Cyclic di-GMP in Streptomycetes: A New Conformation, New Binding Mode, New Receptor, and a New Mechanism to Control Cell Development.

Abstract:

:A recent paper by Gallagher et al. (2020) demonstrates that c-di-GMP controls spore formation in Streptomyces venezuelae through sequestering the sporulation sigma factor σWhiG and presents the crystal structure of a ternary complex between c-di-GMP, σWhiG, and its anti-sigma factor, RsiG.

journal_name

Mol Cell

journal_title

Molecular cell

authors

Chou SH,Galperin MY

doi

10.1016/j.molcel.2020.01.018

subject

Has Abstract

pub_date

2020-02-06 00:00:00

pages

443-445

issue

3

eissn

1097-2765

issn

1097-4164

pii

S1097-2765(20)30039-3

journal_volume

77

pub_type

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