Excitatory actions of noradrenaline and metabotropic glutamate receptor activation in granule cells of the accessory olfactory bulb.

abstract：:We measured synaptic responses to complex stimulus trains in the calyx of Held and used the data to test how well several vesicle-release models could capture the observed dynamics. We tested stimulation protocols consisting of Poisson-distributed activity with periodically changing mean frequencies, trains with const...

journal_title：Journal of neurophysiology

authors： Hermann J,Grothe B,Klug A

更新日期：2009-01-01 00:00:00

abstract：:Neurons in monkey orbitofrontal cortex (OF) are known to respond to reward-predicting cues with a strength that depends on the value of the predicted reward as determined 1) by intrinsic attributes including size and quality and 2) by extrinsic factors including the monkey's state of satiation and awareness of what ot...

journal_title：Journal of neurophysiology

authors： Roesch MR,Olson CR

更新日期：2005-10-01 00:00:00

abstract：:Motor networks such as the pyloric network of the stomatogastric ganglion often require descending neuromodulatory inputs to initiate, regulate, and modulate their activity and their synaptic connectivity to manifest physiologically appropriate output. Prolonged removal of these descending inputs often results in a co...

journal_title：Journal of neurophysiology

authors： Nahar J,Lett KM,Schulz DJ

更新日期：2012-08-01 00:00:00

abstract：:1. Compartmental models were used to compute the time constants and coefficients of voltage and current transients in hypothetical neurons having tapering dendrites or soma shunt and in a serially reconstructed motoneuron with soma shunt. These time constants and coefficients were used in equivalent cylinder formulas ...

journal_title：Journal of neurophysiology

authors： Holmes WR,Rall W

更新日期：1992-10-01 00:00:00

abstract：:Previous studies have reported an important relationship between increasing age, vestibular impairment, and increased risk of falls. Recently, noisy galvanic vestibular stimulation (nGVS) has been shown to improve postural control in older adults during and potentially following stimulation. However, this effect of nG...

journal_title：Journal of neurophysiology

authors： Nooristani M,Bigras C,Lafontaine L,Bacon BA,Maheu M,Champoux F

更新日期：2020-12-09 00:00:00

abstract：:1. The mismatch response, or mismatch negativity (MMN), is a neurophysiologic response to stimulus change. In humans and other animals, the MMN may underlie the ability to discriminate acoustic differences, a fundamental aspect of auditory perception. 2. This study investigated the role of the thalamus in the generati...

journal_title：Journal of neurophysiology

authors： Kraus N,McGee T,Littman T,Nicol T,King C

更新日期：1994-09-01 00:00:00

abstract：:The activity of jaw muscle receptors was studied by recording neurons in the mesencephalic nucleus of the trigeminal nerve in monkeys trained to control the position and movement of their mandible. Jaw position was measured by a weighted lever resting on the mandibular incisors. The force required to maintain the posi...

journal_title：Journal of neurophysiology

authors： Larson CR,Finocchio DV,Smith A,Luschei ES

更新日期：1983-07-01 00:00:00

abstract：:In adults, locomotor movements are accommodated to various support surface conditions by means of specific anticipatory locomotor adjustments and changes in the intersegmental coordination. Here we studied the kinematic strategies of toddlers at the onset of independent walking when negotiating various support surface...

journal_title：Journal of neurophysiology

authors： Dominici N,Ivanenko YP,Cappellini G,Zampagni ML,Lacquaniti F

更新日期：2010-03-01 00:00:00

abstract：:Effective connectivity between cortical areas decreases during slow wave sleep. This decline can be observed in the reduced interareal propagation of activity evoked either directly in cortex by transcranial magnetic stimulation (TMS) or by sensory stimulation. We present here a large-scale model of the thalamocortica...

journal_title：Journal of neurophysiology

authors： Esser SK,Hill S,Tononi G

更新日期：2009-10-01 00:00:00

abstract：:Humans and animals value the opportunity to choose by preferring alternatives that offer more rather than fewer choices. This preference for choice may arise not only from an increased probability of obtaining preferred outcomes but also from the freedom it provides. We used human neuroimaging to investigate the neura...

journal_title：Journal of neurophysiology

authors： Fujiwara J,Usui N,Park SQ,Williams T,Iijima T,Taira M,Tsutsui K,Tobler PN

更新日期：2013-10-01 00:00:00

abstract：:Long-term potentiation (LTP) in rat spinal dorsal horn neurons was induced by electrical high-frequency stimulation (HFS) of afferent C fibers. LTP is generally assumed to be a key mechanism of spinal sensitization. To determine the contribution of skin and muscle afferents to LTP induction, the sural nerve (SU, pure ...

journal_title：Journal of neurophysiology

authors： Zhang J,Hoheisel U,Klein T,Magerl W,Mense S,Treede RD

更新日期：2016-02-01 00:00:00

abstract：:Feedback control of our limbs must account for the unexpected offset of mechanical perturbations. Here we examine the evoked activity of elbow flexor and extensor muscles to torque pulses lasting 22-152 ms and how torque offset impacts activity in the long-latency (45-100 ms) and voluntary epochs (120-180 ms). For eac...

journal_title：Journal of neurophysiology

authors： Kurtzer I,Pruszynski JA,Scott SH

更新日期：2010-06-01 00:00:00

abstract：:Neuron loss, axon sprouting, and the formation of new synaptic circuits have been hypothesized to contribute to seizures in temporal lobe epilepsy (TLE). Using the kainate-treated rat, we examined how alterations in the density of CA1 pyramidal cells and interneurons, and subsequent sprouting of CA1 pyramidal cell axo...

journal_title：Journal of neurophysiology

authors： Smith BN,Dudek FE

更新日期：2001-01-01 00:00:00

abstract：:Glutamate, the neurotransmitter, enhances rapid-eye-movement (REM) sleep when microinjected into the brain stem pedunculopontine tegmentum (PPT) of the cat and rat. Glutamate and its various receptors are normally present in the PPT cholinergic cell compartment. The aim of this study was to identify which specific rec...

journal_title：Journal of neurophysiology

authors： Datta S

更新日期：2002-04-01 00:00:00

abstract：:The cerebellum has long been recognized to play an important role in motor adaptation. Individuals with cerebellar ataxia exhibit impaired learning in visuomotor adaptation tasks such as prism adaptation and force field learning. Both types of tasks involve the adjustment of an internal model to compensate for an exte...

journal_title：Journal of neurophysiology

authors： Schlerf JE,Xu J,Klemfuss NM,Griffiths TL,Ivry RB

更新日期：2013-02-01 00:00:00

abstract：:Single neurons were recorded from the ventral posteromedial thalamic nucleus (VPM) of urethan-anesthetized rats. Six of these animals were intact, 28 sustained kainic acid (KA) lesions of trigeminal nucleus principalis (PrV), and 9 received similar lesions of trigeminal subnucleus interpolaris (SpVi). Four animals sus...

journal_title：Journal of neurophysiology

authors： Rhoades RW,Belford GR,Killackey HP

更新日期：1987-05-01 00:00:00

abstract：:Interpretation of hemodynamic responses in epilepsy is hampered by an incomplete understanding of the underlying neurovascular coupling, especially the contributions of excitation and inhibition. We made simultaneous multimodal recordings of local field potentials (LFPs), firing of individual neurons, blood flow, and ...

journal_title：Journal of neurophysiology

authors： Saillet S,Quilichini PP,Ghestem A,Giusiano B,Ivanov AI,Hitziger S,Vanzetta I,Bernard C,Bénar CG

更新日期：2016-03-01 00:00:00

abstract：:Previous experimental results from our laboratory demonstrated that monocyte chemoattractant protein-1 (MCP-1) depolarizes or increases the excitability of nociceptive neurons in the intact dorsal root ganglion (DRG) after a chronic compression of the DRG (CCD), an injury that upregulates neuronal expression of both M...

journal_title：Journal of neurophysiology

authors： Sun JH,Yang B,Donnelly DF,Ma C,LaMotte RH

更新日期：2006-11-01 00:00:00

abstract：:We have demonstrated that 4-aminopyridine-3-methanol (4-AP-3-MeOH), a 4-aminopyridine derivative, significantly restores axonal conduction in stretched spinal cord white-matter strips and shows no preference in restoring large and small axons. This compound is 10 times more potent when compared with 4-AP and other der...

journal_title：Journal of neurophysiology

authors： Sun W,Smith D,Fu Y,Cheng JX,Bryn S,Borgens R,Shi R

更新日期：2010-01-01 00:00:00

abstract：:Biological gain mechanisms regulate the sensitivity and dynamics of signaling pathways at the systemic, cellular, and molecular levels. In the sympathetic nervous system, gain in sensory-motor feedback loops is essential for homeostatic regulation of blood pressure and body temperature. This study shows how synaptic c...

journal_title：Journal of neurophysiology

authors： Wheeler DW,Kullmann PH,Horn JP

更新日期：2004-11-01 00:00:00

abstract：:Self-motion generates patterns of optic flow on the retina. Neurons in the dorsal part of the medial superior temporal area (MSTd) are selective for these optic flow patterns. It has been shown that neurons in this area that are selective for expanding optic flow fields are involved in heading judgments. We wondered h...

journal_title：Journal of neurophysiology

authors： Xu H,Wallisch P,Bradley DC

更新日期：2014-06-01 00:00:00

abstract：:The study of quadrupeds has furnished most of our understanding of mammalian locomotion. To allow a more direct comparison of coordination between the four limbs in humans and quadrupeds, we studied crawling in the human, a behavior that is part of normal human development and mechanically more similar to quadrupedal ...

journal_title：Journal of neurophysiology

authors： Patrick SK,Noah JA,Yang JF

更新日期：2009-02-01 00:00:00

abstract：:The widespread noradrenergic innervation in the brain promotes arousal and learning by molecular mechanisms that remain largely undefined. Recent work shows that the β(2)-adrenergic receptor (β(2)AR) is linked to the AMPA-type glutamate receptor subunit GluA1 via stargazin and PSD-95 (Joiner ML, Lise MF, Yuen EY, Kam ...

journal_title：Journal of neurophysiology

authors： Qian H,Matt L,Zhang M,Nguyen M,Patriarchi T,Koval OM,Anderson ME,He K,Lee HK,Hell JW

更新日期：2012-05-01 00:00:00

abstract：:Hippocampal mossy fiber axons simultaneously activate CA3 pyramidal cells and stratum lucidum interneurons (SLINs), the latter providing feedforward inhibition to control CA3 pyramidal cell excitability. Filopodial extensions of giant boutons of mossy fibers provide excitatory synaptic input to the SLIN. These filopod...

journal_title：Journal of neurophysiology

authors： Pan E,Zhao Z,McNamara JO

更新日期：2019-02-01 00:00:00

abstract：:Fine flexible wire microelectrodes chronically implanted in the fifth lumbar ventral root (L5 VR) of 17 cats rendered stable records of the natural discharge patterns of 164 individual axons during locomotion on a treadmill. Fifty-one out of 164 axons were identified as motoneurons projecting to the anterior thigh mus...

journal_title：Journal of neurophysiology

authors： Hoffer JA,Loeb GE,Marks WB,O'Donovan MJ,Pratt CA,Sugano N

更新日期：1987-02-01 00:00:00

abstract：:The vestibular system operates in a push-pull fashion using signals from both labyrinths and an intricate bilateral organization. Unilateral vestibular lesions cause well-characterized motor deficits that are partially compensated over time and whose neural correlates have been traced in the mean response modulation o...

journal_title：Journal of neurophysiology

authors： Yu XJ,Thomassen JS,Dickman JD,Newlands SD,Angelaki DE

更新日期：2014-08-15 00:00:00

abstract：:The effect of HCO(3)(-)/CO(2) on membrane properties of isolated hippocampal CA1 neurons was studied with the use of the whole cell configuration of the patch-clamp technique. Neurons were acutely dissociated from 21- to 30-day-old mice. In the current-clamp mode, HCO(3)(-)/CO(2) significantly hyperpolarized CA1 neuro...

journal_title：Journal of neurophysiology

authors： Gu XQ,Yao H,Haddad GG

更新日期：2000-11-01 00:00:00

abstract：:Recent studies conducted in our laboratory have suggested that the tongue primary motor cortex (i.e., tongue-MI) plays a critical role in the control of voluntary tongue movements in the primate. However, the possible involvement of tongue-MI in semiautomatic tongue movements, such as those in swallowing, remains unkn...

journal_title：Journal of neurophysiology

authors： Martin RE,Murray GM,Kemppainen P,Masuda Y,Sessle BJ

更新日期：1997-09-01 00:00:00

abstract：:Over the past 3 decades, various algorithms used to decompose the electromyographic (EMG) signal into its constituent motor unit action potentials (MUAPs) have been reported. All are limited to decomposing EMG signals from isometric contraction. In this report, we describe a successful approach to decomposing the surf...

journal_title：Journal of neurophysiology

authors： De Luca CJ,Chang SS,Roy SH,Kline JC,Nawab SH

更新日期：2015-03-15 00:00:00

abstract：:Several models exist for explaining primary visual cortex (V1) orientation tuning. The modified feedforward model (MFM) and the recurrent model (RM) are major examples. We have implemented these two models, at the same level of detail, alongside a few newer variations, and thoroughly compared their receptive-field str...

journal_title：Journal of neurophysiology

authors： Teich AF,Qian N

更新日期：2006-07-01 00:00:00