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Introducing dengue vaccine: Implications for diagnosis in dengue vaccinated subjects.

Abstract：

:Diagnosis of dengue virus infections is complicated by preference for different diagnostic tests in different post onset days of illness and the presence of multiple serotypes leading to secondary and tertiary infections. The sensitivity of the most commonly employed diagnostic assays such as anti dengue IgM capture (MAC) ELISA and non structural protein (NS) 1 capture ELISA are lower in secondary and subsequent infections. Introduction of dengue vaccine in endemic regions will affect the way how dengue is diagnosed in vaccinated subjects. This viewpoint article discusses implications of introduction of dengue vaccine on the diagnosis of dengue infections in vaccinated subjects and the strategies that are needed to tackle the issue.

journal_name

Vaccine

journal_title

Vaccine

authors

Alagarasu K

doi

10.1016/j.vaccine.2016.04.070

subject

Has Abstract

pub_date

2016-05-27 00:00:00

pages

2759-61

issue

25

eissn

0264-410X

issn

1873-2518

pii

S0264-410X(16)30235-3

journal_volume

34

pub_type

杂志文章

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