Abstract:
:Cesarean delivery as a result of maternal request is increasingly popular, leading to important ethical questions. One of the challenging issues is balancing respect for the autonomy of a pregnant woman with concerns of beneficence and nonmaleficence for her and the fetus. The perceived benefit of cesarean section is protection of the pelvic floor. Increased rates of respiratory morbidity in infants born by cesarean section cannot be ignored. Societal concerns of distribution of resources must be considered in ongoing discussions of this critical issue. This article reviews the current ethical debate of maternal choice and autonomy in elective cesarean delivery.
journal_name
Clin Perinatoljournal_title
Clinics in perinatologyauthors
Williams HOdoi
10.1016/j.clp.2008.03.011subject
Has Abstractpub_date
2008-06-01 00:00:00pages
455-62, viiiissue
2eissn
0095-5108issn
1557-9840pii
S0095-5108(08)00026-2journal_volume
35pub_type
杂志文章,评审abstract::Stem cell transplantation (SCT) is an established first-line or adjunctive therapy for a variety of neonatal and adult diseases. New evidence in preclinical models as well as a few human studies show the potential utility of SCT in neuroprotection and in the modulation of inflammatory injury in at risk-neonates. This ...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2015.04.008
更新日期:2015-09-01 00:00:00
abstract::Visual evoked potentials (VEPs) are easily recorded in the neonatal intensive care setting using light-emitting diode goggles as the flash stimulus. They are sensitive measures of CNS integrity and are altered or abolished by hypoxia. Prognosis in newborns with birth asphyxia or hypoxia is difficult to predict; howeve...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1993-06-01 00:00:00
abstract::Medical liability coverage has become increasingly expensive and scarce since 2001, especially for obstetrics and other high-risk specialties. Physicians, whose own fees are constrained, see this as a crisis needing tort reform to cap payouts. Plaintiffs' lawyers fight caps; they blame insurance trends and call for st...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2004.11.003
更新日期:2005-03-01 00:00:00
abstract::This article discusses the management of short bowel syndrome during the neonatal period. It includes information regarding etiology and pathophysiology and parenteral and enteral nutrition therapy. Finally, a discussion of the role of intestinal transplantation in the treatment of short bowel syndrome is included. ...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1996-06-01 00:00:00
abstract::Discussed in this article are the effects of pregnancy-induced hypertension on the renin-angiotensin-aldosterone system; the possible role of prostanoids, deoxycorticosterone, and deoxycorticosterone sulfate in blood pressure control; and the effect of pregnancy-induced hypertension upon the endocrinology of the mater...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1983-10-01 00:00:00
abstract::New knowledge has accumulated in recent years making it prudent to ask questions regarding current oxygenation policies and guidelines. Because new-born resuscitation affects so many individuals, and because resuscitation procedures may have dramatic consequences on infant and child health, intensified discussion and ...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2004.04.021
更新日期:2004-09-01 00:00:00
abstract::Many aspects of the forward propulsion of enteral nutrients are not fully mature in the preterm and term neonate. Because the regulation of motor activity in the gastrointestinal tract is complex and multifaceted, many levels of regulation of this activity are immature in the preterm infant; however, as neonatologists...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1996-06-01 00:00:00
abstract::Neutropenia, a below normal concentration of neutrophils in the circulating blood, can be the kinetic result of diminished neutrophil production, excessive neutrophil margination, or accelerated neutrophil utilization and destruction. The significance of neutropenia to the well-being of the subject is dependent, in pa...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1995-09-01 00:00:00
abstract::Postpartum hemorrhage is an obstetric emergency that represents a major cause of maternal morbidity and mortality. With the recent rise in the cesarean delivery rate, prompt recognition and proper management at the time of cesarean delivery are becoming increasingly important for providers of obstetrics. Preparedness ...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2008.07.007
更新日期:2008-09-01 00:00:00
abstract::Fetal and neonatal infections can occur at different times during pregnancy, from conception to birth. Infections that take place near the time of conception often destroy the zygote or embryo and only rarely leave definitive evidence. The mother can transmit the infection to her fetus through several routes, but the ...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1988-06-01 00:00:00
abstract::The extensive data from animal models of BPD and specific aspects of lung injury have helped to expand and refine the concept of pathogenesis introduced by Northway et al. Given the complexity and heterogeneity of the human illness, it is unreasonable to presume that any single model or research group could elucidate ...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1992-09-01 00:00:00
abstract::Familial hypothyroidism results from both thyroidal and extrathyroidal dysfunction. Specific intrathyroidal abnormalities in thyroid hormone synthesis causing goitrous hypothyroidism are iodide trap defect, organification defect, "coupling" defect, iodoprotein defect, and dehalogenase defect. The diagnostic studies fo...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1976-03-01 00:00:00
abstract::Administrative data research on maternal racial disparities supports 2 broad clinical inferences. First, failure to rescue in terms of both death and severe maternal morbidity likely accounts for a significant proportion of maternal disparities. Second, risk for adverse outcomes by race is generally differential with ...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2020.08.008
更新日期:2020-12-01 00:00:00
abstract::Dysphagia and aspiration are commonly encountered problems in the neonatal population. It is often multifactorial in nature and management should be tailored to the individual patient. Multiple causes should be considered, including anatomic abnormalities, neurologic/developmental delay, cardiopulmonary disease/infect...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2018.07.005
更新日期:2018-12-01 00:00:00
abstract::Continuous positive airway pressure (CPAP) systems can be broadly grouped into continuous flow or variable flow devices. Bubble CPAP (bCPAP) is a continuous flow device and has physiologic properties that could facilitate gas exchange. Its efficacy has been reported to be similar to variable flow CPAP systems when use...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2016.07.003
更新日期:2016-12-01 00:00:00
abstract::We emphasize again that the prevalence of maternal infections may vary in different populations, and others might arrive at different estimates about the percentage of infants colonized and, concerning those infants colonized, about the percentage with adverse outcomes. Additionally, many women are colonized or infect...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1997-03-01 00:00:00
abstract::Antepartum fetal surveillance with Doppler ultrasound of umbilical artery has shown significant diagnostic efficacy in identifying fetal compromise in pregnancies complicated with fetal growth restriction (FGR). Its effectiveness in decreasing perinatal mortality has been shown by randomized clinical trials (Level I e...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2010.12.004
更新日期:2011-03-01 00:00:00
abstract::Although it has been customary to treat neonatal jaundice at lower serum bilirubin levels in low-birth weight infants than in term infants, the threshold bilirubin levels and long-term benefits for early treatment of preterm infants have not been validated. This article summarizes and evaluates existing evidence and s...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/s0095-5108(05)70012-9
更新日期:2000-03-01 00:00:00
abstract::For adults and pediatric age patients, high-dose intravenous epinephrine was recommended if standard-dose epinephrine failed to achieve return of spontaneous circulation. More recent trials suggest that high-dose epinephrine is not beneficial and may result in increased harm. There are no randomized clinical studies o...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2005.11.016
更新日期:2006-03-01 00:00:00
abstract::Hemoglobinopathies are frequently occurring disorders for which prenatal diagnosis is possible. Couples in which one parent has microcytic hypochromic red blood cells; is of Southeast Asian, Mediterranean, Middle Eastern, Indian, or African origin; or had one previous child with a known hemoglobinopathy or a previous ...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1990-12-01 00:00:00
abstract::This article summarizes the commonly used biomarkers currently available for diagnosis of necrotizing enterocolitis. The most exciting advances in diagnostic tests were the use of new nucleic acid sequencing techniques (eg, next-generation sequencing) and molecular screening methods (eg, proteomics and microarray anal...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2012.12.005
更新日期:2013-03-01 00:00:00
abstract::Pulmonary hypertension in the perinatal period can present acutely (persistent pulmonary hypertension of the newborn) or chronically. Clinical and echocardiographic diagnosis of acute pulmonary hypertension is well accepted but there are no broadly validated criteria for echocardiographic diagnosis of pulmonary hypert...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2015.11.013
更新日期:2016-03-01 00:00:00
abstract::Pulse oximetry, a noninvasive technique of measuring oxygen saturation continuously, is being used increasingly in the intensive care setting. This article provides information regarding physiologic basis and practical aspects of clinical usage of pulse oximetry in the neonate, both in medical and surgical units. ...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1989-03-01 00:00:00
abstract::Human milk provided by healthy and well-nourished mothers is believed to cover the infant's nutrient requirements during the first half year of life. It is composed of a mixture of nutritive components as well as other bioactive factors with relevant physiologic effects in the neonate infant. Human milk composition ha...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1999-06-01 00:00:00
abstract::Moderate preterm, late preterm, and early term deliveries represent a major and growing public health concern. These deliveries are associated with significant financial burden and pose serious risks to mothers and newborns. Women who deliver at moderate and late gestational ages in one pregnancy are at increased risk...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2013.07.001
更新日期:2013-12-01 00:00:00
abstract::A regionalized system of perinatal care, which draws on the strengths of individual hospitals and corrects any weaknesses, can enhance the level of performance of the community hospital. Although the care of high risk infants takes priority in this system, concern is expressed that routine perinatal care should also r...
journal_title:Clinics in perinatology
pub_type: 杂志文章
doi:
更新日期:1980-03-01 00:00:00
abstract::The photoplethysmogram (PPG) is a noninvasive circulatory signal related to the pulsatile volume in tissue and is displayed by many pulse oximeters. The PPG is similar in appearance to the invasive arterial waveform, but is noninvasive and ubiquitous in hospitals. There is increasing interest in seeking circulatory in...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2012.06.012
更新日期:2012-09-01 00:00:00
abstract::Congenital diaphragmatic hernia (CDH) is a common birth anomaly. Absence or presence of liver herniation and determination of lung-to-head ratio are the most accurate predictors of prognosis for fetuses with CDH. Though open fetal CDH repair has been abandoned, fetal endoscopic balloon tracheal occlusion promotes lung...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2012.04.005
更新日期:2012-06-01 00:00:00
abstract::Preterm birth remains a significant health concern. Maternal reproductive infections such as bacterial vaginosis pose increased risk for preterm birth, although treatment of bacterial vaginosis has not proven to be universally effective in preterm birth prevention. Maternal oral infection such as clinical periodontal ...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2005.05.002
更新日期:2005-09-01 00:00:00
abstract::The fetal environment is thus well suited for normal growth and development with oxygen availability exceeding oxidative needs. With impairments in blood gas exchange this excess oxygen acts as a "margin of safety," providing for the maintenance of oxidative metabolism through increases in fractional O2 extraction, al...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1989-09-01 00:00:00