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The missing linker: an unexpected role for a histone deacetylase.

Abstract：

:Molecular motors are the long-haul carriers of eukaryotic cells, moving cargos bidirectionally along microtubule tracks. In the December 12th issue of Cell, report that HDAC6, a tubulin deacetylase, functions as an adaptor that links cargos of aggregated protein to the minus end-directed motor, cytoplasmic dynein.

journal_name

Mol Cell

journal_title

Molecular cell

authors

Kopito RR

doi

10.1016/s1097-2765(03)00498-2

subject

Has Abstract

pub_date

2003-12-01 00:00:00

pages

1349-51

issue

6

eissn

1097-2765

issn

1097-4164

pii

S1097-2765(03)00498-2

journal_volume

12

pub_type

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