Apical External Root Resorption and Repair in Orthodontic Tooth Movement: Biological Events.

Abstract:

:Some degree of external root resorption is a frequent, unpredictable, and unavoidable consequence of orthodontic tooth movement mediated by odontoclasts/cementoclasts originating from circulating precursor cells in the periodontal ligament. Its pathogenesis involves mechanical forces initiating complex interactions between signalling pathways activated by various biological agents. Resorption of cementum is regulated by mechanisms similar to those controlling osteoclastogenesis and bone resorption. Following root resorption there is repair by cellular cementum, but factors mediating the transition from resorption to repair are not clear. In this paper we review some of the biological events associated with orthodontically induced external root resorption.

journal_name

Biomed Res Int

authors

Feller L,Khammissa RA,Thomadakis G,Fourie J,Lemmer J

doi

10.1155/2016/4864195

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

4864195

eissn

2314-6133

issn

2314-6141

journal_volume

2016

pub_type

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