Finding DNA Ends within a Haystack of Chromatin.

Abstract:

:Identifying DNA fragile sites is crucial to reveal hotspots of genomic rearrangements, yet their precise mapping has been a challenge. A new study in this issue of Molecular Cell (Canela et al., 2016) introduces a highly sensitive and accurate method to detect DNA breaks in vivo that can be adapted to various experimental and clinical settings.

journal_name

Mol Cell

journal_title

Molecular cell

authors

Banerjee U,Soutoglou E

doi

10.1016/j.molcel.2016.08.012

subject

Has Abstract

pub_date

2016-09-01 00:00:00

pages

726-8

issue

5

eissn

1097-2765

issn

1097-4164

pii

S1097-2765(16)30426-9

journal_volume

63

pub_type

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