Early-life growth of preterm infants and its impact on neurodevelopment.

abstract：:Fetuin-A prevents tissue calcification by forming soluble complexes with calcium and phosphate. A pathological depletion of serum fetuin-A has been observed in children on dialysis or after renal transplantation but knowledge on physiologic age-related changes in serum fetuin-A is limited. We prospectively evaluated s...

journal_title：Pediatric research

authors： Häusler M,Schäfer C,Osterwinter C,Jahnen-Dechent W

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Near-infrared spectroscopy is used in the assessment of regional splanchnic oxygen saturation (rsSO2), but solid reference values are scarce. We aimed to establish reference values of rsSO2 for preterm infants during the first week after birth, both crude and modeled based on predictors. METHODS:We included...

journal_title：Pediatric research

authors： van der Heide M,Dotinga BM,Stewart RE,Kalteren WS,Hulscher JBF,Reijneveld SA,Bos AF,Kooi EMW

更新日期：2021-01-27 00:00:00

abstract：:Factors, such as insulin, found in human and pig colostrum and mature milk likely influence small intestinal growth and development. Although pharmacologic doses of insulin injected parenterally may accelerate small intestinal development in altricial animals such as the rodent, the effects of oral insulin on intestin...

journal_title：Pediatric research

authors： Shulman RJ

更新日期：1990-08-01 00:00:00

abstract：:An important feature of the role of IgA in protection against infection and disease at the level of the mucosal surfaces might be the elimination of pathogens without induction of a strong inflammatory reaction. In the present study we addressed the question whether IgA has a regulatory effect on the generation of rea...

journal_title：Pediatric research

authors： Wolf HM,Vogel E,Fischer MB,Rengs H,Schwarz HP,Eibl MM

更新日期：1994-08-01 00:00:00

abstract：:Early-life stress has been shown to destabilize the homeostatic synaptic plasticity and compromise the developing brain to the later encountered insults. This study would determine the long-term epileptogenic effect of neonatal isolation (NI) on early-life seizure. There were five groups: normal rearing (NR) rats; NI ...

journal_title：Pediatric research

authors： Lai MC,Lui CC,Yang SN,Wang JY,Huang LT

更新日期：2009-10-01 00:00:00

abstract：:The use of tissue engineering to develop new urinary bladder could have direct impact on children suffering from congenital bladder dysfunction. Current bladder tissue engineering protocols rely on scaffolds to support the ingrowth of new cells and the subsequent development of new tissues. The interaction between cel...

journal_title：Pediatric research

authors： Roth CC

更新日期：2010-05-01 00:00:00

abstract：:Shigellosis in children can cause growth retardation, worsening of malnutrition, and hypoproteinemia. To assess the effects of ingestion of a protein-rich diet during convalescence, 22 children aged 2 to 4 y with culture-proven shigellosis were randomly assigned after 5 d of antibiotic treatment to 21-d feeding regime...

journal_title：Pediatric research

authors： Kabir I,Butler T,Underwood LE,Rahman MM

更新日期：1992-12-01 00:00:00

abstract：:Congenital Central Hypoventilation Syndrome (CCHS) patients show partial retention of peripheral chemoreception despite impaired ventilatory responses to CO2 and hypoxia. The condition allows examination of central responses to hyperoxia, which minimizes afferent traffic from peripheral chemoreceptors. We used functio...

journal_title：Pediatric research

authors： Woo MA,Macey PM,Macey KE,Keens TG,Woo MS,Harper RK,Harper RM

更新日期：2005-04-01 00:00:00

abstract：:To determine whether epidermal growth factor (EGF) or EGF-like transforming growth factors (TGFs) are present in ovine fetal tissues, we have tested acid-ethanol extracts of ovine fetal kidney for the ability to induce anchorage-independent growth of normal rat kidney fibroblasts in soft agar and to compete with 125I-...

journal_title：Pediatric research

authors： Freemark M,Comer M

更新日期：1987-11-01 00:00:00

abstract：:Data are scant regarding the development of cerebrovascular autoregulation in intrauterine growth-restricted (IUGR) newborns. We tested the hypothesis that IUGR improves the ability of neonates to withstand critical periods of gradual hemorrhagic hypotension by optimizing cerebrovascular autoregulation. Studies were c...

journal_title：Pediatric research

authors： Bauer R,Walter B,Vollandt R,Zwiener U

更新日期：2004-10-01 00:00:00

abstract：:Catecholamines (CA) are released from and resynthesized in the adrenal medulla in response to stress. In the mature animal, stimulus-secretion-synthesis coupling occurs through transsynaptic (neuronal) activity. In contrast, in the immature animal, before functional adrenal innervation, certain stressors (hypoglycemia...

journal_title：Pediatric research

authors： DeCristofaro JD,LaGamma EF

更新日期：1994-12-01 00:00:00

abstract：:The syndrome of hypoxemia-related myocardial dysfunction in the newborn is generally associated with severe intrapartum asphyxia. We investigated the changes in total and regional distribution of myocardial blood flow (MBF) that occur during asphyxia and the factors that regulate MBF, in the chronically prepared, near...

journal_title：Pediatric research

authors： Davies JM,Tweed WA

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND:Short-bowel syndrome (SBS) is the most common cause of neonatal intestinal failure. Recovery requires intestinal adaptation, dependent on enteral nutrition (EN) and growth factors such as glucagon-like peptide-2 (GLP-2), which is secreted from L cells in the ileum. Neonatal SBS often results in loss of ileum...

journal_title：Pediatric research

authors： Hua Z,Turner JM,Sigalet DL,Wizzard PR,Nation PN,Mager DR,Ball RO,Pencharz PB,Wales PW

更新日期：2013-06-01 00:00:00

abstract：:Recent studies have shown 1,25(OH)2D3 receptor-mediated modulation of leukocyte proliferation, differentiation, and function. We examined the phagocytosis and killing of microorganisms by neutrophils and monocytes from five patients of three families with hereditary resistance to 1,25(OH)2D3. Phagocytosis of microorga...

journal_title：Pediatric research

authors： Etzioni A,Hochberg Z,Pollak S,Meshulam T,Zakut V,Tzehoval E,Keisari Y,Aviram I,Spirer Z,Benderly A

更新日期：1989-03-01 00:00:00

abstract：:Necrotizing enterocolitis (NEC) is a devastating intestinal disease of premature infants. Maternal milk has been suggested to be partially protective against NEC; however, the mechanisms of this protection are not defined. The aim of this study was to examine the effect(s) of artificial feeding of rat milk (RM)-versus...

journal_title：Pediatric research

authors： Dvorak B,Halpern MD,Holubec H,Dvorakova K,Dominguez JA,Williams CS,Meza YG,Kozakova H,McCuskey RS

更新日期：2003-03-01 00:00:00

abstract：:The activity of galactose-1-phosphate uridyltransferase (transferase) and galactokinase in several organs from human fetuses 7-28 weeks old was measured by using radioactive substrates and column chromatography for product identification. The specific activity of transferase and galactokinase increased with gestationa...

journal_title：Pediatric research

authors： Shin-Buehring YS,Beier T,Tan A,Osang M,Schaub J

更新日期：1977-10-01 00:00:00

abstract：:Evaluation of nonlinear heart rate (HR) dynamics has received considerable attention in the pediatric literature because such analyses not only provide insight into underlying control mechanisms, but may also help to differentiate between normal and abnormal infants. The purpose of this study was to determine, in eigh...

journal_title：Pediatric research

authors： Mooney DM,Groome LJ,Holland SB,Smith YD

更新日期：1998-07-01 00:00:00

abstract：:Studies have shown that human neonates who develop group B streptococcal sepsis usually lack opsonic antibody (Ab) to their infecting strain and that these neonates may also have impaired polymorphonuclear leukocyte (PMN) function. The present study was designed to determine the efficacy of administration of PMNs or o...

journal_title：Pediatric research

authors： Santos JI,Shigeoka AO,Hill HR

更新日期：1980-12-01 00:00:00

abstract：:It is customary to estimate the uteroplacental function in singletons by defining appropriateness of birth weight by gestational age. Such a measure, however, is not available for the entire multiple pregnancy set. We evaluate a new index, total triplet birth weight, expressed as multiples of the median (MOM) birth we...

journal_title：Pediatric research

authors： Blickstein I,Salihu HM,Keith LG,Alexander GR

更新日期：2006-04-01 00:00:00

abstract：:There is great interest in the regenerative potential of the neural stem cells and progenitors that populate the germinal zones of the immature brain. Studies using animal models of pediatric brain injuries have provided a clearer understanding of the responses of these progenitors to injury. In this review, we have c...

journal_title：Pediatric research

authors： Niimi Y,Levison SW

更新日期：2018-01-01 00:00:00

abstract：:Labeled choline incorporation into adult rat lung alveolar epithelial cells and adult rat lung fibroblasts in monolayer culture was determined after incubation with insulin (Ins) 10 micrograms/ml, Dexamethasone (Dex) 10(-6)M, or no drug (ND). Incubation periods were 1, 3, 4, and 5 hours. The lecithin (phosphatidyl cho...

journal_title：Pediatric research

authors： Sharp MJ,Borer RC Jr,Vadnay L,Douglas WH

更新日期：1980-07-01 00:00:00

abstract：BACKGROUND:Phytosterols in soybean oil (SO) lipids likely contribute to parenteral nutrition-associated liver disease (PNALD) in infants. No characterization of phytosterol metabolism has been done in infants receiving SO lipids. METHODS:In a prospective cohort study, 45 neonates (36 SO lipid vs. 9 control) underwent ...

journal_title：Pediatric research

authors： Nghiem-Rao TH,Tunc I,Mavis AM,Cao Y,Polzin EM,Firary MF,Wang X,Simpson PM,Patel SB

更新日期：2015-08-01 00:00:00

abstract：:Plasma aldosterone (A), corticosterone (B), deoxycorticosterone (DOC), progesterone (P), 17-hydroxyprogesterone (17-OHP), cortisol (F), and cortisone (E) were measured simultaneously by specific radioimmunoassays in small plasma samples obtained from 174 normal infants and children between 2 hr and 15 yr of age. The s...

journal_title：Pediatric research

authors： Sippell WG,Dörr HG,Bidlingmaier F,Knorr D

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:Sepsis is an important cause of neonatal morbidity and mortality worldwide. Diagnosis and treatment of neonatal sepsis relies on clinical judgment and interpretation of nonspecific laboratory tests. In a prospective cohort, we measured inflammatory cytokines as a potential biomarker for neonatal sepsis. MET...

journal_title：Pediatric research

authors： Ye Q,Du LZ,Shao WX,Shang SQ

更新日期：2017-04-01 00:00:00

abstract：:Studies using stable isotopically labeled glucose and palmitate as precursors of pulmonary surfactant synthesis have demonstrated slow surfactant turnover in premature infants with respiratory distress syndrome (RDS). However, only limited data about surfactant turnover are available for term infants. Because acetate ...

journal_title：Pediatric research

authors： Bohlin K,Merchak A,Spence K,Patterson BW,Hamvas A

更新日期：2003-08-01 00:00:00

abstract：:The microbiome, of which the bacterial component alone (microbiota), is estimated to include 10 times more cells than human cells of the body, blooms immediately after birth and evolves in composition and complexity throughout childhood. The gut microbiome has a profound impact on gastrointestinal tract development, m...

journal_title：Pediatric research

authors： Unger S,Stintzi A,Shah P,Mack D,O'Connor DL

更新日期：2015-01-01 00:00:00

abstract：:We investigated early postnatal changes of the mesenteric circulation and its relationship to the systemic circulation in two groups of newborn infants. Group I (n = 10) was studied before the first feeding at 1 h and preprandially at 6 and 24 h. Group II (n = 10) was studied before the first feeding at 2 h of age and...

journal_title：Pediatric research

authors： Martinussen M,Brubakk AM,Linker DT,Vik T,Yao AC

更新日期：1994-09-01 00:00:00

abstract：:Conversion of adenosine to inosine is decreased in adenosine deaminase (ADA)-deficient fibroblasts at all concentrations of adenosine tested. Adenosine is not differentially toxic to ADA-deficient fibroblasts except at very high (5 X 10(-4) -1 X 10(-3) M) adenosine levels. Conversion of [14C] adenosine to GTP is not d...

journal_title：Pediatric research

authors： Benke PJ,Dittmar D

更新日期：1976-07-01 00:00:00

abstract：:Extracellular glutathione peroxidase (E-GPx) is a selenoenzyme that reduces hydrogen peroxide and organic peroxides. All plasma glutathione peroxidase (GPx) activity in humans is attributable to E-GPx. The gastrointestinal (GI) tract also synthesizes and secretes E-GPx into the extracellular milieu. Endogenously gener...

journal_title：Pediatric research

authors： Tham DM,Whitin JC,Cohen HJ

更新日期：2002-05-01 00:00:00

abstract：:Recent data suggest that umbilical venous perfusion of the fetal liver has an important influence on fetal growth and postnatal liver function, and that maternal factors in late pregnancy modify this circulation. In a longitudinal study of 160 low-risk pregnancies, we determined how umbilical and portal venous blood f...

journal_title：Pediatric research

authors： Kessler J,Rasmussen S,Godfrey K,Hanson M,Kiserud T

更新日期：2008-03-01 00:00:00