A general algorithm for calculation of recombination losses in ionization chambers exposed to ion beams.

Abstract:

PURPOSE:Dosimetry with ionization chambers in clinical ion beams for radiation therapy requires correction for recombination effects. However, common radiation protocols discriminate between initial and general recombination and provide no universal correction method for the presence of both recombination types in ion beams of charged particles heavier than protons. The advent of multiple field optimization in ion beams, allowing for complex patterns of dose delivery in both temporal and spatial domains, results in new challenges for recombination correction where the resulting recombination depends on the plan delivered. Here, the authors present the open source code IonTracks version 1.0, where the combined initial and general recombination effects in principle can be predicted for any ion beam with arbitrary particle-energy spectrum and temporal structure. METHODS:IonTracks uses track structure theory to distribute the charge carriers in ion tracks. The charge carrier movements are governed by a pair of coupled differential equations, based on fundamental physical properties as charge carrier drift, diffusion, and recombination, which are solved numerically while the initial and general charge carrier recombination is computed. A space charge screening of the electric field is taken into account and the algorithm furthermore allows an inclusion of a free-electron component. RESULTS:The algorithm is numerically stable and in accordance with experimentally validated theories for initial recombination in heavy ion tracks and general recombination in a proton beam. CONCLUSIONS:Given IonTracks' ability to handle arbitrary inputs, IonTracks can in principle be applied to any complex particle field in the spatial and temporal domain. IonTracks is validated against the Jaffé's and Boag's theory of recombination in pulsed beams of multiple ion species. IonTracks is able to calculate the correction factor for initial and general recombination losses in parallel-plate ionization chambers. Even if only few experimental data on recombination effects in ionization chambers are available today, the universal concept of IonTracks is not limited to the ions investigated here. Future experimental investigations of recombination in pulsed and possibly also continuous ion beams may be conducted with IonTracks, which ultimately may lead to a more precise prediction of recombination factors in complex radiation fields.

journal_name

Med Phys

journal_title

Medical physics

authors

Christensen JB,Tölli H,Bassler N

doi

10.1118/1.4962483

subject

Has Abstract

pub_date

2016-10-01 00:00:00

pages

5484

issue

10

eissn

0094-2405

issn

2473-4209

journal_volume

43

pub_type

杂志文章
  • Lung dosimetry in a linac-MRI radiotherapy unit with a longitudinal magnetic field.

    abstract:PURPOSE:There is interest in developing linac-MR systems for MRI-guided radiation therapy. To date, the designs for such linac-MR devices have been restricted to a transverse geometry where the static magnetic field is oriented perpendicular to the direction of the incident photon beam. This work extends possibilities ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3475942

    authors: Kirkby C,Murray B,Rathee S,Fallone BG

    更新日期:2010-09-01 00:00:00

  • A unified description of NMR imaging, data-collection strategies, and reconstruction.

    abstract::In nuclear magnetic resonance (NMR) imaging by the zeugmatographic methods, there is a common and unified theoretical description. All forms of two-dimensional and three-dimensional imaging involve NMR data which trace various geometric representations, in reciprocal transform space, of the subject's spatially blurred...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.595470

    authors: King KF,Moran PR

    更新日期:1984-01-01 00:00:00

  • Bremsstrahlung production at 50 MeV in different target materials and configurations.

    abstract::A combination of Monte Carlo, convolution, and experimental techniques have been used to investigate bremsstrahlung production at 50 MeV in full-range targets to produce narrow elementary photon beams for scanning. Calculations using the ITS 3.0 Monte Carlo system for various target designs, including particle transpo...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597681

    authors: Sätherberg A,Andreo P,Karlsson M

    更新日期:1996-04-01 00:00:00

  • The x-ray time of flight method for investigation of ghosting in amorphous selenium-based flat panel medical x-ray imagers.

    abstract::Amorphous selenium (a-Se) based real-time flat-panel imagers (FPIs) are finding their way into the digital radiology department because they offer the practical advantages of digital x-ray imaging combined with an image quality that equals or outperforms that of conventional systems. The temporal imaging characteristi...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2042248

    authors: Rau AW,Bakueva L,Rowlands JA

    更新日期:2005-10-01 00:00:00

  • Gadolinium neutron capture therapy for brain tumors: a computer study.

    abstract::A Monte Carlo computer study of the total dose distribution from neutrons and prompt gamma emissions (but excluding the contribution from conversion and Auger electrons) for gadolinium neutron capture therapy of brain tumors has been carried out in order to test the theoretic feasibility of this modality using commerc...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596761

    authors: Masiakowski JT,Horton JL,Peters LJ

    更新日期:1992-09-01 00:00:00

  • Novel scintillation detector design and performance for proton radiography and computed tomography.

    abstract:PURPOSE:Proton computed tomography (pCT) will enable accurate prediction of proton and ion range in a patient while providing the benefit of lower radiation exposure than in x-ray CT. The accuracy of the range prediction is essential for treatment planning in proton or ion therapy and depends upon the detector used to ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4939255

    authors: Bashkirov VA,Schulte RW,Hurley RF,Johnson RP,Sadrozinski HF,Zatserklyaniy A,Plautz T,Giacometti V

    更新日期:2016-02-01 00:00:00

  • Scattered radiation in chest radiography.

    abstract::Luminance scatter fractions were measured for patients and phantoms in various regions of the chest film. Scatter fractions were found to be highly variable, being quite high in the regions of the chest with a large equivalent tissue thickness (e.g. mediastinum, chest wall, and subdiaphragmatic areas). For example, ap...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.595027

    authors: Niklason LT,Sorenson JA,Nelson JA

    更新日期:1981-09-01 00:00:00

  • Development of a Monte Carlo multiple source model for inclusion in a dose calculation auditing tool.

    abstract:PURPOSE:The Imaging and Radiation Oncology Core Houston (IROC-H) (formerly the Radiological Physics Center) has reported varying levels of agreement in their anthropomorphic phantom audits. There is reason to believe one source of error in this observed disagreement is the accuracy of the dose calculation algorithms an...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12426

    authors: Faught AM,Davidson SE,Fontenot J,Kry SF,Etzel C,Ibbott GS,Followill DS

    更新日期:2017-09-01 00:00:00

  • Evaluation of the local dose enhancement in the combination of proton therapy and nanoparticles.

    abstract:PURPOSE:The outcome of radiotherapy can be further improved by combining irradiation with dose enhancers such as high-Z nanoparticles. Since 2004, spectacular results have been obtained when low-energy x-ray irradiations have been combined with nanoparticles. Recently, the same combination has been explored in hadron t...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4934370

    authors: Martínez-Rovira I,Prezado Y

    更新日期:2015-11-01 00:00:00

  • Tissue equivalence in clinical neutron dosimetry: comparison of dose distributions in nine tissue substitutes for a d(14)Be neutron beam.

    abstract::Depth dose distributions for a d(14)Be neutron beam, measured separately for total and gamma absorbed dose, are presented for nine tissue substitutes and for two field sizes. These data are used to examine methods to transform depth dose curves from one material to another. Best results are found when the local depths...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.595695

    authors: Hensley FW,Rassow J,Temme A

    更新日期:1985-05-01 00:00:00

  • SU-E-T-300: Monte Carlo Simulation of Single-Plane Magnetically Focused Narrow Proton Beams.

    abstract::Purpose To investigate narrow, elongated magnetically focused proton beams and compare their properties with passively collimated beams using Monte Carlo simulation. METHODS:We performed Geant4 Monte Carlo simulations involving a single quadrapole focusing magnet, thereby creating a flattened beam with an elongated e...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735386

    authors: McAuley G,Barnes S,Wroe A,Slater J

    更新日期:2012-06-01 00:00:00

  • Compensator models for fluence field modulated computed tomography.

    abstract:PURPOSE:Fluence field modulated computed tomography (FFMCT) presents a novel approach for acquiring CT images, whereby a patient model guides dynamically changing fluence patterns in an attempt to achieve task-based, user-prescribed, regional variations in image quality, while also controlling dose to the patient. This...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4829513

    authors: Bartolac S,Jaffray D

    更新日期:2013-12-01 00:00:00

  • An investigation on the use of removal-diffusion theory for BNCT treatment planning: a method for determining proper removal-diffusion parameters.

    abstract::This paper outlines a method for determining proper removal-diffusion parameters to be used in removal-diffusion theory calculations for the purpose of BNCT treatment planning. Additionally, this paper demonstrates that, given the proper choice of removal-diffusion parameters, removal-diffusion theory may provide an a...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1386424

    authors: Albertson BJ,Blue TE,Niemkiewicz J

    更新日期:2001-09-01 00:00:00

  • Technical Note: Evaluation of a 160-mm/256-row CT scanner for whole-heart quantitative myocardial perfusion imaging.

    abstract:PURPOSE:The authors investigated the performance of a recently introduced 160-mm/256-row CT system for low dose quantitative myocardial perfusion (MP) imaging of the whole heart. This platform is equipped with a gantry capable of rotating at 280 ms per full cycle, a second generation of adaptive statistical iterative r...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4957389

    authors: So A,Imai Y,Nett B,Jackson J,Nett L,Hsieh J,Wisenberg G,Teefy P,Yadegari A,Islam A,Lee TY

    更新日期:2016-08-01 00:00:00

  • The effects of the imaging system on the validity limits of the ray-optical approach to phase contrast imaging.

    abstract::A theoretical analysis of the x-ray phase contrast imaging and its validation via synchrotron radiation imaging is here presented. Two different mathematical models have been followed: the simpler ray-optical approach and the more rigorous Fresnel-Kirchoff diffraction theory. Subsequently, the conditions upon which th...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2126207

    authors: Peterzol A,Olivo A,Rigon L,Pani S,Dreossi D

    更新日期:2005-12-01 00:00:00

  • Chord-based image reconstruction in cone-beam CT with a curved detector.

    abstract::Modern computed tomography (CT) scanners use cone-beam configurations for increasing volume coverage, improving x-ray-tube utilization, and yielding isotropic spatial resolution. Recently, there have been significant developments in theory and algorithms for exact image reconstruction from cone-beam projections. In pa...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2337270

    authors: Zuo N,Xia D,Zou Y,Jiang T,Pan XC

    更新日期:2006-10-01 00:00:00

  • Kilovoltage stereotactic radiosurgery for age-related macular degeneration: assessment of optic nerve dose and patient effective dose.

    abstract::Age-related macular degeneration (AMD) is a leading cause for vision loss for people over the age of 65 in the United States and a major health problem worldwide. Research for new treatments of the wet form of the disease using kilovoltage stereotactic radiosurgery is currently underway at Oraya Therapeutics, Inc. In ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3168554

    authors: Hanlon J,Lee C,Chell E,Gertner M,Hansen S,Howell RW,Bolch WE

    更新日期:2009-08-01 00:00:00

  • Normalized dose data for upper gastrointestinal tract contrast studies performed to infants.

    abstract::The aim of the current study was to (a) provide normalized dose data for the estimation of the radiation dose from upper gastrointestinal tract contrast (UGIC) studies carried out to infants and (b) estimate the average patient dose and risks associated with radiation from UGIC examinations performed in our institutio...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2181297

    authors: Damilakis J,Stratakis J,Raissaki M,Perisinakis K,Kourbetis N,Gourtsoyiannis N

    更新日期:2006-04-01 00:00:00

  • SU-E-T-145: MRI Gel Dosimetry Applied to Dose Profile Determination for 50kV X-Ray Tube.

    abstract:PURPOSE:The aim of this study was to use MRI gel dosimetry to determine the dose profile of 50kV MAGNUM® X-ray tube, MOXTEK Inc., in order to calibrate small solid dosimeters of alanine, tooth enamel and LiF-TLDs, commonly used in clinical quality assurance and datation dosimetry. METHODS:MAGIC-f polymer gel was kept ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735203

    authors: Schwarcke M,Marques T,Nicolucci P,Filho OB

    更新日期:2012-06-01 00:00:00

  • Correcting TG 119 confidence limits.

    abstract:PURPOSE:Task Group 119 (TG-119) has been adopted for evaluating the adequacy of intensity-modulated radiation therapy (IMRT) commissioning and for establishing patient-specific IMRT quality assurance (QA) passing criteria in clinical practice. TG-119 establishes 95% confidence limits (CLs), which help clinics identify ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12759

    authors: Kearney V,Solberg T,Jensen S,Cheung J,Chuang C,Valdes G

    更新日期:2018-03-01 00:00:00

  • Quantitative study of focused ultrasound enhanced doxorubicin delivery to prostate tumor in vivo with MRI guidance.

    abstract:PURPOSE:The purpose of this study was to investigate the potential of MR-guided pulsed focused ultrasound (pFUS) for the enhancement of drug uptake in prostate tumors in vivo using doxorubicin (Dox). METHODS:An antitumor drug Dox, an orthotopic animal prostate tumor model using human prostate cancer, LNCaP cell line, ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4705346

    authors: Chen X,Cvetkovic D,Ma CM,Chen L

    更新日期:2012-05-01 00:00:00

  • The use of a priori information in the detection of mammographic microcalcifications to improve their classification.

    abstract::In this work, we present a calcification-detection scheme that automatically localizes calcifications in a previously detected cluster in order to generate the input for a cluster-classification scheme developed in the past. The calcification-detection scheme makes use of three pieces of a priori information: the loca...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1559884

    authors: Salfity MF,Nishikawa RM,Jiang Y,Papaioannou J

    更新日期:2003-05-01 00:00:00

  • Validation of GPUMCD for low-energy brachytherapy seed dosimetry.

    abstract:PURPOSE:To validate GPUMCD, a new package for fast Monte Carlo dose calculations based on the GPU (graphics processing unit), as a tool for low-energy single seed brachytherapy dosimetry for specific seed models. As the currently accepted method of dose calculation in low-energy brachytherapy computations relies on sev...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3598441

    authors: Hissoiny S,Ozell B,Després P,Carrier JF

    更新日期:2011-07-01 00:00:00

  • Evaluations of magnetic resonance imaging parameters with simple phantoms.

    abstract::Imaging parameters associated with a clinical magnetic resonance imaging (MRI) system, evaluated with the use of simple and inexpensive phantoms, are described in evaluation of a clinical MRI system. Images, obtained with a Diasonics 0.35-T MRI system using an elliptical whole-body radio frequency coil, are presented ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.595894

    authors: Brateman L,Jennings LW,Nunnally RL,Vaughan JT

    更新日期:1986-07-01 00:00:00

  • Quantitative assessment of bone mineral by photon scattering: accuracy and precision considerations.

    abstract::A method to determine the bone mineral density of the calcaneum has been reported earlier by our laboratory. In this method, the calcaneum is irradiated by a 60-keV photon beam from 241Am source and both the coherent and Compton scattered photons are detected by a high-purity Ge detector. The bone mineral density is d...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.595669

    authors: Shukla SS,Karellas A,Leichter I,Craven JD,Greenfield MA

    更新日期:1985-07-01 00:00:00

  • Regularized iterative weighted filtered backprojection for helical cone-beam CT.

    abstract::Contemporary reconstruction methods employed for clinical helical cone-beam computed tomography (CT) are analytical (noniterative) but mathematically nonexact, i.e., the reconstructed image contains so called cone-beam artifacts, especially for higher cone angles. Besides cone artifacts, these methods also suffer from...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2966353

    authors: Sunnegårdh J,Danielsson PE

    更新日期:2008-09-01 00:00:00

  • Technical Note: Comparison of megavoltage, dual-energy, and single-energy CT-based μ-maps for a four-channel breast coil in PET/MRI.

    abstract:PURPOSE:The purpose of this study was to describe and evaluate methods for calculating a megavoltage computed tomography (MVCT)-derived MR hardware attenuation map (μ-map) and dual-energy CT (DECT) for 511 keV photons. METHODS:Phantom measurements were acquired on a whole-body hybrid PET/MRI system, using a four-chann...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12407

    authors: Patrick JC,Terry Thompson R,So A,Butler J,Faul D,Stodilka RZ,Yartsev S,Prato FS,Gaede S

    更新日期:2017-09-01 00:00:00

  • A novel approach to evaluate spatial resolution of MRI clinical images for optimization and standardization of breast screening protocols.

    abstract:PURPOSE:Stringent quality assurance is required in MRI breast screening to ensure that different scanners and imaging protocols reach similar diagnostic performance. The authors propose a methodology, based on power spectrum analysis (PSA), to evaluate spatial resolution in clinical images. To demonstrate this approach...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4966704

    authors: Borri M,Scurr ED,Richardson C,Usher M,Leach MO,Schmidt MA

    更新日期:2016-12-01 00:00:00

  • Harmonic phase angle as a concentration-independent measure of nanoparticle dynamics.

    abstract:PURPOSE:The harmonic spectrum of magnetic nanoparticles contains valuable information about the quantity and environment of the particles. Harmonic amplitudes have been used to produce quantitative images and ratios of these amplitudes have been used to monitor changes in the particle environment. Harmonic phase angles...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3426294

    authors: Rauwerdink AM,Weaver JB

    更新日期:2010-06-01 00:00:00

  • Poster - Thurs Eve-38: CT Imaging in high dose rate brachytherapy for treatment of cervical cancer: Estimation of dose to bowel.

    abstract::Treatment of cervical cancer often involves intracavitary high dose rate (HDR) brachytherapy. Dose delivered to the bladder and rectum are typically estimated using the ICRU reference points. Dose to the sigmoid and small bowel are not estimated, yet these organs typically exhibit significant complication rates. The o...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2965957

    authors: Lekx-Toniolo KS,Hunter R,Patel M,Voruganti S,Johanson C,Dhamanaskar K,Farrell T

    更新日期:2008-07-01 00:00:00