Estimation of Prevalence of Meibomian Gland Dysfunction in Japan.

Abstract:

PURPOSE:To estimate the prevalence of meibomian gland dysfunction (MGD) in the Japanese population using new diagnostic criteria, including lid margin abnormalities and signs of occlusion of the meibomian gland orifices as essential signs. METHODS:The participants were consecutive patients scheduled for cataract surgery at Inouye Eye Hospital. All participants were aged 50 years or older. The participants completed a symptoms questionnaire and underwent a comprehensive slit-lamp examination. MGD was diagnosed when both of the following 2 factors were positive: lid margin abnormalities and signs of occlusion of the meibomian gland orifices. RESULTS:The study included 510 participants (205 men, 305 women) of mean age 71.1 ± 8.5 (range 50-93) years. The prevalence rates of symptomatic MGD and total (symptomatic + asymptomatic) MGD were 18.0% and 47.5%, respectively. The prevalence of total MGD increased significantly with increasing patient age (P < 0.0001). The ratio of men to women and the prevalence of systemic disease did not differ between participants who were positive or negative for MGD. For the total MGD group, slit-lamp findings (lid margin abnormality, shift of the mucocutaneous junction, telangiectasia, and plugging) were more frequent; tear film breakup time was shorter; and the meiboscore was higher than in participants without MGD. CONCLUSIONS:The prevalence of MGD is high in the Japanese population aged 50 years or older.

journal_name

Cornea

journal_title

Cornea

authors

Amano S,Inoue K

doi

10.1097/ICO.0000000000001208

subject

Has Abstract

pub_date

2017-06-01 00:00:00

pages

684-688

issue

6

eissn

0277-3740

issn

1536-4798

journal_volume

36

pub_type

杂志文章

相关文献

CORNEA文献大全
  • Influence of Pilocarpine and Timolol on Human Meibomian Gland Epithelial Cells.

    abstract:PURPOSE:Investigators have discovered that topical antiglaucoma drugs may induce meibomian gland dysfunction. This response may contribute to the dry eye disease commonly found in patients with glaucoma taking such medications. We hypothesize that drug action involves a direct effect on human meibomian gland epithelial...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001181

    authors: Zhang Y,Kam WR,Liu Y,Chen X,Sullivan DA

    更新日期:2017-06-01 00:00:00

  • Conjunctival resection with and without amniotic membrane graft for the treatment of superior limbic keratoconjunctivitis.

    abstract:PURPOSE:To compare the efficacy of conjunctival resection versus conjunctival resection with amniotic membrane graft (AMG) in patients with superior limbic keratoconjunctivitis not responsive to medical therapies. METHODS:In a retrospective and comparative study, 16 eyes of 9 patients with long-lasting superior limbic...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181d1d1cc

    authors: Gris O,Plazas A,Lerma E,Güell JL,Pelegrín L,Elíes D

    更新日期:2010-09-01 00:00:00

  • Corneal nerve structure and function after long-term wear of fluid-filled scleral lens.

    abstract:PURPOSE:The aim of this study was to determine whether long-term wear of a fluid-filled scleral lens alters basal tear production, corneal sensation, corneal nerve density, and corneal nerve morphology in 2 disease categories. METHODS:Patients recruited from the Prosthetic Replacement of the Ocular Surface Ecosystem (...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000381

    authors: Wang Y,Kornberg DL,St Clair RM,Lee M,Muhic I,Ciralsky JB,Alzaga Fernandez A,Sood P,Sippel KC,Rosenblatt MI

    更新日期:2015-04-01 00:00:00

  • The effect of subconjunctival suramin on corneal neovascularization in rabbits.

    abstract:PURPOSE:To evaluate the effect of subconjunctival injection of suramin on corneal neovascularization in rabbits. METHODS:Corneal neovascularization was induced by silk suturing of the corneal stroma in 40 eyes of 40 male New Zealand white rabbits. Five days after suture placement, all rabbits were randomly divided int...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3181ae91e3

    authors: Lee HS,Chung SK

    更新日期:2010-01-01 00:00:00

  • Fungal Keratitis Caused by Exserohilum, An Emerging Pathogen.

    abstract:PURPOSE:To determine the epidemiology, risk factors, clinical features, and prognosis of fungal keratitis caused by Exserohilum. METHODS:All culture-proven cases of keratomycosis caused by Exserohilum presented from January 2012 to December 2014 were retrospectively analyzed using a computerized database. RESULTS:Amo...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000774

    authors: Rathi H,Venugopal A,Rameshkumar G,Ramakrishnan R,Meenakshi R

    更新日期:2016-05-01 00:00:00

  • Cyclosporine A Downregulates MMP-3 and MMP-13 Expression in Cultured Pterygium Fibroblasts.

    abstract:PURPOSE:To investigate the regulation of matrix metalloproteinase (MMP)-3 and MMP-13 expression over time and in the presence of cyclosporine A (CsA) in primary cultured human pterygium fibroblasts. We also examined the effects of CsA on cultured human pterygium fibroblasts. METHODS:Primary cultured human pterygium fi...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000477

    authors: Kim YH,Jung JC,Jung SY,Kim YI,Lee KW,Park YJ

    更新日期:2015-09-01 00:00:00

  • Treatment of presbyopia with conductive keratoplasty: six-month results of the 1-year United States FDA clinical trial.

    abstract:PURPOSE:To provide 6-month results of a 1-year clinical trial evaluating conductive keratoplasty (CK) for the treatment of presbyopic symptoms in emmetropic and hyperopic eyes. METHODS:A total of 143 patients with presbyopic symptoms were enrolled in this 1-year United States FDA clinical trial and treated to improve ...

    journal_title:Cornea

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1097/01.ico.0000126321.13143.a0

    authors: McDonald MB,Durrie D,Asbell P,Maloney R,Nichamin L

    更新日期:2004-10-01 00:00:00

  • Iris cavernous hemangioma associated with multiple cavernous hemangiomas in the kidney, brain, and skin.

    abstract:PURPOSE:To document the relationship of iris cavernous hemangiomas with multiorgan hemangiomas in a child. METHODS:A 7-year-old girl with kidney hemangiomas, brain hemangiomas, and skin hemangiomas developed blurred vision and darkening of the right iris. She had undergone 6 previous brain surgeries and multiple revis...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3180303b46

    authors: Thangappan A,Shields CL,Dinowitz M,Shields JA

    更新日期:2007-05-01 00:00:00

  • Safety of Intracameral Injection of Minimal Bactericidal Concentration of Povidone Iodine on the Corneal Endothelium in a Rabbit Model.

    abstract:PURPOSE:To investigate the safety of intracameral injection of minimum bactericidal concentration (MBC) of povidone iodine (PI) on the corneal endothelium in a rabbit model as a proposed method of prophylaxis against postoperative endophthalmitis. METHODS:We included 32 New Zealand white rabbits in the study. Twenty-f...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000682

    authors: ElKitkat RS,Ebeid WM,Habib EK,Shoukry Y

    更新日期:2016-01-01 00:00:00

  • Amniotic membrane transplantation with anterior stromal micropuncture for treatment of painful bullous keratopathy in eyes with poor visual potential.

    abstract:PURPOSE:To report the use of anterior stromal micropuncture and amniotic membrane transplantation in the management of painful bullous keratopathy in patients with poor visual potential. METHODS:Interventional case series. A retrospective review was performed to identify all patients who were treated by one of us (A.J...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000244876.92879.c1

    authors: Sonmez B,Kim BT,Aldave AJ

    更新日期:2007-02-01 00:00:00

  • Successful treatment of microsporidial keratoconjunctivitis with topical fumagillin in a patient with AIDS.

    abstract::There recently have been several reports of microsporidial keratoconjunctivitis caused by the organism Encephalitozoon hellem. However, treatment of this infection has been largely ineffective. We report a case of a 35-year-old Hispanic woman with AIDS and E. hellem keratoconjunctivitis confirmed with light, electron,...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199305000-00013

    authors: Rosberger DF,Serdarevic ON,Erlandson RA,Bryan RT,Schwartz DA,Visvesvara GS,Keenan PC

    更新日期:1993-05-01 00:00:00

  • Topical anesthetic abuse ring keratitis: report of four cases.

    abstract:PURPOSE:We present the clinicopathologic correlations of two case and two other clinical cases of topical anesthetic abuse keratopathy that were originally diagnosed as Acanthamoeba keratitis because of ring keratitis presentation and characteristic history. METHODS:Four patients who were referred to us with suspected...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:

    authors: Varga JH,Rubinfeld RS,Wolf TC,Stutzman RD,Peele KA,Clifford WS,Madigan W

    更新日期:1997-07-01 00:00:00

  • Descemet Membrane Endothelial Keratoplasty After Failed Penetrating Keratoplasty.

    abstract:PURPOSE:To demonstrate the feasibility of Descemet membrane endothelial keratoplasty (DMEK) performed after previous penetrating keratoplasty (PK) failure and to describe primary outcomes. METHODS:Twenty-eight eyes of 28 patients who underwent DMEK after primary PK failure between January 2013 and November 2017 were i...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001834

    authors: Pierné K,Panthier C,Courtin R,Mazharian A,Souedan V,Gatinel D,Saad A

    更新日期:2019-03-01 00:00:00

  • In vivo biomechanical changes after corneal collagen cross-linking for keratoconus and corneal ectasia: 1-year analysis of a randomized, controlled, clinical trial.

    abstract:PURPOSE:To investigate the in vivo, corneal, biomechanical changes after corneal collagen cross-linking (CXL) using the Ocular Response Analyzer (ORA) in patients with keratoconus and post-laser in situ keratomileusis (LASIK) ectasia. METHODS:Single-center, prospective, randomized, controlled, clinical trial. After CX...

    journal_title:Cornea

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/ICO.0b013e31821eea66

    authors: Greenstein SA,Fry KL,Hersh PS

    更新日期:2012-01-01 00:00:00

  • Inhibitory effects of tranilast on the proliferation and functions of human pterygium-derived fibroblasts.

    abstract:PURPOSE:We studied the possibility that tranilast, an antiallergic and antiproliferative drug, may be beneficial for the treatment of pterygium. METHODS:Pterygium-derived cells were identified by immunohistochemical methods. Growth rate of pterygium-derived cells was determined by using a hemocytometer. Chemotaxis was...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200005000-00021

    authors: Isaji M,Kikuchi S,Miyata H,Ajisawa Y,Araki-Inazawa K,Tsukamoto Y,Amano Y

    更新日期:2000-05-01 00:00:00

  • Elevated immunoglobulin to tissue KLK11 in patients with Sjögren syndrome.

    abstract:PURPOSE:We have previously reported that mouse kallikrein (KLK) 22 in the lacrimal and salivary glands is an autoantigen that can induce primary Sjogren syndrome (SS) in rats. In this study, we determine whether the production of antibodies against tissue KLK is specific for SS and whether the antibody can be used as a...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31826a1e2e

    authors: El Annan J,Jiang G,Wang D,Zhou J,Foulks GN,Shao H

    更新日期:2013-05-01 00:00:00

  • Intracorneal ring segment explantation after intracorneal ring segment implantation combined with same-day corneal collagen crosslinking in keratoconus.

    abstract:PURPOSE:To report the outcome and the reversibility of refractive outcomes after intrastromal corneal ring segment (ICRS) explantation in patients with keratoconus treated with ICRS implantation and same-day collagen crosslinking (CXL). METHODS:This is a retrospective review of ICRS explantation in 3 eyes of 3 patient...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e3182a738ba

    authors: Yeung SN,Lichtinger A,Ku JY,Kim P,Low SA,Rootman DS

    更新日期:2013-12-01 00:00:00

  • Corneal Fine Needle Diathermy With Adjuvant Bevacizumab to Treat Corneal Neovascularization in Children.

    abstract:PURPOSE:To report the outcomes of corneal fine needle diathermy (FND) with adjuvant intrastromal and subconjunctival bevacizumab injection for corneal neovascularization (CN) in children. METHODS:Medical records of all children who had undergone FND with adjuvant bevacizumab injection were reviewed retrospectively. Tr...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000000419

    authors: Elbaz U,Mireskandari K,Shen C,Ali A

    更新日期:2015-07-01 00:00:00

  • Effects of corneal cross-linking on contrast sensitivity, visual acuity, and corneal topography in patients with keratoconus.

    abstract:PURPOSE:To assess the effects of corneal collagen cross-linking (CXL) on contrast sensitivity (CS), visual acuity, and corneal topography investigating possible predictors of efficacy. METHODS:Sixty-eight eyes of 34 patients with progressive keratoconus were enrolled in this prospective study. CXL was performed in one...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31826672e2

    authors: Lamy R,Netto CF,Reis RG,Procopio B,Porco TC,Stewart JM,Dantas AM,Moraes HV Jr

    更新日期:2013-05-01 00:00:00

  • Use of impression cytology to demonstrate a retrovirus in AIDS patients with cytomegalovirus retinitis.

    abstract::Utilizing transmission electron microscopy, the authors describe results obtained from cellulose acetate impressions of the bulbar conjunctiva in acquired immunodeficiency syndrome patients with cytomegalovirus (CMV) retinitis. Particles consistent with a retrovirus were isolated, but no CMV particles were demonstrate...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199111000-00008

    authors: Pastor SA,Shuster AR,Miller MM,Lam KW

    更新日期:1991-11-01 00:00:00

  • Correlation Between Corneal Biomechanical Indices and the Severity of Keratoconus.

    abstract:PURPOSE:To investigate the correlations between the biomechanical indices determined in Scheimpflug-based corneal biomechanical assessments and the severity of keratoconus (KC) based on corneal tomographic assessments in patients with different stages of KC. METHODS:Fifty-three patients who presented with clinical KC ...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002129

    authors: Koh S,Inoue R,Ambrósio R Jr,Maeda N,Miki A,Nishida K

    更新日期:2020-02-01 00:00:00

  • Absorption of topical moxifloxacin ophthalmic solution into human aqueous humor.

    abstract:PURPOSE:To investigate the absorption of moxifloxacin into human aqueous humor after administration of moxifloxacin hydrochloride ophthalmic solution, 0.5% as base. METHODS:Cataract patients were randomly allocated to receive 1 drop every 15 minutes for 4 doses before surgery (group 1) or 1 drop 4 times per day on the...

    journal_title:Cornea

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/01.ico.0000157423.78275.a2

    authors: Katz HR,Masket S,Lane SS,Sall K,Orr SC,Faulkner RD,McCue BA,Dahlin DC

    更新日期:2005-11-01 00:00:00

  • Effect of fourth-generation fluoroquinolones on the healing rate of corneal erosions in an animal model.

    abstract:PURPOSE:To compare the rate of epithelial healing of corneal erosion in an animal model with 2 commercial formulations of fourth-generation fluoroquinolones: 0.3% gatifloxacin and 0.5% moxifloxacin. METHODS:Corneal erosions, 6 mm in diameter, were created in 28 rabbit eyes. The rabbits were randomized to receive topic...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e318041f08e

    authors: Barequet IS,Habot-Wilner Z,Lavinsky F,Ziv H,Belkin M,Rosner M

    更新日期:2007-06-01 00:00:00

  • Herpes simplex virus genome quantification in two patients who developed herpetic epithelial keratitis during treatment with antiglaucoma medications.

    abstract:PURPOSE:We quantitated herpes simplex virus (HSV) DNA in tear film obtained from 2 patients who developed herpetic epithelial keratitis (HEK) during treatment with latanoprost and a beta-blocker. METHODS:The patient in case 1 is a 77-year-old woman with bilateral open-angle glaucoma who had been treated with latanopro...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-200403000-00004

    authors: Deai T,Fukuda M,Hibino T,Higaki S,Hayashi K,Shimomura Y

    更新日期:2004-03-01 00:00:00

  • Fusarium keratitis in Mexico.

    abstract:PURPOSE:To describe the clinical characteristics, diagnosis, treatment, and visual outcome of 61 cases of Fusarium keratitis in Mexico. METHODS:Retrospective, comparative study of 61 patients with clinically and culture-confirmed Fusarium keratitis, who were attended at an eye hospital in Mexico City from 1981 to 2001...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0b013e31819bc2ea

    authors: Pérez-Balbuena AL,Vanzzini-Rosano V,Valadéz-Virgen Jde J,Campos-Möller X

    更新日期:2009-07-01 00:00:00

  • Anterior-Segment Optical Coherence Tomography and Scanning Electron Microscopy to Evaluate Corneal Epithelial Changes in Patients Undergoing Glaucoma Therapy.

    abstract:PURPOSE:To measure corneal epithelial thickness (CET) in patients with glaucoma using anterior-segment optical coherence tomography and to evaluate CET changes in relation to corneal epithelial microvilli analyzed by scanning electron microscopy (SEM). METHODS:Twenty-two eyes (16 patients) being treated with preservat...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000001752

    authors: Cennamo G,Montorio D,Del Prete S,Del Prete A,Cennamo G

    更新日期:2018-12-01 00:00:00

  • Progressive replacement of oral mucosa by conjunctiva in osteo-odonto-keratoprosthesis: preliminary observations.

    abstract:PURPOSE:In a Strampelli osteo-odonto-keratoprosthesis, a patch of oral mucosa is frequently used to cover the ocular surface after implantation of an osteodental lamina into the eye. In many cases, gross modifications in the eye covering become apparent a few years later. The aim of this study was to investigate the hi...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/01.ico.0000170695.98078.42

    authors: Pecorella I,Maurizio T,Antonio C,Giancarlo F

    更新日期:2006-02-01 00:00:00

  • Comparative Evaluation of Central Corneal Thickness in Cross-Linked Keratoconic Eyes.

    abstract:PURPOSE:To compare the central corneal thickness (CCT) measurements measured by using the Pentacam Scheimpflug system with the CCT measured using ultrasound pachymetry (UP) and to compare the compatibility between the methods in normal, keratoconic, and cross-linked keratoconic corneas. METHODS:The study included 50 e...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002339

    authors: Kosekahya P,Koc M,Yalcinsoy KO,Kocabas DO,Toker MI

    更新日期:2020-09-01 00:00:00

  • Alkali Burn Over a LASIK Flap.

    abstract:PURPOSE:To describe the management and outcome of an ocular surface alkali burn in the setting of previous laser in situ keratomileusis (LASIK). METHODS:This is a case report and review of relevant literature. RESULTS:A 25-year-old man with a history of LASIK presented 4 weeks after a sodium hydroxide splash to his l...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/ICO.0000000000002604

    authors: Witsberger EM,Patel SV

    更新日期:2020-12-03 00:00:00

  • The BioMask for treatment of corneal surface irregularities with excimer laser phototherapeutic keratectomy.

    abstract:PURPOSE:To assess the characteristics of BioMask as a potential masking agent for use with the excimer laser. METHOD:We addressed ablation rate, smoothness, ease of use, dioptric shift, treatment of standardized irregular topography, and ability of BioMask to induce dioptric change in vivo. RESULTS:BioMask ablates at...

    journal_title:Cornea

    pub_type: 杂志文章

    doi:10.1097/00003226-199903000-00003

    authors: Stevens SX,Bowyer BL,Sanchez-Thorin JC,Rocha G,Young DA,Rowsey JJ

    更新日期:1999-03-01 00:00:00