Sindbis virus with a tricomponent genome.

abstract：:Equine infectious anemia virus was found to be comprised of fourteen polypeptides of molecular weight ranging from 10,000 to 79,000. Eighty percent of the virion protein was accounted for by five polypeptides, including two non-glycosylated components (p29 and p13) comprising one-half of the virion protein and three g...

journal_title：Journal of virology

authors： Cheevers WP,Ackley CM,Crawford TB

更新日期：1978-12-01 00:00:00

abstract：:We are exploring the use of interferon (IFN) genes for somatic cell gene therapy and have investigated the possibility of transforming cells into low constitutive IFN producers over prolonged periods of time without impeding cell survival or replication. Here we report the possibility of conferring a permanent antivir...

journal_title：Journal of virology

authors： Seif I,De Maeyer E,Riviere I,De Maeyer-Guignard J

更新日期：1991-02-01 00:00:00

abstract：:The herpes simplex virus (HSV) heterodimer gE/gI and another membrane protein, US9, which has neuron-specific effects, promote the anterograde transport of virus particles in neuronal axons. Deletion of both HSV gE and US9 blocks the assembly of enveloped particles in the neuronal cytoplasm, which explains why HSV vir...

journal_title：Journal of virology

authors： DuRaine G,Wisner TW,Johnson DC

更新日期：2020-11-09 00:00:00

abstract：:The J-F intercistronic region of the genomes of bacteriophages phi X174 and G4 is transcribed but not translated. It contains the potential for a perfectly base-paired hairpin structure, which has been proposed to act as a terminator of transcription or as a regulatory region for mRNA turnover (or both). We measured p...

journal_title：Journal of virology

authors： Romantschuk ML,Müller UR

更新日期：1983-10-01 00:00:00

abstract：:Dengue virus (DEN) causes dengue fever and dengue hemorrhagic fever/dengue shock syndrome, which are major public health problems worldwide. The immune factors that control DEN infection or contribute to severe disease are neither well understood nor easy to examine in humans. In this study, we used wild-type and cong...

journal_title：Journal of virology

authors： Shresta S,Kyle JL,Snider HM,Basavapatna M,Beatty PR,Harris E

更新日期：2004-03-01 00:00:00

abstract：:The adenovirus major late transcription unit (MLTU) encodes five families of mRNAs, L1 to L5, each distinguished by a unique poly(A) site. Use of the promoter-proximal L1 poly(A) site predominates during early infection, whereas poly(A) site choice shifts to the promoter-distal sites during late infection. A mini-MLTU...

journal_title：Journal of virology

authors： Gilmartin GM,Hung SL,DeZazzo JD,Fleming ES,Imperiale MJ

更新日期：1996-03-01 00:00:00

abstract：:Retinoic acid-inducible gene I (RIG-I) is a key sensor for recognizing nucleic acids derived from RNA viruses and triggers beta interferon (IFN-β) production. Because of its important role in antiviral innate immunity, the activity of RIG-I must be tightly controlled. Here, we used yeast two-hybrid screening to identi...

journal_title：Journal of virology

authors： Li MT,Di W,Xu H,Yang YK,Chen HW,Zhang FX,Zhai ZH,Chen DY

更新日期：2013-09-01 00:00:00

abstract：:When herpes simplex virus was inoculated into the flank of a BALB/c mouse by scarification, the local replication of virus was followed by the establishment of an acute ganglionic infection. The subsequent centrifugal spread of this virus along nerves to the skin of the whole dermatome led to the development of a band...

journal_title：Journal of virology

authors： Simmons A,Nash AA

更新日期：1985-03-01 00:00:00

abstract：:The pathway of envelopment and egress of the varicella-zoster virus (VZV) and the primary site of viral production within the epidermal layer of the skin are not fully understood. There are several hypotheses to explain how the virus may receive an envelope as it travels to the surface of the monolayer. In this study,...

journal_title：Journal of virology

authors： Harson R,Grose C

更新日期：1995-08-01 00:00:00

abstract：:The foot-and-mouth disease virus (FMDV) capsid is highly acid labile, but introduction of amino acid replacements, including an N17D change in VP1, can increase its acid resistance. Using mutant VP1 N17D as a starting point, we isolated a virus with higher acid resistance carrying an additional replacement, VP2 H145Y,...

journal_title：Journal of virology

authors： Vázquez-Calvo A,Caridi F,Sobrino F,Martín-Acebes MA

更新日期：2014-03-01 00:00:00

abstract：:Insertion of a region, including the 18-nucleotide-long intergenic sequence between genes 6 and 7 of mouse hepatitis virus (MHV) genomic RNA, into an MHV defective interfering (DI) RNA leads to transcription of subgenomic DI RNA in helper virus-infected cells (S. Makino, M. Joo, and J. K. Makino, J. Virol. 66:6031-604...

journal_title：Journal of virology

authors： Makino S,Joo M

更新日期：1993-06-01 00:00:00

abstract：:Griffithsin, which binds N-linked glycans on gp120 to prevent HIV entry, has the most potent HIV-1 inhibitory activity described for any antiviral lectin and is being developed for topical preexposure prophylaxis. The current studies were designed to further assess its potential by exploring its activity against herpe...

journal_title：Journal of virology

authors： Nixon B,Stefanidou M,Mesquita PM,Fakioglu E,Segarra T,Rohan L,Halford W,Palmer KE,Herold BC

更新日期：2013-06-01 00:00:00

abstract：UNLABELLED:Microtubule transport of circovirus from the periphery of the cell to the nucleus is essential for viral replication in early infection. How the microtubule is recruited to the viral cargo remains unclear. In this study, we observed that circovirus trafficking is dependent on microtubule polymerization and t...

journal_title：Journal of virology

authors： Cao J,Lin C,Wang H,Wang L,Zhou N,Jin Y,Liao M,Zhou J

更新日期：2015-03-01 00:00:00

abstract：:Actinophage MSP2 is infectious for Streptomyces venezuelae S13. Based upon electron microscopy of coliphage T4 mixed with MSP2, MSP2 had a head about 48 +/- 2 nm wide and 87 +/- 5 nm long. DNA from polyoma virus and from coliphages T4 and T7 served as reference markers in estimating the molecular weight of MSP2 DNA fr...

journal_title：Journal of virology

authors： Lancaster WD,Jones LA

更新日期：1975-09-01 00:00:00

abstract：:Changes in T-cell function are a hallmark of human immunodeficiency virus type 1 (HIV-1) infection, but the pathogenic mechanisms leading to these changes are unclear. We examined the gene expression profiles in ex vivo human CD4+ and CD8+ T cells from untreated HIV-1-infected individuals at different clinical stages ...

journal_title：Journal of virology

authors： Hyrcza MD,Kovacs C,Loutfy M,Halpenny R,Heisler L,Yang S,Wilkins O,Ostrowski M,Der SD

更新日期：2007-04-01 00:00:00

abstract：:The full-length sequence of a satellite RNA (sat-RNA) of Beet black scorch virus isolate X (BBSV-X) was determined. This agent is 615 nucleotides long and lacks extensive sequence homology with its helper virus or with other reported viruses. Purified virus particles contained abundant single-stranded plus-sense monom...

journal_title：Journal of virology

authors： Guo LH,Cao YH,Li DW,Niu SN,Cai ZN,Han CG,Zhai YF,Yu JL

更新日期：2005-03-01 00:00:00

abstract：:The Borna disease virus (BDV) is the prototype member of the Bornaviridae, and it replicates in the cell nucleus. The BDV p24P and p40N proteins carry nuclear localization signals (NLS) and are found in the nuclei of infected cells. The BDV p10 protein does not have an NLS, but it binds with P and/or N and is transloc...

journal_title：Journal of virology

authors： Malik TH,Kishi M,Lai PK

更新日期：2000-04-01 00:00:00

abstract：:A DNA vaccine plasmid containing the Japanese encephalitis (JE) virus premembrane (prM) and envelope (E) genes (designated pcDNA3JEME) was evaluated for immunogenicity and protective efficacy in mice. Two immunizations of 4-week-old female ICR mice with pcDNA3JEME by intramuscular or intradermal injections at a dose o...

journal_title：Journal of virology

authors： Konishi E,Yamaoka M,Khin-Sane-Win,Kurane I,Mason PW

更新日期：1998-06-01 00:00:00

abstract：:Analyses of prototype vesicular stomatitis (VSV, Indiana serotype) mRNA-32P-labeled viral RNA duplexes have established the assignments of 65 of the 72 large oligonucleotides that are recovered by two-dimensional electrophoresis of RNase T1 digests of the viral RNA. Fifty of the oligonucleotides are recovered in the L...

journal_title：Journal of virology

authors： Clewley JP,Bishop DH

更新日期：1979-04-01 00:00:00

abstract：UNLABELLED:Influenza virus hemagglutinin (HA) mediates virus entry by binding to cell surface receptors and fusing the viral and endosomal membranes following uptake by endocytosis. The acidic environment of endosomes triggers a large-scale conformational change in the transmembrane subunit of HA (HA2) involving a loop...

journal_title：Journal of virology

authors： Wang W,DeFeo CJ,Alvarado-Facundo E,Vassell R,Weiss CD

更新日期：2015-10-01 00:00:00

abstract：:A recombinant capripoxvirus vaccine containing a cDNA of the peste-des-petits-ruminants virus (PPRV) fusion protein gene was constructed. A quick and efficient method was used to select a highly purified recombinant virus clone. A trial showed that a dose of this recombinant as low as 0.1 PFU protected goats against c...

journal_title：Journal of virology

authors： Berhe G,Minet C,Le Goff C,Barrett T,Ngangnou A,Grillet C,Libeau G,Fleming M,Black DN,Diallo A

更新日期：2003-01-01 00:00:00

abstract：:A temperature-sensitive mutant of adenovirus 31 was defective in formation of the DNA replication complex, suggesting the existence of a virus-coded protein necessary for the complex-formation. ...

journal_title：Journal of virology

authors： Suzuki E,Shimojo H

更新日期：1974-02-01 00:00:00

abstract：:DNA of the avian hepadnavirus, duck hepatitis B virus, was found to be integrated at low abundance into the cellular DNA extracted from the livers of infected ducklings. The frequency of integration was estimated to be at least one viral genome per 10(3) to 10(4) cells by 6 days postinfection. The structures of virus-...

journal_title：Journal of virology

authors： Yang W,Summers J

更新日期：1999-12-01 00:00:00

abstract：:Viruses efficiently block the host antiviral response in order to replicate and spread before host intervention. The mechanism initiating antiviral immunity during stealth viral replication is unknown, but recent data demonstrate that defective viral genomes generated at peak virus replication are critical for this pr...

journal_title：Journal of virology

authors： López CB

更新日期：2014-08-01 00:00:00

abstract：:The v-rel oncogene encoded by reticuloendotheliosis virus strain T is the acutely transforming member of the Rel/NF-kappaB family of transcription factors. In v-Rel-transformed cells, v-Rel exists as homodimers or heterodimers with the endogenous Rel/NF-kappaB proteins c-Rel, NF-kappaB1, NF-kappaB2, and RelA. To exami...

journal_title：Journal of virology

authors： Liss AS,Bose HR Jr

更新日期：2002-05-01 00:00:00

abstract：:We compared the proteins which associate with middle T antigen (MT) of polyomavirus in human cells infected with Ad5(pymT), a recombinant adenovirus which directs the overexpression of MT, with the MT-associated proteins (MTAPs) previously identified in murine fibroblasts expressing MT. MTAPs of 27, 29, 36, and 63 kil...

journal_title：Journal of virology

authors： Pallas DC,Morgan W,Roberts TM

更新日期：1989-11-01 00:00:00

abstract：:Recombinant rotavirus (RV) with cDNA-derived chimeric VP4 was generated using recently developed reverse genetics for RV. The rescued virus, KU//rVP4(SA11)-II(DS-1), contains SA11 (simian RV strain, G3P[2])-based VP4, in which a cross-reactive neutralization epitope (amino acids 381 to 401) on VP5* is replaced by the ...

journal_title：Journal of virology

authors： Komoto S,Kugita M,Sasaki J,Taniguchi K

更新日期：2008-07-01 00:00:00

abstract：:Protective immunity to rotavirus (RV) is primarily mediated by antibodies produced by RV-specific memory B cells (RV-mBc). Of note, most of these cells express IgM, but the function of this subset is poorly understood. Here, using limiting dilution assays of highly sort-purified human IgM(+) mBc, we found that 62% and...

journal_title：Journal of virology

authors： Narváez CF,Feng N,Vásquez C,Sen A,Angel J,Greenberg HB,Franco MA

更新日期：2012-10-01 00:00:00

abstract：:Vesicular stomatitis virus Indiana strain G protein (VSVind.G) is the most commonly used envelope glycoprotein to pseudotype lentiviral vectors (LV) for experimental and clinical applications. Recently, G proteins derived from other vesiculoviruses (VesG), for example, Cocal virus, have been proposed as alternative LV...

journal_title：Journal of virology

authors： Munis AM,Tijani M,Hassall M,Mattiuzzo G,Collins MK,Takeuchi Y

更新日期：2018-11-12 00:00:00

abstract：:The sheep genome harbors approximately 20 endogenous retroviruses (enJSRVs) highly related to the exogenous Jaagsiekte sheep retrovirus (JSRV). One of the enJSRV loci, enJS56A1, acts as a unique restriction factor by blocking JSRV in a transdominant fashion at a late stage of the retroviral cycle. To better understand...

journal_title：Journal of virology

authors： Murcia PR,Arnaud F,Palmarini M

更新日期：2007-02-01 00:00:00