Association between the behavioral and neurochemical effects of amphetamine: hemispheric asymmetry study.

Abstract:

:Effects of amphetamine on concentrations of dopamine, norepinephrine and serotonin in several monoamine-containing cell body and terminal regions were examined left and right separately in rats. Results suggest that amphetamine reduced the L-R asymmetry of most of these measures, and this effect is more significant in the cell body than in the terminal regions. Behaviorally, amphetamine also decreased L-R asymmetry of the spontaneous turning behavior in rats and this latter effect is most closely associated with the reductions of dopamine and norepinephrine asymmetries in the substantia nigra and reduction of norepinephrine asymmetry in the locus coeruleus.

journal_name

Life Sci

journal_title

Life sciences

authors

Lee EH,Huang SL,Chai CY

doi

10.1016/0024-3205(87)90334-1

subject

Has Abstract

pub_date

1987-04-06 00:00:00

pages

1431-7

issue

14

eissn

0024-3205

issn

1879-0631

pii

0024-3205(87)90334-1

journal_volume

40

pub_type

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