Resistin in preterm and term newborns: relation to anthropometry, leptin, and insulin.

abstract：BACKGROUND:Adult human airway smooth muscle (ASM) produce cytokines involved in recruitment and survival of leukocytes within airway walls. Cytokine generation by adult ASM is glucocorticoid-sensitive. Whether developing lung ASM produces cytokines in a glucocorticoid-sensitive fashion is unknown. METHODS:Cultured fet...

journal_title：Pediatric research

authors： Pearson H,Britt RD Jr,Pabelick CM,Prakash YS,Amrani Y,Pandya HC

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Increasing numbers of preterm-born children survive nowadays, and improving long-term health and neurodevelopment is becoming more important. Early-life growth has been linked to neurodevelopmental outcomes. We aimed to study whether this association has changed with time. METHODS:We studied two cohorts of ...

journal_title：Pediatric research

authors： Ruys CA,Hollanders JJ,Bröring T,van Schie PEM,van der Pal SM,van de Lagemaat M,Lafeber HN,Rotteveel J,Finken MJJ

更新日期：2019-02-01 00:00:00

abstract：:Indomethacin is used to constrict the patent ductus arteriosus in premature infants. To clarify possible prostanoid receptor antagonists that can constrict the ductus, we studied in vivo constriction of the fetal and neonatal ductus arteriosus by AE3-208, a prostanoid EP4-receptor antagonist, in rats. Following quick ...

journal_title：Pediatric research

authors： Momma K,Toyoshima K,Takeuchi D,Imamura S,Nakanishi T

更新日期：2005-11-01 00:00:00

abstract：:Leukotrienes C4 and D4 and thromboxane A2 are potent vasoconstrictors that may mediate pulmonary vasoconstriction in many clinical situations. There is a complex interaction among leukotrienes and thromboxane A2, because inhibition of thromboxane synthesis prevents some of the hemodynamic effects of exogenous leukotri...

journal_title：Pediatric research

authors： Soifer SJ,Schreiber MD,Heymann MA

更新日期：1989-08-01 00:00:00

abstract：:Preterm infants are prone to abnormal bacterial colonization of the intestine with ensuing adverse health effects. To examine whether the oral application of Bifidobacterium lactis Bb12 (probiotic) may improve selected indicators of health status in preterm infants, a double blind, placebo controlled randomized clinic...

journal_title：Pediatric research

authors： Mohan R,Koebnick C,Schildt J,Mueller M,Radke M,Blaut M

更新日期：2008-10-01 00:00:00

abstract：:Prematurity is associated with delayed postnatal activation of mitochondrial oxidative phosphorylation and impaired switch from glycolytic to oxidative metabolism. Fatty acids (FA), which represent a major energy substrate in mature muscle cells, are engaged in the postnatal activation of genes of energy metabolism an...

journal_title：Pediatric research

authors： Brauner P,Kopecký P,Flachs P,Ruffer J,Sebron V,Plavka R,Vítková I,Vorlícek J,Kopecký J

更新日期：2003-04-01 00:00:00

abstract：:Insulin is a potent mitogen for many cell types in vitro. During tissue culture, supraphysiological concentrations of insulin are necessary to promote cell replication in connective or musculoskeletal tissues. Insulin promotes the growth of these cells by binding, with low affinity, to the type I insulin-like growth f...

journal_title：Pediatric research

authors： Hill DJ,Milner RD

更新日期：1985-09-01 00:00:00

abstract：:Platelet-activating factor (PAF) is a proinflammatory phospholipid mediator implicated in necrotizing enterocolitis. Regulation of PAF-acetylhydrolase (AH), the enzyme degrading PAF, is poorly understood. In this study we found that administration of a dose of PAF (1.5 microg/kg, i.v.), which does not cause gross inte...

journal_title：Pediatric research

authors： Wang H,Tan XD,Qu XW,Chang H,Remick DG,Gonzalez-Crussi F,Hsueh W

更新日期：1997-11-01 00:00:00

abstract：:Kawasaki disease (KD) is an acute vasculitis of young childhood predominantly affecting the coronary arteries. IgA plasma cells have been found to infiltrate vascular and nonvascular tissues in fatal acute KD. To determine whether IgA B-lymphocytes were increased in the peripheral blood of patients with KD, we perform...

journal_title：Pediatric research

authors： Shingadia D,O'Gorman M,Rowley AH,Shulman ST

更新日期：2001-10-01 00:00:00

abstract：:We used in vivo microdialysis to determine the impact of a focal hypoxic-ischemic insult on hippocampal amino acid efflux in the immature brain. Microdialysis probes were inserted into the right hippocampus of postnatal d 7 rats. To induce hypoxic-ischemic injury, the right carotid artery was ligated and animals were ...

journal_title：Pediatric research

authors： Silverstein FS,Naik B,Simpson J

更新日期：1991-12-01 00:00:00

abstract：:A comparative study of two smallpox vaccines, standard calf lymph vaccine, and an attenuated vaccine, CVI-78, was performed in 95 children. Primary vaccination with CVI-78 resulted in a more attenuated response than primary vaccination with standard vaccine. Sixty-one percent of those vaccinated with CVI-78 and 96 per...

journal_title：Pediatric research

authors： Wesley RB,Speers WC,Neff JM,Ruben FL,Lourie B

更新日期：1975-08-01 00:00:00

abstract：:Blood mononuclear cells from newborns and from adults, immune or nonimmune to herpes simplex virus, were cultured with IL 2 and herpes simplex virus and the amount of gamma-interferon in the supernatant measured after 3 days. The newborn and nonimmune adult cells made equivalent trace amounts of gamma-interferon in cu...

journal_title：Pediatric research

authors： Hayward AR,Herberger M,Saunders D

更新日期：1986-05-01 00:00:00

abstract：:Music is widely used to enhance well-being. We wished to assess music's effect on pediatric oncology outpatients. Patients who had leukemia and were in maintenance or consolidation outpatient treatment served as their own control at two visits. At visit 1, children rested for 20 min; at visit 2, for 20 min they listen...

journal_title：Pediatric research

authors： Kemper KJ,Hamilton CA,McLean TW,Lovato J

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:A growing body of evidence defines inflammation as a hallmark feature of disease pathogenesis of Duchenne muscular dystrophy. To tailor potential immune modulatory interventions, a better understanding of immune dysregulation in Duchenne muscular dystrophy is needed. We now asked whether dystrophin deficienc...

journal_title：Pediatric research

authors： Kranig SA,Tschada R,Braun M,Patry C,Pöschl J,Frommhold D,Hudalla H

更新日期：2019-08-01 00:00:00

abstract：:Although the pathogenesis of necrotizing enterocolitis remains uncertain, ischemia appears to be an important contributing factor to the development of this disorder. Reperfusion plays a major role in ischemia-related injury, and oxygen free radicals produced during reperfusion most likely contribute to the injury. Th...

journal_title：Pediatric research

authors： Papparella A,DeLuca FG,Oyer CE,Pinar H,Stonestreet BS

更新日期：1997-08-01 00:00:00

abstract：:The interrelationship of 2,3-diphosphoglycerate (2,3-DPG) and P50 levels during the fetal and postnatal life were determined in two mammalian species which do not have a switchover of hemoglobin type at the end of their fetal development. In the guinea pig and rabbit, the 2,3-DPG levels remain low during fetal life an...

journal_title：Pediatric research

authors： Bard H,Shapiro M

更新日期：1979-03-01 00:00:00

abstract：:The ability of intravenously administered glucose or glucose oligosaccharides to supply 12% of the energy requirement of the growing miniature pig was determined. All pigs were fed a stock diet from days 5-28 of life, and a central venous catheter was inserted at 29 days. For the next 30 days, all pigs were fed both e...

journal_title：Pediatric research

authors： Andersen DW,Filer LJ Jr,Wu-Rideout YC,White LB,Stegink LD

更新日期：1982-04-01 00:00:00

abstract：BACKGROUND:Exposure to inflammation exacerbates injury in neonatal encephalopathy (NE). We hypothesized that brain biomarker mRNA, cytokine mRNA and microRNA differentiate inflammation (E. coli LPS), hypoxia (Hypoxia), and inflammation-sensitized hypoxia (LPS+Hypoxia) in an NE piglet model. METHODS:Sixteen piglets wer...

journal_title：Pediatric research

authors： Lingam I,Avdic-Belltheus A,Meehan C,Martinello K,Ragab S,Peebles D,Barkhuizen M,Tann CJ,Tachtsidis I,Wolfs TGAM,Hagberg H,Klein N,Fleiss B,Gressens P,Golay X,Kramer BW,Robertson NJ

更新日期：2020-06-10 00:00:00

abstract：BACKGROUND:Bronchopulmonary dysplasia (BPD) is an important cause of morbidity. The aim of this study was to evaluate the preventive effect of cytidine 5'-diphosphocholine (CDP-choline) treatment on hyperoxic lung injury in a neonatal rat model. METHODS:A total of 30 newborn pups were divided into control, hyperoxia, ...

journal_title：Pediatric research

authors： Cetinkaya M,Cansev M,Kafa IM,Tayman C,Cekmez F,Canpolat FE,Tunc T,Sarici SU

更新日期：2013-07-01 00:00:00

abstract：:Congenital Central Hypoventilation Syndrome (CCHS) patients show partial retention of peripheral chemoreception despite impaired ventilatory responses to CO2 and hypoxia. The condition allows examination of central responses to hyperoxia, which minimizes afferent traffic from peripheral chemoreceptors. We used functio...

journal_title：Pediatric research

authors： Woo MA,Macey PM,Macey KE,Keens TG,Woo MS,Harper RK,Harper RM

更新日期：2005-04-01 00:00:00

abstract：:Cerebral malaria is the most severe neurological complication of infection with Plasmodium falciparum. With >575,000 cases annually, children in sub-Saharan Africa are the most affected. Surviving patients have an increased risk of neurological and cognitive deficits, behavioral difficulties, and epilepsy making cereb...

journal_title：Pediatric research

authors： Idro R,Marsh K,John CC,Newton CR

更新日期：2010-10-01 00:00:00

abstract：:In order to study the neonatal microcirculation, the capillary hemodynamics in skin was investigated in 43 full-term infants 2-7 days after birth. The nailfold capillaries of the thumb were visualized by means of television microscopy and the capillary blood cell velocity (CBV) was videophotometrically quantified in 1...

journal_title：Pediatric research

authors： Norman M,Herin P,Fagrell B,Zetterström R

更新日期：1988-06-01 00:00:00

abstract：:We probed possible developmentally related changes in thin filament activity in rat hearts with the aid of calmidazolium (CDZ). CDZ is a calmodulin antagonist that also binds to troponin C and stimulates Ca2+ troponin C-dependent activation of cardiac myofibrillar contractile activity. In paired experiments, we compar...

journal_title：Pediatric research

authors： Murphy AM,Solaro RJ

更新日期：1990-07-01 00:00:00

abstract：:We determined the concentrations of copper, the activities of ceruloplasmin and peptidylglycine alpha-amidating monooxygenase (PAM), and the stimulation index of PAM by the in vitro addition of copper in plasma samples obtained from three male patients with occipital horns and a milder Menkes disease phenotype, having...

journal_title：Pediatric research

authors： Prohaska JR,Tamura T,Percy AK,Turnlund JR

更新日期：1997-12-01 00:00:00

abstract：:BackgroundSpecific HLA-DQ genes have been recognized as necessary - but not sufficient - factors for the occurrence of Celiac Disease (CD). Through a meta-analysis, evaluating the distribution of CD-related HLA genotypes in children, we aimed at providing insights for a potential widened screening strategy.MethodsAfte...

journal_title：Pediatric research

authors： De Silvestri A,Capittini C,Poddighe D,Valsecchi C,Marseglia G,Tagliacarne SC,Scotti V,Rebuffi C,Pasi A,Martinetti M,Tinelli C

更新日期：2018-03-01 00:00:00

abstract：:Previous studies suggest that the endotoxin lipopolysaccharide (LPS) may have dual effects on brain damage induced by hypoxia-ischemia (HI) in 7-d-old rats, depending on the exposure paradigm. Although a 4-h interval between LPS administration and HI results in sensitization to HI brain injury, tolerance is observed w...

journal_title：Pediatric research

authors： Ikeda T,Yang L,Ikenoue T,Mallard C,Hagberg H

更新日期：2006-01-01 00:00:00

abstract：:Perinatal brain injury is a leading cause of death and disability in young children. Recent advances in obstetrics, reproductive medicine and neonatal intensive care have resulted in significantly higher survival rates of preterm or sick born neonates, at the price of increased prevalence of neurological, behavioural ...

journal_title：Pediatric research

authors： Bendix I,Hadamitzky M,Herz J,Felderhoff-Müser U

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Later life metabolic dysfunction is a well-recognized consequence of being born small for gestational age (SGA). This study has applied metabolomics to identify whether there are changes in these pathways in prepubertal short SGA children and aimed to compare the intracellular and extracellular metabolome in...

journal_title：Pediatric research

authors： Murray PG,Butcher I,Dunn WB,Stevens A,Perchard R,Hanson D,Whatmore A,Westwood M,Clayton PE

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:The objective was to determine the association between perioperative risk factors and brain imaging abnormalities on neurologic outcome in neonates with hypoplastic left heart syndrome (HLHS) or d-Transposition of the great arteries (d-TGA) who underwent cardiac surgery including cardiopulmonary bypass. MET...

journal_title：Pediatric research

authors： Kuhn VA,Carpenter JL,Zurakowski D,Reitz JG,Tague L,Donofrio MT,Murnick J,Axt-Fliedner R,Limperopoulos C,Yerebakan C

更新日期：2020-07-25 00:00:00

abstract：:Studies using stable isotopically labeled glucose and palmitate as precursors of pulmonary surfactant synthesis have demonstrated slow surfactant turnover in premature infants with respiratory distress syndrome (RDS). However, only limited data about surfactant turnover are available for term infants. Because acetate ...

journal_title：Pediatric research

authors： Bohlin K,Merchak A,Spence K,Patterson BW,Hamvas A

更新日期：2003-08-01 00:00:00