Abstract：
:Safety of and humoral immune response to the anti-influenza vaccine in coronary artery disease (CAD) patients were evaluated. The trivalent vaccine was administered to 137 eligible CAD patients and 67 age- and sex-matched healthy individuals. Antibody (Ab) titers were measured before and 1 month after vaccination. CAD and HC groups were not significantly different in serologic response and magnitude of change in antibody titers against each of the vaccine antigens. In multivariate analyses, regular exercise and using multivitamin supplements were independently associated with better antibody response among CAD patients. There were no major cardiac or general adverse effects. Influenza vaccine was found safe in CAD patients and antibody responses were similar to HCs.
journal_name
Vaccinejournal_title
Vaccineauthors
Keshtkar-Jahromi M,Vakili H,Rahnavardi M,Gholamin S,Razavi SM,Eskandari A,Sadeghi R,Vatan-Pour H,Keshtkar-Jahromi M,Haghighat B,Ghaffaripour M,Mokhtari-Azad Tdoi
10.1016/j.vaccine.2009.09.108subject
Has Abstractpub_date
2009-12-10 00:00:00pages
110-3issue
1eissn
0264-410Xissn
1873-2518pii
S0264-410X(09)01468-6journal_volume
28pub_type
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