Abstract:
BACKGROUND:Ebola viral disease (EVD) epidemic need to be contained through means which include vaccination of susceptible population. Vaccination has eradicated major killer diseases. OBJECTIVE:The study determined the health workers willingness to participate in EVD vaccine clinical trials and receive EVD vaccine. MATERIALS AND METHODS:A descriptive cross-sectional study design involving 370 consenting health workers of Obafemi Awolowo University, Ile-Ife that completed a self administered semi-structured questionnaire. Data analysed using descriptive and inferential statistics. RESULTS:Mean age was 34.4±8.6years (range, 19-60years). Most were females (60.3%), and had worked <10years (74.3%). The health workers were mostly medical doctors (22.7%) and nurses (52.4%). EVD awareness (84.9%) was high among respondents with radio (37.2%) as major source of information. A higher proportion of respondents willing to participate in clinical trials were willing to receive vaccine (93% vs. 68%, p=0.0001). The significant variables associated with willingness to participate in EVD vaccine trials include being male [AOR 1.58, 95%CI 1.04-2.40, p=0.033], medical doctor [AOR 2.28, 95%CI 1.31-3.96, p=0.003] and having safe vaccine [AOR 2.10, 95% 1.58-3.98, p=0.0001] while the significant variable associated with willingness to receive EVD vaccine was vaccine safety [AOR 3.19, 95%CI 2.13-6.03, p=0.029]. CONCLUSION:Male gender, medical doctor and vaccine safety determine willingness to participate in Ebola vaccine trials while vaccine safety determines willingness to receive vaccine when ready. Researchers should ensure gender equality and vaccine safety in vaccine trials.
journal_name
Vaccinejournal_title
Vaccineauthors
Olowookere SA,Abioye-Kuteyi EA,Adekanle Odoi
10.1016/j.vaccine.2016.10.004subject
Has Abstractpub_date
2016-11-11 00:00:00pages
5758-5761issue
47eissn
0264-410Xissn
1873-2518pii
S0264-410X(16)30900-8journal_volume
34pub_type
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