Higher protein intake increases cardiac function parameters in healthy children: metabolic programming by infant nutrition-secondary analysis from a clinical trial.

abstract：BACKGROUND:Infantile hemangioma (IH) is the most frequent vascular tumor of early childhood. Recently, propranolol, a nonselective β1- and β2-adrenoceptor inhibitor, was introduced into the therapy of severe proliferating IH with excellent results. However, the underlying mechanism of action of propranolol is still unc...

journal_title：Pediatric research

authors： Rössler J,Haubold M,Gilsbach R,Jüttner E,Schmitt D,Niemeyer CM,Hein L

更新日期：2013-04-01 00:00:00

abstract：:Previous studies have demonstrated that myocardial function changes during mammalian perinatal development. The purpose of this study was to evaluate the subcellular basis underlying the slower relaxation in the developing heart by examining perinatal changes in sarcoplasmic reticulum (SR) function, and in SR Ca2+ pum...

journal_title：Pediatric research

authors： Fisher DJ,Tate CA,Phillips S

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:Earlier identification of children with prenatal alcohol exposure (PAE) remains a challenge. The objective of this study was to identify neurobehavioral (NB) outcomes associated with PAE in infants. METHODS:This manuscript evaluates NB outcomes at 6.33±1.12 months of age in 93 infants (39 PAE and 54 No-PAE)...

journal_title：Pediatric research

authors： Bakhireva LN,Lowe J,Garrison LM,Cano S,Leyva Y,Qeadan F,Stephen JM

更新日期：2018-09-01 00:00:00

abstract：:The effects of an emulsified intravenous fat preparation (Intralipid) on bilirubin transport were analyzed by cholestyramine extraction, spectrophotometric analysis, Sephadex gel filtration, peroxidase assay, bilirubin uptake by red blood cells, and by toxicity in tissue culture (L-929) cells. Intralipid is capable of...

journal_title：Pediatric research

authors： Thaler MM,Wennberg RP

更新日期：1977-03-01 00:00:00

abstract：:A patient is reported who presented in the newborn period with an unusual combination of congenital lactic acidosis and bilateral calcifications in the adrenal medulla, visible on standard abdominal x-ray and ultrasound examination. At birth, the proband was hypotonic and dystrophic. She developed respiratory insuffic...

journal_title：Pediatric research

authors： Zecic A,Smet JE,De Praeter CM,Vanhaesebrouck P,Viscomi C,Van Den Broecke C,De Paepe B,Lohse P,Martin JJ,Jackson JG,Campbell CR,De Meirleir LJ,Zeviani M,Seneca SH,Lissens W,Van Coster RN

更新日期：2009-09-01 00:00:00

abstract：:Cell-mediated immunity is not well characterized in very low birth weight infants, and abnormalities may represent a significant vulnerability to infection. This report describes 165 serial studies in 58 infants between 700 and 1300 g birth weight during the first 8 wk of life. Two ml of blood were drawn at 2-wk inter...

journal_title：Pediatric research

authors： Bussel JB,Cunningham-Rundles S,LaGamma EF,Shellabarger M

更新日期：1988-05-01 00:00:00

abstract：:Our aim was to obtain a better understanding of the differences between breast-feeding and bottle-feeding, particularly with regard to how sucking performance changes from nonnutritive sucking (NNS) to nutritive sucking (NS). Twenty-two normal term infants were studied while breast-feeding at 4 and 5 d postpartum. Fiv...

journal_title：Pediatric research

authors： Mizuno K,Ueda A

更新日期：2006-05-01 00:00:00

abstract：:The cerebral metabolic effects of hypoglycemia due to intrauterine growth retardation were studied in newborn dogs. Intrauterine growth retardation was induced in newborn dogs after 3 days of maternal nutritional deprivation (birth weight 251 +/- 7 versus 227 +/- 7 g, p less than 0.01). After birth, growth retarded pu...

journal_title：Pediatric research

authors： Kliegman RM

更新日期：1988-11-01 00:00:00

abstract：:The length of the Y chromosome was measured in 42 black patients with trisomy 21 (47,XY,+21) and a similar number of normal individuals of American black ancestry. The length of the Y was expressed as a function of Y/F ratio and arbitrarily classified into five groups using subjectively defined criteria as follows: ve...

journal_title：Pediatric research

authors： Verma RS,Huq A,Madahar C,Qazi Q,Dosik H

更新日期：1982-09-01 00:00:00

abstract：:Early-onset neonatal group B beta-hemolytic streptococcus (GBS) infection exhibits pathophysiologic characteristics of a toxic shock syndrome, in which a cascade of inflammatory mediators are involved. Thromboxane A2 (TXA2) is thought to play an important role as a mediator of the pulmonary response to GBS toxin, beca...

journal_title：Pediatric research

authors： Sandberg K,Edberg KE,Fish W,Parker RA,Hellerqvist C,Sundell H

更新日期：1994-05-01 00:00:00

abstract：:This study aimed to investigate 1) the plasma resistin concentration at birth, 2) the relationship of resistin with leptin and insulin, and 3) the association of resistin with anthropometric indexes in newborn infants. Blood samples for hormonal assay were obtained from preterm and term newborns within the first 2 h o...

journal_title：Pediatric research

authors： Ng PC,Lee CH,Lam CW,Chan IH,Wong E,Fok TF

更新日期：2005-10-01 00:00:00

abstract：:The aim of this study was to evaluate the changes in Doppler transmitral flow patterns during the 1st d of life. Doppler echocardiography of the ascending aorta and mitral valve was performed serially in 20 normal neonates at 2, 12, and 24 h of age. A computer-interfaced digitizer pad was used to measure the following...

journal_title：Pediatric research

authors： Harada K,Shiota T,Takahashi Y,Tamura M,Toyono M,Takada G

更新日期：1994-04-01 00:00:00

abstract：:Sodium deficiency is associated with decreased muscle growth and protein synthesis. We investigated the influence of diet-induced sodium deficiency on the rate and extent of compensatory growth of the right lung after left pneumonectomy in young rats of 83 +/- 1 g body weight. Starting 1 wk before surgery, all rats we...

journal_title：Pediatric research

authors： Gallaher KJ,Wolpert E,Wassner S,Rannels DE

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Risk factors for diastolic dysfunction in hypertrophic cardiomyopathy (HCM) are poorly understood. We investigated the association of variants in hypoxia-response genes with phenotype severity in pediatric HCM. METHODS:A total of 80 unrelated patients <21 y and 14 related members from eight families with HC...

journal_title：Pediatric research

authors： Alkon J,Friedberg MK,Manlhiot C,Manickaraj AK,Kinnear C,McCrindle BW,Benson LN,Addonizio LJ,Colan SD,Mital S

更新日期：2012-12-01 00:00:00

abstract：:Data are scarce regarding mineral bioavailability from human milk in older infants who may also be receiving solid foods (beikost). We measured the absorption of Ca, Zn, and Fe in 14 healthy, nonanemic 5-7-mo-old breast-fed infants whose mothers milk was extrinsically labeled with stable isotopes (44Ca, 70Zn, and 58Fe...

journal_title：Pediatric research

authors： Abrams SA,Wen J,Stuff JE

更新日期：1997-03-01 00:00:00

abstract：:Aspiration is a major cause of lung disease in infants and young children. As the symptoms and signs of aspiration are not specific, the diagnosis is delayed due to a low index of suspicion and low sensitivity and specificity of the available diagnostic tests. In the present study, we evaluated the utility of microsph...

journal_title：Pediatric research

authors： Springer C,Benita S,Sherman Y,Gursoy N,Gilhar D,Avital A

更新日期：2005-09-01 00:00:00

abstract：:Irreversible congenital heart block (CHB) and the transient rash of neonatal lupus are strongly associated with maternal antibodies to SSA/Ro and SSB/La proteins; however, the precise mechanism by which these antibodies mediate organ-specific injury is not yet defined. Culturing of keratinocytes has provided critical ...

journal_title：Pediatric research

authors： Tseng CE,Miranda E,Di Donato F,Boutjdir M,Rashbaum W,Chan EK,Buyon JP

更新日期：1999-02-01 00:00:00

abstract：:In artificial tubes as well as in blood vessels with diameters less than 500 microns, blood viscosity decreases with decreasing diameter (Fahraeus-Lindqvist effect). Our study measured viscosity of red blood cells (RBC) from 10 preterm infants, 10 term neonates, and 10 adults by means of a capillary viscometer. RBC we...

journal_title：Pediatric research

authors： Zilow EP,Linderkamp O

更新日期：1989-06-01 00:00:00

abstract：:The regionalization of pediatric services has resulted in differential access to care, sometimes creating barriers to those living in underserved, rural communities. These disparities in access contribute to inferior healthcare outcomes among infants and children. We review the medical literature on telemedicine and i...

journal_title：Pediatric research

authors： Marcin JP,Shaikh U,Steinhorn RH

更新日期：2016-01-01 00:00:00

abstract：:To evaluate the maturation of glucose homeostasis in the small for gestational age (SGA) neonate, glucose kinetics were measured with 78% enriched D-[U-13C]glucose by the prime plus constant infusion technique in nine SGA infants and compared with the rate obtained in seven term appropriate for gestational age infants...

journal_title：Pediatric research

authors： Cowett RM,Susa JB,Oh W,Schwartz R

更新日期：1984-01-01 00:00:00

abstract：INTRODUCTION:The Coulter LH780 hematology analyzer can evaluate mean neutrophil volume (MNV), conductivity (MNC), scatter (MNS), and distribution width (DW). We sought to investigate the value of volume, conductivity, and scatter (VCS) parameters in diagnosis and treatment efficacy of neonatal sepsis. RESULTS:We obser...

journal_title：Pediatric research

authors： Celik IH,Demirel G,Aksoy HT,Erdeve O,Tuncer E,Biyikli Z,Dilmen U

更新日期：2012-01-01 00:00:00

abstract：:Newborn Sprague-Dawley rat pups were found to have reduced net tubular reclamation of the beta-amino acid taurine in vivo. The reabsorption of this compound increased between the 2nd and 4th week of life and the excreted taurine fell despite a rise in glomerular filtration rate indicative of increased transport with m...

journal_title：Pediatric research

authors： Chesney RW,Jax DK

更新日期：1979-07-01 00:00:00

abstract：:The transport of phosphate into jejunal brush border membrane vesicles isolated from 14- to 42-day-old rats was investigated using a rapid filtration technique. The presence of a sodium gradient enhanced phosphate uptake at all ages. Both sodium-dependent phosphate uptake and passive phosphate uptake declined with inc...

journal_title：Pediatric research

authors： Borowitz SM,Ghishan FK

更新日期：1985-12-01 00:00:00

abstract：:Increased concentrations of carcinoembryonic antigen (CEA) have been reported in the sera and sputum of patients with cystic fibrosis. We have found significantly higher concentrations of CEA in both extracted and unextracted saliva of patients with cystic fibrosis compared to age-matched controls and a comparable gro...

journal_title：Pediatric research

authors： MacSween JM,Gillespie CT

更新日期：1980-03-01 00:00:00

abstract：:Ventilation of immature airways has been shown to result in pressure-induced deformation and alteration of mechanical properties. These changes in mechanical properties may alter the effect of compressive pressures on pressure-flow relationships. To test this hypothesis, unventilated (Group I, n = 8) and ventilated (g...

journal_title：Pediatric research

authors： Penn RB,Wolfson MR,Shaffer TH

更新日期：1988-05-01 00:00:00

abstract：:Defective arousal mechanisms are viewed as contributory to sleep hypopnea disorders and sudden infant death syndrome. Sighs (i.e. augmented breaths) as well as startles have not traditionally been viewed as arousal-related phenomena in infants. We hypothesized that, if sighs and startles are the initial event in a seq...

journal_title：Pediatric research

authors： Wulbrand H,McNamara F,Thach BT

更新日期：1998-11-01 00:00:00

abstract：:Recently a soybean oil emulsion (Intralipid) (IL) has been released in the United States for use as a parenteral nutrient. The study reported here was undertaken to determine the effect of ingestion of IL on the synthesis and secretion of the second (C2) and fourth (C4) components of complement by guinea pig peritonea...

journal_title：Pediatric research

authors： Strunk RC,Kunke K,Nagle RB,Payne CM,Harrison HR

更新日期：1979-03-01 00:00:00

abstract：:An animal study to evaluate dual-energy x-ray absorptiometry (DXA) and magnetic resonance (MR) imaging and spectroscopy for measurement of neonatal body composition was performed. Twenty-three piglets with body weights ranging from 848 to 7550 g were used. After measuring total body water, animals were killed and body...

journal_title：Pediatric research

authors： Fusch C,Slotboom J,Fuehrer U,Schumacher R,Keisker A,Zimmermann W,Moessinger A,Boesch C,Blum J

更新日期：1999-10-01 00:00:00

abstract：:The purpose of this investigation was to determine whether maximal oxygen consumption (VO2max) differed between clinically obese black and white children and if a difference existed to determine whether it was related to hematological profiles and/or physical activity/inactivity levels. Twenty-three black and 21 white...

journal_title：Pediatric research

authors： Andreacci JL,Robertson RJ,Dubé JJ,Aaron DJ,Dixon CB,Arslanian SA

更新日期：2005-09-01 00:00:00

abstract：:In mice, secondary alveolar septal formation primarily occurs during a brief postnatal period and is accompanied by transient expansion of the interstitial lung fibroblast (LF) population. PDGF-A, which solely signals through PDGF-receptor-alpha (PDGF-Rα), is required for expansion, but the receptor's relevant downstr...

journal_title：Pediatric research

authors： McGowan SE,McCoy DM

更新日期：2011-07-01 00:00:00