Abstract:
:This study was undertaken to assess the effects of different tubal occlusion procedures on ovarian function. Three groups of subjects randomized to tubal occlusion by laparoscopy and Yoon ring (24 subjects), minilaparotomy and Yoon ring (19 subjects) and minilaparotomy and Pomeroy (22 subjects), and one separate control group of 26 healthy subjects not using any form of contraception were studied in a prospective design. The characteristics of the menstrual patterns were studied for one year after sterilization. Determination of the circulating progesterone levels were made on days 15, 20 and 25 of menstrual cycles initiated 1, 3, 6 and 12 months following the tubal ligation. In the analysis of the bleeding pattern there was a statistically significant difference in the mean segment length and in the longest bleeding-free interval in the subjects who had been sterilized by minilaparotomy with Yoon ring, when compared to the other two study groups and to the control group. However, the magnitude of this difference in number of days was not considered clinically significant. There was no statistically significant difference in the percentage of ovulatory cycles within the study and the control groups, or when the results of the study groups were compared with each other or to the control group. :This study was undertake to assess the effects of different tubal occlusion procedures on ovarian function. 3 groups of subjects randomized to tubal occlusion by laparoscopy and Yoon ring (24 subjects), minilaparotomy and Yoon ring (19 subjects) and minilaparotomy and Pomeroy (22 subjects), and 1 separate control group of 26 healthy subjects not using any form of contraception were studied in a prospective design. The characteristics of the menstrual patterns were studied for 1 year after sterilization. Determination of the circulating progesterone levels were made on days 15, 20, and 25 of menstrual cycles initiated 1,3,6 and 12 months following the tubal ligation. In the analysis of the bleeding pattern there was a statistically significant difference in the mean segment length and in the longest bleeding-free interval in the subjects who had been sterilized by minilaparotomy with Yoon ring, when compared to the other 2 study groups and to the control group. However, the magnitude of this difference in number of days was not considered clinically significant. There was no statistically significant difference in the % of ovulatory cycles within the study and the control groups, or when the results of the study groups were compared with each other or to the control group. (Author's).
journal_name
Contraceptionjournal_title
Contraceptionauthors
Rivera R,Gaitan JR,Ruiz R,Hurley DP,Arenas M,Flores C,Hernandez ABdoi
10.1016/0010-7824(89)90003-6subject
Has Abstractpub_date
1989-08-01 00:00:00pages
157-69issue
2eissn
0010-7824issn
1879-0518pii
0010-7824(89)90003-6journal_volume
40pub_type
临床试验,杂志文章,随机对照试验相关文献
CONTRACEPTION文献大全abstract:BACKGROUND:Induced fetal demise by intraamniotic injection of digoxin is an alternative to methods using intracardiac or umbilical vein injection. This study was designed to evaluate the effectiveness of intraamniotic injection and the timing of fetal demise after injection. STUDY DESIGN:Twenty-two women had ultrasoni...
journal_title:Contraception
pub_type: 临床试验,杂志文章
doi:10.1016/j.contraception.2009.12.001
更新日期:2010-04-01 00:00:00
abstract::Blood pyrodoxine hydrochloride (vitamin-B6) concentration was determined in 50 women using combined oral contraceptives (OCs), 24 women who received an intramuscular injection of 150 mg medroxyprogesterone acetate (MPA) every 12 weeks, and in 14 women who used an intrauterine device (IUD) at the out-patient contracep...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(74)90078-x
更新日期:1974-04-01 00:00:00
abstract::A drug delivery system which provides a sustained release of norethindrone (NET) and mestranol (ME) for one month after a single intramuscular injection was assessed as a long-acting injectable contraceptive. The system is based upon well defined particle size crystals of the synthetic steroids maintained in suspensio...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(87)90051-5
更新日期:1987-01-01 00:00:00
abstract::Saponins isolated from Sapindus mukorossi have potent spermicidal activity. Morphological changes in human ejaculated spermatozoa after exposure to these saponins were evaluated under Scanning Electron Microscope. The minimum effective concentration (0.05% in spot test) did not affect the surface topography after expo...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(89)90111-x
更新日期:1989-05-01 00:00:00
abstract::Fructose levels and fructolysis index in human semen were analysed to assess a correlation, if any, between the levels of this glycolysable sugar and sperm concentration. Semen was collected from normospermic men and men with azoospermia or oligospermia. Seminal fructose levels were elevated in men with obstructive az...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(89)90062-0
更新日期:1989-03-01 00:00:00
abstract:BACKGROUND:Use of highly effective contraception among women living with HIV is critical to prevent unintended pregnancy and subsequent risk of maternal complications and perinatal HIV transmission. However, it is not known whether use of intrauterine devices (IUDs) among women with advanced HIV disease poses an increa...
journal_title:Contraception
pub_type: 杂志文章,评审
doi:10.1016/j.contraception.2016.06.011
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to assess the presence of ovarian cysts in women using a new low-dose levonorgestrel-releasing intrauterine contraceptive system (LNG-IUS 13.5mg [total content]). STUDY DESIGN:A Phase 3 study assessed LNG-IUS 13.5mg use in healthy women with regular menstrual cycles who requested co...
journal_title:Contraception
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.contraception.2015.01.021
更新日期:2015-05-01 00:00:00
abstract::Injection of a polymer, styrene maleic anhydride (SMA), into the lumen of the vas deferens of rats, was observed to have effective and reversible contraception. The safety evaluation of the polymer, for 90 days, was carried out in Charles Foster male rats. There have been no significant changes in any of the toxicity ...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/s0010-7824(89)80010-1
更新日期:1989-02-01 00:00:00
abstract::The metabolic and hemostatic effects of two oral contraceptives containing 150 mcg desogestrel and 20 mcg ethinyl-estradiol (EE) (MERCILON) or 30 mcg EE (MARVELON) were compared in order to examine the effect of reducing the EE dose in contraceptive pills. Forty-nine women participated in this randomized study during ...
journal_title:Contraception
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0010-7824(93)90141-s
更新日期:1993-09-01 00:00:00
abstract:BACKGROUND:The study was conducted to compare lost to follow-up (LTFU) rates in women having a medical abortion who chose follow-up by in-office ultrasound assessment or serum beta human chorionic gonadotropin (β-hCG) testing. METHODS:This retrospective chart review included 865 women who underwent medical abortion in...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2011.09.007
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE:Assisting women with choosing contraceptive methods that meet their needs and preferences is essential to providing patient-centered care, but research to inform interventions supporting method choice is lacking. An assessment of patient decisional needs for contraceptive method choice may provide insight int...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2017.10.004
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVE:To describe real-world care seeking and contraception provision in one direct to consumer telemedicine platform. STUDY DESIGN:We described encounters with reproductive age female patients between July 2016 and July 2018 seeking contraception on the American Well telemedicine platform. RESULTS:Of 126,712 tot...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2020.01.017
更新日期:2020-05-01 00:00:00
abstract::This prospective cohort study of 257 rural Zimbabwean women was designed to compare patient satisfaction with levonorgestrel subdermal implants (Norplant and reg;) versus tubal ligation (TL) as a method of long-term contraception. Women were equally satisfied with both methods. At 1 year, 96% of Norplant users and 97%...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2004.05.004
更新日期:2004-12-01 00:00:00
abstract::Because RU 486 synergizes with anordrin and its dihydroxylated metabolite to terminate established pregnancy in the rat and rabbit, the interactions of these agents were studied at two days postcoitally in the rat. RU 486 at a dose of 4 mg/kg did not prevent pregnancy when the animals were killed 12 days post insemina...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(93)90038-9
更新日期:1993-04-01 00:00:00
abstract:BACKGROUND:Cyclofem is a combined injectable contraceptive, containing medroxyprogesterone acetate (MPA) and estradiol cypionate. The objective was to characterize the steady-state pharmacokinetics (PK) using tandem liquid chromatography/mass spectrometry and compare these data to a previous PK study of this formulatio...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2012.11.010
更新日期:2013-06-01 00:00:00
abstract::The Indian Council of Medical Research initiated a multicentric trial with prostaglandins in 1976 to assess the safety and efficacy of their use in midtrimester abortions. PGF2 alpha and 15-Me-PGF2 alpha were compared using the intra-amniotic (I.A.) route. 15-Me-PGF2 alpha was also evaluated by extra-amniotic (E.A.) r...
journal_title:Contraception
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0010-7824(78)90048-3
更新日期:1978-12-01 00:00:00
abstract:OBJECTIVE:This study estimates how making oral contraceptive pills (OCPs) available without a prescription may affect contraceptive use, unintended pregnancies and associated contraceptive and pregnancy costs among low-income women. STUDY DESIGN:Based on published figures, we estimate two scenarios [low over-the-count...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2015.01.010
更新日期:2015-05-01 00:00:00
abstract::An injectable method of obtaining vas deferens occlusion is presented. The agent used is styrene maleic anhydride (SMA) with dimethyl sulphoxide as the solvent. The special feature of the approach is that after a period of time, spermatozoa passage is spontaneously reestablished. By varying the dose of SMA administere...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(90)90073-5
更新日期:1990-03-01 00:00:00
abstract::The aim of this guidance is to review the management of unacceptable vaginal bleeding patterns in etonogestrel (ENG)-releasing contraceptive implant users concentrating, where possible, on the evidence for pharmacological treatments and identifying a pragmatic approach where this is not possible. This article was deve...
journal_title:Contraception
pub_type: 杂志文章,评审
doi:10.1016/j.contraception.2010.08.001
更新日期:2011-03-01 00:00:00
abstract::9-Deoxo-16, 16-dimethyl-9-methylene-PGE2 is a new prostaglandin analogue which is stable in suppository form. Estimates of potential for gastrointestinal side effects in monkey in vivo indicated that the frequency of diarrhea was low with retention of uterine stimulating potency. In the present study the effect of the...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(80)90059-1
更新日期:1980-08-01 00:00:00
abstract::RU 486 and three of its metabolites (RU 42633-monodemethyl, RU 42848-didemethyl, and RU 42698-hydroxymetabolite) were determined by HPLC in plasma from nine non-pregnant and 36 pregnant women. Each non-pregnant subject took an oral dose of RU 486 (25, 100, 400 and 600 mg consecutively) once per menstrual cycle. Six of...
journal_title:Contraception
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0010-7824(93)90004-q
更新日期:1993-08-01 00:00:00
abstract::Primary cultures of rat Leydig and Sertoli cells were used to evaluate the direct effects of GTW on testicular cells and to compare these to the effects of gossypol acetate. Both GTW and gossypol acetate can affect the survival of Leydig and Sertoli cells. But Sertoli cells are much more sensitive than Leydig cells, e...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/0010-7824(92)90069-6
更新日期:1992-03-01 00:00:00
abstract:OBJECTIVE:The purpose of this study is to measure the accessibility to purchase oral and transdermal contraceptives over the Internet for low- and high-risk individuals. METHODS:The Internet was used to search for and order both oral and transdermal contraceptives. Using the "Google" search engine to locate online pha...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2005.10.001
更新日期:2006-04-01 00:00:00
abstract::Data from published studies of the quantity of medroxyprogesterone acetate and/or its metabolites in the milk of lactating women receiving Depo-Provera for contraception is extrapolated into the amount of drug ingested daily by a theoretically average infant. Comparisons are made with the results of similar studies in...
journal_title:Contraception
pub_type: 杂志文章,评审
doi:10.1016/0010-7824(81)90027-5
更新日期:1981-04-01 00:00:00
abstract::In this open-label, randomized study we compared the influence of a new oral contraceptive containing 30 microg ethinylestradiol and 3 mg drospirenone (EE + DRSP = Yasmin), with a reference preparation containing 30 microg ethinylestradiol and 150 microg desogestrel (EE + DSG = Marvelon) on the lipid profile. The prim...
journal_title:Contraception
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.contraception.2003.11.003
更新日期:2004-04-01 00:00:00
abstract:BACKGROUND:Developing an objective, reliable method to determine semen exposure in cervicovaginal fluids is important for accurately studying the efficacy of vaginal microbicides and contraceptives. Y-chromosome biomarkers offer better stability, sensitivity, and specificity than protein biomarkers. TSPY4 belongs to th...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2012.11.022
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:Hypertension is recognized as a major risk factor for coronary, cerebral and renal vascular disease. Hormonal methods of contraception may increase the risk for cardiovascular events. We evaluated whether the combined hormonal contraceptive vaginal ring that releases 15-mcg ethinylestradiol and 120 mcg of et...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2013.04.003
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:The FDA approval of mifepristone in 2000 broadened the available options for abortion. The aim of this study was to evaluate whether physicians in New Mexico have integrated the use of mifepristone into their practice. STUDY DESIGN:We performed a mail-out survey of New Mexico Obstetrician Gynecologists (Ob-...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2010.11.021
更新日期:2011-08-01 00:00:00
abstract:PURPOSE:This prospective study aimed to assess the possible effects of the levonorgestrel-releasing intrauterine system (LNG-IUS) on serum lipids and fasting blood glucose levels over a period of 1 year. METHODS:Forty-eight premenopausal women, attending our gynecology clinic with the complaint of menorrhagia, were en...
journal_title:Contraception
pub_type: 杂志文章
doi:10.1016/j.contraception.2005.12.005
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:Women with depressive or bipolar disorders are at an increased risk for unintended pregnancy. OBJECTIVE:To examine the safety of hormonal contraception among women with depressive and bipolar disorders. METHODS:We searched for articles published through January 2016 on the safety of using any hormonal cont...
journal_title:Contraception
pub_type: 杂志文章,评审
doi:10.1016/j.contraception.2016.06.012
更新日期:2016-12-01 00:00:00