Wavelength dependence of DNA incision by a human ultraviolet endonuclease.

abstract：:DNA UVB dosimeters, consisting of minidots of dried bacteriophage DNA placed on a UV-transparent polymer film, were analyzed by polymerase chain reactions (PCR). Ultraviolet-B dosimetry obtained with amplification of phage lambda DNA of segments of 1.08 kilobase pairs (kbp) and 2.24 kbp was compared with that obtained...

journal_title：Photochemistry and photobiology

authors： Yoshida H,Regan JD

更新日期：1997-11-01 00:00:00

abstract：:Photoproducts in double-stranded DNA induced by 193 nm radiation have been investigated. Double-stranded, supercoiled pBR322 DNA in buffered aqueous solution was exposed to varying fluences of 193 nm radiation from an ArF excimer laser. The quantum yields for formation of cyclobutylpyrimidine dimers, frank strand brea...

journal_title：Photochemistry and photobiology

authors： Kochevar IE,Buckley LA

更新日期：1990-05-01 00:00:00

abstract：:The photochemistry of caged compounds of the o-nitrobenzyl type has been investigated thoroughly in the past. However, even recently new side reactions have been discovered. Earlier, we reported [Bley, F., K. Schaper, and H. Görner (2008), Photochem. Photobiol.84 162-171] that we found long-lived triplet states which ...

journal_title：Photochemistry and photobiology

authors： Schaper K,Etinski M,Fleig T

更新日期：2009-09-01 00:00:00

abstract：:Use of near infrared instead of visible light would markedly improve tissue penetration, making larger tumors candidates for photochemotherapy. Because common photesensitizers exhibit virtually no absorption in this wavelength region, conditions are required where the simultaneous action of two photons is possible. He...

journal_title：Photochemistry and photobiology

authors： Lenz P

更新日期：1995-08-01 00:00:00

abstract：:The two-photon photolysis of liquid CCl4 with 25 ps pulses of 266 nm light has been studied and compared with similar studies with high energy radiation. Both neutral and ionic species are produced from excited states and ionization. The emphasis of the study is on the ionic processes, while some data related to excit...

journal_title：Photochemistry and photobiology

authors： Zhang G,Thomas JK

更新日期：2006-01-01 00:00:00

abstract：:Pheophorbide a-induced photo-oxidation, in vitro, of cytochrome c oxidase and cytochrome c results in irreversible modifications to both protein components. Photo-oxidation of cytochrome c, as exhibited by change in its heme oxidation state, displays exponential kinetics and is detected with a lag period. Both the pho...

journal_title：Photochemistry and photobiology

authors： Chernomorsky S,Wong C,Poretz RD

更新日期：1992-02-01 00:00:00

abstract：:Persister bacteria tolerate bactericidal antibiotics due to transient and reversible phenotypic changes. As these bacteria can limit the effectiveness of antibiotics to eradicate certain infections, their elimination is a relevant issue. Photodynamic therapy seems suitable for this purpose, but phenotypic tolerance to...

journal_title：Photochemistry and photobiology

authors： Oppezzo OJ,Forte Giacobone AF

更新日期：2018-01-01 00:00:00

abstract：:Extracellular pH was measured continuously and noninvasively in hairless mice using a transcutaneous spectrofluorometric technique and a fluorescent pH probe, bis-carboxyethyl carboxyfluorescein (BCECF). The acid form of BCECF was injected intravenously. An optical fiber system excited the fluorescent probe at 450 and...

journal_title：Photochemistry and photobiology

authors： Russell DA,Pottier RH,Valenzeno DP

更新日期：1994-03-01 00:00:00

abstract：:Because metallothionein (MT) is elevated and may be protective in UV-irradiated skin, we have studied the effects of UV and other agents on MT transcription using the sheep MT 1A promoter, linked to the beta-galactosidase gene and stably transfected into human cell lines. beta-galactosidase reporter activity was induc...

journal_title：Photochemistry and photobiology

authors： Hansen C,Ablett E,Green A,Sturm RA,Dunn IS,Fairlie DP,West ML,Parsons PG

更新日期：1997-03-01 00:00:00

abstract：:Quantum yields for the formation of superoxide ions, O2-., and singlet oxygen, 1O2, were determined during the photolyses of gilvocarcin M (GM) in air-saturated dry dimethylsulfoxide (DMSO) and in 45:55 (vol/vol) DMSO-water mixtures. The quantum yield for the photoreduction of methyl viologen by GM in nitrogen-saturat...

journal_title：Photochemistry and photobiology

authors： Alegría AE,Zayas L,Guevara N

更新日期：1995-09-01 00:00:00

abstract：:Photodynamic therapy (PDT) is a way of treating malignant tumors and hyperproliferative diseases. It is based on the use of photosensitizer, herein the chlorophyll a (chl a), and a light of an appropriate wavelength. The interaction of the photosensitizer (PS) with the light produces reactive oxygen species (ROS), pow...

journal_title：Photochemistry and photobiology

authors： Cellamare BM,Fini P,Agostiano A,Sortino S,Cosma P

更新日期：2013-03-01 00:00:00

abstract：:A solution of iodouracil (0.2 mg/mL) and KI (0.1 M) in 0.23 M borate buffer (pH 7) forms triiodide upon exposure to UVB. In the presence of thyodene, the blue starch-iodine complex is formed, the intensity of which is proportional to the amount of UVB exposure. Studies were conducted using either a sunlamp or solar ir...

journal_title：Photochemistry and photobiology

authors： Rahn R,Lee MA

更新日期：1998-08-01 00:00:00

abstract：:This paper reviews briefly the evidence for an association between various measures of UV radiation (UVR) exposure and the development of cancer. Issues such as data quality, study design, measurement variation, comparability of studies, and quantification of UV exposure in relation to skin cancer are discussed. A ran...

journal_title：Photochemistry and photobiology

authors： Berwick M,Kesler D

更新日期：2005-11-01 00:00:00

abstract：:The fluorescent pH probe carboxy-seminaphtorhodafluor-1 (C-Snarf-1) has been used for laser microspectro-fluorometric assays of intracellular pH in 3T3 mouse fibroblasts treated with hypocrellin A. These results are compared to those previously obtained with the structurally related hydroxylated polycyclic quinone, hy...

journal_title：Photochemistry and photobiology

authors： Chaloupka R,Sureau F,Kocisova E,Petrich JW

更新日期：1998-07-01 00:00:00

abstract：:The size of excision repair patches corresponding to excision of (6-4) pyrimidine-pyrimidone photoproducts and (5-5, 6-6) cyclobutane dimers have been independently determined by using bromodeoxyuridine substitution and density increases in isopycnic gradients of small DNA fragments. The two classes of photoproducts w...

journal_title：Photochemistry and photobiology

authors： Cleaver JE,Jen J,Charles WC,Mitchell DL

更新日期：1991-09-01 00:00:00

abstract：:Although the first reactive oxygen species (ROS) formed during irradiation of photosensitized cells is almost invariably singlet molecular oxygen (1O2), other ROS have been implicated in the phototoxic effects of photodynamic therapy (PDT). Among these are superoxide anion radical (*O2(-)), hydrogen peroxide (H2O2) an...

journal_title：Photochemistry and photobiology

authors： Price M,Terlecky SR,Kessel D

更新日期：2009-11-01 00:00:00

abstract：:The azide ion is a strong physical quencher of singlet molecular oxygen (1O2) and is frequently employed to show involvement of 1O2 in oxidation processes. Rate constants (k(q)) for the quenching of 1O2 by azide are routinely used as standards to calculate k(q) values for quenching by other substrates. We have measure...

journal_title：Photochemistry and photobiology

authors： Li MY,Cline CS,Koker EB,Carmichael HH,Chignell CF,Bilski P

更新日期：2001-12-01 00:00:00

abstract：:Neutral filter elution at pH 7.2 and 9.6 was used to measure the induction of DNA lesions in human P3 teratocarcinoma cells by monochromatic 254-, 270-, 313-, 334-, 365-, and 405-nm radiation and by 60 gamma rays. In this assay DNA double-strand breaks (dsb) increase the rate of elution of DNA from cell lysates on a f...

journal_title：Photochemistry and photobiology

authors： Peak JG,Peak MJ

更新日期：1990-08-01 00:00:00

abstract：:Uveal melanoma is the most frequent intraocular cancer and the second most common form of melanoma. It metastasizes in half of the patients and the prognostic is poor. Although ultraviolet (UV) radiation is a proven risk factor for skin melanoma, the role of UV light in the etiology of uveal melanoma is still contradi...

journal_title：Photochemistry and photobiology

authors： Mallet JD,Gendron SP,Drigeard Desgarnier MC,Rochette PJ

更新日期：2014-01-01 00:00:00

abstract：:Excessive sun exposure can cause sunburn, suntan, skin photoaging, and even skin cancer. Skin photoaging conflicts with the human pursuit of a young and beautiful appearance. Some research data indicate that the incidence of skin cancer in the Chinese has been increasing, although it remains lower than in whites. To e...

journal_title：Photochemistry and photobiology

authors： Wan M,Hu R,Li Y,Wang Y,Xie X,Yue P,Guan L,Lai W

更新日期：2016-09-01 00:00:00

abstract：:The efficacy of photodynamic therapy (PDT) depends upon the amount of photosensitizer accumulated in the malignant tissues. Radachlorin is a popular photosensitizer used in photodynamic therapy to treat various types of cancer. In this study, we have studied the main organelles responsible for the accumulation of rada...

journal_title：Photochemistry and photobiology

authors： Biswas R,Moon JH,Ahn JC

更新日期：2014-09-01 00:00:00

abstract：:In this study, we aimed to analyze the effects of low-level laser therapy (LLLT; 660 nm) on levels of protein expression of inflammatory mediators after cutting Achilles tendon of rats. Thirty Wistar male rats underwent partial incisions of the left Achilles tendon, and were divided into three groups of 10 animals acc...

journal_title：Photochemistry and photobiology

authors： Laraia EM,Silva IS,Pereira DM,dos Reis FA,Albertini R,de Almeida P,Leal Junior EC,de Tarso Camillo de Carvalho P

更新日期：2012-11-01 00:00:00

abstract：:Sulfur-substituted nucleobases (a.k.a., thiobases) are among the world's leading prescriptions for chemotherapy and immunosuppression. Long-term treatment with azathioprine, 6-mercaptopurine and 6-thioguanine has been correlated with the photoinduced formation of carcinomas. Establishing an in-depth understanding of t...

journal_title：Photochemistry and photobiology

authors： Ashwood B,Pollum M,Crespo-Hernández CE

更新日期：2019-01-01 00:00:00

abstract：:Structure-activity relationships have been widely reported for porphyrin and phthalocyanine photosensitizers, but not for phenothiazinium derivatives. Here, four phenothiazinium salts (methylene blue, toluidine blue O, 1,9-dimethyl methylene blue and the pentacyclic derivative DO15) were used to investigate how the ab...

journal_title：Photochemistry and photobiology

authors： Bacellar IO,Pavani C,Sales EM,Itri R,Wainwright M,Baptista MS

更新日期：2014-07-01 00:00:00

abstract：:Evanescent wave illumination with total internal reflection is often used to provide excitation near a quartz-water interface. We now show that evanescent illumination at one wavelength and incident angle, coupled with light quenching at a second wavelength and incident angle, can be used for selective excitation of f...

journal_title：Photochemistry and photobiology

authors： Lakowicz JR,Gryczynski Z,Gryczynski I

更新日期：1996-10-01 00:00:00

abstract：:More scheduled outdoor stay is increasingly advocated for school children. This study measured 2(nd) , 5(th) and 8(th) graders' erythemal UV-exposure in September, March and May at four Swedish schools. We related those exposures, as fractions of total available ambient radiation, to the schools outdoor environments d...

journal_title：Photochemistry and photobiology

authors： Pagels P,Wester U,Söderström M,Lindelöf B,Boldemann C

更新日期：2016-01-01 00:00:00

abstract：:Latia neritoides is a small limpet-like snail that produces a bright green bioluminescence (BL) via a unique light-emitting system. The process, mechanism, and even light emitter of its light emission remain unknown, although this BL has been known for decades. Unlike the other BL systems, neither the luciferin (Luc) ...

journal_title：Photochemistry and photobiology

authors： Yu M,Ohmiya Y,Naumov P,Liu YJ

更新日期：2018-05-01 00:00:00

abstract：:The capacity of some linear and angular furocoumarins to induce DNA-protein cross-links by UVA (320-400 nm) irradiation has been evaluated in Chinese hamster ovary cells. Two linear furocoumarins, psoralen and 8-methoxypsoralen appeared to be capable of inducing DNA-protein cross-links to a noticeable extent. 4'-Methy...

journal_title：Photochemistry and photobiology

authors： Bordin F,Carlassare F,Busulini L,Baccichetti F

更新日期：1993-07-01 00:00:00

abstract：:The seminal discovery by James Cleaver of defective DNA repair in xeroderma pigmentosum (XP) opened up an ever-expanding field of DNA repair-related disorders. In addition, it put XP on the map and has led to improved diagnosis, care and management of affected patients. In the United Kingdom, we recently established a...

journal_title：Photochemistry and photobiology

authors： Lehmann AR

更新日期：2015-03-01 00:00:00

abstract：:Melatonin (N-acetyl-5-methoxytryptamine) is a naturally occurring hormone with a structural resemblance to tryptophan. Its fluorescence is solvent dependent and strongly quenched in the presence of oxygen. Fluorescence quenching in aqueous and organic solutions have been studied in the presence of different quenchers....

journal_title：Photochemistry and photobiology

authors： Rath MC,Mahal HS,Mukherjee T

更新日期：1999-03-01 00:00:00