Controlled modulation of the phase separation and opacification temperature of purified bovine gamma IV-crystallin.

abstract：:The effect of cyclosporine (CsA) treatment in both primary and secondary Chlamydia trachomatis ocular infection in cynomolgus monkeys was studied. Following primary infection, CsA-treated animals developed severe clinical symptoms which persisted for up to 12 weeks compared to control animals which developed less seve...

journal_title：Current eye research

authors： Young E,Schachter J,Prendergast RA,Taylor HR

更新日期：1987-05-01 00:00:00

abstract：PURPOSE:Based on the relationship between keratoconus and dry eye, the aim of this study was to evaluate changes in signs and symptoms of dry eye in keratoconus patients before and after intrastromal corneal ring surgery. METHODS:Fifteen keratoconus patients were enrolled in Fundación Jiménez-Díaz of Madrid and Univer...

journal_title：Current eye research

authors： Carracedo G,Recchioni A,Alejandre-Alba N,Martin-Gil A,Batres L,Morote IJ,Pintor J

更新日期：2017-04-01 00:00:00

abstract：PURPOSE:Rhodopsin is a zinc-binding protein. We investigated the effect of low concentrations of zinc on the initial phosphorylation of rhodopsin. METHODS:Dark-adapted bovine rod outer segments (ROS) were incubated with (gamma 32P) ATP and 5 mM magnesium in the presence and absence of micromolar amounts of zinc. The R...

journal_title：Current eye research

authors： Shuster TA,Martin F,Nagy AK

更新日期：1996-10-01 00:00:00

abstract：PURPOSE:Maintaining mature and viable retinal pigment epithelial cells (RPE) in vitro has proven challenging. Investigating compounds that can promote RPE-viability and maturation is motivated by RPE transplantation research, the quest to understand RPE physiology, and a desire to modulate RPE in pathological states. W...

journal_title：Current eye research

authors： Khan AZ,Utheim TP,Moe MC,Aass HCD,Sapkota D,Vallenari EM,Eidet JR

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:Several procedures in cataract surgery carry the risk of high temperature increases in the capsular bag. The present study was undertaken to determine the shrinkage temperature of the human lens capsule and to investigate the effect of temperature on the mechanical behavior of the lens capsule. METHOD:Thermal-...

journal_title：Current eye research

authors： Krag S,Danielsen CC,Andreassen TT

更新日期：1998-05-01 00:00:00

abstract：:Spontaneous ocular shedding and adrenergic induction of ocular shedding were examined in rabbits infected with ten strains of herpes simplex virus type 1 (HSV-1): McKrae, KOS, F, Rodanus, 17 Syn+, RE, E-43, SC-16, MacIntyre, and CGA-3. All ocular inoculations were with 50 microliter of HSV-1 with titers between 1-10 X...

journal_title：Current eye research

authors： Hill JM,Rayfield MA,Haruta Y

更新日期：1987-01-01 00:00:00

abstract：:The effects of light damage were studied in four inbred strains of albino rats, Fischer (F344), Lewis (L), Wistar (W), and Buffalo (BUF). Thirty-five-day-old rats (3 from each strain) were kept in cyclic light for two weeks, after which they were exposed to constant fluorescent light (180-190 foot-candles, 490-580 nm)...

journal_title：Current eye research

authors： Borges JM,Edward DP,Tso MO

更新日期：1990-08-01 00:00:00

abstract：PURPOSE:To investigate retinal imaging and ablation using femtosecond laser pulses. MATERIALS AND METHODS:Two non-amplified near-infrared femtosecond lasers were used to irradiate porcine retinal specimens in vitro. The lasers were used for tissue removal as well as multiphoton laser scanning microscopy. RESULTS:Abla...

journal_title：Current eye research

authors： Hild M,Krause M,Riemann I,Mestres P,Toropygin S,Löw U,Brückner K,Seitz B,Jonescu-Cuypers C,König K

更新日期：2008-04-01 00:00:00

abstract：PURPOSE:Previously we established a strong association of systemic hypertension with cataract formation. In the present study, we investigated the role of nitric oxide (NO) in the development of cataract formation in CdCl2-induced hypertensive animals. MATERIALS AND METHODS:Hypertension was induced in male albino rats...

journal_title：Current eye research

authors： Yadav A,Choudhary R,Bodakhe SH

更新日期：2018-12-01 00:00:00

abstract：:Corneas and tendons dissected from 17-day-old chick embryos were labeled with [35S]methionine in the presence of 0.3 mM alpha,alpha'-dipyridyl. The unhydroxylated, 35S-labeled pro alpha chains and alpha chains were isolated by polyacrylamide gel electrophoresis in sodium dodecyl sulfate. The pro alpha and alpha chains...

journal_title：Current eye research

authors： Kao WW

更新日期：1985-02-01 00:00:00

abstract：:Specimens of a cornea, conjunctiva and iris were removed at the time of penetrating keratoplasty in a case of nephropathic cystinosis. Immunohistochemical studies revealed the presence of class II antigens on the stromal keratocytes of the cornea and the vascular endothelial cells, pericytes and fibroblasts of the con...

journal_title：Current eye research

authors： Kaiser-Kupfer MI,Chan CC,Rodrigues M,Datiles MB,Gahl WA

更新日期：1987-04-01 00:00:00

abstract：PURPOSE:To study the association of cell proliferation in uveal melanoma with the mean of the 10 largest nucleoli (MLN), microvascular prognostic factors, and survival. METHODS:Population-based, retrospective cohort study of 167 choroidal and ciliary body melanomas enucleated from 1972 to 1981. Mouse monoclonal antibo...

journal_title：Current eye research

authors： Al-Jamal RT,Kivelä T

更新日期：2006-01-01 00:00:00

abstract：:Vernier and grating acuity were measured in infants up to 6 months of age using a two-alternative forced-choice preferential looking technique. Vernier resolution was measured using a horizontal vernier grating. The grating was presented on half of the screen while the other half contained horizontal lines which were ...

journal_title：Current eye research

authors： Manny RE,Klein SA

更新日期：1984-03-01 00:00:00

abstract：:Hybridomas producing monoclonal antibodies to the retinal S antigen were obtained by fusion of spleen cells from a BALB/c mouse immunized with purified bovine S antigen and NS-1 myeloma cells. Six cloned hybridomas were selected and expanded as large scale cultures and as ascites in mice. The specificity of the antibo...

journal_title：Current eye research

authors： Faure JP,Mirshahi M,Dorey C,Thillaye B,de Kozak Y,Boucheix C

更新日期：1984-06-01 00:00:00

abstract：:Thrombospondins are a family of large multi-domain glycoproteins described as matricelluar proteins based on their ability to interact with a broad range of receptors, matrix molecules, growth factors or proteases, and to modulate array of cellular functions including intracellular signaling, proliferation and migrati...

journal_title：Current eye research

authors： Masli S,Sheibani N,Cursiefen C,Zieske J

更新日期：2014-08-01 00:00:00

abstract：PURPOSE:To compare the long-term outcomes and recurrence rate of extensive versus limited subconjunctival pterygium excision with conjunctival autograft. METHODS:This retrospective study included 135 consecutive patients (161 eyes) who had pterygium excision with conjunctival autograft at the cornea performed at the c...

journal_title：Current eye research

authors： Bahar I,Kaiserman I,Weisbrod M,McAllum P,Slomovic A

更新日期：2008-05-01 00:00:00

abstract：:Human endothelial morphologic changes were quantitated by specular microscopy and computer-assisted morphometry to establish normal baselines of various morphologic parameters. Cellular polymegethism and cellular pleomorphism increases with age, and normal baseline parameters are detailed. Furthermore, no significant ...

journal_title：Current eye research

authors： Yee RW,Matsuda M,Schultz RO,Edelhauser HF

更新日期：1985-06-01 00:00:00

abstract：PURPOSE:Avascular tissues can be used to identify antilymph- or antihemangiogenic factors. The human sclera-the outer covering layer of the eye, lacks lymphatic vessels and contains only a superficial network of blood vessels and was used here to identify endogenous antiangiogenic factors. METHODS:Expression levels of...

journal_title：Current eye research

authors： Schlereth SL,Karlstetter M,Hos D,Matthaei M,Cursiefen C,Heindl LM

更新日期：2019-02-01 00:00:00

abstract：:This study was conducted to determine the therapeutic efficacy of 3.0 mg/ml ciprofloxacin administered concurrently with one of two salts of prednisolone for the treatment of experimental pseudomonal keratitis. Rabbit corneas were injected intrastromally with Pseudomonas aeruginosa ATCC strain 27853. Sixteen hr after ...

journal_title：Current eye research

authors： Hobden JA,Engel LS,Hill JM,Callegan MC,O'Callaghan RJ

更新日期：1993-05-01 00:00:00

abstract：:The corneal endothelium is known to contain gap junctions on its lateral borders. Here we show that the endothelial cells of the rabbit cornea are highly dye coupled. Lucifer Yellow CH introduced into a single cell through either an intracellular glass microelectrode or a patch electrode rapidly spreads into its neigh...

journal_title：Current eye research

authors： Rae JL,Lewno AW,Cooper K,Gates P

更新日期：1989-08-01 00:00:00

abstract：PURPOSE:To assess the potential impact of corneal crosslinking treatment (365 nm ultraviolet (UV)A irradiation with riboflavin) on the material properties of Intracorneal Rings Segments (ICRS). MATERIALS AND METHODS:Material properties were studied using FT-IR spectroscopy and UV-Vis spectroscopy. Rings were examined:...

journal_title：Current eye research

authors： Sideroudi H,Labiris G,Soto-Beobide A,Voyiatzis G,Chrissanthopoulos A,Kozobolis V

更新日期：2015-05-01 00:00:00

abstract：:Goggles that degrade the retinal image produce axial enlargement of the ocular globe and large myopic refractive errors. Many authors have assumed that visual image degradation itself leads to myopia. Hodos and co-authors have shown, however, that goggled eyes in chicks are considerably warmer than normal. Such temper...

journal_title：Current eye research

authors： Shih YF,Fitzgerald ME,Norton TT,Gamlin PD,Hodos W,Reiner A

更新日期：1993-03-01 00:00:00

abstract：SIGNIFICANCE:Adopting a risk stratification system and appropriate listing of cases reduces the rates of intraoperative complications during phacoemulsification. Such listing would allow both safe surgery and enhance training, by ensuring an appropriately experienced surgeon is available to operate on a case or supervi...

journal_title：Current eye research

authors： Pooprasert P,Hansell J,Young-Zvandasara T,Muhtaseb M

更新日期：2020-07-30 00:00:00

abstract：:This study reports on serum interleukin 2-receptor (IL-2R) levels in uveitis patients. IL-2R is the mediator protein of interleukin 2 (IL-2), a mitogenetic cytokine of primarily immune cell interaction. Stimulated T-cells readily express IL-2R on their cell surface and release a soluble form into serum. The measuremen...

journal_title：Current eye research

authors： Arocker-Mettinger E,Asenbauer T,Ulbrich S,Grabner G

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:To compare the retinal sensitivity, using Microperimeter and the morphological changes in retinal layers, using Spectral Domain Optical Coherence Tomography (SD-OCT), between myopes and age-matched emmetropes. METHODS:Twenty-nine myopic eyes and 29 emmetropic eyes were enrolled in this prospective case control...

journal_title：Current eye research

authors： Gella L,Raman R,Sharma T

更新日期：2011-10-01 00:00:00

abstract：PURPOSE:To study the effect of Na-K pump and K(ATP) channel inhibition on the diameter and the adenosine-induced vasodilation of small retinal arterioles. METHODS:Thirty isolated porcine arterioles with a diameter of approximately 70 microm were mounted in a double-barrelled pipette system placed in an organ bath, and...

journal_title：Current eye research

authors： Jeppesen P,Aalkjaer C,Bek T

更新日期：2002-07-01 00:00:00

abstract：:The variation of central corneal thickness with age was measured weekly at 10am by ultrasound pachometry in 10 normal (5 to 19 weeks of age) and 10 alloxan-induced diabetic (9 to 19 weeks of age) rabbits. The diurnal variation of corneal thickness was also measured at 2 hour intervals for a period of 24 hours on both ...

journal_title：Current eye research

authors： Herse PR

更新日期：1990-05-01 00:00:00

abstract：:The mechanism of oxidative damage to the lens through intraocular photochemical generation of superoxide and its derivatization to other oxidants such as singlet oxygen, hydroxyl radical and hydrogen peroxide has been studied. Rat lenses when organ cultured aerobically in TC 199 containing additional amounts of ribofl...

journal_title：Current eye research

authors： Varma SD,Chand D,Sharma YR,Kuck JF Jr,Richards RD

更新日期：1984-01-01 00:00:00

abstract：PURPOSE:We recently demonstrated that direct subretinal (SR) injection of adeno-associated virus (AAV) type 8 (AAV8) into photoreceptor cells and retinal pigment epithelium (RPE) is a highly efficient model of gene delivery. The current study compared transduction efficiency and expression patterns associated with vari...

journal_title：Current eye research

authors： Igarashi T,Miyake K,Asakawa N,Miyake N,Shimada T,Takahashi H

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:To investigate the relationship between meibomian gland dysfunction (MGD) and incomplete blinking caused by cranial nerve seven (CN VII) palsy. METHODS:A prospective case series of 60 consecutive patients with unilateral CN VII palsy was evaluated for MGD. According to the House-Brackmann scale, patients were ...

journal_title：Current eye research

authors： Wan T,Jin X,Lin L,Xu Y,Zhao Y

更新日期：2016-01-01 00:00:00