Abstract：
:Infection of rubella virus at the early stages of pregnancy in women who are not immune to rubella often induces congenital anomalies in infants, namely congenital rubella syndrome (CRS). This paper is the first comprehensive report of CRS cases in Japan, compiled from a questionnaire to major hospitals, reports to journals and academic meetings, and cases for virus/virus genome verification submitted to the National Institute of Infectious Diseases. CRS incidence in Japan was determined to be 0.2-8.1 cases/100,000 live births per year in epidemic years and 0.1-0.7 in non-epidemic years, respectively. In the last 4 years, the number of CRS cases remarkably decreased to one-three cases per year. This decrease is thought to be because the immunization law was revised in 1994 for changing the focus of rubella immunization from junior high school girls to infants of both sexes.
journal_name
Vaccinejournal_title
Vaccineauthors
Katow Sdoi
10.1016/j.vaccine.2004.03.055subject
Has Abstractpub_date
2004-09-28 00:00:00pages
4084-91issue
29-30eissn
0264-410Xissn
1873-2518pii
S0264410X04003226journal_volume
22pub_type
杂志文章相关文献
VACCINE文献大全abstract：:The varied rates of protection induced by Mycobacterium bovis BCG vaccine against tuberculosis has been attributed to many factors such as genetic variability among BCG strains, rapid clearance of BCG in some populations, and different levels of previous exposure of vaccinated populations to environmental mycobacteria...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2011.12.044
更新日期：2012-02-01 00:00:00
abstract：:A choice-format, conjoint-analysis survey was developed and fielded to estimate how features of human papillomavirus (HPV) vaccines affect mothers' perceived benefit and stated vaccine uptake for daughters. Data were collected from a national sample of 307 U.S. mothers of girls aged 13-17 years who had not yet receive...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2009.12.024
更新日期：2010-02-17 00:00:00
abstract：:The development of live attenuated vaccines, allowing for the safe and effective immunisation at mucosal surfaces, is a strategy of great interest for vaccinologists. The main advantage of this approach over conventional parenteral vaccines is the induction of strong mucosal immune responses, allowing targeting of the...
journal_title：Vaccine
pub_type： 杂志文章,评审
doi：10.1016/j.vaccine.2003.12.033
更新日期：2004-06-23 00:00:00
abstract：:Dengue fever and dengue hemorrhagic fever are endemic throughout tropical and subtropical countries. Four serotypes of dengue viruses (DENV-1 to DENV-4), each with several genotypes including various subclades, are co-distributed in most endemic areas. Infection-neutralizing and -enhancing antibodies are believed to p...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2014.06.017
更新日期：2014-07-23 00:00:00
abstract：:Chikungunya virus is an emerging pathogen initially found in East Africa and currently spread into the Indian Ocean Islands, many regions of South East Asia, and in the Americas. No licensed vaccines against this eminent pathogen are available and thus intensive research in this field is a priority. This review presen...
journal_title：Vaccine
pub_type： 杂志文章,评审
doi：10.1016/j.vaccine.2015.05.104
更新日期：2015-07-17 00:00:00
abstract：:Vaccination strategies against Klebsiella pneumoniae have largely focussed on the polysaccharide capsule. However, the large number and high prevalence of individual capsular serotypes limits the widespread applicability of capsule-based vaccines. This study establishes that immunization with purified LPS can protect ...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2008.07.100
更新日期：2008-10-16 00:00:00
abstract：:The characterization of the cross-reactive, or heterologous, neutralizing antibody (NAb) responses developed during HIV-1-infection is relevant to the development of an HIV vaccine. Here we summarize our recently published study where we characterized the cross-reactive NAb responses in two cohorts of anti-retroviral ...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2009.07.085
更新日期：2010-05-26 00:00:00
abstract：:The immunotherapeutic properties of a new Pythium insidiosum-vaccine formulation (PIV), was evaluated in 18 horses and 6 dogs with proven pythiosis from different enzootic areas in the United States. All injected horses but one responded with a weak (=29 mm, n=3), a mild (30-90 mm, n=7) or a strong (=100 mm, n=7) infl...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/s0264-410x(03)00225-1
更新日期：2003-06-20 00:00:00
abstract：:In line with WHO objectives, the Lao Government is committed to eliminate measles by 2012. Yet from 1992 to 2007, the annual incidence of measles remained high while the vaccination coverage showed a wide diversity across provinces. A descriptive study was performed to determine factors affecting compliance with vacci...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2010.07.077
更新日期：2010-09-24 00:00:00
abstract：:Tattooing has been shown to be very efficient at inducing immunity by vaccination with DNA vaccines. In this study, we examined the usability of tattooing for delivery of peptide vaccines. We compared tattooing with subcutaneous (s.c.) needle injection using peptides derived from human papillomavirus type 16 (HPV16) p...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2009.03.073
更新日期：2009-06-02 00:00:00
abstract：:A post-marketing study was conducted in 26 paediatric practices in Germany to collect safety information on the virosomal adjuvanted influenza vaccine Inflexal V (in Germany marketed as Infectovac Flu). Children aged 6 months to 6 years received one or two doses. Adverse events were documented by parents/legal guardia...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2008.12.008
更新日期：2009-02-18 00:00:00
abstract：:In this investigation we have generated and defined the immunogenicity of two novel HIV/AIDS vaccine candidates based on the highly attenuated vaccinia virus strains, MVA and NYVAC, efficiently expressing in the same locus (TK) and under the same viral promoter the codon optimized HIV-1 genes encoding gp120 and Gag-Po...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2006.09.090
更新日期：2007-04-12 00:00:00
abstract：:The calculation of p(epitope) values, a sequence-based measure of antigenic distance between strains, was developed for human influenza. The potential to apply the p(epitope) value to equine influenza vaccine strain selection was assessed. There was a negative correlation between p(epitope) value and vaccine efficacy ...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2013.06.070
更新日期：2013-12-09 00:00:00
abstract：:Modified Vaccinia virus Ankara (MVA) is an attenuated strain of vaccinia virus that is being considered as a safer alternative to replicating vaccinia vaccine strains such as Dryvax(®) and ACAM2000. Its excellent safety profile and large genome also make it an attractive vector for the delivery of heterologous genes f...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2011.11.021
更新日期：2012-01-11 00:00:00
abstract：BACKGROUND:Disparities in vaccine-preventable disease (VPD) burden and immunisation coverage between migrants and refugees and their host populations have been described in numerous countries worldwide. Effective strategies are required to reduce the health disparities and immunisation inequities experienced by migrant...
journal_title：Vaccine
pub_type： 杂志文章,评审
doi：10.1016/j.vaccine.2020.09.054
更新日期：2020-10-27 00:00:00
abstract：:Preclinical vaccine efficacy studies are generally limited to certain read out parameters such as assessment of virus titers in swabs and organs, clinical signs, serum antibody titers, and pathological changes. These parameters are not always routinely applied and not always scheduled in a logical standardized way. We...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2012.10.008
更新日期：2012-12-07 00:00:00
abstract：:Forty-four adult patients with cutaneous leishmaniasis (CL) were enrolled in a randomized, double-blind, controlled, dose-escalating clinical trial and were randomly assigned to receive three injections of either the LEISH-F1+MPL-SE vaccine (consisting of 5, 10, or 20 μg recombinant Leishmania polyprotein LEISH-F1 ant...
journal_title：Vaccine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.vaccine.2010.07.063
更新日期：2010-09-14 00:00:00
abstract：:The schistosome integral membrane protein Sm/Sj23 was initially shown to induce protection in mice as a synthetic peptide vaccine and further, as a plasmid DNA vaccine to induce protection in mice, sheep and water buffalo. In this study we asked if we could induce protection against challenge infection in pigs against...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2004.04.031
更新日期：2004-11-15 00:00:00
abstract：:Vaccine effects of in vivo gene-vaccinated skin graft were evaluated against Toxoplasma gondii (T. gondii) infection. By using a gene gun, cDNA coding T. gondii SAG1 molecule was intracutaneously vaccinated into C57BL/6 (B6; a susceptible strain), BALB/c (a resistant strain) and (C57BL/6 x BALB/c) F1 (CBF1) mice, and ...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/s0264-410x(00)00366-2
更新日期：2001-02-28 00:00:00
abstract：:Two double-blind randomised controlled studies (phase I and I/II) were performed to assess for the first time the safety and immunogenicity of a recombinant subunit gp350 Epstein-Barr virus (EBV) vaccine in 148 healthy adult volunteers. All candidate vaccine formulations had a good safety profile and were well tolerat...
journal_title：Vaccine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.vaccine.2007.04.008
更新日期：2007-06-11 00:00:00
abstract：:The induction of oral tolerance against disease-inducing antigens has emerged as a feasible strategy to prevent immunopathologies. In this study, we investigated the effect of oral immunization with whole antigens of Leishmania amazonensis promastigotes (LaAg) on murine cutaneous leishmaniasis. We found that two oral ...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/s0264-410x(03)00427-4
更新日期：2003-09-08 00:00:00
abstract：:Epidemic influenza occurs annually throughout the world and is accompanied by excess morbidity and mortality. Increasing the antigen content and topical administration of vaccine are two strategies being explored to improve the immune responses to trivalent inactivated influenza vaccine (TIV). We conducted a randomize...
journal_title：Vaccine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.vaccine.2007.05.002
更新日期：2007-07-20 00:00:00
abstract：:EBA-175 protein is used as ligand in Plasmodium falciparum binding to erythrocytes. Evidence shows that conserved peptide 1815 from this protein having high red blood cell binding ability plays an important role in the invasion process. This peptide is neither immunogenic nor protective. Residues were substituted by a...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2004.08.052
更新日期：2005-02-18 00:00:00
abstract：:Japanese encephalitis (JE) is a fatal mosquito-borne disease that is vaccine-preventable. The natural infection rate is a critical factor for evaluations of the necessity for vaccination. Detection of antibodies to virus nonstructural (NS) proteins is a theoretical strategy to survey natural infections among populatio...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2009.09.064
更新日期：2009-11-23 00:00:00
abstract：:A number of challenges for developing a protective pre-pandemic influenza A vaccine exists including predicting the target influenza strain and designing the vaccine for an immunologically naïve population. Manufacturing and supply of the vaccine would also require implementing ways to increase coverage for the larges...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2017.07.107
更新日期：2017-09-12 00:00:00
abstract：:A method was developed for cultivation of the strain Shigella flexneri 2a 77 with two attenuated markers. It ensures the preservation of the initial properties of the strain. The regimen for control of dissolved oxygen level was optimized. It was established that yeast extract is a necessary component of the nutritive...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/0264-410x(87)90099-5
更新日期：1987-09-01 00:00:00
abstract：:We determined the immunogenicity of conjugated Haemophilus influenzae type b and pneumococcal vaccines by quantitative analysis of the antibody response in asplenic patients. To that end, we vaccinated 92 patients with a conjugated Hib vaccine and 54 received two doses of conjugated pneumococcal vaccine (PCV7), follow...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2010.11.034
更新日期：2011-01-17 00:00:00
abstract：:In many countries, foot and mouth disease (FMD) is controlled by vaccination and surveillance against non-capsid proteins (NCP); therefore vaccines are required not to induce antibodies against NCP. Vaccine purity is evaluated by repeated inoculation of naïve cattle, an expensive and time consuming protocol that raise...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2010.05.049
更新日期：2010-09-14 00:00:00
abstract：:This work demonstrates the presence of immune regulatory cells in the cervical lymph nodes draining Bacillus Calmette-Guérin (BCG) vaccinated site on the dorsum of the ear in guinea pigs. It is shown that whole cervical lymph node cells did not proliferate in vitro in the presence of soluble mycobacterial antigens (PP...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2020.10.009
更新日期：2020-11-10 00:00:00
abstract：:A growing number of people use the Internet to obtain health information, including information about vaccines. Websites that allow and promote interaction among users are an increasingly popular source of health information. Users of such so-called Web 2.0 applications (e.g. social media), while still in the minority...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2012.02.025
更新日期：2012-05-28 00:00:00
