doi：10.1016/j.clp.2008.09.008
更新日期：2009-03-01 00:00:00
abstract：:Late preterm neonates have unique susceptibilities to infection. The closed setting of the neonatal ICU (NICU) and the immunologic immaturity of premature infants set the state for the development of nosocomial infections. This article discusses infections that might be seen in this population and gives options for di...
journal_title：Clinics in perinatology
pub_type： 杂志文章,评审
doi：10.1016/j.clp.2006.09.005
更新日期：2006-12-01 00:00:00
abstract：:The extensive data from animal models of BPD and specific aspects of lung injury have helped to expand and refine the concept of pathogenesis introduced by Northway et al. Given the complexity and heterogeneity of the human illness, it is unreasonable to presume that any single model or research group could elucidate ...
journal_title：Clinics in perinatology
pub_type： 杂志文章,评审
doi：
更新日期：1992-09-01 00:00:00
abstract：:Congenital lobar emphysema is an uncommon but potentially life-threatening cause of respiratory distress in the newborn. The clinical picture and radiologic findings are diagnostic. Lobectomy in the distressed neonate is curative. In infants with onset of symptoms between one and four months of age surgery may not be ...
journal_title：Clinics in perinatology
pub_type： 杂志文章
doi：
更新日期：1978-03-01 00:00:00
abstract：:Despite the fact that hypoglycemia is an extremely common disorder of the newborn, consensus has been difficult to reach regarding definition, diagnosis, outcome, and treatment. With improved neuroradiologic techniques, such as MRI and PET scanning becoming increasingly available, studies to determine the correlation ...
journal_title：Clinics in perinatology
pub_type： 杂志文章,评审
doi：10.1016/s0095-5108(02)00054-4
更新日期：2002-12-01 00:00:00
abstract：:Correct fluid and electrolyte concentrations are essential to reduce mortality in critically ill infants. The authors list considerations in calculating the necessary maintenance volumes and emphasize the importance of continuous monitoring of data and a review and retabulation every eight hours, because requirements ...
journal_title：Clinics in perinatology
pub_type： 杂志文章,评审
doi：
更新日期：1979-03-01 00:00:00
abstract：:Cardiovascular malformations (CVMs) are the most common birth defect, occurring in 1% to 5% of all live births. Genetic, epigenetic, and environmental factors all influence the development of CVMs, and an improved understanding of the causation of CVMs is a prerequisite for prevention. Cardiac development is a complex...
journal_title：Clinics in perinatology
pub_type： 杂志文章,评审
doi：10.1016/j.clp.2015.11.002
更新日期：2016-03-01 00:00:00
abstract：:HFV is a mode of therapy that allows gas exchange with pressure fluctuations much lower than that required for conventional ventilation, and may consequently decrease the incidence of barotrauma and chronic lung disease. At present the National Institute of Health is sponsoring the first large controlled trial to test...
journal_title：Clinics in perinatology
pub_type： 杂志文章,评审
doi：
更新日期：1987-09-01 00:00:00
abstract：:We emphasize again that the prevalence of maternal infections may vary in different populations, and others might arrive at different estimates about the percentage of infants colonized and, concerning those infants colonized, about the percentage with adverse outcomes. Additionally, many women are colonized or infect...
journal_title：Clinics in perinatology
pub_type： 杂志文章,评审
doi：
更新日期：1997-03-01 00:00:00
abstract：:Cesarean delivery as a result of maternal request is increasingly popular, leading to important ethical questions. One of the challenging issues is balancing respect for the autonomy of a pregnant woman with concerns of beneficence and nonmaleficence for her and the fetus. The perceived benefit of cesarean section is ...
journal_title：Clinics in perinatology
pub_type： 杂志文章,评审
doi：10.1016/j.clp.2008.03.011
更新日期：2008-06-01 00:00:00
abstract：:Cytomegalovirus (CMV) is reactivated in the lactating breast in up to 96% of CMV seropositive mothers. There is a relevant entity of postnatally acquired symptomatic CMV infection and disease of preterm infants through raw breast milk (BM). Actual data support negative influence on long-term cognitive development. Con...
journal_title：Clinics in perinatology
pub_type： 杂志文章,评审
doi：10.1016/j.clp.2016.11.012
更新日期：2017-03-01 00:00:00
abstract：:The enunciation of equipment requirements has been attempted as needs appear today. Detailed and technical specifications for some of this equipment must be understood prior to major acquisitions. An awareness of current trends in clinical research can often be obtained from appropriate consultants which should forest...
journal_title：Clinics in perinatology
pub_type： 杂志文章
doi：
更新日期：1976-09-01 00:00:00
abstract：:Several microangiopathic disorders that are encountered during pregnancy provide physicians with a formidable diagnostic challenge. Severe pre-eclampsia with hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome and many other obstetric and medical or surgical conditions produce similar clinical presen...
journal_title：Clinics in perinatology
pub_type： 杂志文章,评审
doi：10.1016/j.clp.2004.06.007
更新日期：2004-12-01 00:00:00
abstract：:Decision-making for extremely immature preterm infants at the margins of viability is ethically, professionally, and emotionally complicated. A standard for prenatal consultation should be developed incorporating assessment of parental decision-making preferences and styles, a communication process involving a recipro...
journal_title：Clinics in perinatology
pub_type： 杂志文章
doi：10.1016/j.clp.2011.06.004
更新日期：2011-09-01 00:00:00
abstract：:Nonstress testing appears to be an effective means of identifying fetal condition. Its most definitive benefit is the identification of the "normal" fetus, which often permits a path of nonintervention. A significant benefit of the nonstress test approach is its simplicity and portability which, in a practical sense, ...
journal_title：Clinics in perinatology
pub_type： 杂志文章,评审
doi：
更新日期：1982-06-01 00:00:00
abstract：:Although therapies in addition to whole-body cooling are being developed to treat the neonate at risk for hypoxic-ischemic encephalopathy, we have no quickly measured serum inflammatory or neuronal biomarkers to acutely and accurately identify brain injury or to follow the efficacy of therapy. This review covers infla...
journal_title：Clinics in perinatology
pub_type： 杂志文章,评审
doi：10.1016/j.clp.2016.04.008
更新日期：2016-09-01 00:00:00
abstract：:Beta-sympathomimetic agents are used extensively in obstetrics to inhibit premature labor. Knowledge of the pharmacology, mode of action on smooth muscle, and cardiovascular and metabolic side effects of these agents is essential for the obstetrician and perinatologist. This review article draws extensively on recent ...
journal_title：Clinics in perinatology
pub_type： 杂志文章,评审
doi：
更新日期：1987-12-01 00:00:00
abstract：:Retinopathy of Prematurity (ROP) is a leading cause of childhood blindness in the United States. Optical Coherence Tomography (OCT) is a relatively new imaging technology capable of imaging ocular structures in cross section at high resolution. We present an age-customized approach to perform Spectral Domain OCT in ne...
journal_title：Clinics in perinatology
pub_type： 杂志文章,评审
doi：10.1016/j.clp.2013.02.007
更新日期：2013-06-01 00:00:00
abstract：:Diabetic pregnancies involve complex alterations in maternal-placental and fetal compartments. This article discusses the unique features of diabetic pregnancies as they pertain to the maternal changes that must occur to accommodate the fetus. ...
journal_title：Clinics in perinatology
pub_type： 杂志文章,评审
doi：
更新日期：1983-10-01 00:00:00
abstract：:Outcomes of neonatal intensive care unit (NICU) graduates have been categorized by rates of neurodevelopmental impairment at 2 years old. Although useful as metrics for research, these early childhood assessments may underestimate or overestimate later functional capabilities. Often overlooked are less severe but more...
journal_title：Clinics in perinatology
pub_type： 杂志文章,评审
doi：10.1016/j.clp.2018.05.008
更新日期：2018-09-01 00:00:00
abstract：:This article summarizes the commonly used biomarkers currently available for diagnosis of necrotizing enterocolitis. The most exciting advances in diagnostic tests were the use of new nucleic acid sequencing techniques (eg, next-generation sequencing) and molecular screening methods (eg, proteomics and microarray anal...
journal_title：Clinics in perinatology
pub_type： 杂志文章,评审
doi：10.1016/j.clp.2012.12.005
更新日期：2013-03-01 00:00:00
abstract：:There are various causes for frequent desaturations in infants. Frequent hypoxemia is a significant change in clinical status and must be investigated carefully for possible etiology. When common extra-airway causes for desaturation are ruled out, one should attempt to distinguish between central apnea and obstructive...
journal_title：Clinics in perinatology
pub_type： 历史文章,杂志文章,评审
doi：10.1016/j.clp.2006.12.013
更新日期：2007-03-01 00:00:00
abstract：:Although hyperbilirubinemia is extremely common among neonates and is usually mild and transient, it sometimes leads to bilirubin-induced neurologic damage (BIND). The auditory pathway is highly sensitive to the effects of elevated total serum/plasma bilirubin (TB) levels, with damage manifesting clinically as auditor...
journal_title：Clinics in perinatology
pub_type： 杂志文章,评审
doi：10.1016/j.clp.2016.01.006
更新日期：2016-06-01 00:00:00
abstract：:Cesarean deliveries can be associated with moderate to severe postoperative pain. Appropriate management of pain is important because it results in better patient satisfaction, earlier mobilization, and improved maternal-infant bonding. There are many individual options for treatment of pain; however, multimodal analg...
journal_title：Clinics in perinatology
pub_type： 杂志文章,评审
doi：10.1016/j.clp.2013.05.008
更新日期：2013-09-01 00:00:00
abstract：:The past 15 years has seen the resurgence of an interest in biomedical ethics and an awareness of the importance of teaching this discipline in medical curricula at varying levels. Physicians and philosophers can work together to achieve an integration of clinical case material and philosophical theory, in order to te...
journal_title：Clinics in perinatology
pub_type： 杂志文章
doi：
更新日期：1987-06-01 00:00:00
abstract：:Congenital heart defects (CHDs) are structural abnormalities of the heart and great vessels that are present from birth. The presence or absence of extracardiac anomalies has historically been used to identify patients with possible monogenic, chromosomal, or teratogenic CHD causes. These distinctions remain clinicall...
journal_title：Clinics in perinatology
pub_type： 杂志文章,评审
doi：10.1016/j.clp.2015.02.009
更新日期：2015-06-01 00:00:00
