Developmental regulation of the sarcoplasmic reticulum calcium pump in the rabbit heart.

abstract：:BackgroundBeing aware of the impact of low birth weight on late-onset hypertension, our aim was to describe systolic blood pressure (sBP) and renal function in 3-5-year-old preterm-born children and to determine which perinatal factors or childhood factors were associated with an altered renal function at 5 years in t...

journal_title：Pediatric research

authors： Vieux R,Gerard M,Roussel A,Sow A,Gatin A,Guillemin F,Hascoet JM

更新日期：2017-12-01 00:00:00

abstract：:Fifty patients with haemophilia B, belonging to 29 kindreds, were investigated with a highly sensitive immunoradiometric assay based on a homologous antibody to factor IX. The assay measures factor IX antigen (f.IX:Ag) in plasma down to 0.025 U/dl. Seventeen of 18 investigated patients with severe haemophilia B had ve...

journal_title：Pediatric research

authors： Ljung R,Holmberg L

更新日期：1982-03-01 00:00:00

abstract：:Cancer stem cells (CSC) are recently proposed to be the cancer initiating cells responsible for tumorigenesis and contribute to cancer resistance. Advances have been made in identifying and enriching CSC in leukemia and several solid tumors, including breast, brain and lung cancers. These studies suggest that, like no...

journal_title：Pediatric research

authors： Guo W,Lasky JL 3rd,Wu H

更新日期：2006-04-01 00:00:00

abstract：:Maternal smoking doubles the risk of delivering a low birth weight infant. The purpose of this study was to analyze differential gene expression in umbilical cord tissue as a function of maternal smoking, with an emphasis on growth-related genes. We recruited 15 pregnant smokers and 15 women who never smoked during pr...

journal_title：Pediatric research

authors： Hussain N,Krueger W,Covault J,Walsh S,Kranzler HR,Oncken C

更新日期：2008-08-01 00:00:00

abstract：:We used quin2, a high affinity fluorescent calcium indicator to measure free cytosolic Ca++ in neutrophils isolated from fresh heparinized blood of 13 cystic fibrosis (CF) patients (age range 6-32 yr) and 11 healthy individuals (age range 25-41 yr) as controls. The mean value of free cytosolic Ca++ for CF patients was...

journal_title：Pediatric research

authors： Suter S,Lew PD,Ballaman J,Waldvogel FA

更新日期：1985-04-01 00:00:00

abstract：:The aim of this study was to produce a neonatal piglet model which, avoiding vessel ligation, exposed the whole animal to hypoxia and produced dose-dependent clinical encephalopathy and neuropathologic damage similar to that seen after birth asphyxia. Twenty-three piglets were halothane-anesthetized. Hypoxia was induc...

journal_title：Pediatric research

authors： Thoresen M,Haaland K,Løberg EM,Whitelaw A,Apricena F,Hankø E,Steen PA

更新日期：1996-11-01 00:00:00

abstract：:Adenylate cyclase activity was measured in membrane preparations of cultured fibroblasts from controls and patients with cystic fibrosis. Enzyme activity increased as the transition from exponential growth to confluence occurred; sodium fluoride-stimulated activity more markedly displayed this relationship than basal ...

journal_title：Pediatric research

authors： Wright RK,Buehler BA,Schott SN,Rennert OM

更新日期：1978-08-01 00:00:00

abstract：:Thrombocytopenia in the first days of life, in association with evidence of reduced megakaryocytopoiesis and platelet production at birth, is common in sick preterm babies. Thrombopoietin (Tpo) is the major regulator of platelet production in adults. However, these babies have low Tpo levels at birth, suggesting that ...

journal_title：Pediatric research

authors： Watts TL,Murray NA,Roberts IA

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:The aim of the study was to describe and contrast the brain development and outcome among very preterm infants that were and were not exposed to surgery requiring general anesthesia prior to term equivalent age (TEA). METHODS:Preterm infants born ≤30 weeks' gestation who did (n = 25) and did not (n = 59) ha...

journal_title：Pediatric research

authors： Walsh BH,Paul RA,Inder TE,Shimony JS,Smyser CD,Rogers CE

更新日期：2020-06-23 00:00:00

abstract：BACKGROUND:Secondhand smoke (SHS) exposure at home and fetal SHS exposure during pregnancy are a major cause of disease among children. The aim of this study is quantifying the burden of disease due to SHS exposure in children and in pregnancy in 2006-2017 for the 28 European Union (EU) countries. METHODS:Exposure to ...

journal_title：Pediatric research

authors： Carreras G,Lachi A,Cortini B,Gallus S,López MJ,López-Nicolás Á,Lugo A,Pastor MT,Soriano JB,Fernandez E,Gorini G,TackSHS Project Investigators.

更新日期：2020-11-04 00:00:00

abstract：:We have previously demonstrated that vagal phase-response curves (PRC), which characterize the effects of critically timed, brief vagal stimuli on sinus node automaticity, exhibit a fundamentally different shape in the canine newborn than in the adult. In this study we analyzed the changes in sinus cycle length in res...

journal_title：Pediatric research

authors： Pickoff AS,Rios R,Stolfi A,Wang SN

更新日期：1994-01-01 00:00:00

abstract：:Carlo Agostoni, MD, and Kwang Sik Kim, MD, are the Guest Editors for this annual review issue on Nutrition and the Microbiome. Dr Agostoni is a Professor of Pediatrics at the Department of Clinical Sciences and Community Health, University of Milan, within the Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, ...

journal_title：Pediatric research

authors： Agostoni C,Kim KS

更新日期：2015-01-01 00:00:00

abstract：:The present study examined the extent to which abundance of the prolactin receptor (PRLR) and a range of primary mitochondrial proteins are influenced by either maternal nutrition and/or fetal number in adipose tissue. Pregnant sheep were control fed [consuming 100% of total metabolizable energy (ME) requirements (tak...

journal_title：Pediatric research

authors： Budge H,Dandrea J,Mostyn A,Evens Y,Watkins R,Sullivan C,Ingleton P,Stephenson T,Symonds ME

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Deficiencies in phagocytosis may contribute to the increased susceptibility of infants to early life infections. Data on phagocytosis of the major neonatal pathogens Staphylococcus epidermidis (SE), Staphylococcus aureus (SA), and Escherichia coli (EC) by preterm infant leukocytes are inconsistent. METHODS:...

journal_title：Pediatric research

authors： Prosser A,Hibbert J,Strunk T,Kok CH,Simmer K,Richmond P,Burgner D,Currie A

更新日期：2013-11-01 00:00:00

abstract：:Long-term parenteral nutrition (TPN) in children is associated with sustained hyperinsulinemia due to a high nutriment infusion flow 12 h/24 h, with plausible lipotoxicity secondary to repeated lipid infusions and with changes in incretin hormone release. The aim of this study was to test whether long-term TPN can lea...

journal_title：Pediatric research

authors： Beltrand J,Colomb V,Marinier E,Daubrosse C,Alison M,Burcelin R,Cani PD,Chevenne D,Marchal CL

更新日期：2007-11-01 00:00:00

abstract：:Altered pulmonary vascular resistance might be a factor for delayed closure of the ductus arteriosus (DA) in preterm infants. Angiotensin II plays a central role in the elevation of pulmonary vascular resistance. Angiotensin II exerts its vasoconstrictor effect on the angiotensin II type 1 receptor (AT1R). Homozygous ...

journal_title：Pediatric research

authors： Treszl A,Szabo M,Dunai G,Nobilis A,Kocsis I,Machay T,Tulassay T,Vasarhelyi B

更新日期：2003-11-01 00:00:00

abstract：:Early detection of developmental delay and childhood disorders are important for early intervention. This study aimed to describe the distribution of responses in a large population-based survey, identify cutoff points for the parent concern checklist (PCC) suitable for the Chinese language and culture, and explore ho...

journal_title：Pediatric research

authors： Lung FW,Shu BC,Chiang TL,Lin SJ

更新日期：2010-02-01 00:00:00

abstract：INTRODUCTION:Current advances in neonatology have improved survival among preterm and low-birth-weight infants. However, the risk of neonatal death in preterm infants is much greater than in full-term neonates and is frequently associated with infections. METHODS:Little is known about the immune status of preterm neon...

journal_title：Pediatric research

authors： Correa-Rocha R,Pérez A,Lorente R,Ferrando-Martínez S,Leal M,Gurbindo D,Muñoz-Fernández MÁ

更新日期：2012-05-01 00:00:00

abstract：:To evaluate the response of the small intestinal mucosa to Saccharomyces boulardii (S.b.), a yeast widely used in some countries as an adjuvant drug with oral antimicrobial therapy, seven healthy adult volunteers were treated with high doses of lyophilized S.b. (250 mg four times per day) for 2 wk. A peroral jejunal s...

journal_title：Pediatric research

authors： Buts JP,Bernasconi P,Van Craynest MP,Maldague P,De Meyer R

更新日期：1986-02-01 00:00:00

abstract：:Very young children with organic brain damage, intractable seizures, and developmental retardation are at particular risk of developing fatal hepatic dysfunction coincident with valproate therapy, especially if the children are also receiving other anticonvulsant drugs. The mechanism of valproate-associated hepatic fa...

journal_title：Pediatric research

authors： Thurston JH,Hauhart RE

更新日期：1992-04-01 00:00:00

abstract：:Plasma amino acid levels in newborn babies are often measured as part of a screening for inherited metabolic disease, or less commonly as part of a nutritional assessment. We have examined certain factors which affect the levels as measured in low birth weight babies during the first 3 wk of life. As in other studies,...

journal_title：Pediatric research

authors： Scott PH,Berger HM,Wharton BA

更新日期：1985-05-01 00:00:00

abstract：:Thoracoabdominal asynchrony (TAA) and chest wall distortion (CWD) are commonly seen in preterm infants secondary to a highly compliant rib cage and poor compensation of distorting forces by inspiratory rib cage muscles. Continuous positive airway pressure (CPAP) reduces TAA and CWD by stenting the chest wall. We hypot...

journal_title：Pediatric research

authors： Musante G,Schulze A,Gerhardt T,Everett R,Claure N,Schaller P,Bancalari E

更新日期：2001-02-01 00:00:00

abstract：:We analyzed by means of immunoblot technique the patterns of antibodies binding to polypeptides of Borrelia burgdorferi B31 in the sera of 21 children with different stages of Lyme disease. All sera but one recognized the flagellar protein 41 kD and all but two the 83-kD protein. The number of proteins recognized rose...

journal_title：Pediatric research

authors： Nadal D,Taverna C,Hitzig WH

更新日期：1989-10-01 00:00:00

abstract：:Previous studies in adults have shown that chronic pulmonary hypertension is associated with decreased endothelial nitric oxide synthase (eNOS) expression in pulmonary arteries. However, the role of decreased eNOS expression in persistent pulmonary hypertension of the newborn (PPHN) is unknown. We investigated the hyp...

journal_title：Pediatric research

authors： Villanueva ME,Zaher FM,Svinarich DM,Konduri GG

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:For the second aim of the Kellogg Foundation grant, this double-blind RCT investigated the impact of plasma vitamin D metabolite 25-hydroxyvitamin D (25(OH)D) on plasma immune-mediators during pregnancy. We hypothesized that higher 25(OH)D concentrations would associate with reduced pro-inflammatory and incr...

journal_title：Pediatric research

authors： Khatiwada A,Wolf BJ,Mulligan JK,Shary JR,Hewison M,Baatz JE,Newton DA,Hawrylowicz C,Hollis BW,Wagner CL

更新日期：2020-04-20 00:00:00

abstract：:Allergies are increasing, and despite deeper insights into the immunologic basis of these diseases, preventive measures are not yet efficient. As the induction of allergic diseases is often triggered in early childhood, perinatal or prenatal preventive strategies would be beneficial. We investigated the transfer of in...

journal_title：Pediatric research

authors： Szépfalusi Z,Loibichler C,Pichler J,Reisenberger K,Ebner C,Urbanek R

更新日期：2000-09-01 00:00:00

abstract：:The short-term (0-48 h) effects of maternal betamethasone administration on computerized fetal heart rate (FHR) parameters were studied in 36 pregnancies at increased risk for preterm delivery. FHR was recorded for 90 min immediately before the start of betamethasone treatment and again at 6-h intervals during the nex...

journal_title：Pediatric research

authors： Lunshof MS,Boer K,Wolf H,Koppen S,Velderman JK,Mulder EJ

更新日期：2005-04-01 00:00:00

abstract：INTRODUCTION:Data regarding neonatal arterial ischemic stroke (NAIS) topography are still sparse and inaccurate. Despite the importance of locating NAIS to predict the long-term outcome of neonates, a map of arterial territories is not yet available. Our aim was therefore to generate the first three-dimensional map of ...

journal_title：Pediatric research

authors： Núñez C,Arca G,Agut T,Stephan-Otto C,García-Alix A

更新日期：2020-06-01 00:00:00

abstract：:Pediatric research may be entering a period of failure to thrive. This is despite impressive scientific achievements, significant financial benefits, intriguing unanswered questions and a rewarding life for the pediatric researcher. Many of the difficulties are financial and situational, including small departments an...

journal_title：Pediatric research

authors： Stiehm ER

更新日期：1985-06-01 00:00:00

abstract：:Increased expression of CD38 on CD8(+) T cells is associated with activation of the immune system, progression of HIV disease, and death in adults. The prognostic significance of these cells in HIV-infected children, where the picture is complicated by age-related differences in CD38 expression, remains controversial....

journal_title：Pediatric research

authors： Sherman GG,Scott LE,Galpin JS,Kuhn L,Tiemessen CT,Simmank K,Meddows-Taylor S,Meyers TM

更新日期：2002-06-01 00:00:00