Inflammatory Biomarkers of Birth Asphyxia.

abstract：:It is estimated that 4 million children die each year of vaccine-preventable diseases and another 4 million are permanently disabled. Although vaccination is the most cost-effective health method, there is a discrepancy between our level of knowledge and practices applied. Vaccination of pregnant women provides the mo...

journal_title：Clinics in perinatology

authors： Linder N,Ohel G

更新日期：1994-09-01 00:00:00

abstract：:The photoplethysmogram (PPG) is a noninvasive circulatory signal related to the pulsatile volume in tissue and is displayed by many pulse oximeters. The PPG is similar in appearance to the invasive arterial waveform, but is noninvasive and ubiquitous in hospitals. There is increasing interest in seeking circulatory in...

journal_title：Clinics in perinatology

authors： Sahni R

更新日期：2012-09-01 00:00:00

abstract：:Antimicrobial-resistant pathogens are of increasing concern in the neonatal intensive care unit population. A myriad of resistance mechanisms exist in microorganisms, and management can be complex because broad-spectrum antibiotics are increasingly needed. Control and prevention of antibiotic-resistant organisms (AROs...

journal_title：Clinics in perinatology

authors： Patel SJ,Saiman L

更新日期：2010-09-01 00:00:00

abstract：:The risk of mother-to-child transmission (MTCT) of HIV can be reduced through cesarean delivery prior to the onset of labor and prior to rupture of the membranes (elective cesarean delivery [ECD]). As a result of this evidence, the American College of Obstetricians and Gynecologists and the Department of Health and Hu...

journal_title：Clinics in perinatology

authors： Legardy-Williams JK,Jamieson DJ,Read JS

更新日期：2010-12-01 00:00:00

abstract：:Neonatal sepsis continues to take a devastating toll globally. Although adequate to protect against invasive infection in most newborns, the distinct function of neonatal innate host defense coupled with impairments in adaptive immune responses increases the likelihood of acquiring infection early in life, with subseq...

journal_title：Clinics in perinatology

authors： Wynn JL,Levy O

更新日期：2010-06-01 00:00:00

abstract：:It is clear that prostaglandins and related compounds are important in the physiology and pathophysiology of the perinatal pulmonary circulation. This article focuses on what is known about prostaglandin-related compounds (PRC) in the pulmonary circulation of the developing and newly born mammal. Also included is a di...

journal_title：Clinics in perinatology

authors： Philips JB 3rd,Lyrene RK

更新日期：1984-10-01 00:00:00

abstract：:New knowledge has accumulated in recent years making it prudent to ask questions regarding current oxygenation policies and guidelines. Because new-born resuscitation affects so many individuals, and because resuscitation procedures may have dramatic consequences on infant and child health, intensified discussion and ...

journal_title：Clinics in perinatology

authors： Saugstad OD

更新日期：2004-09-01 00:00:00

abstract：:To understand medical disorders such as obstructive apnea, or pulmonary aspiration, one must understand the many functions performed by the upper airway. These functions include respiration, airway protection at the face, feeding, and regulation of thoracoabdominal pressure. The neuromuscular mechanisms that perform t...

journal_title：Clinics in perinatology

authors： Thach BT

更新日期：1992-12-01 00:00:00

abstract：:Congenital diaphragmatic hernia (CDH) is a common birth anomaly. Absence or presence of liver herniation and determination of lung-to-head ratio are the most accurate predictors of prognosis for fetuses with CDH. Though open fetal CDH repair has been abandoned, fetal endoscopic balloon tracheal occlusion promotes lung...

journal_title：Clinics in perinatology

authors： Shue EH,Miniati D,Lee H

更新日期：2012-06-01 00:00:00

abstract：:A number of ethical considerations arise with regard to screening for, detecting, and managing fetal anomalies. Some of these considerations involve the need to give attention to emotional distress the pregnant woman might be experiencing. The ethical principle of beneficence gives rise to a duty of the obstetrician t...

journal_title：Clinics in perinatology

authors： Strong C

更新日期：2003-03-01 00:00:00

abstract：:Beta-sympathomimetic agents are used extensively in obstetrics to inhibit premature labor. Knowledge of the pharmacology, mode of action on smooth muscle, and cardiovascular and metabolic side effects of these agents is essential for the obstetrician and perinatologist. This review article draws extensively on recent ...

journal_title：Clinics in perinatology

authors： Nuwayhid B,Rajabi M

更新日期：1987-12-01 00:00:00

abstract：:Pharmacotherapy for gastroesophageal reflux (GER) in neonates, aimed at interfering with this physiologic process and potentially reducing the negative sequelae that providers often attribute to GER, consists primarily of drugs that increase the viscosity of feeds, reduce stomach acidity, or improve gut motility. Medi...

journal_title：Clinics in perinatology

authors： Malcolm WF,Cotten CM

更新日期：2012-03-01 00:00:00

abstract：:The epitome of FAS and ARBD has been documented substantially in the medical literature. There appears to be little question that alcohol is a teratogen. The precise nature for the mechanism of causing congenital defects, whether it be direct or indirect, is still unknown. There is no unequivocal information that can ...

journal_title：Clinics in perinatology

authors： Pietrantoni M,Knuppel RA

更新日期：1991-03-01 00:00:00

abstract：:The incidence of neonatal abstinence syndrome owing to prenatal opioid exposure has grown rapidly in recent decades and it disproportionately affects rural, non-white, and public insurance-dependent populations. Treatment consists of pharmacologic and nonpharmacologic interventions with wide variability in approaches ...

journal_title：Clinics in perinatology

authors： MacMillan KDL

更新日期：2019-12-01 00:00:00

abstract：:Visual evoked potentials (VEPs) are easily recorded in the neonatal intensive care setting using light-emitting diode goggles as the flash stimulus. They are sensitive measures of CNS integrity and are altered or abolished by hypoxia. Prognosis in newborns with birth asphyxia or hypoxia is difficult to predict; howeve...

journal_title：Clinics in perinatology

authors： Whyte HE

更新日期：1993-06-01 00:00:00

abstract：:Postpartum hemorrhage is an obstetric emergency that represents a major cause of maternal morbidity and mortality. With the recent rise in the cesarean delivery rate, prompt recognition and proper management at the time of cesarean delivery are becoming increasingly important for providers of obstetrics. Preparedness ...

journal_title：Clinics in perinatology

authors： Bonanno C,Gaddipati S

更新日期：2008-09-01 00:00:00

abstract：:Nonstress testing appears to be an effective means of identifying fetal condition. Its most definitive benefit is the identification of the "normal" fetus, which often permits a path of nonintervention. A significant benefit of the nonstress test approach is its simplicity and portability which, in a practical sense, ...

journal_title：Clinics in perinatology

authors： Paul RH

更新日期：1982-06-01 00:00:00

abstract：:Congenital heart defects (CHDs) are structural abnormalities of the heart and great vessels that are present from birth. The presence or absence of extracardiac anomalies has historically been used to identify patients with possible monogenic, chromosomal, or teratogenic CHD causes. These distinctions remain clinicall...

journal_title：Clinics in perinatology

authors： Cowan JR,Ware SM

更新日期：2015-06-01 00:00:00

abstract：:It is now recognized that pregnancy is associated with significant changes in maternal thyroid function that are largely mediated by the placenta. The author summarizes the understanding of these changes during pregnancy and follows with a discussion of fetal thyroid system ontogenesis. ...

journal_title：Clinics in perinatology

authors： Fisher DA

更新日期：1983-10-01 00:00:00

abstract：:Preterm births remain a major cause of neonatal morbidity and mortality despite our efforts over the past several decades. Our improved understanding of the complex mechanisms surrounding preterm labor, however, has resulted in the development of numerous biologic and clinical predictors of spontaneous preterm births....

journal_title：Clinics in perinatology

authors： Lu GC,Goldenberg RL

更新日期：2000-06-01 00:00:00

abstract：:The Healthy People 2000 objectives for breastfeeding were to move the breastfeeding initiation rate to 75% from 54% and the breastfeeding continuation rate to 50% at age 6 months from the 1988 baseline of 21%. The 1996 data indicated that the goal will not be met either for initiation or duration in spite of governmen...

journal_title：Clinics in perinatology

authors： Cadwell K

更新日期：1999-06-01 00:00:00

abstract：:Cytomegalovirus (CMV) is reactivated in the lactating breast in up to 96% of CMV seropositive mothers. There is a relevant entity of postnatally acquired symptomatic CMV infection and disease of preterm infants through raw breast milk (BM). Actual data support negative influence on long-term cognitive development. Con...

journal_title：Clinics in perinatology

authors： Hamprecht K,Goelz R

更新日期：2017-03-01 00:00:00

abstract：:The care of extremely premature infants involves a number of complex clinical and ethical issues. The ethical and scientific quality of decisions made in the care of these infants has profound long-term consequences for these infants and their families. In circumstances when it is unclear whether intensive care should...

journal_title：Clinics in perinatology

authors： Tyson JE,Stoll BJ

更新日期：2003-06-01 00:00:00

abstract：:Extracorporeal membrane oxygenation (ECMO) has gained notoriety recently as a treatment of last resort for neonates at term or near term who suffer from pulmonary failure. Because of serious inherent risks, the procedure is at present reserved for infants with reversible pulmonary disease who have failed conventional ...

journal_title：Clinics in perinatology

authors： Stork E

更新日期：1988-12-01 00:00:00

abstract：:Complex biochemical consequences are the result of a series of secondary biochemical changes caused by oxygen depletion. Hypoxia in the fetus and neonate results in decreased GI blood flow, especially to the GI mucosa. Although severe O2 deprivation cannot be entirely compensated for, an increase in tissue O2 extracti...

journal_title：Clinics in perinatology

authors： Goplerud JM,Delivoria-Papadopoulos M

更新日期：1986-03-01 00:00:00

abstract：:Preterm birth is a major complication of pregnancy and remains a leading cause of neonatal morbidity and mortality worldwide. Improvements in the authors' understanding of the pathophysiology of preterm labor have led to the development of novel diagnostic tools of use to identify women at greatest risk for preterm bi...

journal_title：Clinics in perinatology

authors： Ramsey PS,Andrews WW

更新日期：2003-12-01 00:00:00

abstract：:When cystic hygroma is detected antenatally, the prognosis is usually poor, and intrauterine or neonatal death are common. This seems especially true for Turner syndrome (the largest etiologic group associated with cystic hygroma) and the lethal multiple pterygium syndromes. However, some fetuses with Turner syndrome,...

journal_title：Clinics in perinatology

authors： Edwards MJ,Graham JM Jr

更新日期：1990-09-01 00:00:00

abstract：:Pulmonary hypertension in the newborn infant has many potential causes, and multiple etiologies are common. In this article, the author outlines the basic principles in pathophysiology, classification, and etiology that should be well understood by those who care for neonates with disease processes in which pulmonary ...

journal_title：Clinics in perinatology

authors： Gersony WM

更新日期：1984-10-01 00:00:00

abstract：:Exogenous surfactant therapy has been a significant advance in the management of preterm infants with RDS. It has become established as a standard part of the management of such infants. Both natural and synthetic surfactants lead to clinical improvement and decreased mortality, with natural surfactants having additio...

journal_title：Clinics in perinatology

authors： Suresh GK,Soll RF

更新日期：2001-09-01 00:00:00

abstract：:Fetal and neonatal infections can occur at different times during pregnancy, from conception to birth. Infections that take place near the time of conception often destroy the zygote or embryo and only rarely leave definitive evidence. The mother can transmit the infection to her fetus through several routes, but the ...

journal_title：Clinics in perinatology

authors： Zeichner SL,Plotkin SA

更新日期：1988-06-01 00:00:00