Spectroscopic studies of cutaneous photosensitizing agents--XIV. The spin trapping of free radicals formed during the photolysis of halogenated salicylanilide antibacterial agents.

abstract：:Leaf discs, enclosed in a photoacoustic (PA) chamber, generate two types of PA gas-uptake signals under certain conditions. Type I is manifested by a severe signal decrease that develops slowly under very low-light intensity and often reaches negative values. It is partially reversed by low-intensity far-red light. Ty...

journal_title：Photochemistry and photobiology

authors： Malkin S,Havaux M

更新日期：2001-10-01 00:00:00

abstract：:The assessment model for ultraviolet radiation and risk "AMOUR" is applied to output from two chemistry-climate models (CCMs). Results from the UK Chemistry and Aerosols CCM are used to quantify the worldwide skin cancer risk avoided by the Montreal Protocol and its amendments: by the year 2030, two million cases of s...

journal_title：Photochemistry and photobiology

authors： van Dijk A,Slaper H,den Outer PN,Morgenstern O,Braesicke P,Pyle JA,Garny H,Stenke A,Dameris M,Kazantzidis A,Tourpali K,Bais AF

更新日期：2013-01-01 00:00:00

abstract：:Photosensitized inhibition of mitochondrial succinoxidase by hypericin was measured in vitro and found to be drug-dose, light-dose, and wavelength dependent. Singlet oxygen generation, monitored using the singlet oxygen trap tetramethylethylene, and oxygen consumption in isolated mitochondria sensitized by hypericin w...

journal_title：Photochemistry and photobiology

authors： Thomas C,MacGill RS,Miller GC,Pardini RS

更新日期：1992-01-01 00:00:00

abstract：:We have compared the distributions of two stable UV photoproducts in nucleosome core DNA at the single-nucleotide level using a T4 polymerase-exonuclease mapping procedure. The distribution of pyrimidine-pyrimidone (6-4) dimers was uncovered by reversing the major UV photo-product, cis-syn cyclobutane pyrimidine dimer...

journal_title：Photochemistry and photobiology

authors： Gale JM,Smerdon MJ

更新日期：1990-04-01 00:00:00

abstract：:We have previously demonstrated the ability of UVC (254 nm) radiation to induce asynchronous polyoma replication in rat fibroblast cells (H3 line) that contain an integrated copy of polyoma virus. In the present study we show that general purpose lamps can induce polyoma replication in these cells as well. The amount ...

journal_title：Photochemistry and photobiology

authors： Rutberg SE,Ronai Z

更新日期：1993-08-01 00:00:00

abstract：:Herein, we present a study of the pharmacokinetics and biodistribution of a butadiyne-linked conjugated porphyrin dimer (Oxdime) designed to have high near-infrared (NIR) 2-photon absorption cross-section for photodynamic therapy (PDT). Changes in biodistribution over time were monitored in mice carrying B16-F10 melan...

journal_title：Photochemistry and photobiology

authors： Khurana M,Ulrich S,Kim A,Moriyama Y,Netchev G,Akens MK,Anderson HL,Wilson BC

更新日期：2012-11-01 00:00:00

abstract：:A new water-soluble porphyrin derivative, 2,4-bis(1-decyloxyethyl)-deuteroporphyrinyl-6,7-bisaspart ic acid (C10-DP), and its metal complexes (Ga, I(n), Zn, Mn, Cu, Ni and Fe) were examined for their physicochemical properties (absorption, fluorescence, triplet lifetime and partition coefficient) and photocytotoxicity...

journal_title：Photochemistry and photobiology

authors： Ando T,Irie K,Koshimizu K,Takemura T,Nishino H,Iwashima A,Takeda N,Nakajima S,Sakata I

更新日期：1993-04-01 00:00:00

abstract：:The aim of this investigation is the evaluation of DNA interaction of with tetraruthenated porphyrin (TRP) and of DNA damage in the presence of light. Direct-fluorescence and electronic absorption measurements after incubation of DNA with TRP indicate strong binding between pBR322 DNA or calf thymus DNA with the modif...

journal_title：Photochemistry and photobiology

authors： Onuki J,Ribas AV,Medeiros MH,Araki K,Toma HE,Catalani LH,Di Mascio P

更新日期：1996-03-01 00:00:00

abstract：:Normal hematopoietic progenitor cells from 129S6/SvEv mice are substantially less sensitive to Merocyanine 540 (MC540)-mediated photodynamic therapy (PDT) than hematopoietic progenitors from sex- and age-matched C57BL/6 mice. When exposed to a combination of MC540 and light commonly used for the extracorporeal purging...

journal_title：Photochemistry and photobiology

authors： Tsujino I,Sieber F

更新日期：2000-12-01 00:00:00

abstract：:The ciliate Stentor coeruleus exhibits photodispersal, that is, these cells swim away from light sources and collect in dimly lighted areas. We imaged and reconstructed the tracks of 48 Stentor to determine which swimming behaviors produced their photodispersal. We observed that their photodispersal is not due to a ch...

journal_title：Photochemistry and photobiology

authors： Menzies E,Das N,Wood DC

更新日期：2004-11-01 00:00:00

abstract：:We previously reported that Shewanella oneidensis MR-1 is extremely sensitive to natural solar radiation (NSR). Here we analyzed the global transcriptional profile of MR-1 during a 1-h recovering period after exposure to ambient solar light at a dose that yields about 20% survival rate on a Luria-Bertani (LB) plate. W...

journal_title：Photochemistry and photobiology

authors： Qiu X,Tiedje JM,Sundin GW

更新日期：2005-11-01 00:00:00

abstract：:The interaction with amino acids of the excited states of the N-oxide resazurin and its deoxygenation product resorufin, has been studied in aqueous solution at pH 7.5. Steady-state and time-resolved studies show that the fluorescence is quenched by amino acids. Complexation of the dyes in the ground state with aromat...

journal_title：Photochemistry and photobiology

authors： Villegas ML,Bertolotti SG,Previtali CM,Encinas MV

更新日期：2005-07-01 00:00:00

abstract：:Activation of expression of the heme oxygenase (HO) gene appears to be involved in a cellular defense system in mammalian cells. We now demonstrate that while HO-1 mRNA levels are strongly inducible in dermal fibroblasts they are barely inducible in human epidermal keratinocytes following oxidative stress (UVA radiati...

journal_title：Photochemistry and photobiology

authors： Applegate LA,Noël A,Vile G,Frenk E,Tyrrell RM

更新日期：1995-03-01 00:00:00

abstract：:Exposure to ultraviolet radiation results in increased levels of intradermal cis-urocanic acid (cUCA) and alters cutaneous immunity by interfering with processing and presentation of antigen by Langerhans cells. Reports on effects of systemic immunotoxicity with 30 day cUCA exposure in laboratory rodents include thymi...

journal_title：Photochemistry and photobiology

authors： Prater MR,Gogal RM Jr,De Fabo EC,Longstreth J,Holladay SD

更新日期：2003-04-01 00:00:00

abstract：:In the vertebrate retina, rods mediate twilight vision and cones mediate daylight vision. Their photoresponse characteristics are different. The light-sensitivity of a cone is 10(2)-10(3) times lower than that of a rod. In addition, the photoresponse time course is much faster in cones. The mechanism characterizing co...

journal_title：Photochemistry and photobiology

authors： Tachibanaki S,Shimauchi-Matsukawa Y,Arinobu D,Kawamura S

更新日期：2007-01-01 00:00:00

abstract：:We have been able to identify a blue fluorophore from the low-molecular weight soluble fraction of human adult nondiabetic brunescent cataract lenses as xanthurenic acid 8-O-beta-D-glucoside (XA8OG) (excitation = 338 nm and emission = 440 nm). To determine the role of this fluorophore in the lens, we have examined its...

journal_title：Photochemistry and photobiology

authors： Thiagarajan G,Shirao E,Ando K,Inoue A,Balasubramanian D

更新日期：2002-09-01 00:00:00

abstract：:Phthalocyanine 4 (Pc 4) is a promising photosensitizer currently in clinical trials. Photobiological responses to Pc 4 photodynamic therapy (Pc 4-PDT) have been characterized extensively, but relatively little has been done to evaluate dose metrics for this sensitizer. We describe an irradiation-induced increase in fl...

journal_title：Photochemistry and photobiology

authors： Wang KK,Wilson JD,Kenney ME,Mitra S,Foster TH

更新日期：2007-09-01 00:00:00

abstract：:alpha-Terthienyl photosensitizes single strand breaks in pBR322 DNA. Almost identical results were observed under oxygen and under argon. In the presence of oxygen, this DNA nicking was enhanced by histidine and was not affected by superoxide dismutase, catalase, or the antioxidant BHT. Although chemical damage to DNA...

journal_title：Photochemistry and photobiology

authors： Wang TP,Kagan J,Tuveson RW,Wang GR

更新日期：1991-04-01 00:00:00

abstract：:The Escherichia coli protein YcgF contains a photosensory flavin adenine dinucleotide (FAD)-binding BLUF domain covalently linked to an EAL domain, which is predicted to have cyclic-di-guanosine monophosphate (GMP) phosphodiesterase activity. We have cloned, overexpressed and purified this protein, which we refer to a...

journal_title：Photochemistry and photobiology

authors： Rajagopal S,Key JM,Purcell EB,Boerema DJ,Moffat K

更新日期：2004-11-01 00:00:00

abstract：:The photochemistry of Ru(bpy)(3)+2 in the presence of amines was investigated in water by laser flash photolysis. N,N'-Dimethylaniline and p-phenylenediamine quench the luminescent metal to ligand charge transfer (MLCT) excited state of the complex by an electron transfer reaction that produces the semireduced form Ru...

journal_title：Photochemistry and photobiology

authors： Rivarola CR,Bertolotti SG,Previtali CM

更新日期：2006-01-01 00:00:00

abstract：:The interaction of photodynamic therapy (PDT) with 5-aminolevulinic acid (ALA) and hyperthermia is not well understood. In the present study, significant enhancement of tumor damage was observed after simultaneous application of ALA-PDT and IR-induced hyperthermia using a broad-band incoherent light source. One hour a...

journal_title：Photochemistry and photobiology

authors： Orenstein A,Kostenich G,Kopolovic Y,Babushkina T,Malik Z

更新日期：1999-06-01 00:00:00

abstract：:Comparative study of 13,15-[N-(2-hydroxyethyl)]cycloimide chlorin p6 (2), 13,15-(N-acetoxy)cycloimide chlorin p6 (3), 13,15-(N-hydroxy)cycloimide chlorin p6 methyl ester (4) and 13,15-(N-methoxy)cycloimide chlorin p6 methyl ester (5) together with the previously investigated 13,15-[N-(3-hydroxypropyl)]cycloimide chlor...

journal_title：Photochemistry and photobiology

authors： Feofanov A,Sharonov G,Grichine A,Karmakova T,Pljutinskaya A,Lebedeva V,Ruziyev R,Yakubovskaya R,Mironov A,Refregier M,Maurizot JC,Vigny P

更新日期：2004-02-01 00:00:00

abstract：:The wavelength dependence of an ultraviolet irradiation of the DNA substrate for a human endonuclease was determined. Sites of DNA incision for all UVB and UVC wavelengths examined were at cytosines which were neither cyclobutane pyrimidine dimers nor 6-4'-(pyrimidin-2-one)pyrimidines. The optimal wavelengths for form...

journal_title：Photochemistry and photobiology

authors： Gallagher PE,Weiss RB,Brent TP,Duker NJ

更新日期：1989-03-01 00:00:00

abstract：:The in vivo pharmacokinetics of protoporphyrin IX (PpIX) after administration of 5-aminolevulinic acid (ALA) cannot be described accurately by mathematical models using first-order rate processes. We have replaced first-order reaction rates by dose-dependent (Michaelis-Menten [MM]) reaction rates in a mathematical com...

journal_title：Photochemistry and photobiology

authors： Aalders MC,van der Vange N,Star WM,Sterenborg HJ

更新日期：2001-08-01 00:00:00

abstract：:Structure-activity relationships have been widely reported for porphyrin and phthalocyanine photosensitizers, but not for phenothiazinium derivatives. Here, four phenothiazinium salts (methylene blue, toluidine blue O, 1,9-dimethyl methylene blue and the pentacyclic derivative DO15) were used to investigate how the ab...

journal_title：Photochemistry and photobiology

authors： Bacellar IO,Pavani C,Sales EM,Itri R,Wainwright M,Baptista MS

更新日期：2014-07-01 00:00:00

abstract：:UVR8 is the only known plant photoreceptor that mediates light responses to UV-B (280-315 nm) of the solar spectrum. UVR8 perceives a UV-B signal via light-induced dimer dissociation, which triggers a wide range of cellular responses involved in photomorphogenesis and photoprotection. Two recent crystal structures of ...

journal_title：Photochemistry and photobiology

authors： Yang X,Montano S,Ren Z

更新日期：2015-09-01 00:00:00

abstract：:Proteases like urokinase-type plasminogen activator (uPA) play an important role in tumor invasion. Cells derived from ultraviolet radiation (UVR)-induced corneal sarcomas of Monodelphis domestica produce relatively high levels of uPA compared to the untransformed keratocytes suggesting a mechanism for their invasiven...

journal_title：Photochemistry and photobiology

authors： Green WB,McGuire PG,Miska KB,Kusewitt DF

更新日期：2001-03-01 00:00:00

abstract：:We conducted a thermovisual comparison of mean hand surface temperature changes upon local heating with two different IR sources. Sixty-six patients with rheumatoid arthritis (47 women and 19 men; average age, 56.1 ± 8.6 years) were subjected to topical heat therapy for one hand with either the standard IR radiator (S...

journal_title：Photochemistry and photobiology

authors： Rutkowski R,Straburzyńska-Lupa A,Korman P,Romanowski W,Gizińska M

更新日期：2011-11-01 00:00:00

abstract：:Unlike the enchanting yellow-green flashes of light produced on warm summer evenings by Photinus pyralis, the most common firefly species in North America, the orange lights of Photinus scintillans are infrequently observed. These Photinus species, and likely all bioluminescent beetles, use the same substrates beetle ...

journal_title：Photochemistry and photobiology

authors： Branchini BR,Southworth TL,Fontaine DM,Murtiashaw MH,McGurk A,Talukder MH,Qureshi R,Yetil D,Sundlov JA,Gulick AM

更新日期：2017-03-01 00:00:00

abstract：:Although the first reactive oxygen species (ROS) formed during irradiation of photosensitized cells is almost invariably singlet molecular oxygen (1O2), other ROS have been implicated in the phototoxic effects of photodynamic therapy (PDT). Among these are superoxide anion radical (*O2(-)), hydrogen peroxide (H2O2) an...

journal_title：Photochemistry and photobiology

authors： Price M,Terlecky SR,Kessel D

更新日期：2009-11-01 00:00:00