A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation.

abstract：:Epstein-Barr virus (EBV) is associated with about 6 to 16% of gastric carcinoma cases worldwide. Expression of the EBV microRNAs (miRNAs) was observed in B cells and nasopharyngeal carcinoma cells infected with EBV. However, it is not clear if the EBV miRNAs are expressed in EBV-associated gastric carcinomas (EBVaGCs)...

journal_title：Journal of virology

authors： Kim DN,Chae HS,Oh ST,Kang JH,Park CH,Park WS,Takada K,Lee JM,Lee WK,Lee SK

更新日期：2007-01-01 00:00:00

abstract：:Deoxyribonucleoside triphosphates are incorporated into T4 DNA in infected cells treated with toluene. Under the proper conditions the incorporation is controlled by the known T4 DNA polymerase and proceeds by a semiconservative mechanism. Both strands of the phage DNA are replicated into a high molecular weight proge...

journal_title：Journal of virology

authors： Miller RC Jr,Taylor DM,MacKay K,Smith HW

更新日期：1973-12-01 00:00:00

abstract：:The genome of the defective interfering (DI) mouse hepatitis virus DI-a carries a large open reading frame (ORF) consisting of ORF1a, ORF1b, and nucleocapsid sequences. To test whether this fusion ORF is important for DI virus replication, we constructed derivatives of the DI-a genome in which the reading frame was tr...

journal_title：Journal of virology

authors： de Groot RJ,van der Most RG,Spaan WJ

更新日期：1992-10-01 00:00:00

abstract：:The major phosphoprotein common to woolly monkey sarcoma virus, gibbon ape lymphosarcoma virus, and type C viruses of the lower mammalian species (mouse, rat, cat), with the exception of the endogenous cat virus (RD-114), is the polypeptide of about 12,000 molecular weight. The protein-phosphate bond in this polypepti...

journal_title：Journal of virology

authors： Pal BK,McAllister RM,Gardner MB,Roy-Burman P

更新日期：1975-07-01 00:00:00

abstract：:Pseudomonas aeruginosa myovirus KZ has a 270-kb genome within a T=27 icosahedral capsid that contains a large, unusual, and structurally well-defined protein cylindrical inner body (IB) spanning its interior. Proteolysis forms a pivotal stage in KZ head and IB morphogenesis, with the protease gp175 cleaving at least 1...

journal_title：Journal of virology

authors： Thomas JA,Black LW

更新日期：2013-08-01 00:00:00

abstract：:Recent studies have established the presence of human T-cell lymphoma/leukemia virus type I (HTLV-I) in Melanesia. An HTLV-I strain, PNG-1, has now been isolated from a healthy member of the Hagahai, a remote, recently contacted group in Papua New Guinea. To further characterize PNG-1, we employed polymerase chain rea...

journal_title：Journal of virology

authors： Sherman MP,Saksena NK,Dube DK,Yanagihara R,Poiesz BJ

更新日期：1992-04-01 00:00:00

abstract：:We have analyzed the production of tumor necrosis factor alpha (TNF-alpha) induced by in vitro infection with African swine fever (ASF) virus (ASFV) and the systemic and local release of this inflammatory cytokine upon in vivo infection. An early increase in TNF-alpha mRNA expression was detected in ASFV-infected alve...

journal_title：Journal of virology

authors： Gómez del Moral M,Ortuño E,Fernández-Zapatero P,Alonso F,Alonso C,Ezquerra A,Domínguez J

更新日期：1999-03-01 00:00:00

abstract：:Deletion mutants of simian virus 40 (SV40) with lesions at the three DdeI sites near the 3' end of the early region were constructed. Mutants with deletions at 0.203 and 0.219 map units (mu) which did not change the large T antigen reading frame were viable. This extends slightly the upstream boundary for the location...

journal_title：Journal of virology

authors： Tornow J,Cole CN

更新日期：1983-09-01 00:00:00

abstract：:Smallpox was eradicated more than 10 years ago, but infection with another Orthopoxvirus, monkeypox virus, can result in a clinical picture resembling smallpox. Human infection with monkeypox virus is extremely rare, not easily transmitted, and confined to the rain forest belt of Africa (Z. Jezek and F. Fenner, p. 81-...

journal_title：Journal of virology

authors： Douglass N,Dumbell K

更新日期：1992-12-01 00:00:00

abstract：:Immunological comparisons were made of baculovirus structural proteins by using a modification of the radioimmunological techniques described by Renart et al. (Proc. Natl. Acad. Sci. U.S.A. 76: 3116-3120, 1979) and Towbin et al. (Proc. Natl. Acad. Sci. U.S.A. 76: 4350-4354, 1979). Viral proteins were electrophoresed i...

journal_title：Journal of virology

authors： Smith GE,Summers MD

更新日期：1981-07-01 00:00:00

abstract：:Molluscs, comprising one of the most successful phyla, lack clear evidence of adaptive immunity and yet thrive in the oceans, which are rich in viruses. There are thought to be nearly 120,000 species of Mollusca, most living in marine habitats. Despite the extraordinary abundance of viruses in oceans, molluscs often h...

journal_title：Journal of virology

authors： Dang VT,Benkendorff K,Green T,Speck P

更新日期：2015-08-01 00:00:00

abstract：:Zika virus (ZIKV), a mosquito-transmitted flavivirus, is linked to microcephaly and other neurological defects in neonates and Guillain-Barré syndrome in adults. The molecular mechanisms regulating ZIKV infection and pathogenic outcomes are incompletely understood. Signaling by the mechanistic (mammalian) target of ra...

journal_title：Journal of virology

authors： Sahoo BR,Pattnaik A,Annamalai AS,Franco R,Pattnaik AK

更新日期：2020-10-27 00:00:00

abstract：:The morphology and development of four members of the reticuloendotheliosis virus group were studied by transmission electron microscopy. Virions of duck spleen necrosis virus, duck infectious anemia virus, chicken syncytial virus, and reticuloendotheliosis virus strain T are sperical with a diameter of approximately ...

journal_title：Journal of virology

authors： Kang CY,Wong TC,Holmes KV

更新日期：1975-10-01 00:00:00

abstract：:The foot-and-mouth disease virus (FMDV) capsid protein precursor, P1-2A, is cleaved by 3C(pro) to generate VP0, VP3, VP1, and the peptide 2A. The capsid proteins self-assemble into empty capsid particles or viruses which do not contain 2A. In a cell culture-adapted strain of FMDV (O1 Manisa [Lindholm]), three differen...

journal_title：Journal of virology

authors： Gullberg M,Polacek C,Bøtner A,Belsham GJ

更新日期：2013-11-01 00:00:00

abstract：:The mitogen-activated protein (MAP) kinase signal transduction pathway is an intracellular signaling cascade which mediates cellular responses to growth and differentiation factors. The MAP kinase pathway can be activated by a wide range of stimuli dependent on the cell types, and this is normally a transient response...

journal_title：Journal of virology

authors： Gu Z,Matlashewski G

更新日期：1995-12-01 00:00:00

abstract：:TR1.3 is a Friend murine leukemia virus (MLV) that induces selective syncytium induction (SI) of brain capillary endothelial cells (BCEC), intracerebral hemorrhage, and death. Syncytium induction by TR1.3 has been mapped to a single tryptophan-to-glycine conversion at position 102 of the envelope glycoprotein (Env102)...

journal_title：Journal of virology

authors： Murphy SL,Chung-Landers M,Honczarenko M,Gaulton GN

更新日期：2006-05-01 00:00:00

abstract：:Recently, it was demonstrated that the coxsackievirus B3 variant PD (CVB3 PD) is able to infect coxsackievirus-adenovirus receptor (CAR)-lacking cells by using heparan sulfates (HS) as additional receptors (A. E. Zautner, U. Korner, A. Henke, C. Badorff, and M. Schmidtke, J. Virol. 77:10071-10077, 2003). For this stud...

journal_title：Journal of virology

authors： Zautner AE,Jahn B,Hammerschmidt E,Wutzler P,Schmidtke M

更新日期：2006-07-01 00:00:00

abstract：:The agent(s) responsible for sporadic non-A, non-B hepatitis in humans was serially transmitted in rhesus monkeys by intravenous inoculation of the stool extract from a patient. A novel agent called HFV (hepatitis French [origin] virus) was present as 27- to 37-nm particles in the infectious stool extract. Hepatopathi...

journal_title：Journal of virology

authors： Deka N,Sharma MD,Mukerjee R

更新日期：1994-12-01 00:00:00

abstract：UNLABELLED:Coronaviruses (CoVs) are unique in encoding a 3'→5' exoribonuclease within nonstructural protein 14 (nsp14-ExoN) that is required for high-fidelity replication, likely via proofreading. nsp14 associates with the CoV RNA-dependent RNA polymerase (nsp12-RdRp), and nsp14-ExoN activity is enhanced by binding nsp...

journal_title：Journal of virology

authors： Smith EC,Case JB,Blanc H,Isakov O,Shomron N,Vignuzzi M,Denison MR

更新日期：2015-06-01 00:00:00

abstract：:The entry of animal viruses into cells is associated with permeabilization of the infected cells to protein toxins such as alpha-sarcin (C. Fernández-Puentes and L. Carrasco, Cell 20:769-775, 1980). This phenomenon has been referred to as "the early permeabilization by animal viruses" (L. Carrasco, Virology 113:623-62...

journal_title：Journal of virology

authors： Almela MJ,González ME,Carrasco L

更新日期：1991-05-01 00:00:00

abstract：:Extracts from poliovirus-infected HeLa cells are unable to translate vesicular stomatitis virus or cellular mRNAs in vitro, probably reflecting the poliovirus-induced inhibition of host cell protein synthesis which occurs in vivo. Crude initiation factors from uninfected HeLa cells are able to restore translation of v...

journal_title：Journal of virology

authors： Hansen J,Etchison D,Hershey JW,Ehrenfeld E

更新日期：1982-04-01 00:00:00

abstract：:Epstein-Barr virus (EBV) infection leads to lifelong viral persistence through its latency in B cells. EBV-specific T cells control reactivations and prevent the development of EBV-associated malignancies in most healthy carriers, but infection can sometimes cause chronic disease and malignant transformation. Epstein-...

journal_title：Journal of virology

authors： Leskowitz RM,Zhou XY,Villinger F,Fogg MH,Kaur A,Lieberman PM,Wang F,Ertl HC

更新日期：2013-08-01 00:00:00

abstract：:Antibody to the capsid (PORF2) protein of hepatitis E virus (HEV) is sufficient to confer immunity, but knowledge of B-cell epitopes in the intact capsid is limited. A panel of murine monoclonal antibodies (MAbs) was generated following immunization with recombinant ORF2.1 protein, representing the C-terminal 267 amin...

journal_title：Journal of virology

authors： Riddell MA,Li F,Anderson DA

更新日期：2000-09-01 00:00:00

abstract：:Surface glycoproteins of enveloped virus are potent elicitors of type I interferon (IFN)-mediated antiviral responses in a way that may be independent of the well-studied genome-mediated route. However, the viral glycoprotein determinants responsible for initiating the IFN response remain unidentified. In this study, ...

journal_title：Journal of virology

authors： Chico V,Martinez-Lopez A,Ortega-Villaizan M,Falco A,Perez L,Coll JM,Estepa A

更新日期：2010-07-01 00:00:00

abstract：:The relatively small package capacity (less than 5 kb) of adeno-associated virus (AAV) vectors has been effectively doubled with the development of dual-vector heterodimerization approaches. However, the efficiency of such dual-vector systems is limited not only by the extent to which intermolecular recombination occu...

journal_title：Journal of virology

authors： Yan Z,Zak R,Zhang Y,Engelhardt JF

更新日期：2005-01-01 00:00:00

abstract：:We established a system for propagation of Sindbis virus (SIN)-based replicons in tissue culture in the form of a tricomponent genome virus. Three RNA fragments containing complementing genetic information required for virus replication are packaged into separate viral particles, and each cell produces at least 1,000 ...

journal_title：Journal of virology

authors： Fayzulin R,Gorchakov R,Petrakova O,Volkova E,Frolov I

更新日期：2005-01-01 00:00:00

abstract：:We have amplified by the polymerase chain reaction, cloned, and sequenced genomic segments of 118 human papillomavirus type 16 (HPV-16) isolates from 76 cervical biopsy, 14 cervical smear, 3 vulval biopsy, 2 penile biopsy, 2 anal biopsy, and 1 vaginal biopsy sample and two cell lines. The specimens were taken from pat...

journal_title：Journal of virology

authors： Chan SY,Ho L,Ong CK,Chow V,Drescher B,Dürst M,ter Meulen J,Villa L,Luande J,Mgaya HN

更新日期：1992-04-01 00:00:00

abstract：:Two major DNA variants have been isolated from serially propagated stocks of the WR strain of vaccinia virus. Restriction enzyme mapping of the two variants with HindIII, AvaI, XhoI, SstII, and SmaI revealed a 6.3-megadalton deletion in the smaller DNA variant. The deletion was mapped at ca. 6.8 megadaltons in from th...

journal_title：Journal of virology

authors： Panicali D,Davis SW,Mercer SR,Paoletti E

更新日期：1981-03-01 00:00:00

abstract：:HIV CRF01_AE accounted for 84% of the recent infections among men who have sex with men (MSM) in Liaoning Province of northeastern China. CRF01_AE strains were grouped into two distinct clusters (designated clusters 1 and 2) that were also detected in other regions in China. Phylodynamics study revealed that these two...

journal_title：Journal of virology

authors： An M,Han X,Xu J,Chu Z,Jia M,Wu H,Lu L,Takebe Y,Shang H

更新日期：2012-11-01 00:00:00

abstract：:We have constructed two point mutants of Rous sarcoma virus in which the amino-terminal glycine residue of the transforming protein, p60src, was changed to an alanine or a glutamic acid residue. Both mutant proteins failed to become myristylated and, more importantly, no longer transformed cells. The lack of transform...

journal_title：Journal of virology

authors： Buss JE,Kamps MP,Gould K,Sefton BM

更新日期：1986-05-01 00:00:00