Platelet-Rich Plasma Obtained with Different Anticoagulants and Their Effect on Platelet Numbers and Mesenchymal Stromal Cells Behavior In Vitro.

abstract：:The Wnt signalling pathway plays a crucial role in the development of the nervous system. This signalling cascade is initiated upon binding of the secreted Wnt ligand to a member of the family of frizzled receptors. In the present study, we analysed the presence of frizzled-4 in the enteric nervous system of human inf...

journal_title：Stem cells international

authors： Nothelfer K,Obermayr F,Belz N,Reinartz E,Bareiss PM,Bühring HJ,Beschorner R,Just L

更新日期：2016-01-01 00:00:00

abstract：Objective:To investigate the effects of mesenchymal stem cells (MSCs) coated by the extracellular matrix (ECM) on wound healing in diabetic rats. Methods:Mesenchymal stem cells were cocultured with ECM. Cell viabilities were evaluated using MTT assay. The diabetes model was established using both STZ and high-glucose/...

journal_title：Stem cells international

authors： Wang L,Wang F,Zhao L,Yang W,Wan X,Yue C,Mo Z

更新日期：2019-01-28 00:00:00

abstract：Background:Cancer stem cell (CSC) promotes angiogenesis which plays an important role in tumor occurrence, growth, and metastasis. Accurately, quantifying the tumor vasculature can help understanding CSC characteristics and improve cancer diagnosis, therapy planning, and evaluation. The objective of this study is to pr...

journal_title：Stem cells international

authors： Zhang L,Zheng F,Peng Z,Hu Z,Yang Z

更新日期：2018-04-03 00:00:00

abstract：:Vitamin D (Vit D) by means of its biological active form, 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3), has a protective effect on the skeleton by acting on calcium homeostasis and bone formation. Furthermore, Vit D has a direct effect on mesenchymal stem cells (MSCs) in stimulating their osteogenic differentiation. In thi...

journal_title：Stem cells international

authors： Posa F,Di Benedetto A,Cavalcanti-Adam EA,Colaianni G,Porro C,Trotta T,Brunetti G,Lo Muzio L,Grano M,Mori G

更新日期：2018-02-28 00:00:00

abstract：:This study evaluated the efficacy of mesenchymal stem cells (MSCs) from bone marrow of a third-party donor for refractory aGVHD. We report the first experience using MSCs to treat refractory aGVHD in 33 pediatric patients undergoing allogeneic HSCT from Turkey. Totally, 68 doses of bone marrow derived MSCs were infuse...

journal_title：Stem cells international

authors： Erbey F,Atay D,Akcay A,Ovali E,Ozturk G

更新日期：2016-01-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) are one of the main stem cells that have been used for advanced therapies and regenerative medicine. To carry out the translational clinical application of MSCs, their manufacturing and administration in human must be controlled; therefore they should be considered as medicine: stem cell-...

journal_title：Stem cells international

authors： Galvez-Martin P,Sabata R,Verges J,Zugaza JL,Ruiz A,Clares B

更新日期：2016-01-01 00:00:00

abstract：:Coronary revascularization remains the standard treatment for obstructive coronary artery disease and can be accomplished by either percutaneous coronary intervention (PCI) or coronary artery bypass graft surgery. Considerable advances have rendered PCI the most common form of revascularization and improved clinical o...

journal_title：Stem cells international

authors： Simard T,Jung RG,Motazedian P,Di Santo P,Ramirez FD,Russo JJ,Labinaz A,Yousef A,Anantharam B,Pourdjabbar A,Hibbert B

更新日期：2017-01-01 00:00:00

abstract：:Schwann cell (SC) transplantation as a cell-based therapy can enhance peripheral and central nerve repair experimentally, but it is limited by the donor site morbidity for clinical application. We investigated weather respiratory mucosa stem cells (REMSCs), a kind of ectomesenchymal stem cells (EMSCs), isolated from r...

journal_title：Stem cells international

authors： Zhang J,Gao X,Zou H,Liu J,Zhang Z

更新日期：2015-01-01 00:00:00

abstract：:Dental pulp stem cells (DPSCs) are ideal seed cells for the regeneration of dental tissues. However, DPSC senescence restricts its clinical applications. Metformin (Met), a common prescription drug for type 2 diabetes, is thought to influence the aging process. This study is aimed at determining the effects of metform...

journal_title：Stem cells international

authors： Zhang S,Zhang R,Qiao P,Ma X,Lu R,Wang F,Li C,E L,Liu H

更新日期：2021-01-06 00:00:00

abstract：:Designing and providing a scaffold are very important for the cells in tissue engineering. Polybutylene succinate (PBS) has high potential as a scaffold for bone regeneration due to its capacity in cell proliferation and differentiation. Also, stem cells from 3rd molar tooth germs were favoured in this study due to th...

journal_title：Stem cells international

authors： Abay N,Gurel Pekozer G,Ramazanoglu M,Kose GT

更新日期：2016-01-01 00:00:00

abstract：:Fibrosis of the skin and of internal organs, autoimmunity, and vascular inflammation are hallmarks of Systemic Sclerosis (SSc). The injury and activation of endothelial cells, with hyperplasia of the intima and eventual obliteration of the vascular lumen, are early features of SSc. Reduced capillary blood flow coupled...

journal_title：Stem cells international

authors： Nicolosi PA,Tombetti E,Maugeri N,Rovere-Querini P,Brunelli S,Manfredi AA

更新日期：2016-01-01 00:00:00

abstract：:Background and Objectives. Culture expanded multipotential stromal cells (MSCs) have considerable potential for bone regeneration therapy but their wider use is constrained by the lack of simple and predictive assays of functional potency. Extended passaging leads to loss of multipotency but speed of decline depends o...

journal_title：Stem cells international

authors： Churchman SM,Boxall SA,McGonagle D,Jones EA

更新日期：2017-01-01 00:00:00

abstract：:Sepsis, newly defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection, is the most common cause of death in ICUs and one of the principal causes of death worldwide. Although substantial progress has been made in the understanding of fundamental mechanisms of sepsis, translat...

journal_title：Stem cells international

authors： Horák J,Nalos L,Martínková V,Beneš J,Štengl M,Matějovič M

更新日期：2017-01-01 00:00:00

abstract：:Increasing the success rate of rotator cuff healing remains tremendous challenge. Among many approaches, the possibility of activating resident stem cells in situ, without the need to isolate them from biopsies, could represent valuable therapeutic strategy. Along this line, it has been recently demonstrated that lipo...

journal_title：Stem cells international

authors： Randelli P,Menon A,Ragone V,Creo P,Bergante S,Randelli F,De Girolamo L,Alfieri Montrasio U,Banfi G,Cabitza P,Tettamanti G,Anastasia L

更新日期：2016-01-01 00:00:00

abstract：:Human embryonic stem cells (hESCs) are being utilized in diverse areas of studies such as development and disease modeling, cell replacement therapy, or drug toxicity testing because of their potential to be differentiated into any cell type in the body. The directed differentiation of hESCs into hepatocytes could pro...

journal_title：Stem cells international

authors： Varghese DS,Alawathugoda TT,Ansari SA

更新日期：2019-01-22 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2017/3978595.]. ...

journal_title：Stem cells international

authors： Zadroga A,Jezierska-Woźniak K,Czarzasta J,Barczewska M,Wojtkiewicz J,Maksymowicz W

更新日期：2017-01-01 00:00:00

abstract：:We attempted transplantation of adult neural stem cells (ANSCs) inside an autologous venous graft following surgical transsection of nervis cruralis with 30 mm long gap in adult pig. The transplanted cell suspension was a primary culture of neurospheres from adult pig subventricular zone (SVZ) which had been labeled i...

journal_title：Stem cells international

authors： Liard O,Segura S,Sagui E,Nau A,Pascual A,Cambon M,Darlix JL,Fusai T,Moyse E

更新日期：2012-01-01 00:00:00

abstract：:Whether liver epithelial cells contribute to the development of hepatic scarring by undergoing epithelial-to-mesenchymal transition (EMT) is a controversial issue. Herein, we revisit the concept of EMT in cholangiopathies, a group of severe hepatic disorders primarily targeting the bile duct epithelial cell (cholangio...

journal_title：Stem cells international

authors： Fabris L,Brivio S,Cadamuro M,Strazzabosco M

更新日期：2016-01-01 00:00:00

abstract：:Dental Mesenchymal Stem Cells (MSCs), including Dental Pulp Stem Cells (DPSCs), Stem Cells from Human Exfoliated Deciduous teeth (SHED), and Stem Cells From Apical Papilla (SCAP), have been extensively studied using highly sophisticated in vitro and in vivo systems, yielding substantially improved understanding of the...

journal_title：Stem cells international

authors： Bakopoulou A,About I

更新日期：2016-01-01 00:00:00

abstract：:Alopecia is caused by a variety of factors which affect the hair cycle and decrease stem cell activity and hair follicle regeneration capability. This process causes lower self-acceptance, which may result in depression and anxiety. However, an early onset of androgenic alopecia is associated with an increased inciden...

journal_title：Stem cells international

authors： Owczarczyk-Saczonek A,Krajewska-Włodarczyk M,Kruszewska A,Banasiak Ł,Placek W,Maksymowicz W,Wojtkiewicz J

更新日期：2018-08-05 00:00:00

abstract：:Mandibular bone defect reconstruction is an urgent challenge due to the requirements for daily eating and facial aesthetics. Three-dimensional- (3D-) printed titanium (Ti) scaffolds could provide patient-specific implants for bone defects. Appropriate load-bearing properties are also required during bone reconstructio...

journal_title：Stem cells international

authors： Yu L,Wu Y,Liu J,Li B,Ma B,Li Y,Huang Z,He Y,Wang H,Wu Z,Qiu G

更新日期：2018-09-05 00:00:00

abstract：:Purpose. The current study was set out to address the therapeutic efficacy of topically applied mesenchymal stem cells (MSCs) on dry eye syndrome (DES) induced by benzalkonium chloride (BAC) in rats. Methods. Rats were divided into two groups just after establishment of DES. Eye drops containing either bromodeoxyuridi...

journal_title：Stem cells international

authors： Beyazyıldız E,Pınarlı FA,Beyazyıldız O,Hekimoğlu ER,Acar U,Demir MN,Albayrak A,Kaymaz F,Sobacı G,Delibaşı T

更新日期：2014-01-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs), or multipotent mesenchymal stromal cells, are present in almost all organs and tissues, including the amnion. Human amnion-derived mesenchymal stem cell (hAMSC) transplantation has been reported to ameliorate liver fibrosis in animal models. However, the mechanism for the prevention of l...

journal_title：Stem cells international

authors： Fu Q,Ohnishi S,Sakamoto N

更新日期：2018-10-08 00:00:00

abstract：:The use of stem cells as a strategy for tissue repair and regeneration is one of the biomedical research areas that has attracted more interest in the past few years. Despite the classic belief that the central nervous system (CNS) was immutable, now it is well known that cell turnover occurs in the mature CNS. Postna...

journal_title：Stem cells international

authors： Martínez-Herrero S,Larráyoz IM,Ochoa-Callejero L,García-Sanmartín J,Martínez A

更新日期：2012-01-01 00:00:00

abstract：:The cardiopulmonary system is made up of the heart and the lungs, with the core function of one complementing the other. The unimpeded and optimal cycling of blood between these two systems is pivotal to the overall function of the entire human body. Although the function of the cardiopulmonary system appears uncompli...

journal_title：Stem cells international

authors： Fakoya AOJ,Otohinoyi DA,Yusuf J

更新日期：2018-04-29 00:00:00

abstract：:Mesenchymal stem cells (MSCs) are multipotent stem cells characterized by self-renewal, production of clonal cell populations, and multilineage differentiation. They exist in nearly all tissues and play a significant role in tissue repair and regeneration. Additionally, MSCs possess wide immunoregulatory properties vi...

journal_title：Stem cells international

authors： Wang M,Yuan Q,Xie L

更新日期：2018-06-14 00:00:00

abstract：:Hematopoietic stem cell transplantation (HSCT) is one of a range of therapeutic options available to patients suffering from various diseases. HSCT procedure involves important ethical and legal aspects that can occur at every phase of the procedure: the clinical choice of whether to perform the procedure, pretranspla...

journal_title：Stem cells international

authors： Liso A,Neri M,Maglietta F,La Russa R,Turillazzi E

更新日期：2017-01-01 00:00:00

abstract：:An intermediate filament protein, Nestin, is known as a neural stem/progenitor cell marker. It was shown to be required for the survival and self-renewal of neural stem cells according to the phenotypes of Nestin knockout mice. Nestin expression has also been reported in vascular endothelial cells, and we recently rep...

journal_title：Stem cells international

authors： Namiki J,Suzuki S,Masuda T,Ishihama Y,Okano H

更新日期：2012-01-01 00:00:00

abstract：:Calcium phosphate- (CaP-) based composite scaffolds have been used extensively for the bone regeneration in bone tissue engineering. Previously, we developed a biomimetic composite nanofibrous membrane of gelatin/β-tricalcium phosphate (TCP) and confirmed their biological activity in vitro and bone regeneration in viv...

journal_title：Stem cells international

authors： Zhang X,Meng S,Huang Y,Xu M,He Y,Lin H,Han J,Chai Y,Wei Y,Deng X

更新日期：2015-01-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) derived from induced pluripotent stem cells (iPSCs) are a promising cell source for the repair of skeletal disorders. Recently, neural crest cells (NCCs) were reported to be effective for inducing mesenchymal progenitors, which have potential to differentiate into osteochondral lineages. ...

journal_title：Stem cells international

authors： Chijimatsu R,Ikeya M,Yasui Y,Ikeda Y,Ebina K,Moriguchi Y,Shimomura K,Hart DA,Hideki Y,Norimasa N

更新日期：2017-01-01 00:00:00