Abstract:
:1. In decerebrate paralyzed cats, we observed the responses of ventral and dorsal medullary inspiratory (I) neurons to two types of vagal afferent input that shorten neural I: lung inflation and vagal electrical stimulation. 2. A study population of 15 I neurons whose firing patterns suggested involvement in the inspiratory OFF-switch (IOS) was selected on the basis of two criteria: late onset of firing and excitation by vagal inputs. 3. Firing in relation to the end of I showed two types of response to vagal inputs. The pre-expiratory onset time (time from initial spike to end of I) was either unchanged (type 1 response in 5/15 neurons) or significantly changed (type 2 response in 10/15 neurons). 4. It is suggested that type 1 neurons, whose firing patterns remain closely locked to the end of I despite considerable changes of I duration, are involved in promoting the IOS, whereas type 2 neurons are either not involved (e.g., late-onset premotor neurons) or are involved at an earlier temporal processing stage.
journal_name
J Neurophysioljournal_title
Journal of neurophysiologyauthors
Cohen MI,Huang WX,Barnhardt R,See WRdoi
10.1152/jn.1993.69.5.1784subject
Has Abstractpub_date
1993-05-01 00:00:00pages
1784-7issue
5eissn
0022-3077issn
1522-1598journal_volume
69pub_type
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