Abstract：
BACKGROUND:Lesions of the angular gyrus (AnG) region of human parietal cortex do not cause amnesia, but appear to be associated with reduction in the ability to consciously experience the reliving of previous events. OBJECTIVES/HYPOTHESIS:We used continuous theta burst stimulation to test the hypothesis that the cognitive mechanism implicated in this memory deficit might be the integration of retrieved sensory event features into a coherent multimodal memory representation. METHODS:Healthy volunteers received stimulation to AnG or a vertex control site after studying stimuli that each comprised a visual object embedded in a scene, with the name of the object presented auditorily. Participants were then asked to make memory judgments about the studied stimuli that involved recollection of single event features (visual or auditory), or required integration of event features within the same modality, or across modalities. RESULTS:Participants' ability to retrieve context features from across multiple modalities was significantly reduced after AnG stimulation compared to stimulation of the vertex. This effect was observed only for the integration of cross-modal context features but not for integration of features within the same modality, and could not be accounted for by task difficulty as performance was matched across integration conditions following vertex stimulation. CONCLUSION:These results support the hypothesis that AnG is necessary for the multimodal integration of distributed cortical episodic features into a unified conscious representation that enables the experience of remembering.
journal_name
Brain Stimuljournal_title
Brain stimulationauthors
Yazar Y,Bergström ZM,Simons JSdoi
10.1016/j.brs.2017.02.011subject
Has Abstractpub_date
2017-01-01 00:00:00pages
624-629issue
3eissn
1935-861Xissn
1876-4754pii
S1935-861X(17)30618-6journal_volume
10pub_type
杂志文章abstract：BACKGROUND:Transcranial magnetic stimulation (TMS) is a non-invasive neuromodulatory technique that has broad diagnostic and therapeutic potential across a range of neurological and psychiatric diseases. OBJECTIVE:This study utilises a bibliometric approach to systematically and comprehensively evaluate the literature...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2019.01.002
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:Dopaminergic activity within the dorsolateral prefrontal cortex (dlPFC) has been implicated in the control of cognitive flexibility. Much of the evidence for a causative relationship between cognitive flexibility and dopamine has come from animal studies, whilst human data have largely been correlational. O...
journal_title：Brain stimulation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.brs.2018.12.001
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:Temporal resolution of cortical, auditory processing mechanisms is suggested to be linked to peak frequency of neuronal gamma oscillations in auditory cortex areas (individual gamma frequency, IGF): Individuals with higher IGF tend to have better temporal resolution. HYPOTHESIS:Modulating ongoing gamma acti...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2017.10.008
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:Low-level light therapy (LLLT) with transcranial laser is a non-invasive form of neuroenhancement shown to regulate neuronal metabolism and cognition. Attention bias modification (ABM) is a cognitive intervention designed to improve depression by decreasing negative attentional bias, but to date its efficacy...
journal_title：Brain stimulation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.brs.2016.05.009
更新日期：2016-09-01 00:00:00
abstract：BACKGROUND:Dorsomedial prefrontal cortex (DMPFC) repetitive transcranial magnetic stimulation (rTMS) is a novel intervention for treatment-refractory depression (TRD). To date, many open-label case series and one randomized controlled trial of modest sample size have provided preliminary evidence that DMPFC-rTMS is an ...
journal_title：Brain stimulation
pub_type： 信件,随机对照试验
doi：10.1016/j.brs.2019.10.020
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:Noninvasive brain stimulation is a powerful way to modify excitability of the cerebral cortex in humans and is increasingly used to treat psychiatric disorders. The observed clinical effects are in the moderate range and it has been suggested that the efficiency of brain stimulation depends on the underlying...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2010.07.002
更新日期：2011-04-01 00:00:00
abstract：:The intensity of sound emanating from the discharge of magnetic coils used in repetitive transcranial magnetic stimulation (rTMS) can potentially cause acoustic trauma. Per Occupational Safety and Health Administration (OSHA) standards for safety of noise exposure, hearing protection is recommended beyond restricted l...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2014.01.056
更新日期：2014-05-01 00:00:00
abstract：:The human motor cortex can be activated by transcranial magnetic stimulation (TMS) evoking a high-frequency repetitive discharge of corticospinal neurones. The exact physiologic mechanisms producing the corticospinal activity still remain unclear because of the complexity of the interactions between the currents induc...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2011.07.008
更新日期：2012-10-01 00:00:00
abstract：BACKGROUND:Burning mouth syndrome (BMS) is a burning oral sensation without any corresponding abnormal findings. In some cases, BMS is refractory to pharmacologic treatments. Repetitive transcranial magnetic stimulation (rTMS) over left prefrontal cortex induces analgesic effect in both acute and chronic pain. However,...
journal_title：Brain stimulation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.brs.2015.10.005
更新日期：2016-03-01 00:00:00
abstract：BACKGROUND:Repetitive transcranial magnetic stimulation (rTMS) for the experimental treatment of tinnitus or auditory hallucinations aims at a modulation of cortical activity in areas of auditory perception and processing. Continuous theta burst stimulation (cTBS) is a patterned rTMS paradigm with lower stimulation int...
journal_title：Brain stimulation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.brs.2012.10.005
更新日期：2013-07-01 00:00:00
abstract：BACKGROUND:Vagus nerve stimulation (VNS) significantly reduces infarct volume in rat models of cerebral ischemia, but the mechanism of this protective effect remains open. HYPOTHESIS:This study tested the hypothesis that non-invasive VNS (nVNS), during transient middle cerebral artery occlusion (MCAO), protects the bl...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2018.01.034
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:Transcranial direct current stimulation (tDCS) was recently shown to promote recovery of voluntary signs of consciousness in some patients in minimally conscious state (MCS). However, it remains unclear why clinical improvement is only observed in a subgroup of patients. OBJECTIVES:In this retrospective stu...
journal_title：Brain stimulation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.brs.2015.07.024
更新日期：2015-11-01 00:00:00
abstract：BACKGROUND:Deep brain stimulation (DBS) has emerged as a potential therapeutic strategy in the treatment of neurological disorders including epilepsy. However, the cellular mechanism responsible for the effects of DBS remains largely undefined. Therefore, using electrophysiological approach, we aimed to determine the a...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2012.11.001
更新日期：2013-07-01 00:00:00
abstract：BACKGROUND:Volume increases of the hippocampus after electroconvulsive therapy (ECT) are a robust finding, pointing into the direction of neurogenesis. However, such volumetric increases could also be explained by edema and/or neuroplastic changes (such as angiogenesis). OBJECTIVES:If edema explains the volume increas...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2020.04.017
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:Recently, navigated transcranial magnetic stimulation (nTMS) has been suggested to be useful in preoperative functional localization of motor cortex in patients having tumors close to the somatomotor cortex. Resection of tumors in anatomically predicted eloquent areas without adverse effects have emphasized ...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2012.04.012
更新日期：2013-05-01 00:00:00
abstract：OBJECTIVE:To examine the effects of transcranial direct current stimulation (tDCS) on objective and subjective indexes of exercise performance. DESIGN:Systematic review and meta-analysis. DATA SOURCES:A systematic literature search of electronic databases (PubMed, Web of Science, Scopus, Google Scholar) and reference...
journal_title：Brain stimulation
pub_type： 杂志文章,meta分析
doi：10.1016/j.brs.2018.12.002
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:Deep brain stimulation (DBS) has been used for neuropsychiatric disorders in clinical and research settings for almost 50 years now. Recent evidence demonstrates some efficacy in treating obsessive-compulsive disorder and major depression in patients refractory to other treatment modalities beyond single cas...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2010.03.002
更新日期：2011-01-01 00:00:00
abstract：:Inhibitory control mechanisms are important in a range of behaviours to prevent execution of motor acts which, having been planned, are no longer necessary or appropriate. Examples of this can be seen in a range of sports, such as cricket and baseball, where the choice between execution and inhibition of a bat swing m...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2012.03.012
更新日期：2012-04-01 00:00:00
abstract：INTRODUCTION:Previous work in the language domain has shown that 10 Hz rTMS of the left or right posterior inferior frontal gyrus (pIFG) in the prefrontal cortex impaired phonological decision-making, arguing for a causal contribution of the bilateral pIFG to phonological processing. However, the neurophysiological cor...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2019.06.021
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVES:Vagus nerve stimulation represents an established treatment strategy for epilepsy and affective disorders. Recently, positive effects were also shown in animals and humans with tinnitus. Here we report the results of an open pilot study exploring feasibility, safety and efficacy of tVNS in the treatment of c...
journal_title：Brain stimulation
pub_type： 临床试验,杂志文章
doi：10.1016/j.brs.2014.05.003
更新日期：2014-09-01 00:00:00
abstract：BACKGROUND:Direct stimulation of the vagus nerve in the neck via surgically implanted electrodes is protective in animal models of stroke. We sought to determine the safety and efficacy of a non-invasive cervical VNS (nVNS) method using surface electrodes applied to the skin overlying the vagus nerve in the neck in a m...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2015.11.008
更新日期：2016-03-01 00:00:00
abstract：BACKGROUND:Repetitive transcranial magnetic stimulation (rTMS) is an effective treatment for depression, but only some individuals respond. Predicting response could reduce patient and clinical burden. Neural activity related to working memory (WM) has been related to mood improvements, so may represent a biomarker for...
journal_title：Brain stimulation
pub_type： 临床试验,杂志文章
doi：10.1016/j.brs.2017.10.015
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:Neural oscillations reflect rapidly changing brain excitability states. We have demonstrated previously with EEG-triggered transcranial magnetic stimulation (TMS) of human motor cortex that the positive vs. negative peak of the sensorimotor μ-oscillation reflect corticospinal low-vs. high-excitability states...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2020.09.005
更新日期：2020-01-01 00:00:00
abstract：:Deep brain stimulation (DBS) has evolved into a powerful clinical therapy for a range of neurological disorders, but even with impressive clinical growth, DBS technology has been relatively stagnant over its history. However, enhanced collaborations between neural engineers, neuroscientists, physicists, neurologists, ...
journal_title：Brain stimulation
pub_type： 杂志文章,评审
doi：10.1016/j.brs.2014.07.039
更新日期：2015-01-01 00:00:00
abstract：BACKGROUND:Repetitive transcranial magnetic stimulation (rTMS) has been proposed for stabilizing the antidepressant effect of sleep deprivation (SD) by preventing the relapse after a night of recovery sleep. In this study, we aimed to replicate these data coming from a small pilot study in a larger patient sample. MET...
journal_title：Brain stimulation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.brs.2011.02.005
更新日期：2012-04-01 00:00:00
abstract：BACKGROUND:Theta burst stimulation (TBS) is a pattern of repetitive transcranial magnetic stimulation that has been demonstrated to facilitate or suppress human corticospinal excitability when applied intermittently (iTBS) or continuously (cTBS), respectively. While the fundamental pattern of TBS, consisting of bursts ...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2013.12.007
更新日期：2014-03-01 00:00:00
abstract：BACKGROUND:Vagus nerve stimulation (VNS) is indicated for treatment-resistant epilepsy and depression. Electrophysiologic recordings in the rat brain have shown that VNS promptly increases the firing rate of NE neurons and subsequently that of 5-HT neurons. Thus far, it appears that the standard stimulation parameters ...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2011.04.005
更新日期：2012-07-01 00:00:00
abstract：BACKGROUND:Although some studies have reported significant reductions in food cravings following the single-session of repetitive transcranial magnetic stimulation (rTMS), there is little research on the effects of multi-session of rTMS on food consumption and body weight in obese subjects. OBJECTIVE:We conducted 4-we...
journal_title：Brain stimulation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.brs.2019.07.020
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:Task switching, defined as the ability to flexibly switch between tasks in the face of goal shifting, is a central mechanism in cognitive control. Task switching is thought to involve both prefrontal cortex (PFC) and parietal regions. Our previous work has shown that it is possible to modulate set shifting t...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2012.10.006
更新日期：2013-07-01 00:00:00
abstract：BACKGROUND:Vagus nerve stimulation (VNS) paired with forelimb training drives robust, specific reorganization of movement representations in the motor cortex. The mechanisms that underlie VNS-dependent enhancement of map plasticity are largely unknown. The cholinergic nucleus basalis (NB) is a critical substrate in cor...
journal_title：Brain stimulation
pub_type： 杂志文章
doi：10.1016/j.brs.2015.12.007
更新日期：2016-03-01 00:00:00
