Contribution of synchronized GABAergic neurons to dopaminergic neuron firing and bursting.

abstract：:Our perception of the positions of objects in our surroundings is surprisingly unaffected by movements of the eyes, head, and body. This suggests that the brain has a mechanism for maintaining perceptual stability, based either on the spatial relationships among visible objects or internal copies of its own motor comm...

journal_title：Journal of neurophysiology

authors： Churan J,Guitton D,Pack CC

更新日期：2011-10-01 00:00:00

abstract：:1. Single-unit and multiunit activities were recorded at the area 17-18 border of each cortical hemisphere in paralyzed cats anesthetized with nitrous oxide supplemented with halothane. Cross-correlation histograms (CCHs) were computed between 86 pairs of single units and 99 pairs of multiunit activities. Visually evo...

journal_title：Journal of neurophysiology

authors： Nowak LG,Munk MH,Nelson JI,James AC,Bullier J

更新日期：1995-12-01 00:00:00

abstract：:We examined whether presenting an odor with a positive, neutral, or negative name would influence how people perceive it. In experiment 1, 40 participants rated 15 odors for their pleasantness, intensity, and arousal. In experiment 2, 30 participants passively smelled 10 odors while their skin conductance (SC), heart ...

journal_title：Journal of neurophysiology

authors： Djordjevic J,Lundstrom JN,Clément F,Boyle JA,Pouliot S,Jones-Gotman M

更新日期：2008-01-01 00:00:00

abstract：:Prominent arginine-vasopressin (AVP) binding and AVP V(1) type receptors are expressed early in the developing rat spinal cord. We sought to characterize their influence on neural excitability by using patch-clamp techniques to record AVP-induced responses from a population of motoneurons and interneurons in neonatal ...

journal_title：Journal of neurophysiology

authors： Oz M,Kolaj M,Renaud LP

更新日期：2001-09-01 00:00:00

abstract：:To investigate how hippocampal neurons encode sound stimuli, and the conjunction of sound stimuli with the animal's position in space, we recorded from neurons in the CA1 region of hippocampus in rats while they performed a sound discrimination task. Four different sounds were used, two associated with water reward on...

journal_title：Journal of neurophysiology

authors： Itskov PM,Vinnik E,Honey C,Schnupp J,Diamond ME

更新日期：2012-04-01 00:00:00

abstract：:We presented optic flow and real movement heading stimuli while recording MSTd neuronal activity. Monkeys were alternately engaged in three tasks: visual detection of optic flow heading perturbations, vestibular detection of real movement heading perturbations, and auditory detection of brief tones. Push-button RTs we...

journal_title：Journal of neurophysiology

authors： Page WK,Duffy CJ

更新日期：2018-01-01 00:00:00

abstract：:When speed changes during locomotion, both temporal and spatial parameters of the pattern must adjust. Moreover, at slow speeds the step-to-step pattern becomes increasingly variable. The objectives of the present study were to assess if the spinal locomotor network adjusts both temporal and spatial parameters from sl...

journal_title：Journal of neurophysiology

authors： Dambreville C,Labarre A,Thibaudier Y,Hurteau MF,Frigon A

更新日期：2015-08-01 00:00:00

abstract：:Alzheimer's disease (AD) is a progressive neurodegenerative condition characterized by profound deficits in memory and cognitive function. Neuropathological hallmarks of the disease include a loss of basal forebrain cholinergic neurons and the deposition of beta-amyloid peptide (Abeta) in neuritic plaques. At a cellul...

journal_title：Journal of neurophysiology

authors： Fu W,Jhamandas JH

更新日期：2003-11-01 00:00:00

abstract：:Cholinergic signaling coupled to sensory-driven neuronal depolarization is essential for modulating lasting changes in deep-layer neural excitability and experience-dependent plasticity in the primary auditory cortex. However, the underlying cellular mechanism(s) associated with coincident cholinergic receptor activat...

journal_title：Journal of neurophysiology

authors： Fu X,Ye H,Jia H,Wang X,Chomiak T,Luo F

更新日期：2019-12-01 00:00:00

abstract：:Modulation of dendrodendritic synapses by the noradrenergic system in the accessory olfactory bulb (AOB) plays a key role in the formation of memory in olfactory-mediated behaviors. We have recently shown that noradrenaline (NA) inhibits mitral cells by increasing gamma-aminobutyric acid inhibitory input onto mitral c...

journal_title：Journal of neurophysiology

authors： Smith RS,Weitz CJ,Araneda RC

更新日期：2009-08-01 00:00:00

abstract：:Reward and punishment have opposite affective value but are both processed by the cingulate cortex. However, it is unclear whether the positive and negative affective values of monetary reward and punishment are processed by separate or common subregions of the cingulate cortex. We performed a functional magnetic reso...

journal_title：Journal of neurophysiology

authors： Fujiwara J,Tobler PN,Taira M,Iijima T,Tsutsui K

更新日期：2009-06-01 00:00:00

abstract：:1. In decerebrate paralyzed cats, we observed the responses of ventral and dorsal medullary inspiratory (I) neurons to two types of vagal afferent input that shorten neural I: lung inflation and vagal electrical stimulation. 2. A study population of 15 I neurons whose firing patterns suggested involvement in the inspi...

journal_title：Journal of neurophysiology

authors： Cohen MI,Huang WX,Barnhardt R,See WR

更新日期：1993-05-01 00:00:00

abstract：:During early brain development, γ-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the adult brain, has been thought to be an important source of excitatory neurotransmission. This view, however, was recently challenged by a series of studies that claim that the excitatory effect of GABA is due to non...

journal_title：Journal of neurophysiology

authors： Khakhalin AS

更新日期：2011-09-01 00:00:00

abstract：:The brain's ability to integrate information from different senses is acquired only after extensive sensory experience. However, whether early life experience instantiates a general integrative capacity in multisensory neurons or one limited to the particular cross-modal stimulus combinations to which one has been exp...

journal_title：Journal of neurophysiology

authors： Xu J,Yu L,Stanford TR,Rowland BA,Stein BE

更新日期：2015-02-01 00:00:00

abstract：:Neural correlates of gap detection in three auditory cortical fields in the cat. Mimimum detectable gaps in noise in humans are independent of the position of the gap, whereas in cat primary auditory cortex (AI) they are position dependent. The position dependence in other cortical areas is not known and may resolve t...

journal_title：Journal of neurophysiology

authors： Eggermont JJ

更新日期：1999-05-01 00:00:00

abstract：:To examine the activity of somatosensory cortex (S1) neurons to self-generated shear forces on the index and thumb, two monkeys were trained to grasp a stationary metal tab with a key grip and exert forces without the fingers slipping in one of four orthogonal directions for 1 s. A majority (∼85%) of slowly adapting a...

journal_title：Journal of neurophysiology

authors： Fortier-Poisson P,Langlais JS,Smith AM

更新日期：2016-01-01 00:00:00

abstract：:The responses of many neurons in primary visual cortex are modulated by stimuli outside the classical receptive field in ways that may contribute to integrative processes like scene segmentation. To explore this issue, single-unit neuronal responses were recorded in monkey cortical areas V1 and V2 to visual stimuli co...

journal_title：Journal of neurophysiology

authors： Marcus DS,Van Essen DC

更新日期：2002-11-01 00:00:00

abstract：:1. We have studied the responses of neurons in the lateral and descending vestibular nuclei of decerebrate cats to stimulation of neck receptors, produced by rotating the body in vertical planes with the head stationary. The responses to such neck stimulation were compared with the responses to vestibular stimulation ...

journal_title：Journal of neurophysiology

authors： Kasper J,Schor RH,Wilson VJ

更新日期：1988-11-01 00:00:00

abstract：:An imbalance between the strengths of excitatory and inhibitory synaptic inputs has been proposed as the cellular basis of autism and related neurodevelopmental disorders. Previous studies examining spontaneous levels of excitatory and inhibitory neurotransmission in the forebrain regions of methyl-CpG-binding protein...

journal_title：Journal of neurophysiology

authors： Nelson ED,Bal M,Kavalali ET,Monteggia LM

更新日期：2011-07-01 00:00:00

abstract：:PSD-95-like, disc-large (DLG) family membrane-associated guanylate kinase proteins (PSD/DLG-MAGUKs) are essential for regulating synaptic AMPA receptor (AMPAR) function and activity-dependent trafficking of AMPARs. Using a molecular replacement strategy to replace endogenous PSD-95 with SAP97β, we show that the protot...

journal_title：Journal of neurophysiology

authors： Liu M,Lewis LD,Shi R,Brown EN,Xu W

更新日期：2014-02-01 00:00:00

abstract：:1. A compartmental model was employed to investigate the electrical behavior of a dendritic spine having excitable membrane at the spine head. Here we used the Hodgkin and Huxley equations to generate excitable membrane properties; in some cases the kinetics were modified to get a longer duration action potential. Pas...

journal_title：Journal of neurophysiology

authors： Segev I,Rall W

更新日期：1988-08-01 00:00:00

abstract：:The reward value of a stimulus can be learned through two distinct mechanisms: reinforcement learning through repeated stimulus-reward pairings and abstract inference based on knowledge of the task at hand. The reinforcement mechanism is often identified with midbrain dopamine neurons. Here we show that a neural pathw...

journal_title：Journal of neurophysiology

authors： Bromberg-Martin ES,Matsumoto M,Hong S,Hikosaka O

更新日期：2010-08-01 00:00:00

abstract：:Extraretinal information, such as corollary discharge (CD), is hypothesized to help compensate for saccade-induced visual input disruptions. However, support for this hypothesis is largely for one-dimensional transsaccadic visual changes, with little comprehensive information on the spatial characteristics. Here we sy...

journal_title：Journal of neurophysiology

authors： Jayet Bray LC,Bansal S,Joiner WM

更新日期：2016-03-01 00:00:00

abstract：:1. Physiological responses of hippocampal pyramidal neurons in primary culture to prolonged glutamate (GLU) exposure (500 microM in all experiments) were studied with the use of patch electrodes and whole-cell current-clamp recording techniques. In some experiments, perforated patch recordings were employed with elect...

journal_title：Journal of neurophysiology

authors： Coulter DA,Sombati S,DeLorenzo RJ

更新日期：1992-08-01 00:00:00

abstract：:Avian auditory and vestibular hair cells regenerate after damage by ototoxic drugs, but until recently there was little evidence that regenerated vestibular hair cells function normally. In an earlier study we showed that the vestibuloocular reflex (VOR) is eliminated with aminoglycoside antibiotic treatment and recov...

journal_title：Journal of neurophysiology

authors： Goode CT,Carey JP,Fuchs AF,Rubel EW

更新日期：1999-03-01 00:00:00

abstract：:Fast inhibitory synaptic transmission in the medial vestibular nucleus (MVN) is mediated by GABA(A) receptors (GABA(A)Rs) and glycine receptors (GlyRs). To assess their relative contribution to inhibition in the MVN, we recorded miniature inhibitory postsynaptic currents (mIPSCs) in physiologically characterized type ...

journal_title：Journal of neurophysiology

authors： Camp AJ,Callister RJ,Brichta AM

更新日期：2006-05-01 00:00:00

abstract：:We previously reported that neurons in the mediodorsal thalamic nucleus (MD) are topographically organized and express spatial and nonspatial coding properties similar to those of the prefrontal areas with which they are connected. In the course of mapping the dorsal thalamus, we also studied neurons in a subset of th...

journal_title：Journal of neurophysiology

authors： Tanibuchi I,Goldman-Rakic PS

更新日期：2005-01-01 00:00:00

abstract：:Glycinergic and GABAergic inhibition are juxtaposed at one retinal synaptic layer yet likely perform different functions. These functions have usually been evaluated using receptor antagonists. In examining retinal glycine receptors, we were surprised to find that commonly used concentrations of GABA antagonists block...

journal_title：Journal of neurophysiology

authors： Wang P,Slaughter MM

更新日期：2005-06-01 00:00:00

abstract：:1. To analyze further the sensory mechanisms for triggering the lordosis reflex, single-unit (n = 345) activity was recorded extracellularly from spinal segments L5-S1 of urethan-anesthetized female rats. Unit responses to pressure on the skin (necessary and sufficient for evoking lordosis) and other mechanical stimul...

journal_title：Journal of neurophysiology

authors： Kow LM,Zemlan FP,Pfaff DW

更新日期：1980-01-01 00:00:00

abstract：:In many regions of the vertebrate brain, microcircuits generate local recurrent activity that aids in the processing and encoding of incoming afferent inputs. Local recurrent activity can amplify, filter, and temporally and spatially parse out incoming input. Determining how these microcircuits function is of great in...

journal_title：Journal of neurophysiology

authors： Liu Z,Ciarleglio CM,Hamodi AS,Aizenman CD,Pratt KG

更新日期：2016-03-01 00:00:00