Abstract:
:Complex, multicomponent excitatory postsynaptic potentials (EPSPs) of the red nucleus rubrospinal neurons evoked by stimulation of the sensorimotor cortex and associative field of the parietal cortex were studied in acute experiments on pentobarbitalized cats by the intracellular recording technique. Complex cortical EPSPs were recorded in two-thirds of the studied number of neurons. Monosynaptic nature of the first two components of EPSPs evoked by corticofugal impulses propagating at an average velocity of 18.5 ms and 7.5 ms was revealed. Participation of the corticospinal input in the genesis of EPSPs mentioned was revealed by selective activation of corticospinal fibers on the level of medullary pyramids as well as by studying peculiarities of their interaction with effects of cortical stimulation. It was shown that both corticospinal and corticorubral (predominantly slow conducting) neurons participate in the genesis of the first two components of complex EPSPs.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Fanardjian VV,Gorodnov VLdoi
10.1016/0166-4328(88)90089-7subject
Has Abstractpub_date
1988-04-01 00:00:00pages
131-7issue
1-2eissn
0166-4328issn
1872-7549pii
0166-4328(88)90089-7journal_volume
28pub_type
杂志文章abstract::Different methods of inducing experimental brain lesions can result in distinct neuropathological sequelae. This could be of consequence in attempts to establish animal models of recovery of function following stroke, as differences in the progression of experimental lesion pathology may have an impact on the magnitud...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2003.07.006
更新日期:2004-04-02 00:00:00
abstract::Cognitive flexibility (i.e. the ability to adapt goal-directed behaviour in response to changed environmental demands) has repeatedly been shown to depend on the prefrontal cortex (PFC). Recent data from primate studies moreover show that depletion of prefrontal 5-HT impairs reversal learning of visual stimuli [Clarke...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2007.07.017
更新日期:2008-01-10 00:00:00
abstract::Attention to stimuli associated with a rewarding outcome may be mediated by the incentive motivational properties that the stimulus acquires during conditioning. Other theories of attention state that the prediction error (the discrepancy between the expected and the actual outcome) during conditioning guides attentio...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2012.04.009
更新日期:2012-06-15 00:00:00
abstract::A subclass of C-fibres, C-tactile afferents (CTs), have been discovered which respond preferentially to low force/velocity stroking touch, that is typically perceived as pleasant. Molecular genetic visualization of these low-threshold mechanosensitive C-fibres (CLTMs) in mice revealed a denser distribution in dorsal t...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2016.11.046
更新日期:2017-03-01 00:00:00
abstract::The present study examines how rats process object information in relation to other objects as well as to the global shape of an enclosure. Rats were introduced into either a round or a square arena with various arrays of freestanding portable corners (objects) that differed in spacing, orientation, and number. We fou...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2007.09.027
更新日期:2008-03-05 00:00:00
abstract::Deep brain stimulation (DBS) has gained interest as a potential therapy for advanced treatment-resistant dementia. However, possible targets for DBS and the optimal stimulation parameters are not yet clear. Here, we compared the effects of DBS of the CA1 sub-region of the hippocampus, mammillothalamic tract, anterior ...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2015.06.032
更新日期:2015-10-01 00:00:00
abstract::Maternal care is the newborns' first experience of social interaction, which affects their development and social competence throughout life. For the first time, we investigated the involvement of the endocannabinoid system (ECS) in mother-infant interaction in mice. We found that blocking the dam's CB1 receptors (CB1...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2011.10.016
更新日期:2012-01-15 00:00:00
abstract::Previous behavioral studies have manipulated nitric oxide (NO) production either by pharmacological inhibition of its synthetic enzyme, nitric oxide synthase (NOS), or by deletion of the genes that code for NOS. However manipulation of dietary intake of the NO precursor, L-arginine, has been understudied in regard to ...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2011.04.011
更新日期:2011-09-30 00:00:00
abstract::The dopamine (DA) precursor, L-DOPA (500 microg), was injected into living crickets, which were ingested (one each) by adult male Anolis carolinensis. This method of delivery elevated plasma L-DOPA and DA concentrations by approximately 1000-fold. In contrast, plasma epinephrine (Epi) and norepinephrine (NE) were not ...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2004.05.009
更新日期:2005-01-06 00:00:00
abstract::In the hippocampus of freely moving rats, neurons have been recorded that fire predominantly when the animal travels through a particular area while exploring the environment (so-called 'place cells'). This study investigates if the neuronal firing characteristics of such cells are modulated by attention, expectation ...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(02)00422-9
更新日期:2003-06-16 00:00:00
abstract::Early life experience profoundly impacts behavior and cognitive functions in rats. The present study investigated how the presence of conspecifics and/or novel objects, could independently influence individual differences in impulsivity and behavioral flexibility. Twenty-four rats were reared in an isolated condition,...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2017.03.028
更新日期:2017-06-01 00:00:00
abstract::Peripherally and locally administered rotenone (an inhibitor of mitochondrial complex I) has been proposed as a model of Parkinson's disease (PD) as it induces nigrostriatal degeneration associated with alpha-synuclein inclusions. If rotenone-induced symptoms represent a model of PD, than they should be counteracted b...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2003.12.021
更新日期:2004-08-31 00:00:00
abstract::Previous studies showed that the repeated administration with a low dose of reserpine (RES) induces a gradual appearance of motor signs and cognitive deficits compatible with parkinsonism in rodents. Environmental stimulation has neuroprotective effects in animal models of neurodegenerative damage, including acutely i...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2017.04.028
更新日期:2017-06-15 00:00:00
abstract::Different strategies can be used to carry dopamine into the brain such as L-Dopa precursors or galactosilated form of DA (GAL-DA). The aim of this study was to investigate whether GAL-DA would reduce hyperactivity and increase non-selective attention (NSA) in a mouse model of attention deficit hyperactivity disorder (...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2007.10.007
更新日期:2008-03-05 00:00:00
abstract::Serotonin (5-HT) acts as a neurogenic compound in the developing brain; however serotonin altering drugs such as SSRIs are often prescribed to pregnant and lactating mothers. Early agonism of 5-HT receptors could alter the development of serotonergic circuitry, altering neurotransmission and behaviors mediated by 5-HT...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2013.07.043
更新日期:2013-09-15 00:00:00
abstract::We hypothesized that memantine, an anti-dementia drug, may be useful for the treatment of excessive daytime sleepiness. The effect of memantine on excessive sleepiness after 6 h sleep deprivation was studied in comparison with that of methylphenidate, and the involvement of the dopaminergic system in the wakefulness-p...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2009.09.025
更新日期:2010-01-20 00:00:00
abstract::These experiments examined the mnemonic functions of hippocampus and dorsal striatum in Pavlovian aversive conditioning. Rats were trained in a single session by presenting three paired tones and footshocks. Immediately after training, they were given microinjections of D-amphetamine or vehicle into either dorsal hipp...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(02)00402-3
更新日期:2003-06-16 00:00:00
abstract::We describe a stereotaxic technique to transect the optic chiasm in the rat and present illustrative data on the interocular transfer of visual discrimination in chiasm-sectioned and chiasm-plus-forebrain commissure-sectioned animals. Applications of the technique are discussed. ...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(05)80069-5
更新日期:1991-05-15 00:00:00
abstract:BACKGROUND:The applicability of various neurological scores has not been sufficiently characterized in the anterior injection model of subarachnoid hemorrhage (SAH). Therefore this study was performed to evaluate different behavioral tests for quantifying disease severity. METHODS:Different volumes of autologous blood...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2017.02.004
更新日期:2017-04-14 00:00:00
abstract::Sensory-motor development begins early during embryogenesis and is influenced by sensory experience. Little is known about the prenatal factors that influence the development of motor coordination. Here we investigated whether and to what extent prenatal light experience can influence the development of motor coordina...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2017.03.039
更新日期:2017-06-01 00:00:00
abstract:INTRODUCTION:Several human studies have reported that coffee consumption improves cognitive performance. In the present study, we investigated whether instant decaffeinated coffee also ameliorates cognitive performance and attenuates the detrimental effects of scopolamine on memory. METHODS:Memory performance was eval...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2013.02.003
更新日期:2013-05-15 00:00:00
abstract::Gangliosides are compounds that are abundant throughout the CNS, participating actively in neuroplasticity. We previously described that exogenous GM1 ganglioside pretreatment enhances the rewarding properties of cocaine, evidenced by a lower number of sessions and/or dosage necessary to induce conditioned place prefe...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2014.10.013
更新日期:2015-02-01 00:00:00
abstract::Childhood and adolescent adversity are associated with a wide range of psychiatric disorders, including an increased risk for substance abuse. Despite this, the mechanisms underlying the ability of chronic stress during adolescence to alter reward signaling remains largely unexplored. Understanding how adolescent stre...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2018.10.007
更新日期:2019-02-01 00:00:00
abstract::The present study was undertaken to test the hypothesis that dysregulation of the amygdala contributes to the exaggerated autonomic response to stress in an animal model of essential hypertension. Spontaneously hypertensive (SHR) and normotensive Wistar male rats were chronically instrumented and exposed to 20 min of ...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2010.08.036
更新日期:2011-01-20 00:00:00
abstract::Axonal branching patterns of physiologically identified cerebellar nucleus neurones and rubrospinal neurones were investigated in the cat with intra-axonal injection of horseradish peroxidase and 3-dimensional reconstruction on serial sections. Axons of dentate and interpositus neurones projected to the VL nucleus of ...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/0166-4328(88)90076-9
更新日期:1988-04-01 00:00:00
abstract::The nuclear complex of the horizontal limb of the diagonal band and the magnocellular preoptic nucleus, components of the basal forebrain magnocellular system affected in Alzheimer-type dementia, supply centrifugal innervation to the olfactory bulb. The lateral magnocellular preoptic nucleus provides significant GABAe...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(96)89082-6
更新日期:1996-11-01 00:00:00
abstract::A chronic 10-day amphetamine (Amp) protocol was used to induce significant long-term decrements of the striatal [18F]fluoro-L-DOPA influx rate constant (FDOPA Ki) in the vervet monkey. Longitudinal FDOPA-positron emission tomography (PET) assessment in Amp-treated subjects subsequently revealed a gradual recovery of s...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(97)83333-5
更新日期:1997-03-01 00:00:00
abstract::About 99% of the unique genes and almost half of the cells found in the human body come from microbes including bacteria, archaea, fungi, and viruses. Collectively these microorganisms contribute to the microbiome and often reside in the gut. The gut microbiome plays an important role in the body and contributes to di...
journal_title:Behavioural brain research
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.bbr.2019.112196
更新日期:2019-12-30 00:00:00
abstract::The outcome of behavioral interactions between organisms can have significant fitness implications. Therefore, it is of great theoretical and practical importance to understand the mechanisms that modify different agonistic behaviors. Changes in central monoamines, such as serotonin (5-HT), contribute to modifying the...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2013.10.050
更新日期:2014-02-01 00:00:00
abstract::Mesocortical dopamine (DA) terminals in the ventromedial prefrontal cortex (vmPFC) integrate cognitive/emotional processing functions underlying adaptive and appropriate behavioral responding to stressful environmental events. Results from several studies have also shown that stressor-enhanced prefrontal DA activation...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2003.09.035
更新日期:2004-06-04 00:00:00