Assessment of Optic Nerve Head Pallor in Primary Open-Angle Glaucoma Patients and Healthy Subjects.

abstract：PURPOSE:To examine the morphological changes in the meibomian glands of eyes of patients with dry eye disease using the non-contact infrared meibography system and to assess their relationship with meibomian dropout, signs, and tear-film function. METHODS:Subjects included 264 randomly selected patients (528 eyes) suf...

journal_title：Current eye research

authors： Feng Y,Gao Z,Feng K,Qu H,Hong J

更新日期：2014-10-01 00:00:00

abstract：:The short and long term response of the trabecular meshwork to a phagocytic challenge and the response of the meshwork to different types of foreign particles was studied by injecting one eye of 25 adult cats with a phagocytic agent (zymosan, blood, or latex microspheres) while the fellow eye received a control soluti...

journal_title：Current eye research

authors： Johnson DH,Richardson TM,Epstein DL

更新日期：1989-11-01 00:00:00

abstract：PURPOSE:To evaluate indocyanine green angiography (ICGA) for the identification and characterization of afferent (feeding) and efferent (draining) vessels in patients with ocular surface neoplasia. MATERIALS AND METHODS:Consecutive patients with biopsy-proven benign, pre-invasive, or invasive ocular surface tumors of ...

journal_title：Current eye research

authors： Brunner M,Steger B,Romano V,Hodson M,Zheng Y,Heimann H,Kaye SB

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:To compare the quality of corneal endothelium of precut Descemet-stripping automated endothelial keratoplasty (DSAEK) tissue when transported with and without the anterior lamellar corneal tissue (ALCT) when organ-culture corneal storage methods are used. METHODS:After microkeratome-assisted excision of anteri...

journal_title：Current eye research

authors： Jhanji V,Pollock GA,Mackey AL,Beltz J,Vajpayee RB

更新日期：2012-02-01 00:00:00

abstract：:Goggles that degrade the retinal image produce axial enlargement of the ocular globe and large myopic refractive errors. Many authors have assumed that visual image degradation itself leads to myopia. Hodos and co-authors have shown, however, that goggled eyes in chicks are considerably warmer than normal. Such temper...

journal_title：Current eye research

authors： Shih YF,Fitzgerald ME,Norton TT,Gamlin PD,Hodos W,Reiner A

更新日期：1993-03-01 00:00:00

abstract：PURPOSE:The effects of several serotonergic agonists on aqueous humor formation (AHF), total outflow facility (OF) and intraocular pressure (IOP) were investigated in living cynomolgus monkeys. METHODS:We determined the effect of a single topical unilateral 300 microg or 3 mg dose of the 5-HT agonists serotonin, 5-car...

journal_title：Current eye research

authors： Gabelt BT,Millar CJ,Kiland JA,Peterson JA,Seeman JL,Kaufman PL

更新日期：2001-08-01 00:00:00

abstract：PURPOSE:To measure the cell size and cell density in five layers of the central cornea in the widely used inbred C57BL/6 mouse strain using in vivo three-dimensional (3D) two-photon (2PH) imaging. METHODS:Corneas were scanned using a 2PH laser scanning fluorescence microscope after staining with plasma membrane stain ...

journal_title：Current eye research

authors： Zhang H,He S,Liu S,Xie Y,Chen G,Zhang J,Sun S,Liang D,Wang L

更新日期：2016-04-01 00:00:00

abstract：PURPOSE:This study was undertaken in order to investigate whether the production of vasodilatory prostaglandins is increased in the retinal vasculature of the diabetic rat. METHODS:Diabetes was induced in male Sprague-Dawley rats using streptozotocin. Diabetic rats were left uncontrolled for 3-4 weeks or were treated ...

journal_title：Current eye research

authors： Johnson EI,Dunlop ME,Larkins RG

更新日期：1999-02-01 00:00:00

abstract：:The effects of repeated exposures to UV-A (335 nm) and UV-B (305 nm) radiation on the crystalline lens were studied by treating cultured bovine lenses daily or weekly. The effects of irradiation on lens optical quality were monitored using an automated scanning laser system that records both relative transmittance and...

journal_title：Current eye research

authors： Stuart DD,Cullen AP,Sivak JG,Doughty MJ

更新日期：1994-05-01 00:00:00

abstract：PURPOSE:To evaluate the clinical outcomes of laser in situ keratomileusis (LASIK) using a new approach for the calculation of the ablation profile based on wavefront vertexing from pupil plane to corneal. METHODS:One hundred eyes of 50 patients (age, 21-41 years) with low and moderate myopia were enrolled in this pros...

journal_title：Current eye research

authors： Uceda-Montañés A,Rogers M,Piñero DP

更新日期：2020-09-16 00:00:00

abstract：:In experimental work on retinal ischemia and its medical management, we have been disturbed by the large variations in the electroetinogram (ERG) recovery of rabbit eyes subjected to similar degrees of ischemia. We investigated whether body temperature might be one of the critical factors. We studied pigmented Dutch r...

journal_title：Current eye research

authors： Nayak MS,Marmor MF

更新日期：1995-02-01 00:00:00

abstract：:Free radicals and oxidative damage play roles in aging and age-related ocular diseases such as cataracts, so defensive mechanisms become important factors for protection. Because N-acetylation is involved in a wide variety of detoxification processes, this study was conducted to examine the relationship between the ac...

journal_title：Current eye research

authors： Tamer L,Yilmaz A,Yildirim H,Ayaz L,Ates NA,Karakas S,Oz O,Yildirim O,Atik U

更新日期：2005-10-01 00:00:00

abstract：:Specimens of a cornea, conjunctiva and iris were removed at the time of penetrating keratoplasty in a case of nephropathic cystinosis. Immunohistochemical studies revealed the presence of class II antigens on the stromal keratocytes of the cornea and the vascular endothelial cells, pericytes and fibroblasts of the con...

journal_title：Current eye research

authors： Kaiser-Kupfer MI,Chan CC,Rodrigues M,Datiles MB,Gahl WA

更新日期：1987-04-01 00:00:00

abstract：:The effect of cyclosporine (CsA) treatment in both primary and secondary Chlamydia trachomatis ocular infection in cynomolgus monkeys was studied. Following primary infection, CsA-treated animals developed severe clinical symptoms which persisted for up to 12 weeks compared to control animals which developed less seve...

journal_title：Current eye research

authors： Young E,Schachter J,Prendergast RA,Taylor HR

更新日期：1987-05-01 00:00:00

abstract：PURPOSE:The mechanisms involved in the reported beneficial effects of Calcium dobesilate monohydrate (CaD) for the treatment of diabetic retinopathy (DR) remain to be elucidated. The main aim of the present study is to examine whether CaD prevents early events in the pathogenesis of DR such as neurodegeneration and vas...

journal_title：Current eye research

authors： Solà-Adell C,Bogdanov P,Hernández C,Sampedro J,Valeri M,Garcia-Ramirez M,Pasquali C,Simó R

更新日期：2017-09-01 00:00:00

abstract：:It has been shown that illumination of rod outer segment suspension in the presence of photosensitizers (methylene blue lambda greater than or equal to 620 nm; retinal 370 less than or equal to lambda less than or equal to 390 nm) results in chemical modification of the lipid and protein components of the photo-recept...

journal_title：Current eye research

authors： Shvedova AA,Alekseeva OM,Kuliev IYa,Muranov KO,Kozlov YuP,Kagan VE

更新日期：1982-01-01 00:00:00

abstract：:In the bovine lens the gamma IV-crystallin fraction is a principal determinant of the phase separation and opacification temperature, Tc (Siezen et al, Proc. Natl. Acad. Sci. USA 82, 1985, 1701). We have now measured the effect on Tc of purified gamma IV-crystallin solutions produced by a variety of reagents which aff...

journal_title：Current eye research

authors： Siezen RJ,Benedek GB

更新日期：1985-10-01 00:00:00

abstract：PURPOSE:To demonstrate spectroscopic retinal oximetry measurements on arteries and veins in swine using intravitreal illumination. Retinal arterial and venous saturations are measured for a range of inspired O2 levels after pars plana vitrectomy. METHODS:Pars plana vitrectomy and intravitreal manipulations were perfor...

journal_title：Current eye research

authors： Salyer DA,Beaudry N,Basavanthappa S,Twietmeyer K,Eskandari M,Denninghoff KR,Chipman RA,Park RI

更新日期：2006-07-01 00:00:00

abstract：PURPOSE:To compare the abilities of balanced salt solution, BSS Plus and Hartmann's lactated Ringer's (HLR) solution to maintain the viability of retinal vascular endothelial cells (RVEC) in vitro. METHODS:Cultured retinal vascular endothelial cells were suspended in each irrigating solution for four hours. Viability ...

journal_title：Current eye research

authors： Mourad KM,Edelhauser HF,Capone A Jr,Lynn MJ,Geroski DH

更新日期：1997-03-01 00:00:00

abstract：:Membrane response to the various temperatures as one of the external factors was investigated in the lenses of the poikilothermal animal and the homothermal animal. The rainbow trout lens was used as the poikilothermal material and the rat lens as the homothermal material. The rainbow trout lens maintained in vitro it...

journal_title：Current eye research

authors： Iwata S

更新日期：1985-04-01 00:00:00

abstract：PURPOSE:The aim of this pilot study was to determine the presence of complement activation products in tears from pre- and postkeratoplasty eyes and the fellow eyes in order to investigate the activation of the classical and alternative pathways of the complement system in the early postkeratoplasty period. METHODS:Te...

journal_title：Current eye research

authors： Kerényi A,Nagy G,Veres A,Varga L,Füst A,Nagymihány A,Czumbel N,Süveges I,Füst G

更新日期：2002-02-01 00:00:00

abstract：PURPOSE:To investigate the effect of shaking on corneal endothelial preservation. METHODS:Thirty-six dog corneal buttons were obtained under standard eye bank procedure, after the animals had been sacrificed for cardiovascular experiments in the surgical department. They were equally divided into two groups. In Group ...

journal_title：Current eye research

authors： Wang IJ,Hu FR

更新日期：1997-11-01 00:00:00

abstract：PURPOSE:We located immunohistochemically the matrix metalloproteinases (MMP) -1, -2, -3 and -9 and the tissue inhibitors of matrix metalloproteinases (TIMP) -1 and -2 in the fibrous capsule of patients with intraocular lenses (IOLs). METHODS:During vitreoretinal surgery in 10 patients we obtained post-cataract surgery...

journal_title：Current eye research

authors： Kawashima Y,Saika S,Miyamoto T,Yamanaka O,Okada Y,Tanaka S,Ohnishi Y

更新日期：2000-12-01 00:00:00

abstract：AIM OF THE STUDY:The similarity of many benign intrabulbar lesions to a malignant tumor requires detailed differential diagnostics. However, none of the known methods can be used as the only one to determine the type of lesions. The aim of this study was to determine color Doppler imaging (CDI) markers characteristic o...

journal_title：Current eye research

authors： Modrzejewska M,Wiącek MP

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:To investigate the effects of pyrrolidine dithiocarbamate (PDTC), a nuclear factor κ-light-chain-enhancer of activated B cells (NF-κB) inhibitor, on the expression of matrix metalloproteinases (MMP) and MMP-mediated apoptosis in retinal ganglion cells (RGCs) following the transection of the optic nerve (ON) in ...

journal_title：Current eye research

authors： Sun MH,Chen KJ,Tsao YP,Kao LY,Han WH,Lin KK,Pang JH

更新日期：2011-11-01 00:00:00

abstract：:The distribution of a steroid antagonist, RU486, that is known to reduce rabbit intraocular pressure has been examined in the eye. On an equal tissue weight basis, the corneal epithelium is the site of maximal absorption followed by conjunctival tissues (bulbar and palpebral) and the rest of the cornea. Aqueous humor ...

journal_title：Current eye research

authors： Cheeks L,Green K

更新日期：1986-09-01 00:00:00

abstract：PURPOSE:The present study was conducted to develop and characterize a functional primary culture of pigmented rabbit conjunctival epithelial cells on permeable support exhibiting tight barrier properties. METHODS:Conjunctival epithelial cells were isolated by 0.2% protease treatment, cultured at 0.5-1.8 x 10(6) cells/...

journal_title：Current eye research

authors： Saha P,Kim KJ,Lee VH

更新日期：1996-12-01 00:00:00

abstract：PURPOSE:To evaluate the immediate effect of 3% diquafosol ophthalmic solution on tear MUC5AC concentration, periodic acid-Schiff (PAS)-positive goblet cells, and tear film stability in normal and keratoconjunctivitis sicca (KCS) rat models. METHODS:Rats were divided into normal and KCS groups. 3% of diquafosol solutio...

journal_title：Current eye research

authors： Choi KE,Song JS,Kang B,Eom Y,Kim HM

更新日期：2017-05-01 00:00:00

abstract：PURPOSE:There is a substantial literature showing that the selective estrogen receptor modulator tamoxifen can block swelling-activated chloride channels, such as those in astrocytes. This study aimed to test the hypothesis that anatomic characteristics consistent with swelling may be measured within the optic nerve he...

journal_title：Current eye research

authors： Eisner A,O'Malley JP,Incognito LJ,Toomey MD,Samples JR

更新日期：2006-04-01 00:00:00

abstract：:The ocular penetration pathways of three alpha 2-adrenergic agents (p-aminoclonidine, AGN 190342, and clonidine) were investigated in rabbits both in vitro and in vivo. The corneal permeabilities of the compounds correlated positively with their octanol/water distribution coefficients. The ocular drug absorption via c...

journal_title：Current eye research

authors： Chien DS,Homsy JJ,Gluchowski C,Tang-Liu DD

更新日期：1990-11-01 00:00:00