MCP-1 enhances excitability of nociceptive neurons in chronically compressed dorsal root ganglia.

abstract：:Substance P (SP) hyperpolarizes approximately 80% of ferret vagal sensory neurons (nodose ganglion neurons) via NK-1 receptor-mediated activation of a potassium current (IK). A depolarizing current activated by membrane hyperpolarization could minimize the SP-induced hyperpolarization. Such a current exists in 65% of ...

journal_title：Journal of neurophysiology

authors： Jafri MS,Weinreich D

更新日期：1998-02-01 00:00:00

abstract：:1. We recorded single cell activities in the caudate nucleus of the monkeys trained to perform a series of visuomotor tasks. In the first part of this paper, we summarize the types and locations of neurons in the monkey caudate nucleus. In the second part, we report the characteristics of neurons related to saccadic e...

journal_title：Journal of neurophysiology

authors： Hikosaka O,Sakamoto M,Usui S

更新日期：1989-04-01 00:00:00

abstract：:We have previously reported that short-term (48-72 h) exposure to the GABA-modulatory steroid 3alpha-OH-5alpha-pregnan-20-one (3alpha,5alpha-THP) increases expression of the alpha4 subunit of the GABA(A) receptor (GABAR) in the hippocampus of adult rats. This change in subunit composition was accompanied by altered ph...

journal_title：Journal of neurophysiology

authors： Hsu FC,Waldeck R,Faber DS,Smith SS

更新日期：2003-04-01 00:00:00

abstract：:1. We studied the organization of motor units in the tenuissimus (TEN) muscle of pentobarbital-anesthetized cats. The cat TEN is a long, delicate straplike muscle that spans hip and knee, which has a very flat length-tension curve through 22 mm of length change. 2. The TEN motor nucleus, labeled by retrograde transpor...

journal_title：Journal of neurophysiology

authors： Lev-Tov A,Pratt CA,Burke RE

更新日期：1988-04-01 00:00:00

abstract：:To estimate contour-orientation sensitivity of the cat and the degree to which precortical processing contributes to such estimates, the amplitude of visually evoked potentials (VEP) recorded from the visual cortex of cats in response to a visual stimulus (S2) presented at various intervals after presentation of anoth...

journal_title：Journal of neurophysiology

authors： Tootle JS,Berkley MA

更新日期：1985-05-01 00:00:00

abstract：:1. Intrasomal recordings were made with microelectrodes from 153 warm (infrared) neurons in the trigeminal ganglia of 36 crotaline snakes, Trimeresurus flavoviridis. Background discharges were observed at room temperature. The 153 warm neurons were classified into two groups: 81 were sensitive to less than or equal to...

journal_title：Journal of neurophysiology

authors： Terashima S,Liang YF

更新日期：1991-08-01 00:00:00

abstract：:Recognition of sound patterns must be largely independent of level and of masking or jamming background sounds. Auditory patterns of relevance in numerous environmental sounds, species-specific vocalizations and speech are frequency modulations (FM). Level-dependent activation of the human auditory cortex (AC) in resp...

journal_title：Journal of neurophysiology

authors： Brechmann A,Baumgart F,Scheich H

更新日期：2002-01-01 00:00:00

abstract：:Studies on animals have shown that noise-induced hearing loss is followed by an increase of spontaneous firing at several stages of the central auditory system. This central hyperactivity has been suggested to underpin the perception of tinnitus. It was shown that decreasing cochlear activity can abolish the noise-ind...

journal_title：Journal of neurophysiology

authors： Noreña AJ,Mulders WH,Robertson D

更新日期：2015-01-01 00:00:00

abstract：:1. To obtain a comprehensive map of the ascending projection of the midbrain periaqueductal gray, small amounts of [3H]leucine were injected into discrete regions of the periaqueductal gray (PAG) of the monkey. 2. Despite the fact that different regions of the PAG were injected in separate animals, the majority of the...

journal_title：Journal of neurophysiology

authors： Mantyh PW

更新日期：1983-03-01 00:00:00

abstract：:We report a novel phenomenon produced by focused ultrasound (US) that may be important for understanding its effects on cell membranes. When a US burst (2.1 MHz, 1-mm focal diameter, 0.1-1 MPa) was focused on a motor axon of the crayfish neuromuscular junction, it consistently produced a fast hyperpolarization, which ...

journal_title：Journal of neurophysiology

authors： Lin JW,Yu F,Müller WS,Ehnholm G,Okada Y

更新日期：2019-02-01 00:00:00

abstract：:Adult neuronal phenotype is maintained, at least in part, by the sensitivity of individual neurons to a specific selection of neurotrophic factors and the availability of such factors in the neurons' environment. Nerve growth factor (NGF) increases the functional expression of Na(+) channel currents (I(Na)) and both N...

journal_title：Journal of neurophysiology

authors： Ford CP,Wong KV,Lu VB,Posse de Chaves E,Smith PA

更新日期：2008-03-01 00:00:00

abstract：:Thalamocortical neurons integrate sensory and cortical activity and are regulated by input from inhibitory neurons in the thalamic reticular nucleus. Evidence suggests that during bursts of action potentials, dendritic calcium transients are seen throughout the dendritic tree of thalamocortical cells. Here, we review ...

journal_title：Journal of neurophysiology

authors： Hulme SR,Connelly WM

更新日期：2014-11-01 00:00:00

abstract：:Human subjects chose between two color-coded reach targets using multicolored checkerboard-like decision cues (DCs) that presented variable amounts of conflicting sensory evidence supporting both target choices. Different DCs contained different numbers of small squares of the two target colors. The most ambiguous DCs...

journal_title：Journal of neurophysiology

authors： Coallier É,Kalaska JF

更新日期：2014-12-01 00:00:00

abstract：:Subfornical organ (SFO) neurons exhibit heterogeneity in current expression and spiking behavior, where the two major spiking phenotypes appear as tonic and burst firing. Insight into the mechanisms behind this heterogeneity is critical for understanding how the SFO, a sensory circumventricular organ, integrates and s...

journal_title：Journal of neurophysiology

authors： Medlock L,Shute L,Fry M,Standage D,Ferguson AV

更新日期：2018-11-01 00:00:00

abstract：:Prefrontal cortex (PFC) dopamine D1/5 receptors modulate long- and short-term neuronal plasticity that may contribute to cognitive functions. Synergistic to synaptic strength modulation, direct postsynaptic D1/5 receptor activation also modulates voltage-dependent ionic currents that regulate spike firing, thus alteri...

journal_title：Journal of neurophysiology

authors： Chen L,Bohanick JD,Nishihara M,Seamans JK,Yang CR

更新日期：2007-03-01 00:00:00

abstract：:1. The responses of onset units in the cochlear nucleus of the anesthetized guinea pig have been measured to single tones, two-tone complexes, and broadband noise (BBN; 20-kHz bandwidth). The onset units were subdivided into three groups, onset-I (OnI), onset-L (OnL), and onset-C (OnC), on the basis of a decision tree...

journal_title：Journal of neurophysiology

authors： Winter IM,Palmer AR

更新日期：1995-01-01 00:00:00

abstract：:We have previously shown that the Coriolis torques that result when an arm movement is performed during torso rotation do not affect movement trajectory. Our purpose in the present study was to examine whether torso motion-induced Coriolis and other interaction torques are counteracted during a turn and reach (T&R) mo...

journal_title：Journal of neurophysiology

authors： Pigeon P,Dizio P,Lackner JR

更新日期：2013-09-01 00:00:00

abstract：:The posterior nucleus of thalamus (PO) is a higher-order nucleus involved in sensorimotor processing, including nociception. An important characteristic of PO is its wide range of activity profiles that vary across states of arousal, thought to underlie differences in somatosensory perception subject to attention and ...

journal_title：Journal of neurophysiology

authors： Park A,Li Y,Masri R,Keller A

更新日期：2017-07-01 00:00:00

abstract：:The synaptic plasticity literature has focused on establishing necessity and sufficiency as two essential and distinct features in causally relating a signaling molecule to plasticity induction, an approach that has been surprisingly lacking in the intrinsic plasticity literature. In this study, we complemented the re...

journal_title：Journal of neurophysiology

authors： Ashhad S,Johnston D,Narayanan R

更新日期：2015-04-01 00:00:00

abstract：:We demonstrate distinct α- (7-14 Hz) and β-band (15-30 Hz) rhythms in rat somatosensory cortex in vivo using epidural electrocorticography recordings. Moreover, we show in rats that a genuine β-rhythm coexists alongside β-activity that reflects the second harmonic of the arch-shaped somatosensory α-rhythm. This demons...

journal_title：Journal of neurophysiology

authors： Fransen AM,Dimitriadis G,van Ede F,Maris E

更新日期：2016-06-01 00:00:00

abstract：:1. The rostromesial agranular frontal cortex of macaque monkey (Macaca fuscata), traditionally defined as the supplementary motor area (SMA), was studied using various physiological techniques to delineate two different areas rostrocaudally. 2. Field and unitary responses to electrical stimulation of the primary motor...

journal_title：Journal of neurophysiology

authors： Matsuzaka Y,Aizawa H,Tanji J

更新日期：1992-09-01 00:00:00

abstract：:1. Eleven adult cats were trained to stop inspiration in response to a conditioning stimulus. The conditioning stimuli were presented at the onset of inspiration at intervals of approximately 20-30 s. Intratracheal pressures, diaphragmatic activity, and the extracellular activity of single medullary respiratory neuron...

journal_title：Journal of neurophysiology

authors： Orem J

更新日期：1989-11-01 00:00:00

abstract：:The transient potassium current (I(A)) plays an important role in shaping the firing properties of pyloric neurons in the stomatogastric ganglion (STG) of the spiny lobster, Panulirus interruptus. The shal gene encodes I(A) in pyloric neurons. However, when we over-expressed the lobster Shal protein by shal RNA inject...

journal_title：Journal of neurophysiology

authors： Zhang Y,MacLean JN,An WF,Lanning CC,Harris-Warrick RM

更新日期：2003-04-01 00:00:00

abstract：:Two forms of undulatory locomotion in the lamprey (a lower vertebrate) have been described earlier: fast forward swimming (FFS) used for long distance migrations and slow backward swimming (SBS) used for escape from adverse tactile stimuli. In the present study, we describe another form of escape behavior: slow forwar...

journal_title：Journal of neurophysiology

authors： Islam SS,Zelenin PV

更新日期：2008-01-01 00:00:00

abstract：:We investigated adaptation to simple force field scaling to determine whether the same strategy is used as during adaptation to more complex changes in the mechanical environment. Subjects initially trained in a force field, consisting of a rightward lateral force with a parabolic spatial profile (PF). The field stren...

journal_title：Journal of neurophysiology

authors： Hinder MR,Milner TE

更新日期：2007-11-01 00:00:00

abstract：:1. Our previous study showed that two distinct postural modifications occurred when subjects were instructed to step, rather than maintain stance, in response to a backward surface translation: 1) the automatic postural responses to the surfaces perturbation were reduced in magnitude and 2) the anticipatory postural a...

journal_title：Journal of neurophysiology

authors： Burleigh A,Horak F

更新日期：1996-04-01 00:00:00

abstract：:The role of potassium channels in regulating spontaneous firing and sound-evoked responses in the central nucleus of the inferior colliculus was studied by recording single-unit activity before and during iontophoretic application of a nonspecific potassium channel blocker, tetraethylammonium (TEA). Tone bursts and si...

journal_title：Journal of neurophysiology

authors： Zhang H,Wu SH,Kelly JB

更新日期：2004-05-01 00:00:00

abstract：:1. Cats were prepared for chronic recordings from the lumbar enlargement of the spinal dorsal horn. At the beginning of each recording session, a tungsten microelectrode was advanced through the dura in a physiologically intact, awake, drug-free animal, until amplitude discrimination provided a single neuron with a re...

journal_title：Journal of neurophysiology

authors： Kishikawa K,Uchida H,Yamamori Y,Collins JG

更新日期：1995-08-01 00:00:00

abstract：:1. The regularity of the sustaining fiber (SF) steady-state discharge increases with the intensity of a uniform field of illumination. 2. In a high levels of illumination SFs exhibit a highly periodic or rhythmically bursting steady-state discharge. 3. The period of the burst cycle is independent of the light intensit...

journal_title：Journal of neurophysiology

authors： Glantz RM,Nudelman HB

更新日期：1976-11-01 00:00:00

abstract：:The GABA withdrawal syndrome (GWS) is a model of local status epilepticus consecutive to the interruption of a prolonged GABA infusion into the rat somatomotor cortex. Bursting patterns in slices from GWS rats include intrinsic bursts of action potentials (APs) induced by intracellular depolarizing current injection a...

journal_title：Journal of neurophysiology

authors： Silva-Barrat C,Szente M,Menini C,Velluti JC,Champagnat J

更新日期：2001-05-01 00:00:00