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Achieving fidelity in homologous recombination despite extreme complexity: informed decisions by molecular profiling.

Abstract：

:In this issue of Molecular Cell, Savir and Tlusty (2010) apply signal detection theory to show that homologous recombination machinery is optimally tuned to find homologous DNA sequences within an exceptionally high background of heterologous sequences.

journal_name

Mol Cell

journal_title

Molecular cell

authors

Rambo RP,Williams GJ,Tainer JA

doi

10.1016/j.molcel.2010.10.032

subject

Has Abstract

pub_date

2010-11-12 00:00:00

pages

347-8

issue

3

eissn

1097-2765

issn

1097-4164

pii

S1097-2765(10)00837-3

journal_volume

40

pub_type

评论,杂志文章

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